Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/4qydeE1
ja.ma/4qydeE1
December 27, 2025 at 1:00 PM
Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/4qydeE1
ja.ma/4qydeE1
From @jama.com: Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/3YB0S1E
ja.ma/3YB0S1E
December 20, 2025 at 3:00 PM
From @jama.com: Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/3YB0S1E
ja.ma/3YB0S1E
📊 Research Summary: Valacyclovir did not improve cognition or function in patients with early symptomatic #AlzheimerDisease with HSV seropositivity and is not supported for use in this population.
ja.ma/3YuB2fN
ja.ma/3YuB2fN
December 17, 2025 at 4:45 PM
📊 Research Summary: Valacyclovir did not improve cognition or function in patients with early symptomatic #AlzheimerDisease with HSV seropositivity and is not supported for use in this population.
ja.ma/3YuB2fN
ja.ma/3YuB2fN
💬 Editorial: Valacyclovir showed no benefit for cognitive outcomes in symptomatic #AlzheimerDisease, challenging the therapeutic role of antiviral agents in treating HSV-1 in #dementia.
ja.ma/3MGGxFJ
ja.ma/3MGGxFJ
December 17, 2025 at 4:30 PM
💬 Editorial: Valacyclovir showed no benefit for cognitive outcomes in symptomatic #AlzheimerDisease, challenging the therapeutic role of antiviral agents in treating HSV-1 in #dementia.
ja.ma/3MGGxFJ
ja.ma/3MGGxFJ
Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/4rYMRZe
ja.ma/4rYMRZe
December 17, 2025 at 4:15 PM
Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/4rYMRZe
ja.ma/4rYMRZe
Editorial: Plasma tau biomarkers such as p-tau217 are robust predictors of #AlzheimerDisease pathology, but their use as interchangeable substitutes for tau PET imaging may be limited, especially in the context of disease stage and anti-amyloid treatment. ja.ma/48Utzf1
December 15, 2025 at 5:00 PM
Editorial: Plasma tau biomarkers such as p-tau217 are robust predictors of #AlzheimerDisease pathology, but their use as interchangeable substitutes for tau PET imaging may be limited, especially in the context of disease stage and anti-amyloid treatment. ja.ma/48Utzf1
Individuals with #AlzheimerDisease showing greater clinical impairment than predicted by tau burden are more likely to have copathology, including #TDP43 and #AlphaSynuclein, and experience faster decline. ja.ma/3KLq5Du
December 15, 2025 at 4:30 PM
Individuals with #AlzheimerDisease showing greater clinical impairment than predicted by tau burden are more likely to have copathology, including #TDP43 and #AlphaSynuclein, and experience faster decline. ja.ma/3KLq5Du
Research suggests that #AlzheimerDisease may develop through distinct biological pathways. J. Deger, J. Shulman, H. Bellen, Z. Liu et al. @bcmhouston.bsky.social @ajhgnews.bsky.social blogs.bcm.edu/2025/12/11/f...
Research suggests that Alzheimer’s disease may develop through distinct biological pathways
This study analyzes fruit fly and human data to offer new insights into how Alzheimer’s disease risk genes affect the brain.
blogs.bcm.edu
December 11, 2025 at 5:07 PM
Research suggests that #AlzheimerDisease may develop through distinct biological pathways. J. Deger, J. Shulman, H. Bellen, Z. Liu et al. @bcmhouston.bsky.social @ajhgnews.bsky.social blogs.bcm.edu/2025/12/11/f...
Congratulations to @WashU senior Omar Abdelmoity who is one of two WashU Rhodes Scholarship finalists! Abdelmoity works with the Ances lab on the progression of #AlzheimerDisease in individuals with #DownSyndrome.
https://bit.ly/3XLJRkW
https://bit.ly/3XLJRkW
November 26, 2025 at 7:20 PM
Congratulations to @WashU senior Omar Abdelmoity who is one of two WashU Rhodes Scholarship finalists! Abdelmoity works with the Ances lab on the progression of #AlzheimerDisease in individuals with #DownSyndrome.
https://bit.ly/3XLJRkW
https://bit.ly/3XLJRkW
#MedNews - Older adults with preclinical #AlzheimerDisease could slow tau accumulation and cognitive deterioration by doing moderate levels of physical activity.
Full story 👉 buff.ly/flmgL68
#NeuroSky #Dementia
Full story 👉 buff.ly/flmgL68
#NeuroSky #Dementia
Physical activity slows tau accumulation and cognitive decline in preclinical Alzheimer disease
Older adults with preclinical Alzheimer disease could slow tau accumulation and cognitive deterioration by doing moderate levels of physical activity.
buff.ly
November 24, 2025 at 4:15 PM
#MedNews - Older adults with preclinical #AlzheimerDisease could slow tau accumulation and cognitive deterioration by doing moderate levels of physical activity.
