Yanín Guerra
@yaninguerra.bsky.social
Drosofishicist :)
KITP Postdoc in the Streichan group
KITP Postdoc in the Streichan group
Pinned
Yanín Guerra
@yaninguerra.bsky.social
· Jul 19
🧬 New paper alert! We used AFM PeakForce tapping to map the nanoscale topography of the basement membrane in Drosophila wing discs—revealing unexpected fiber-like and self-affine structures. #BasementMembrane #AFM
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Yanín Guerra
Axolotl can regrow lost limbs, matching their body size. How? Our new theory-experiment paper in @pnas.org proposes how oppositely oriented morphogen gradients scaling with animal size promote proportional growth. Great collaboration with @tatianasg.bsky.social @cmcb-tud.bsky.social
November 26, 2025 at 9:59 AM
Axolotl can regrow lost limbs, matching their body size. How? Our new theory-experiment paper in @pnas.org proposes how oppositely oriented morphogen gradients scaling with animal size promote proportional growth. Great collaboration with @tatianasg.bsky.social @cmcb-tud.bsky.social
Reposted by Yanín Guerra
Boris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪
Boris Shraiman points a physicist’s eye on biological quandaries
Boris Shraiman is awarded the American Physical Society’s Max Delbrück Prize in Biological Physics.
news.ucsb.edu
November 25, 2025 at 7:38 PM
Boris Shraiman points a physicist’s eye on biological quandaries news.ucsb.edu/2025/022264/... 🧪
Reposted by Yanín Guerra
Heard of the Evelyn Tables? Displays of real human nerves & blood vessels in their positions in the body. Love that @realgdt.bsky.social included these 17th century science artifacts in #Frankenstein.
Love this article by @emmalgometz.bsky.social, too! www.sciencefriday.com/articles/fra...
Love this article by @emmalgometz.bsky.social, too! www.sciencefriday.com/articles/fra...
400-Year-Old Displays Of Human Tissue Live On In ‘Frankenstein’
The 17th century Evelyn Tables show real human nerves and veins, dried on wooden boards. Designers on the new Netflix film took note.
www.sciencefriday.com
November 18, 2025 at 7:23 PM
Heard of the Evelyn Tables? Displays of real human nerves & blood vessels in their positions in the body. Love that @realgdt.bsky.social included these 17th century science artifacts in #Frankenstein.
Love this article by @emmalgometz.bsky.social, too! www.sciencefriday.com/articles/fra...
Love this article by @emmalgometz.bsky.social, too! www.sciencefriday.com/articles/fra...
Reposted by Yanín Guerra
Our next #ForceTalk is Prof Yanlan Mao @yanlanmao.bsky.social on "Coping with mechanical stress: tissue dynamics during development, homeostasis and repair"
🗓️ 26 Nov 2025
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force-talk-yanlan-mao
#mechanobiology @kingsnmes.bsky.social
🗓️ 26 Nov 2025
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force-talk-yanlan-mao
#mechanobiology @kingsnmes.bsky.social
November 18, 2025 at 5:59 PM
Our next #ForceTalk is Prof Yanlan Mao @yanlanmao.bsky.social on "Coping with mechanical stress: tissue dynamics during development, homeostasis and repair"
🗓️ 26 Nov 2025
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force-talk-yanlan-mao
#mechanobiology @kingsnmes.bsky.social
🗓️ 26 Nov 2025
🕒 15:00 - 16:00 GMT
Online & open to all 👉 www.kcl.ac.uk/events/force-talk-yanlan-mao
#mechanobiology @kingsnmes.bsky.social
Reposted by Yanín Guerra
Fiore, V. F., Almagro, J., & Fuchs, E. (2025). Shaping epithelial tissues by stem cell mechanics in development and cancer. Nature Reviews Molecular Cell Biology, doi.org/10.1038/s415... #EpithelialMechanicsReviews
November 20, 2025 at 8:01 AM
Fiore, V. F., Almagro, J., & Fuchs, E. (2025). Shaping epithelial tissues by stem cell mechanics in development and cancer. Nature Reviews Molecular Cell Biology, doi.org/10.1038/s415... #EpithelialMechanicsReviews
Reposted by Yanín Guerra
Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1.
Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
November 19, 2025 at 11:45 PM
Advanced grad students + postdocs: apply for the 2026 #kitpqbio summer course, "Physical Principles of Morphogenesis in Plants and Animals," at buff.ly/OXXMKEv. Apply by Feb. 1.
Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
Course directors Adrienne Roeder (Cornell) and Sebastian Streichan (UCSB)
Reposted by Yanín Guerra
Searching for physical principles of morphogenesis
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
November 19, 2025 at 10:28 AM
Searching for physical principles of morphogenesis
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory
doi.org/10.1242/dev....
