Alexandre Djiane
@adjiane.bsky.social
Group Leader at IRCM (Montpellier, France) working on Epithelial Growth and Cancer
A lot of Drosophila, a little bit of Mouse
Growth, Cell signalling, Inter-organ communications
A lot of Drosophila, a little bit of Mouse
Growth, Cell signalling, Inter-organ communications
Reposted by Alexandre Djiane
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
October 15, 2025 at 12:22 PM
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
Reposted by Alexandre Djiane
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
October 7, 2025 at 5:49 PM
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Reposted by Alexandre Djiane
We have had a great final morning at #EDRC2025 with three fantastic keynote lectures by Maria Gambetta, Tor Erik Rusten and Silke Sachse
September 28, 2025 at 2:44 PM
We have had a great final morning at #EDRC2025 with three fantastic keynote lectures by Maria Gambetta, Tor Erik Rusten and Silke Sachse
Reposted by Alexandre Djiane
3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!
September 25, 2025 at 4:09 PM
3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!
Reposted by Alexandre Djiane
Read the article ‘Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions’ here: doi.org/10.1242/dev....
Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions
Highlighted Article: Localization of the cell-adhesion molecule Sidekick to tricellular adherens junctions requires specific extracellular domains and its intracellular binding partner, the PAK4 kinas...
doi.org
September 22, 2025 at 7:25 PM
Read the article ‘Mushroom bodies tiny regulates Sidekick localization to tricellular adherens junctions’ here: doi.org/10.1242/dev....
Reposted by Alexandre Djiane
Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
August 30, 2025 at 3:47 PM
Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
After manuscript reviews full of inaccuracies which appear AI generated, and final grant rejection (despite excellent reviews), I will let the disappointment and anger pass, and will not review your manuscript tonight. I apologise for the potential delay, but you might thank me later.
July 17, 2025 at 2:27 PM
After manuscript reviews full of inaccuracies which appear AI generated, and final grant rejection (despite excellent reviews), I will let the disappointment and anger pass, and will not review your manuscript tonight. I apologise for the potential delay, but you might thank me later.
Reposted by Alexandre Djiane
I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️.
Thread below🧵
1/8
www.biorxiv.org/content/10.1...
Thread below🧵
1/8
www.biorxiv.org/content/10.1...
Multi-omic mapping of Drosophila protein secretomes reveals tissue-specific origins and inter-organ trafficking
Secreted proteins regulate many aspects of animal biology and are attractive targets for biomarkers and therapeutics. However, comprehensively identifying the "secretome", along with their tissues of ...
www.biorxiv.org
July 11, 2025 at 2:51 PM
I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️.
Thread below🧵
1/8
www.biorxiv.org/content/10.1...
Thread below🧵
1/8
www.biorxiv.org/content/10.1...
Reposted by Alexandre Djiane
Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila
Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing,
which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication
stress. Drosophila wing ...
www.cell.com
June 5, 2025 at 4:47 PM
Very happy to share our latest lab publication!
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
The hard work of @bboumard.bsky.social, Gwenn Le Meur and collaborators!
Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila: Developmental Cell
authors.elsevier.com/a/1lDFi_Yv6z...
Reposted by Alexandre Djiane
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis
#Drosophila
#Drosophila
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis
#Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
June 4, 2025 at 5:23 AM
Serotonergic neurons regulate the Drosophila vascular niche to control immune stress hematopoiesis
#Drosophila
#Drosophila
Reposted by Alexandre Djiane
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 4:15 PM
#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!
www.philanthropy.cam.ac.uk/give-to-camb...
Reposted by Alexandre Djiane
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
Drosophila Genetic Database
The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...
www.philanthropy.cam.ac.uk
June 3, 2025 at 6:23 PM
Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...
Reposted by Alexandre Djiane
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
May 21, 2025 at 9:40 AM
Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Alexandre Djiane
📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
May 15, 2025 at 8:16 AM
📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Reposted by Alexandre Djiane
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
April 10, 2025 at 6:06 AM
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Reposted by Alexandre Djiane
Thrilled to present our study aiming to identify new vulnerabilities in lung cancer: www.biorxiv.org/content/10.1...
Joining forces from mouse genetics, thoracic oncology,
metabolism, and AlphaFold fields we dissected the role of a largely unknown but essential protein in cancer, FMO4.🧵
Joining forces from mouse genetics, thoracic oncology,
metabolism, and AlphaFold fields we dissected the role of a largely unknown but essential protein in cancer, FMO4.🧵
www.biorxiv.org
April 3, 2025 at 7:33 AM
Thrilled to present our study aiming to identify new vulnerabilities in lung cancer: www.biorxiv.org/content/10.1...
