Long, J., Jones, S. G., Serna, A., ..., Verstreken, P., Huynen, M. A., Luhy, K., Coll-Tane, M., Schenck, A. (2025). A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism. Dis Model Mech, journals.biologists.com/dmm/article/...
November 19, 2025 at 11:09 PM
Long, J., Jones, S. G., Serna, A., ..., Verstreken, P., Huynen, M. A., Luhy, K., Coll-Tane, M., Schenck, A. (2025). A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism. Dis Model Mech, journals.biologists.com/dmm/article/...
Epilepsy is associated with significantly increased long-term risk of cardiovascular disease.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #cardiovasculardiseases #riskfactors #SouthKorea
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #cardiovasculardiseases #riskfactors #SouthKorea
November 19, 2025 at 7:04 PM
Epilepsy is associated with significantly increased long-term risk of cardiovascular disease.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #cardiovasculardiseases #riskfactors #SouthKorea
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #cardiovasculardiseases #riskfactors #SouthKorea
Online now: Plasma proteomics identifies proteins and pathways associated with incident epilepsy
Plasma proteomics identifies proteins and pathways associated with incident epilepsy
Zhang et al. utilize large-scale plasma proteomic data to investigate the association between 2,920 plasma proteins and the risk of incident epilepsy. They characterize the temporal trajectories of epilepsy-associated protein levels preceding disease onset and perform clustering analysis. Ultimately, they develop a protein-based predictive model for assessing future epilepsy risk.
dlvr.it
November 18, 2025 at 1:27 PM
Online now: Plasma proteomics identifies proteins and pathways associated with incident epilepsy
I came across this summary that pulls together some of the recent findings on the links between commonplace (including ostensibly "harmless") pathogens and long-term harm to human health. The war on infectious diseases is far from over!
November 16, 2025 at 12:52 PM
I came across this summary that pulls together some of the recent findings on the links between commonplace (including ostensibly "harmless") pathogens and long-term harm to human health. The war on infectious diseases is far from over!
chat they gave me dog pills
![the wikipedia entry for Gabapentin, section titled "Veterinary use" as follows:
Veterinary use
In cats, gabapentin can be used as an analgesic in multi-modal pain management,[177] anxiety medication to reduce stress during travel or vet visits,[178] and anticonvulsant.[179]
Veterinarians may prescribe gabapentin as an anticonvulsant and pain reliever in dogs.[180][179] It has beneficial effects for treating epilepsy, different kinds of pain (chronic, neuropathic, and post-operative pain), and anxiety, lip-licking behavior, storm phobia, fear-based aggression.[181][182]
It is also used to treat chronic pain-associated nerve inflammation in horses and dogs. Side effects include tiredness and loss of coordination, but these effects generally resolve within 24 hours of starting the medication.[180][179]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:nmv6s6zzpqwuavbrnprhycf3/bafkreihxtheabc47c7nwsodfkr65w2xux2jmc2ckkryv5svsuyb77rycc4@jpeg)
November 16, 2025 at 12:49 AM
chat they gave me dog pills
Plasma proteomics study identifies 23 proteins differentially expressed in epilepsy patients with recent seizures compared to those seizure-free for over a year. Machine learning models pinpointed 51 unique proteins associated with seizure status.
November 14, 2025 at 9:40 PM
Plasma proteomics study identifies 23 proteins differentially expressed in epilepsy patients with recent seizures compared to those seizure-free for over a year. Machine learning models pinpointed 51 unique proteins associated with seizure status.