Full story 👉 buff.ly/flmgL68
#NeuroSky #Dementia
Full story 👉 buff.ly/flmgL68
#NeuroSky #Dementia
#Neurodegenerative Theme Review: The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and #AlzheimerDisease. @bcmhouston.bsky.social
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00026-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00026-4/fulltext
The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and Alzheimer Disease
Alzheimer disease (AD) is the most common type of dementia and one of the leading
causes of death in elderly patients. The number of patients with AD in the United
States is projected to double by 2060. Thus, understanding modifiable risk factors
for AD is an urgent public health priority. In parallel with the number of patients
with AD, the number of cancer survivors is estimated to increase significantly, and
up to 80% of cancer patients treated with chemotherapy will develop cognitive defi...
ajp.amjpathol.org
November 12, 2025 at 2:43 PM
#Neurodegenerative Theme Review: The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and #AlzheimerDisease. @bcmhouston.bsky.social
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00026-4/fulltext
#OpenAccess text: https://ajp.amjpathol.org/article/S0002-9440(25)00026-4/fulltext
Disrupted #sleep is an easily detectable and modifiable risk factor for #AlzheimerDisease.
Learn how sleep metrics could become powerful tools for detection, prevention, and intervention, even before cognitive symptoms appear.
👉 buff.ly/mjCRNce
#NeuroSky
Learn how sleep metrics could become powerful tools for detection, prevention, and intervention, even before cognitive symptoms appear.
👉 buff.ly/mjCRNce
#NeuroSky
Sleep Abnormalities and Risk of Alzheimer’s Disease
Disrupted sleep is an easily detectable and modifiable risk factor for Alzheimer disease. Learn how sleep metrics could become powerful tools for detection, prevention, and intervention, even before…
buff.ly
October 30, 2025 at 11:54 AM
Disrupted #sleep is an easily detectable and modifiable risk factor for #AlzheimerDisease.
Learn how sleep metrics could become powerful tools for detection, prevention, and intervention, even before cognitive symptoms appear.
👉 buff.ly/mjCRNce
#NeuroSky
Learn how sleep metrics could become powerful tools for detection, prevention, and intervention, even before cognitive symptoms appear.
👉 buff.ly/mjCRNce
#NeuroSky
The #FDA has cleared the first blood test to rule out Alzheimer-related amyloid pathology.
Roche’s Elecsys pTau181 test detects phosphorylated Tau 181 to assess early cognitive decline #AlzheimerDisease
www.hcplive.com/view...
Roche’s Elecsys pTau181 test detects phosphorylated Tau 181 to assess early cognitive decline #AlzheimerDisease
www.hcplive.com/view...
October 14, 2025 at 11:00 PM
The #FDA has cleared the first blood test to rule out Alzheimer-related amyloid pathology.
Roche’s Elecsys pTau181 test detects phosphorylated Tau 181 to assess early cognitive decline #AlzheimerDisease
www.hcplive.com/view...
Roche’s Elecsys pTau181 test detects phosphorylated Tau 181 to assess early cognitive decline #AlzheimerDisease
www.hcplive.com/view...
An ensemble of ResNet‑50, NASNet and MobileNet reached 99.21% accuracy detecting Alzheimer’s vs mild cognitive impairment on ADNI, using Grad‑CAM heatmaps. https://getnews.me/hybrid-deep-learning-ensemble-with-explainable-ai-boosts-alzheimer-diagnosis/ #alzheimerdisease #deeplearning
October 3, 2025 at 4:31 AM
An ensemble of ResNet‑50, NASNet and MobileNet reached 99.21% accuracy detecting Alzheimer’s vs mild cognitive impairment on ADNI, using Grad‑CAM heatmaps. https://getnews.me/hybrid-deep-learning-ensemble-with-explainable-ai-boosts-alzheimer-diagnosis/ #alzheimerdisease #deeplearning
#Medsky🧪 #Neurosky #publichealth @jama.com #Alzheimerdisease is more common in women than men ,~ 2 out of every 3 people living with AD in the 🇺🇸 is a woman. Often attributed to the fact that women tend to live longer,
September 26, 2025 at 4:03 PM
#Medsky🧪 #Neurosky #publichealth @jama.com #Alzheimerdisease is more common in women than men ,~ 2 out of every 3 people living with AD in the 🇺🇸 is a woman. Often attributed to the fact that women tend to live longer,
Alzheimer disease is increasingly associated with metabolic dysfunction, particularly insulin resistance, but is the description of #AlzheimerDisease driven by metabolic disturbances as type 3 #diabetes justified?
👉 buff.ly/59ExIzo
#NeuroSky #T3D #MedSky
👉 buff.ly/59ExIzo
#NeuroSky #T3D #MedSky
A systematic review on type 3 diabetes: bridging the gap between metabolic dysfunction and Alzheimer’s disease
Alzheimer disease is increasingly associated with metabolic dysfunction, particularly insulin resistance, but is the description of Alzheimer disease driven by metabolic disturbances as type 3…
www.springermedicine.com
September 7, 2025 at 10:54 AM
Alzheimer disease is increasingly associated with metabolic dysfunction, particularly insulin resistance, but is the description of #AlzheimerDisease driven by metabolic disturbances as type 3 #diabetes justified?