Reposted by Yanín Guerra
Happy to share our new work from my graduate lab, with friends & colleagues @suewop.bsky.social, Pieter Derksen, Gary Han, Nikolas Claussen, and @streichan.bsky.social! We find that germ layers exhibit persistent, distinct flow patterns during zebrafish gastrulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula
During gastrulation, a sequence of complex processes transforms the blastula into a multilayered embryo. Fixed sample analysis has revealed much about how genetic signaling cascades determine the majo...
www.biorxiv.org
November 13, 2025 at 9:17 PM
Happy to share our new work from my graduate lab, with friends & colleagues @suewop.bsky.social, Pieter Derksen, Gary Han, Nikolas Claussen, and @streichan.bsky.social! We find that germ layers exhibit persistent, distinct flow patterns during zebrafish gastrulation.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Yanín Guerra
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
November 12, 2025 at 3:35 PM
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
Reposted by Yanín Guerra
Geng, @kjverhey1.bsky.social et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors rupress.org/jcb/article/...
August 11, 2025 at 5:15 PM
Geng, @kjverhey1.bsky.social et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors rupress.org/jcb/article/...
Reposted by Yanín Guerra
Best paper title?: “How to make a new nose for someone when it is off entirely and the dog has eaten it”—c.1460 von Pfalzpaint.
I talk noses: @npr.org Shortwave (Regina Barber) tinyurl.com/23dvwzmv
Video of my nightclub version @oddsalon.bsky.social
tinyurl.com/4snnacs3
#storiesmatter
(my art)
I talk noses: @npr.org Shortwave (Regina Barber) tinyurl.com/23dvwzmv
Video of my nightclub version @oddsalon.bsky.social
tinyurl.com/4snnacs3
#storiesmatter
(my art)
September 17, 2025 at 2:25 AM
Best paper title?: “How to make a new nose for someone when it is off entirely and the dog has eaten it”—c.1460 von Pfalzpaint.
I talk noses: @npr.org Shortwave (Regina Barber) tinyurl.com/23dvwzmv
Video of my nightclub version @oddsalon.bsky.social
tinyurl.com/4snnacs3
#storiesmatter
(my art)
I talk noses: @npr.org Shortwave (Regina Barber) tinyurl.com/23dvwzmv
Video of my nightclub version @oddsalon.bsky.social
tinyurl.com/4snnacs3
#storiesmatter
(my art)
Reposted by Yanín Guerra
Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics.
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...
Regulation of epithelial tissue homeostasis by active trans-epithelial transport
Epithelia are intricate tissues whose function is intimately linked to mechanics. While mechanobiology has primarily focused on factors such as cell-generated contractility and mechanical properties o...
www.biorxiv.org
September 17, 2025 at 2:46 PM
Happy to share our new study @ijmonod.bsky.social and @mpi-scienceoflight.bsky.social with C. Duclut and J. Prost. on forces generated by active fluid transport in epithelia and their role in tissue dynamics.
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...
Congrats to Huiqiong Wu, G. Arkowitz and R. Chilupuri!
www.biorxiv.org/content/10.1...
Reposted by Yanín Guerra
SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N
September 17, 2025 at 5:20 PM
SCHEPHERD--the bioelectric cell herding platform built for YOU. Single cells, monolayers, organoids--this herds them all + new tricks. Plz try it-- we will *give* you parts! Teaser here of a steering a single cell. GS Yubin Lin's lifeblood with J. Yodh on piano; Celeste R. and Paul K. Thread 1/N
Reposted by Yanín Guerra
Now #published @pnas.org: "A model for boundary-driven tissue morphogenesis", a great #biophysics #devbio collaboration led by @danielalber.bsky.social @zhaoshh.bsky.social:
doi.org/10.1073/pnas.2505160122
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
doi.org/10.1073/pnas.2505160122
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
New #preprint: "A model for boundary-driven tissue morphogenesis" arxiv.org/abs/2503.03688.
A great collaboration with @danielalber.bsky.social @zhaoshh.bsky.social, Alexandre Jacinto, Eric Wieschaus, Stas Shvartsman.
@flatironinstitute.org @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
A great collaboration with @danielalber.bsky.social @zhaoshh.bsky.social, Alexandre Jacinto, Eric Wieschaus, Stas Shvartsman.
@flatironinstitute.org @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social
September 19, 2025 at 7:52 AM
Now #published @pnas.org: "A model for boundary-driven tissue morphogenesis", a great #biophysics #devbio collaboration led by @danielalber.bsky.social @zhaoshh.bsky.social:
doi.org/10.1073/pnas.2505160122
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
doi.org/10.1073/pnas.2505160122
@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social @flatironinstitute.org
Reposted by Yanín Guerra
IG Nobel Prize in #Physics 2025 to @mpipks.bsky.social researchers for elucidating the phase behaviour of cacio e pepe sauce. The work highlights how physics can also be applied to solve daily-life problems!
nature.com/articles/d41586-025-03045-0
nature.com/articles/d41586-025-03045-0
Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research
The annual awards are a celebration of weird but thought-provoking science.
nature.com
September 19, 2025 at 1:11 PM
IG Nobel Prize in #Physics 2025 to @mpipks.bsky.social researchers for elucidating the phase behaviour of cacio e pepe sauce. The work highlights how physics can also be applied to solve daily-life problems!