Joining forces from mouse genetics, thoracic oncology,
metabolism, and AlphaFold fields we dissected the role of a largely unknown but essential protein in cancer, FMO4.🧵
Joining forces from mouse genetics, thoracic oncology,
metabolism, and AlphaFold fields we dissected the role of a largely unknown but essential protein in cancer, FMO4.🧵
Reposted by Alexandre Djiane
Retour en images sur le discours notre président Patrick Lemaire lors du rassemblement #StandUpForScience #7Mars devant l'opéra Comédie à 18h à #Montpellier où nous étions nombreux, en plus des 4 rassemblements du midi
March 8, 2025 at 2:25 PM
Retour en images sur le discours notre président Patrick Lemaire lors du rassemblement #StandUpForScience #7Mars devant l'opéra Comédie à 18h à #Montpellier où nous étions nombreux, en plus des 4 rassemblements du midi
Reposted by Alexandre Djiane
We keep standing up for Sciences in Montpellier @standupforscifr.bsky.social
March 7, 2025 at 6:36 PM
We keep standing up for Sciences in Montpellier @standupforscifr.bsky.social
Reposted by Alexandre Djiane
Stand Up for Science France protest this Friday March 7.
Numerous actions throughout France including a protest march in Paris starting at Jussieu 13h30 by @sufs-paris-rp.bsky.social
@standupforscience.bsky.social
👉 standupforscience.fr #StandUpForScience #StandUpForScienceFrance
Numerous actions throughout France including a protest march in Paris starting at Jussieu 13h30 by @sufs-paris-rp.bsky.social
@standupforscience.bsky.social
👉 standupforscience.fr #StandUpForScience #StandUpForScienceFrance
Stand Up For Science France | Le 7 mars, nous défendons les sciences – parce que les sciences sont un bien commun.
standupforscience.fr
March 4, 2025 at 8:18 AM
Stand Up for Science France protest this Friday March 7.
Numerous actions throughout France including a protest march in Paris starting at Jussieu 13h30 by @sufs-paris-rp.bsky.social
@standupforscience.bsky.social
👉 standupforscience.fr #StandUpForScience #StandUpForScienceFrance
Numerous actions throughout France including a protest march in Paris starting at Jussieu 13h30 by @sufs-paris-rp.bsky.social
@standupforscience.bsky.social
👉 standupforscience.fr #StandUpForScience #StandUpForScienceFrance
Reposted by Alexandre Djiane
L’Inserm rejoint Bluesky !
Découvrez ici toutes les actualités de la recherche médicale menée par l’Inserm, pour la santé de toutes et tous.
Découvrez ici toutes les actualités de la recherche médicale menée par l’Inserm, pour la santé de toutes et tous.
February 25, 2025 at 4:11 PM
L’Inserm rejoint Bluesky !
Découvrez ici toutes les actualités de la recherche médicale menée par l’Inserm, pour la santé de toutes et tous.
Découvrez ici toutes les actualités de la recherche médicale menée par l’Inserm, pour la santé de toutes et tous.
Reposted by Alexandre Djiane
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details.
(1/5)
(1/5)
February 25, 2025 at 7:25 PM
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details.
(1/5)
(1/5)
Reposted by Alexandre Djiane
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Noninvasive characterization of oocyte deformability in microconstrictions
A microfluidic measurement method translates oocyte mechanical characterization into oocyte quality assessment.
www.science.org
February 20, 2025 at 7:11 AM
Check out our latest paper in Science Advances, in which we built a constriction-based microfluidic device to measure the deformability of oocytes to assess their mechanical properties with minimal impact.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Alexandre Djiane
Check out our most recent preprint where we describe Mecp2 as a régulatrice of cGAS-STING associated signaling. 🧪🔥
The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling https://www.biorxiv.org/content/10.1101/2025.01.30.635818v1
February 5, 2025 at 7:48 PM
Check out our most recent preprint where we describe Mecp2 as a régulatrice of cGAS-STING associated signaling. 🧪🔥
Reposted by Alexandre Djiane
Our latest extraordinary biologist is Sarah Bray, Chair of our Board of Directors. To learn more about Sarah's role and relationship with @biologists.bsky.social, read this interview in @dev-journal.bsky.social: bit.ly/3CEibaX.
#100biologists
@uniofcam.bsky.social
#100biologists
@uniofcam.bsky.social
February 4, 2025 at 11:04 AM
Our latest extraordinary biologist is Sarah Bray, Chair of our Board of Directors. To learn more about Sarah's role and relationship with @biologists.bsky.social, read this interview in @dev-journal.bsky.social: bit.ly/3CEibaX.
#100biologists
@uniofcam.bsky.social
#100biologists
@uniofcam.bsky.social