Agnes Noy
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agnesnoy.bsky.social
Agnes Noy
@agnesnoy.bsky.social
Senior Lecturer at the University of York. DNA, protein-DNA, biophysics, modeling, supercoiling, and much more
Check our latest publication in #JACSAu @ACSPublications with Elliot Chan and @bpsiyork.bsky.social, where we describe how the bacterial protein HU binds DNA at atomic resolution. Thanks to EPSRC for funds and @n8cir.bsky.social and hecbiosim for computational resources. pubs.acs.org/doi/10.1021/...
October 30, 2025 at 3:01 PM
We also describe the dynamics and diffusion of supercoils. Big end-to-end fluctuations are caused by supercoil reorganization as described by
Lipfert and @ecarlon.bsky.social labs (5/6)
January 27, 2025 at 5:05 PM
This state converges to tip-bubbles as tension increases in agreement with previous oxDNA simulations from Doye and Louis labs 👇 (again, bubbles in red) (4/6)
January 27, 2025 at 5:05 PM