Our circadian clock and cancer chronotherapy, a terrific
@scripps.edu review, open-access, related to below!
jci.org/articles/vie...
@scripps.edu review, open-access, related to below!
jci.org/articles/vie...
February 3, 2026 at 9:27 PM
Our circadian clock and cancer chronotherapy, a terrific
@scripps.edu review, open-access, related to below!
jci.org/articles/vie...
@scripps.edu review, open-access, related to below!
jci.org/articles/vie...
I would have similar effects from taking melatonin and sleeping outside of my body's anticipated sleep wake cycle, or from staying up later each day as part of chronotherapy back when i had untreated n24
November 15, 2023 at 11:15 PM
I would have similar effects from taking melatonin and sleeping outside of my body's anticipated sleep wake cycle, or from staying up later each day as part of chronotherapy back when i had untreated n24
As always it is quiet time after taking my daily Chronotherapy tablet as I learnt the hard way what happens if I do not sit quietly. Still a sobering thought I will have to do this for the rest of my life and no wonder sometimes I have difficulty holding things together.
February 22, 2024 at 9:01 PM
As always it is quiet time after taking my daily Chronotherapy tablet as I learnt the hard way what happens if I do not sit quietly. Still a sobering thought I will have to do this for the rest of my life and no wonder sometimes I have difficulty holding things together.
These findings highlight the potential for chronotherapy, or timing treatments to align with the body's natural rhythms, to enhance the efficacy and safety of chemotherapy.
August 2, 2025 at 1:09 AM
These findings highlight the potential for chronotherapy, or timing treatments to align with the body's natural rhythms, to enhance the efficacy and safety of chemotherapy.
#BestEvidence webinar recording
Debunking some of the hype in #Hypertension
ti.ubc.ca/drugevidence24
Dr. James Wright summarizes latest evidence on #antihypertensives:
⏰ chronotherapy
💊 first line tx
🎯 blood pressure targets
⚠️ treatment efficacy + safety
#drugevidence24 #meded #medsafety
Debunking some of the hype in #Hypertension
ti.ubc.ca/drugevidence24
Dr. James Wright summarizes latest evidence on #antihypertensives:
⏰ chronotherapy
💊 first line tx
🎯 blood pressure targets
⚠️ treatment efficacy + safety
#drugevidence24 #meded #medsafety
Dr. James (Jim) Wright: Debunking some of the hype In hypertension
YouTube video by Therapeutics Initiative
youtu.be
March 4, 2025 at 8:07 PM
#BestEvidence webinar recording
Debunking some of the hype in #Hypertension
ti.ubc.ca/drugevidence24
Dr. James Wright summarizes latest evidence on #antihypertensives:
⏰ chronotherapy
💊 first line tx
🎯 blood pressure targets
⚠️ treatment efficacy + safety
#drugevidence24 #meded #medsafety
Debunking some of the hype in #Hypertension
ti.ubc.ca/drugevidence24
Dr. James Wright summarizes latest evidence on #antihypertensives:
⏰ chronotherapy
💊 first line tx
🎯 blood pressure targets
⚠️ treatment efficacy + safety
#drugevidence24 #meded #medsafety
🔍🤔Flip the #KYN switch to reboot immunity, metabolism & mood? 🧠🛠️We mapped cell checkpoints, chrono windows & #Probiotic+IDO/TDO combos that cut KYN & spare #KYNA🚀 @mdpiopenaccess.bsky.social #PrecisionMedicine #Microbiome #Chronotherapy
👉 Read & share! www.preprints.org/manuscript/2...
👉 Read & share! www.preprints.org/manuscript/2...
www.preprints.org
July 10, 2025 at 5:31 AM
🔍🤔Flip the #KYN switch to reboot immunity, metabolism & mood? 🧠🛠️We mapped cell checkpoints, chrono windows & #Probiotic+IDO/TDO combos that cut KYN & spare #KYNA🚀 @mdpiopenaccess.bsky.social #PrecisionMedicine #Microbiome #Chronotherapy
👉 Read & share! www.preprints.org/manuscript/2...
👉 Read & share! www.preprints.org/manuscript/2...
Morning matters? New research suggests timing your cancer treatment; especially immunotherapy… could impact its effectiveness. So next time you’re offered a slot, early might just be better than easy.
#CancerCare #Chronotherapy #Immunotherapy #TCSC #MorningMatters
time.com/7306220/canc...
#CancerCare #Chronotherapy #Immunotherapy #TCSC #MorningMatters
time.com/7306220/canc...
