Agnes Noy
@agnesnoy.bsky.social
Senior Lecturer at the University of York. DNA, protein-DNA, biophysics, modeling, supercoiling, and much more
Pinned
MRC DiMeN Doctoral Training Partnership: Computational Drug Discovery Targeting DNA Gyrase to Tackle Antimicrobial Resistance at University of York on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Computational Drug Discovery Targeting DNA Gyrase to Tackle Antimicrobial Resistance at University of York, listed on FindAPhD.com
www.findaphd.com
Would you like to fight against antimicrobial resistance (AMR) developing antibiotics? Apply to the PhD opportunity below and come to York. Collaboration with colegroupncl.bsky.social, @dghilarov.bsky.social and Inspiralis Ltd.
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
Reposted by Agnes Noy
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
November 9, 2025 at 5:20 PM
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
Would you like to fight against antimicrobial resistance (AMR) developing antibiotics? Apply to the PhD opportunity below and come to York. Collaboration with colegroupncl.bsky.social, @dghilarov.bsky.social and Inspiralis Ltd.
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Computational Drug Discovery Targeting DNA Gyrase to Tackle Antimicrobial Resistance at University of York on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Computational Drug Discovery Targeting DNA Gyrase to Tackle Antimicrobial Resistance at University of York, listed on FindAPhD.com
www.findaphd.com
November 3, 2025 at 8:52 AM
Would you like to fight against antimicrobial resistance (AMR) developing antibiotics? Apply to the PhD opportunity below and come to York. Collaboration with colegroupncl.bsky.social, @dghilarov.bsky.social and Inspiralis Ltd.
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
Fully funded via DiMeN DTP 💡
www.findaphd.com/phds/project...
Check our latest publication in #JACSAu @ACSPublications with Elliot Chan and @bpsiyork.bsky.social, where we describe how the bacterial protein HU binds DNA at atomic resolution. Thanks to EPSRC for funds and @n8cir.bsky.social and hecbiosim for computational resources. pubs.acs.org/doi/10.1021/...
October 30, 2025 at 3:01 PM
Check our latest publication in #JACSAu @ACSPublications with Elliot Chan and @bpsiyork.bsky.social, where we describe how the bacterial protein HU binds DNA at atomic resolution. Thanks to EPSRC for funds and @n8cir.bsky.social and hecbiosim for computational resources. pubs.acs.org/doi/10.1021/...
Reposted by Agnes Noy
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere!
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
September 18, 2025 at 11:14 PM
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere!
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
Reposted by Agnes Noy
Our community letter on #FAIR principles in #moleculardynamics simulations has been published on @naturemethods.bsky.social 🎉
📢 Our article calling for a #FAIR database for #MolecularDynamics simulation data has now been peer-reviewed and published in @naturemethods.bsky.social
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
📖 Read it here: rdcu.be/ef6YX
📝 Support the statement: bit.ly/3zVS3qm
#MDDB #FAIRdata #collaboration
April 5, 2025 at 9:56 AM
Our community letter on #FAIR principles in #moleculardynamics simulations has been published on @naturemethods.bsky.social 🎉
This is one of the conferences where I have genuinely learned more. Delighted to contribute to this vision article.
In @molecularmicro.bsky.social: two special issues on Prokaryotic Chromosome Organization. Many excellent contributions, including a vision article: 'Future directions of the Prokaryotic Chromosome Field', outcome of BioPhyChrom 2023 @biophychrom.bsky.social onlinelibrary.wiley.com/doi/10.1111/...
Future Directions of the Prokaryotic Chromosome Field
In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of ....
onlinelibrary.wiley.com
February 21, 2025 at 8:20 AM
This is one of the conferences where I have genuinely learned more. Delighted to contribute to this vision article.
Were you interested in our last paper published in Phys. Rev. Lett. (with Matthew Burman at the University of York) but found it too hard to follow? Then, look at the piece from @sciencex.bsky.social where it is explained in more plain terms with the help of Ingrid Fadelli
Molecular simulations have unveiled how torsional stress influences supercoiled DNA, revealing that AT-rich sequences form bubbles more easily, facilitating genetic information access. doi.org/g83xvv
Molecular simulations provide new insights into the dynamics of supercoiled DNA
DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, development, reproduction and predispositions of individual humans, can undergo different types of mechanical stress inside cells.
phys.org
February 6, 2025 at 10:05 AM
Were you interested in our last paper published in Phys. Rev. Lett. (with Matthew Burman at the University of York) but found it too hard to follow? Then, look at the piece from @sciencex.bsky.social where it is explained in more plain terms with the help of Ingrid Fadelli
Our last paper just appeared in Physical Review Letters. We studied how linear DNA is distorted by torsion and tension using all-atom simulations. Excellent work from Matthew Burman's EPSRC-funded PhD. Thanks to N8 CIR and HecBiosim for computational resources
doi.org/10.1103/Phys...
See thread 👇
doi.org/10.1103/Phys...
See thread 👇
Atomic Description of the Reciprocal Action between Supercoils and Melting Bubbles on Linear DNA
Although the mechanical response of DNA to physiological torsion and tension is well characterized, the detailed structures are not yet known. By using molecular dynamics simulations on linear DNA wit...
doi.org
January 27, 2025 at 5:05 PM
Our last paper just appeared in Physical Review Letters. We studied how linear DNA is distorted by torsion and tension using all-atom simulations. Excellent work from Matthew Burman's EPSRC-funded PhD. Thanks to N8 CIR and HecBiosim for computational resources
doi.org/10.1103/Phys...
See thread 👇
doi.org/10.1103/Phys...
See thread 👇
I am very excited that I will participate in this workshop!
🚨🚨Please repost!! 📢📢
Following last year’s success, International workshop Physics of Biological Systems is back in May! Free registration! Submit talk or poster abstract. Join us in Edinburgh
@edinburgh-uni.bsky.social
bit.ly/EdinPBS2025
Following last year’s success, International workshop Physics of Biological Systems is back in May! Free registration! Submit talk or poster abstract. Join us in Edinburgh
@edinburgh-uni.bsky.social
bit.ly/EdinPBS2025
January 24, 2025 at 8:37 AM
I am very excited that I will participate in this workshop!
Reposted by Agnes Noy
Registration is now open for The Biology and Physics of Prokaryotic Chromosomes meeting in York, UK. 16-19 September 2025
January 22, 2025 at 6:49 AM
Registration is now open for The Biology and Physics of Prokaryotic Chromosomes meeting in York, UK. 16-19 September 2025