👉 buff.ly/59ExIzo
#NeuroSky #T3D #MedSky
👉 buff.ly/59ExIzo
#NeuroSky #T3D #MedSky
#Epigenetics modulation of the topography of #AlzheimerDisease pathology linked to #AtypicalAD presentations doi.org/10.1016/j.ne... #Aging @alzassociation @AlzSocResearch @TheADDF #Alzheimers #Dementia #MentalHealth #Brain #TranslationalScience
Redirecting
doi.org
August 21, 2025 at 1:49 PM
#Epigenetics modulation of the topography of #AlzheimerDisease pathology linked to #AtypicalAD presentations doi.org/10.1016/j.ne... #Aging @alzassociation @AlzSocResearch @TheADDF #Alzheimers #Dementia #MentalHealth #Brain #TranslationalScience
#Transformer 3DNesT model achieved state-of-the-art accuracy in identifying #Alzheimer disease using structural MRI data https://doi.org/10.1148/ryai.240508 #AlzheimerDisease #brain #3DNesT
August 6, 2025 at 7:15 AM
#Transformer 3DNesT model achieved state-of-the-art accuracy in identifying #Alzheimer disease using structural MRI data https://doi.org/10.1148/ryai.240508 #AlzheimerDisease #brain #3DNesT
This is encouraging! An interim analysis of a Ph1b/2a study of an investigational anti-amyloid antibody drug shows promising results in #Alzheimers! And this drug is given by IV.
#AlzheimerDisease #Neurodegeneration #Antibodies #Bispecifics #Medicine
www.medpagetoday.com/meetingcover...
#AlzheimerDisease #Neurodegeneration #Antibodies #Bispecifics #Medicine
www.medpagetoday.com/meetingcover...
Novel Anti-Amyloid Drug Aims to Outperform Current Standards
Engineered to cross blood-brain barrier and scavenge plaques more effectively
www.medpagetoday.com
August 4, 2025 at 3:19 PM
This is encouraging! An interim analysis of a Ph1b/2a study of an investigational anti-amyloid antibody drug shows promising results in #Alzheimers! And this drug is given by IV.
#AlzheimerDisease #Neurodegeneration #Antibodies #Bispecifics #Medicine
www.medpagetoday.com/meetingcover...
#AlzheimerDisease #Neurodegeneration #Antibodies #Bispecifics #Medicine
www.medpagetoday.com/meetingcover...
Role of Tau-variant in #AlzheimerDisease becoming more intriguing 👇🏻
theconversation.com/babies-have-...
theconversation.com/babies-have-...
Babies have more of this Alzheimer’s-linked protein than dementia patients – study raises hope for future treatments
Scientists discover that ‘toxic’ Alzheimer’s protein is essential for baby brain development.
theconversation.com
July 19, 2025 at 9:23 AM
Role of Tau-variant in #AlzheimerDisease becoming more intriguing 👇🏻
theconversation.com/babies-have-...
theconversation.com/babies-have-...
such as #aducanumab for #Alzheimerdisease, #tofersen for ALS , #delandistrogene #moxeparvovec for #Duchennemusculardystrophy & #voxelotor for #sicklecelldisease
@jama.com
ja.ma/3GHGhDE
jamanetwork.com/journals/jam...
@jama.com
ja.ma/3GHGhDE
jamanetwork.com/journals/jam...
Regulatory and Clinical Outcomes of Nononcology Accelerated Approvals
This study uses US Food and Drug Administration (FDA) data to characterize pivotal and confirmatory trials supporting agency decision-making in the context of the FDA accelerated approval pathway for ...
jamanetwork.com
July 14, 2025 at 4:03 PM
June 12, 2025 at 5:22 PM
Ferroptosis occurs throughout the body, but a considerable research focus on ferroptosis in 🧠 #neuroferroptosis . What makes 🧠 susceptible to #ferroptosis that’s in common neurodegenerative conditions such as #Alzheimerdisease, #Parkinsondisease & ALS?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neuroferroptosis in health and diseases - Nature Reviews Neuroscience
The brain’s high lipid content, iron levels and oxygen metabolism uniquely predispose it to ferroptosis, an iron-dependent form of regulated cell death. In this Review, Lei et al. discuss brain-specif...
www.nature.com
June 3, 2025 at 5:31 PM
Ferroptosis occurs throughout the body, but a considerable research focus on ferroptosis in 🧠 #neuroferroptosis . What makes 🧠 susceptible to #ferroptosis that’s in common neurodegenerative conditions such as #Alzheimerdisease, #Parkinsondisease & ALS?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
First day off with home care. Got my hair done ahead of birthday 56 next week, spent an hour at IKEA, and am treating myself to a solo lunch. Thank God for home support. #AlzheimerDisease #Caregiving #MentalHealth
May 9, 2025 at 4:56 PM
First day off with home care. Got my hair done ahead of birthday 56 next week, spent an hour at IKEA, and am treating myself to a solo lunch. Thank God for home support. #AlzheimerDisease #Caregiving #MentalHealth