My suspected thing is focal epilepsy, I have a lot of synesthesias, both associative and projective, too many probably, a possible cavernoma in my left temporal lobe (associated w among other things auditory hallucinations) & TLE/seizures run through both sides of the family
November 14, 2025 at 8:08 PM
My suspected thing is focal epilepsy, I have a lot of synesthesias, both associative and projective, too many probably, a possible cavernoma in my left temporal lobe (associated w among other things auditory hallucinations) & TLE/seizures run through both sides of the family
Physical activity effects mortality risk in epilepsy
https://www.newsbeep.com/ie/134154/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
https://www.newsbeep.com/ie/134154/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
Physical activity effects mortality risk in epilepsy - Ireland News Beep
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various physical and mental
www.newsbeep.com
November 11, 2025 at 3:15 PM
Physical activity effects mortality risk in epilepsy
https://www.newsbeep.com/ie/134154/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
https://www.newsbeep.com/ie/134154/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
Physical activity effects mortality risk in epilepsy
https://www.newsbeep.com/nz/129719/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
https://www.newsbeep.com/nz/129719/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
Physical activity effects mortality risk in epilepsy - New Zealand News Beep
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various physical and mental
www.newsbeep.com
November 11, 2025 at 3:15 PM
Physical activity effects mortality risk in epilepsy
https://www.newsbeep.com/nz/129719/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
https://www.newsbeep.com/nz/129719/
Exercise has traditionally been associated with better health outcomes. According to the World Health Organization, there are various…
Epilepsy incidence among US Medicare beneficiaries aged 65 and older varied tenfold across regions and was associated with insufficient sleep, lack of vehicle access, heat index, physical inactivity, and uninsured rate. ja.ma/4hK4MhL
November 11, 2025 at 2:00 PM
Epilepsy incidence among US Medicare beneficiaries aged 65 and older varied tenfold across regions and was associated with insufficient sleep, lack of vehicle access, heat index, physical inactivity, and uninsured rate. ja.ma/4hK4MhL
One of the definitions from Oxford:
"Psychiatry: a state or period of loss of awareness of one's identity, often coupled with flight from one's usual environment, associated with certain forms of hysteria and epilepsy."
I'd say there's a lot of it going on these days.
"Psychiatry: a state or period of loss of awareness of one's identity, often coupled with flight from one's usual environment, associated with certain forms of hysteria and epilepsy."
I'd say there's a lot of it going on these days.
November 9, 2025 at 11:38 PM
One of the definitions from Oxford:
"Psychiatry: a state or period of loss of awareness of one's identity, often coupled with flight from one's usual environment, associated with certain forms of hysteria and epilepsy."
I'd say there's a lot of it going on these days.
"Psychiatry: a state or period of loss of awareness of one's identity, often coupled with flight from one's usual environment, associated with certain forms of hysteria and epilepsy."
I'd say there's a lot of it going on these days.
Comorbidities like type 1 diabetes and epilepsy were associated with higher likelihood of treatment.
November 7, 2025 at 12:59 PM
Comorbidities like type 1 diabetes and epilepsy were associated with higher likelihood of treatment.
📣 The November issue of International Health is now available online!
Keep reading, here: www.rstmh.org/news-blog/bl...
Keep reading, here: www.rstmh.org/news-blog/bl...
November 7, 2025 at 9:51 AM
📣 The November issue of International Health is now available online!
Keep reading, here: www.rstmh.org/news-blog/bl...
Keep reading, here: www.rstmh.org/news-blog/bl...
[Highlight of the Month] Jung et al.: Stronger pre-surgical functional connectivity networks are associated with improved surgical outcome in temporal lobe epilepsy. Clin Neurophysiol 2025;179:2110980. Open access: doi.org/10.1016/j.cl...
November 4, 2025 at 1:09 PM
[Highlight of the Month] Jung et al.: Stronger pre-surgical functional connectivity networks are associated with improved surgical outcome in temporal lobe epilepsy. Clin Neurophysiol 2025;179:2110980. Open access: doi.org/10.1016/j.cl...