Is It Better to Get Cancer Treatment in the Morning?
"Appointment timing may in fact be a very big deal," write Drs. Christopher Worsham and Anupam Jena.
time.com
August 1, 2025 at 8:08 AM
Morning matters? New research suggests timing your cancer treatment; especially immunotherapy… could impact its effectiveness. So next time you’re offered a slot, early might just be better than easy.
#CancerCare #Chronotherapy #Immunotherapy #TCSC #MorningMatters
time.com/7306220/canc...
#CancerCare #Chronotherapy #Immunotherapy #TCSC #MorningMatters
time.com/7306220/canc...
What if your #Mood, #Memory & metabolism were hacked by #GutMicrobes?🧠🦠🧬💊⚡️This study maps kynurenine hotspots, adds “AI + #Probiotics🤖🧪 and unlocks chrono-dosing🕒 @mdpiopenaccess.bsky.social #GutBrainAxis #Microbiome #Chronotherapy #Neurobiology
👉 Read + share: www.preprints.org/manuscript/2...
👉 Read + share: www.preprints.org/manuscript/2...
www.preprints.org
June 26, 2025 at 5:31 AM
What if your #Mood, #Memory & metabolism were hacked by #GutMicrobes?🧠🦠🧬💊⚡️This study maps kynurenine hotspots, adds “AI + #Probiotics🤖🧪 and unlocks chrono-dosing🕒 @mdpiopenaccess.bsky.social #GutBrainAxis #Microbiome #Chronotherapy #Neurobiology
👉 Read + share: www.preprints.org/manuscript/2...
👉 Read + share: www.preprints.org/manuscript/2...
Chronotherapy – aka “wake therapy”. Used with 1000s of patients for depression and bipolar.
But what is it, and why is there a lack of research on this extremely tiring treatment?
👉 Read the first drop in The Morning After series. Sunday short hit.
whatareyouon.substack.com/p/can-sleep-...
But what is it, and why is there a lack of research on this extremely tiring treatment?
👉 Read the first drop in The Morning After series. Sunday short hit.
whatareyouon.substack.com/p/can-sleep-...
can Sleep Deprivation treat Depression?
On Reddit, it’s called sleeptripping. In clinics, it’s chronotherapy. Can staying awake really lift the blues?
whatareyouon.substack.com
September 14, 2025 at 9:22 AM
Chronotherapy – aka “wake therapy”. Used with 1000s of patients for depression and bipolar.
But what is it, and why is there a lack of research on this extremely tiring treatment?
👉 Read the first drop in The Morning After series. Sunday short hit.
whatareyouon.substack.com/p/can-sleep-...
But what is it, and why is there a lack of research on this extremely tiring treatment?
👉 Read the first drop in The Morning After series. Sunday short hit.
whatareyouon.substack.com/p/can-sleep-...
A fatal case of immune-mediated neuropathy showed symptom flares and inflammatory spikes after late-day PD-1 infusions, raising the idea of “chrono-immune neurotoxicity.”
Read more: www.cureus.com/articles/441...
#Cureus #Immunotherapy #Oncology #Neurology #Chronotherapy #MedSky
Read more: www.cureus.com/articles/441...
#Cureus #Immunotherapy #Oncology #Neurology #Chronotherapy #MedSky
December 31, 2025 at 12:19 PM
A fatal case of immune-mediated neuropathy showed symptom flares and inflammatory spikes after late-day PD-1 infusions, raising the idea of “chrono-immune neurotoxicity.”
Read more: www.cureus.com/articles/441...
#Cureus #Immunotherapy #Oncology #Neurology #Chronotherapy #MedSky
Read more: www.cureus.com/articles/441...
#Cureus #Immunotherapy #Oncology #Neurology #Chronotherapy #MedSky
I’m guest editing a joint issue in Neurobiology of Disease + Neurobiology of Sleep & Circadian Rhythms:
Topics: RBD, circuit dysfunction, early compensatory mechanisms, chronotherapy, lifestyle interventions & more.
📅 Dec 31, 2025
🔗 www.sciencedirect.com/special-issu...
DM if interested!
Topics: RBD, circuit dysfunction, early compensatory mechanisms, chronotherapy, lifestyle interventions & more.
📅 Dec 31, 2025
🔗 www.sciencedirect.com/special-issu...
DM if interested!
Neurobiology of Disease | ScienceDirect.com by Elsevier - Neurobiology of Disease | ScienceDirect.com by Elsevier
Read the latest articles of Neurobiology of Disease at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
June 27, 2025 at 8:15 AM
I’m guest editing a joint issue in Neurobiology of Disease + Neurobiology of Sleep & Circadian Rhythms:
Topics: RBD, circuit dysfunction, early compensatory mechanisms, chronotherapy, lifestyle interventions & more.