nature.com/articles/d41586-025-03045-0
nature.com/articles/d41586-025-03045-0
Reposted by Yanín Guerra
Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof Carsten Grashoff now provides insight into the molecular details underlying the formation of the connections between epithelial cells. #Biology
How epithelial junctions mature: Study shows conformational transition in key protein
Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof. Carsten Grashoff now provides insight into the molecular details underlying the ...
www.uni-muenster.de
September 8, 2025 at 1:24 PM
Epithelial tissues cover the inner and outer surfaces of the body. A study by the working group of cell biologist Prof Carsten Grashoff now provides insight into the molecular details underlying the formation of the connections between epithelial cells. #Biology
Reposted by Yanín Guerra
Congratulations to postdoc Arthur Boutillon at the Campàs lab @campaslab.bsky.social for a beautiful cover image selected for the latest Development issue @dev-journal.bsky.social!
Issue 16 is complete!
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
On the cover: Embryonic eye of an anole lizard stained for nuclei and F-actin. The image was acquired at the 2025 MBL Embryology course by Arthur Boutillon and was the Editor's choice from the Node image competition.
thenode.biologists.com/vote-for-you...
September 10, 2025 at 10:38 AM
Congratulations to postdoc Arthur Boutillon at the Campàs lab @campaslab.bsky.social for a beautiful cover image selected for the latest Development issue @dev-journal.bsky.social!
First day as a KITP postdoc and a member of the Streichan group. Excited to learn some cool stuff!
September 3, 2025 at 5:11 AM
First day as a KITP postdoc and a member of the Streichan group. Excited to learn some cool stuff!
Reposted by Yanín Guerra
Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
The actin cortex acts as a mechanical memory of morphology in confined migrating cells - Nature Physics
Cells often navigate through confined spaces. Now it is shown that cells retain a mechanical memory of previous confinement events, which makes them more efficient at migrating through narrow microenv...
www.nature.com
August 25, 2025 at 9:59 AM
Excited to share our new publication in Nature Physics about the mechanical memory of morphology in confined migrating cells by @kyohalie.bsky.social 🥳
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Super fun collab with @davidbrueckner.bsky.social and @gcharras.bsky.social 👏🏻
Enjoy the reading www.nature.com/articles/s41...
Reposted by Yanín Guerra
Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data"
A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making
Applied to ventral neural tube development
www.biorxiv.org/content/10.1...
A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making
Applied to ventral neural tube development
www.biorxiv.org/content/10.1...
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Building a mechanistic understanding of cell fate decisions remains a fundamental goal of developmental biology, with implications for stem cell therapies, regenerative medicine and understanding dise...
www.biorxiv.org
May 29, 2025 at 12:08 PM
Our latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data"
A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making
Applied to ventral neural tube development
www.biorxiv.org/content/10.1...
A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making
Applied to ventral neural tube development
www.biorxiv.org/content/10.1...
Reposted by Yanín Guerra
Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...
August 27, 2025 at 12:33 PM
Supracellular control and coordination of tissue morphogenesis, through supracellular actomyosin assemblies, that is what my lab @cellbiol-mrclmb.bsky.social @pdncambridge.bsky.social and I like to dig into at the moment! Fascinating and beautiful! journals.biologists.com/dev/article/...
Reposted by Yanín Guerra
One the best things about a life in science is that your heroes often become your friends. My entire career stems from two papers by Ray Keller and I'm just thrilled to have a new piece out with Rob Huebner highlighting those classic papers.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Quantifying convergent extension: Shih and Keller's quintessential work in developmental cell biology
Few biological fields have become more intertwined in recent years than cell and developmental biology, a fact made clear by the departments of cell a…
www.sciencedirect.com
July 19, 2025 at 3:47 PM
One the best things about a life in science is that your heroes often become your friends. My entire career stems from two papers by Ray Keller and I'm just thrilled to have a new piece out with Rob Huebner highlighting those classic papers.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
🧬 New paper alert! We used AFM PeakForce tapping to map the nanoscale topography of the basement membrane in Drosophila wing discs—revealing unexpected fiber-like and self-affine structures. #BasementMembrane #AFM
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
July 19, 2025 at 9:12 AM
🧬 New paper alert! We used AFM PeakForce tapping to map the nanoscale topography of the basement membrane in Drosophila wing discs—revealing unexpected fiber-like and self-affine structures. #BasementMembrane #AFM
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Yanín Guerra
Tagging @mpi-cbg.de @poldresden.bsky.social
⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...
Morphogen gradients are regulated by porous media characteristics of the developing tissue
Summary: Image-based 3D modeling of pore-scale extracellular space geometries of the developing zebrafish embryo reveals that the Fgf8a morphogen gradient is regulated by the porous media characterist...
journals.biologists.com
July 14, 2025 at 5:00 PM
Tagging @mpi-cbg.de @poldresden.bsky.social
Reposted by Yanín Guerra
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
July 15, 2025 at 2:12 PM
🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social