Bexicaserin, a highly selective 5HT2C receptor superagonist, is an investigational molecule in clinical development that has progressed to phase 3 for the treatment of seizures associated with DEEs.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #bexicaserin #DEE #seizures #serotonin
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #bexicaserin #DEE #seizures #serotonin
November 3, 2025 at 7:30 PM
Bexicaserin, a highly selective 5HT2C receptor superagonist, is an investigational molecule in clinical development that has progressed to phase 3 for the treatment of seizures associated with DEEs.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #bexicaserin #DEE #seizures #serotonin
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #bexicaserin #DEE #seizures #serotonin
Researchers find brain injury-related epilepsy associated with higher risk of death. Dr. Zulfi Haneef explains. https://bit.ly/43tS2Gb #epilepsy
MSN
bit.ly
November 1, 2025 at 2:40 PM
Researchers find brain injury-related epilepsy associated with higher risk of death. Dr. Zulfi Haneef explains. https://bit.ly/43tS2Gb #epilepsy
Post-traumatic epilepsy (PTE) has previously been associated with severe TBI. But new evidence suggests even mild and moderate TBIs can lead to epilepsy, sometimes months or years after the initial injury. #concussion #braintrauma #braininjury www.lexology.com/library/deta...
Post-traumatic epilepsy after mild and moderate TBI: is there a causal link?
A recent narrative review published in Clinics and Practice (MDPI) offers a reassessment of the risk of post-traumatic epilepsy (PTE) following mild…
www.lexology.com
November 1, 2025 at 12:07 PM
Post-traumatic epilepsy (PTE) has previously been associated with severe TBI. But new evidence suggests even mild and moderate TBIs can lead to epilepsy, sometimes months or years after the initial injury. #concussion #braintrauma #braininjury www.lexology.com/library/deta...
Brain injury-related epilepsy associated with higher risk of death https://www.upi.com/Health_News/2025/10/30/veterans-epilepsy-brain-injury-death-risk/8891761829830/
Brain injury-related epilepsy associated with higher risk of death - UPI.com
Military veterans who develop epilepsy following a traumatic brain injury might be more likely to die earlier than others with epilepsy, researchers reported.
www.upi.com
October 30, 2025 at 4:40 PM
Brain injury-related epilepsy associated with higher risk of death https://www.upi.com/Health_News/2025/10/30/veterans-epilepsy-brain-injury-death-risk/8891761829830/
Brain injury-related epilepsy associated with higher risk of death
www.upi.com
Brain injury-related epilepsy associated with higher risk of death - UPI.com
twp.ai
October 30, 2025 at 4:08 PM
Brain injury-related epilepsy associated with higher risk of death
Curious about the neural mechanisms behind deep brain stimulation (DBS)?
Prof. Kragelund will be sharing insights in a webinar about her high-density microelectrode array recordings, revealing how DBS modulates network connectivity and activity patterns in dystonia and glioma-associated epilepsy.
Prof. Kragelund will be sharing insights in a webinar about her high-density microelectrode array recordings, revealing how DBS modulates network connectivity and activity patterns in dystonia and glioma-associated epilepsy.
October 30, 2025 at 11:19 AM
Curious about the neural mechanisms behind deep brain stimulation (DBS)?
Prof. Kragelund will be sharing insights in a webinar about her high-density microelectrode array recordings, revealing how DBS modulates network connectivity and activity patterns in dystonia and glioma-associated epilepsy.
Prof. Kragelund will be sharing insights in a webinar about her high-density microelectrode array recordings, revealing how DBS modulates network connectivity and activity patterns in dystonia and glioma-associated epilepsy.