📅 Dec 31, 2025
🔗 www.sciencedirect.com/special-issu...
DM if interested!
Topics: RBD, circuit dysfunction, early compensatory mechanisms, chronotherapy, lifestyle interventions & more.
📅 Dec 31, 2025
🔗 www.sciencedirect.com/special-issu...
DM if interested!
#CircadianRhythms #Neuroscience #Chronotherapy #MolecularBiology @ndcnoxford.bsky.social @medsci.ox.ac.uk
August 5, 2025 at 8:52 AM
Rhythms of risk: the intersection of clocks, cancer, and chronotherapy
In this Review, Rebecca M. Mello et al. highlight the promise of integrating circadian biology into precision oncology: doi.org/10.1172/JCI1...
In this Review, Rebecca M. Mello et al. highlight the promise of integrating circadian biology into precision oncology: doi.org/10.1172/JCI1...
February 2, 2026 at 9:03 PM
Rhythms of risk: the intersection of clocks, cancer, and chronotherapy
In this Review, Rebecca M. Mello et al. highlight the promise of integrating circadian biology into precision oncology: doi.org/10.1172/JCI1...
In this Review, Rebecca M. Mello et al. highlight the promise of integrating circadian biology into precision oncology: doi.org/10.1172/JCI1...
As someone obsessed with time stories and magics in ficiton, I found the word "chronotherapy" to be one of the most badass sounding therapies I've ever heard lmaooo
(I was researching something about maximizing one's treatments via one's circadian rhythm and that word came up and I was like 👀👀👀)
(I was researching something about maximizing one's treatments via one's circadian rhythm and that word came up and I was like 👀👀👀)
November 7, 2024 at 2:00 AM
As someone obsessed with time stories and magics in ficiton, I found the word "chronotherapy" to be one of the most badass sounding therapies I've ever heard lmaooo
(I was researching something about maximizing one's treatments via one's circadian rhythm and that word came up and I was like 👀👀👀)
(I was researching something about maximizing one's treatments via one's circadian rhythm and that word came up and I was like 👀👀👀)
#Circadian attributes of #neurological and #psychiatric disorders as basis for their medication #chronotherapy
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
April 3, 2025 at 3:50 PM
#Circadian attributes of #neurological and #psychiatric disorders as basis for their medication #chronotherapy
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
LumiCycle In Vivo
actimetrics.com/products/Lum...
ClockLab Data Collection and Analysis for Circadian Biology
actimetrics.com/products/clo...
#CancerResearch #Glioblastoma #CircadianRhythms #Chronotherapy #LumiCycle #ClockLab
actimetrics.com/products/Lum...
ClockLab Data Collection and Analysis for Circadian Biology
actimetrics.com/products/clo...
#CancerResearch #Glioblastoma #CircadianRhythms #Chronotherapy #LumiCycle #ClockLab
LumiCycle In Vivo | Actimetrics
actimetrics.com
March 19, 2025 at 2:01 PM
LumiCycle In Vivo
actimetrics.com/products/Lum...
ClockLab Data Collection and Analysis for Circadian Biology
actimetrics.com/products/clo...
#CancerResearch #Glioblastoma #CircadianRhythms #Chronotherapy #LumiCycle #ClockLab
actimetrics.com/products/Lum...
ClockLab Data Collection and Analysis for Circadian Biology
actimetrics.com/products/clo...
#CancerResearch #Glioblastoma #CircadianRhythms #Chronotherapy #LumiCycle #ClockLab
🔍🤔Flip the #KYN switch to reboot immunity, metabolism & mood? 🧠🛠️We mapped cell checkpoints, chrono windows & #Probiotic+IDO/TDO combos that cut KYN & spare #KYNA🚀 @mdpiopenaccess.bsky.social #PrecisionMedicine #Microbiome #Chronotherapy 👉 Read & share! www.preprints.org/manuscript/2...
July 25, 2025 at 5:58 AM
🔍🤔Flip the #KYN switch to reboot immunity, metabolism & mood? 🧠🛠️We mapped cell checkpoints, chrono windows & #Probiotic+IDO/TDO combos that cut KYN & spare #KYNA🚀 @mdpiopenaccess.bsky.social #PrecisionMedicine #Microbiome #Chronotherapy 👉 Read & share! www.preprints.org/manuscript/2...
