ZK
@zkfortre.bsky.social
UF MD/PhD, now Postdoc.
Neuroendocrinology/CRF/ HPA Axis/Glucocorticoids, Metabolism, Dementia models, Dopamine.
Lover of cats, dogs, backyard plants, and Diet Mountain Dew.
Neuroendocrinology/CRF/ HPA Axis/Glucocorticoids, Metabolism, Dementia models, Dopamine.
Lover of cats, dogs, backyard plants, and Diet Mountain Dew.
@sciencevs.bsky.social have enjoyed the show over the years, but I have to be honest to say I was pretty disappointed at the lack of methodological critiques of fluoride cohort studies. Even a cursory reading identify clear, significant limitations.
April 10, 2025 at 10:42 PM
@sciencevs.bsky.social have enjoyed the show over the years, but I have to be honest to say I was pretty disappointed at the lack of methodological critiques of fluoride cohort studies. Even a cursory reading identify clear, significant limitations.
Reposted by ZK
This publication in Nature was fascinating: Cancer cells swap mutated mitochondria with tumor-infiltrating immune cells (TILs). Metabolism is the keystone of cancer immunotherapy, yet often overlooked. Could this mechanism provide clues to increasing patient response? www.nature.com/articles/s41...
Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
www.nature.com
February 3, 2025 at 3:38 PM
This publication in Nature was fascinating: Cancer cells swap mutated mitochondria with tumor-infiltrating immune cells (TILs). Metabolism is the keystone of cancer immunotherapy, yet often overlooked. Could this mechanism provide clues to increasing patient response? www.nature.com/articles/s41...
Eastern markets are having none of it.
April 7, 2025 at 12:18 AM
Eastern markets are having none of it.
Were all couple hundred thousand protestors Soros plants, then? Elon? Right wing grift-o-sphere?
www.nytimes.com/2025/04/05/u...
www.nytimes.com/2025/04/05/u...
Anti-Trump Protests Get Underway Across the Country
Demonstrators packed the streets in cities and towns to rail against government cutbacks, financial turmoil and what they viewed as attacks on democracy.
www.nytimes.com
April 6, 2025 at 1:04 AM
Were all couple hundred thousand protestors Soros plants, then? Elon? Right wing grift-o-sphere?
www.nytimes.com/2025/04/05/u...
www.nytimes.com/2025/04/05/u...
Reposted by ZK
I'm proud to share ProPublica's 2024 annual report. Being transparent about our work and its impact in the world is one of the things I like most about working here. Hope you'll give this a look:
ProPublica's 2024 Annual Report
ProPublica is an independent, non-profit newsroom that produces investigative journalism in the public interest.
www.propublica.org
April 4, 2025 at 6:49 PM
I'm proud to share ProPublica's 2024 annual report. Being transparent about our work and its impact in the world is one of the things I like most about working here. Hope you'll give this a look:
Reposted by ZK
ICYMI — SENATOR BOOKER: “I rise to disrupt the business of the senate for as long as I am physically able… because I believe sincerely our country is in crisis.” 🇺🇸
April 1, 2025 at 12:09 PM
ICYMI — SENATOR BOOKER: “I rise to disrupt the business of the senate for as long as I am physically able… because I believe sincerely our country is in crisis.” 🇺🇸
Makes me wonder why I’m working on a Saturday.
March 29, 2025 at 4:32 PM
Makes me wonder why I’m working on a Saturday.
Well there it is
New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety
Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eatin...
www.science.org
March 27, 2025 at 7:02 PM
Well there it is
A transformative platform will be delayed by what? A decade? 2 decades? All because of political valence. Tragic.
Exclusive: NIH officials have advised scientists to remove reference to mRNA vaccines from their grant applications, in expectation the Trump administration intends to abandon most research in the field.
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
March 18, 2025 at 12:18 AM
A transformative platform will be delayed by what? A decade? 2 decades? All because of political valence. Tragic.
@profgalloway.com I’m not sure equating Steve Bannon to AOC is the equivalency you want to posit to make your “crossing enemy lines” point.