#kulturkampf #medizin
.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury #ecsl/tags/ECS" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity […]
[Original post on mastodon.social]
.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury #ecsl/tags/ECS" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity […]
[Original post on mastodon.social]
![Phytocannabinoids CBD and Δ9-THC
In addition to the phytocannabinoid Δ9-THC, it is estimated that the cannabis plant consists of over 400 chemical entities, of which more than 60 of them are phytocannabinoid compounds. Some of these compounds have been identified as acting uniquely on both CB1 and CB2 receptors separately and simultaneously, and/or to inhibit or activate receptor functions. CBD, like Δ9-THC, is a major phytocannabinoid accounting for up to 40% of the plant's extract. CBD was first discovered in 1940 more than 20 years before Δ9-THC.[104,105] Until recently, Δ9-THC dominated cannabis research. All classes of phytocannabinoid compounds found in marijuana and hemp, including Δ9-THC and CBD, are derived from various changes to base molecular structure of cannabigerol-type compounds [Figure 1].[34,49]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cwg2zyfzx2hljvnhavdzeft4/bafkreia57mbt2zz5imp64qvmr5loxs2g3crxwivnt2ijzlhy5s2gpwdfby@jpeg)
October 28, 2025 at 12:06 PM
#kulturkampf #medizin
.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury #ecsl/tags/ECS" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity […]
[Original post on mastodon.social]
.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury #ecsl/tags/ECS" class="hover:underline text-blue-600 dark:text-sky-400 no-card-link" target="_blank" rel="noopener" data-link="bsky">Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity […]
[Original post on mastodon.social]
Learn how to manage glioma-associated epilepsy with effective strategies that can enhance the quality of life for those affected. #epilepsyexplained #epilepsy 💜.
Understanding Glioma-Associated Epilepsy and Its Management - Epilepsy Explained 💜
Discover effective strategies for Glioma Associated Epilepsy Management and improve quality of life for those affected by gliomas.
epilepsyexplained.com
October 23, 2025 at 12:43 AM
Learn how to manage glioma-associated epilepsy with effective strategies that can enhance the quality of life for those affected. #epilepsyexplained #epilepsy 💜.
Progressive clonic slowing is associated with marked oxygen desaturation during bilateral tonic–clonic seizures.
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #SUDEP #Progressiveclonicslowing #PostictalImmobility #Tonicclonicseizure #Respiratorydysfunction
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #SUDEP #Progressiveclonicslowing #PostictalImmobility #Tonicclonicseizure #Respiratorydysfunction
October 22, 2025 at 7:22 PM
Progressive clonic slowing is associated with marked oxygen desaturation during bilateral tonic–clonic seizures.
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #SUDEP #Progressiveclonicslowing #PostictalImmobility #Tonicclonicseizure #Respiratorydysfunction
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #SUDEP #Progressiveclonicslowing #PostictalImmobility #Tonicclonicseizure #Respiratorydysfunction
In general, local GMV differences were positively associated with epileptogenic zone (EZ) contacts in the whole cohort and MRI-positive patients, but not in MRI-negative patients.
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #biomarker #graymattervolume #MRI #stereoEEG #voxelbasedmorphometry
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #biomarker #graymattervolume #MRI #stereoEEG #voxelbasedmorphometry
October 22, 2025 at 7:20 PM
In general, local GMV differences were positively associated with epileptogenic zone (EZ) contacts in the whole cohort and MRI-positive patients, but not in MRI-negative patients.
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #biomarker #graymattervolume #MRI #stereoEEG #voxelbasedmorphometry
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #biomarker #graymattervolume #MRI #stereoEEG #voxelbasedmorphometry
Shah, N., Kovalchuk, V., Zerlotti, R., ..., Hummel, T., Kasture, A. S., Sucic, S. (2025). Rescue of Epilepsy-Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1. Faseb j, 39(11):e70614 faseb.onlinelibrary.wiley.com/doi/10.1096/...
Rescue of Epilepsy‐Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1
Mutations in the human GABA transporter 1 (hGAT-1) gene impair GABA transport, leading to developmental disorders like epilepsy and autism. These mutations often disrupt protein folding. Pharmacochap...
faseb.onlinelibrary.wiley.com
October 21, 2025 at 8:45 PM
Shah, N., Kovalchuk, V., Zerlotti, R., ..., Hummel, T., Kasture, A. S., Sucic, S. (2025). Rescue of Epilepsy-Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1. Faseb j, 39(11):e70614 faseb.onlinelibrary.wiley.com/doi/10.1096/...