Immunotherapy is best administered in the morning.
Immune check point therapy
Chronotherapy
Chronobiology
www.ejcancer.com/article/S095...
Immune check point therapy
Chronotherapy
Chronobiology
www.ejcancer.com/article/S095...
Early morning immune checkpoint blockade and overall survival of patients with metastatic cancer: An In-depth chronotherapeutic study
Recent retrospective studies suggest potential large patient’s benefit through proper
timing of immune checkpoint blockers (ICB). The association between ICB treatment
timing and patient survival, neo...
www.ejcancer.com
December 9, 2025 at 9:56 AM
Immunotherapy is best administered in the morning.
Immune check point therapy
Chronotherapy
Chronobiology
www.ejcancer.com/article/S095...
Immune check point therapy
Chronotherapy
Chronobiology
www.ejcancer.com/article/S095...
Dosificación nocturna del antihipertensivo proporciona mejor control de la presión nocturna y mejora ritmo circadiano, sin reducir la eficacia en la presión arterial media diurna o en 24h ni aumentar el riesgo de hipotensión nocturna #antihypertensive #chronotherapy jamanetwork.com/journals/jam...
Morning vs Bedtime Dosing and Nocturnal Blood Pressure Reduction
This randomized clinical trial compares the effect of morning vs bedtime administration of antihypertensive agents on nocturnal blood pressure control and circadian rhythm among patients with hyperten...
jamanetwork.com
August 23, 2025 at 8:31 AM
Dosificación nocturna del antihipertensivo proporciona mejor control de la presión nocturna y mejora ritmo circadiano, sin reducir la eficacia en la presión arterial media diurna o en 24h ni aumentar el riesgo de hipotensión nocturna #antihypertensive #chronotherapy jamanetwork.com/journals/jam...
@kit maybe you could try some form of chronotherapy (e.g. get exposure to very bright full-spectrum light, e.g. from the sun or a bright light therapy panel thing, for >30min, and wear blue light blocking glasses at night)
April 6, 2025 at 2:25 AM
@kit maybe you could try some form of chronotherapy (e.g. get exposure to very bright full-spectrum light, e.g. from the sun or a bright light therapy panel thing, for >30min, and wear blue light blocking glasses at night)
Xiaoran Han: NeuroPal: A Clinically-Informed Multimodal LLM Assistant for Mental Health Combining Sleep Chronotherapy, Cognitive Behavioral Reframing, and Adaptive Phytochemical Intervention https://arxiv.org/abs/2505.06640 https://arxiv.org/pdf/2505.06640 https://arxiv.org/html/2505.06640
May 13, 2025 at 6:15 AM
Xiaoran Han: NeuroPal: A Clinically-Informed Multimodal LLM Assistant for Mental Health Combining Sleep Chronotherapy, Cognitive Behavioral Reframing, and Adaptive Phytochemical Intervention https://arxiv.org/abs/2505.06640 https://arxiv.org/pdf/2505.06640 https://arxiv.org/html/2505.06640
August 3, 2025 at 10:47 PM
Trial (720 adults, 15 hospitals) found bedtime olmesartan‑amlodipine reduced nighttime systolic BP 3 mm Hg more than morning dosing after 12 weeks, with similar safety. https://getnews.me/bedtime-dosing-improves-nighttime-blood-pressure-chinese-trial-finds/ #chronotherapy #nocturnalhypertension
October 4, 2025 at 6:23 PM
Trial (720 adults, 15 hospitals) found bedtime olmesartan‑amlodipine reduced nighttime systolic BP 3 mm Hg more than morning dosing after 12 weeks, with similar safety. https://getnews.me/bedtime-dosing-improves-nighttime-blood-pressure-chinese-trial-finds/ #chronotherapy #nocturnalhypertension
Chronotherapy in Rheumatoid Arthritis Treatment: Tantalizing but Understudied
www.medscape.com/viewarticle/...
www.medscape.com/viewarticle/...
Chronotherapy in RA Treatment: Tantalizing but Understudied
Research is evaluating chronotherapy to target drugs to reduce morning stiffness and flares in rheumatoid arthritis, but it has a long way to go before it reaches the clinic.
www.medscape.com
June 3, 2025 at 5:05 PM
Chronotherapy in Rheumatoid Arthritis Treatment: Tantalizing but Understudied
www.medscape.com/viewarticle/...
www.medscape.com/viewarticle/...
Implantable systems for neurological chronotherapy
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
April 6, 2025 at 4:02 PM
Implantable systems for neurological chronotherapy
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...