March 14, 2025 at 11:16 PM
@profgalloway.com I’m not sure equating Steve Bannon to AOC is the equivalency you want to posit to make your “crossing enemy lines” point.
Apparently we are aiming to take no steps forward and all the steps back.
February 25, 2025 at 7:05 AM
Apparently we are aiming to take no steps forward and all the steps back.
Honestly this is unserious on many levels.
1. DOGE has essentially been repackaged at the successor to the Obama admin’s digital asset platform.
2. This reflects such an unmitigated lack of familiarity with the NIH grant workflow that it’s clear he’s talked to no one about it.
I could go on…
1. DOGE has essentially been repackaged at the successor to the Obama admin’s digital asset platform.
2. This reflects such an unmitigated lack of familiarity with the NIH grant workflow that it’s clear he’s talked to no one about it.
I could go on…
Trump is doing what you do after you acquire a company. Crazy I know. But reality. The Dir of NIH should reach out to DOGE and offer to bring them in to remove inefficiencies.
There are always some and the Director know what they are.
DOGE gets a win. NIH gets back to work.
There are always some and the Director know what they are.
DOGE gets a win. NIH gets back to work.
Hi Mark, how do you feel about cancer research being canceled.
January 25, 2025 at 8:16 PM
Honestly this is unserious on many levels.
1. DOGE has essentially been repackaged at the successor to the Obama admin’s digital asset platform.
2. This reflects such an unmitigated lack of familiarity with the NIH grant workflow that it’s clear he’s talked to no one about it.
I could go on…
1. DOGE has essentially been repackaged at the successor to the Obama admin’s digital asset platform.
2. This reflects such an unmitigated lack of familiarity with the NIH grant workflow that it’s clear he’s talked to no one about it.
I could go on…
Reposted by ZK
One of the more absurd things that gets said in the ER a lot is that a chief complaint probably isn’t serious or real when it’s an unhoused patient.
Gonna blow some minds and point out that *people sleeping outdoors with no money are actually going to get sick more often*.
Gonna blow some minds and point out that *people sleeping outdoors with no money are actually going to get sick more often*.
December 21, 2024 at 11:49 PM
One of the more absurd things that gets said in the ER a lot is that a chief complaint probably isn’t serious or real when it’s an unhoused patient.
Gonna blow some minds and point out that *people sleeping outdoors with no money are actually going to get sick more often*.
Gonna blow some minds and point out that *people sleeping outdoors with no money are actually going to get sick more often*.
Reposted by ZK
As NYC health commissioner and CDC director, I raised alarms about the harms of unhealthy food high in salt and sugar—and fought for creative, lifesaving solutions.
Dr. Tom Farley and I write about the potential for progress and the powerful obstacles in the way.
Dr. Tom Farley and I write about the potential for progress and the powerful obstacles in the way.
Essay | We Battled Big Food. Can RFK, Jr. Succeed Where We Failed?
Two former top health officials say Kennedy can Make America Healthy Again—if he’s willing to take on soda companies, ultraprocessed foods, farm subsidies and other powerful forces that shape the way ...
www.wsj.com
November 30, 2024 at 2:17 PM
As NYC health commissioner and CDC director, I raised alarms about the harms of unhealthy food high in salt and sugar—and fought for creative, lifesaving solutions.
Dr. Tom Farley and I write about the potential for progress and the powerful obstacles in the way.
Dr. Tom Farley and I write about the potential for progress and the powerful obstacles in the way.
@dkthomp.bsky.social you had a guest today (great episode btw) state that the amyloid hypothesis was false.
This is not an accurate encapsulation whatsoever, even in the face of the fraud cases.
This is not an accurate encapsulation whatsoever, even in the face of the fraud cases.
November 27, 2024 at 4:25 PM
@dkthomp.bsky.social you had a guest today (great episode btw) state that the amyloid hypothesis was false.
This is not an accurate encapsulation whatsoever, even in the face of the fraud cases.
This is not an accurate encapsulation whatsoever, even in the face of the fraud cases.
Air feels a lot cleaner and fresher over here.
November 24, 2024 at 3:30 AM
Air feels a lot cleaner and fresher over here.