@weizhangvvv.bsky.social
Reposted
A recently discovered brain network that links cognition (thinking) and actions may have an important role in Parkinson’s disease and could improve its treatment, according to a study published in Nature: spklr.io/63320DMwOi
#Neuroscience #Neuroskyence #Parkinsons 🧠 🧪
#Neuroscience #Neuroskyence #Parkinsons 🧠 🧪
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
spklr.io
February 4, 2026 at 8:11 PM
A recently discovered brain network that links cognition (thinking) and actions may have an important role in Parkinson’s disease and could improve its treatment, according to a study published in Nature: spklr.io/63320DMwOi
#Neuroscience #Neuroskyence #Parkinsons 🧠 🧪
#Neuroscience #Neuroskyence #Parkinsons 🧠 🧪
Reposted
Game-changer for PD therapy! Our @Nature study shows targeting the SCAN network with non-invasive brain stimulation doubles efficacy—no surgery needed.
#Therapy #BrainScience #HealthTech
nature.com/articles/s41...
#Therapy #BrainScience #HealthTech
nature.com/articles/s41...
February 6, 2026 at 8:39 AM
Game-changer for PD therapy! Our @Nature study shows targeting the SCAN network with non-invasive brain stimulation doubles efficacy—no surgery needed.
#Therapy #BrainScience #HealthTech
nature.com/articles/s41...
#Therapy #BrainScience #HealthTech
nature.com/articles/s41...
Reposted
(4/4) Open datasets for PD and ET are still scarce, and we hope these resources will help advance research in the community.🧠🥳
February 10, 2026 at 1:56 AM
(4/4) Open datasets for PD and ET are still scarce, and we hope these resources will help advance research in the community.🧠🥳
Reposted
(3/4) PIET includes 45 essential tremor patients, also with 30-minute scans. Download link: doi.org/10.57760/sci...
Precision Imaging Essential Tremor (PIET) dataset
Dataset description:Participants. A total of 45 ET patients (mean age = 62.02 ± 13.10 years, 15 females) were recruited from HPPH, China. The inclusion criteria included being aged 22 years or above ...
doi.org
February 10, 2026 at 1:56 AM
(3/4) PIET includes 45 essential tremor patients, also with 30-minute scans. Download link: doi.org/10.57760/sci...
Reposted
(2/4) PIPD includes 166 Parkinson’s disease patients and 60 healthy controls, each with ~30 minutes of rsfMRI data under strict motion control. Download link: doi.org/10.57760/sci...
Precision Imaging Parkinson's disease (PIPD) dataset
Dataset description:Patients. A total of 180 PD patients were recruited from Henan Provincial People’s Hospital (HPPH), China. The inclusion criteria included being aged 18 years or above and a clinic...
doi.org
February 10, 2026 at 1:56 AM
(2/4) PIPD includes 166 Parkinson’s disease patients and 60 healthy controls, each with ~30 minutes of rsfMRI data under strict motion control. Download link: doi.org/10.57760/sci...
Reposted
In case this important point gets overlooked: along with our Nature paper, we’ve publicly released two large and scarce datasets—PIPD and PIET. IMHO, these are the best open Parkinson's and Tremor datasets available to date.
See threads (1/4) 👇
nature.com/articles/s41...
See threads (1/4) 👇
nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
nature.com
February 10, 2026 at 1:56 AM
In case this important point gets overlooked: along with our Nature paper, we’ve publicly released two large and scarce datasets—PIPD and PIET. IMHO, these are the best open Parkinson's and Tremor datasets available to date.
See threads (1/4) 👇
nature.com/articles/s41...
See threads (1/4) 👇
nature.com/articles/s41...
Reposted
Parkinson's disease affects over 10 million people worldwide. A new study led by WashU Medicine researchers is paving the way for more personalized, non-invasive treatment, tackling this neurological disorder at its root. @ndosenbach.bsky.social medicine.washu.edu/news/brain-n...
Brain network responsible for Parkinson’s disease identified | WashU Medicine
In a new study, treatments targeted to the network resulted in greater improvements in symptoms compared to treating nearby brain regions.
medicine.washu.edu
February 5, 2026 at 3:34 PM
Parkinson's disease affects over 10 million people worldwide. A new study led by WashU Medicine researchers is paving the way for more personalized, non-invasive treatment, tackling this neurological disorder at its root. @ndosenbach.bsky.social medicine.washu.edu/news/brain-n...
Reposted
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies.
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
February 5, 2026 at 12:35 AM
It’s time to rethink Parkinson’s disease. Our work reframes PD as a disorder of the somato-cognitive action network (SCAN), and shows that normalizing SCAN connectivity represents a shared mechanism across diverse effective therapies.
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
rdcu.be/e2n4t
@ndosenbach.bsky.social @gordonneuro.bsky.social
Reposted
#Medsky🧪 #IDsky #Neurosky #publichealth @nature.com This study has redefined #ParkinsonsDisease (PD) as a disorder of the Somato-Cognitive Action Network (SCAN), a brain system that integrates whole-body movement, cognition, and internal physiological states
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
www.nature.com
February 7, 2026 at 5:42 AM
#Medsky🧪 #IDsky #Neurosky #publichealth @nature.com This study has redefined #ParkinsonsDisease (PD) as a disorder of the Somato-Cognitive Action Network (SCAN), a brain system that integrates whole-body movement, cognition, and internal physiological states
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...
February 8, 2026 at 4:16 AM
Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...
Reposted
Scientists discover brain network that may cause Parkinson’s disease. Via @scientific_american #MedicalScience 💉💊🏥🩸😷 #neurology
Scientists discover brain network that may cause Parkinson’s disease
An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all
www.scientificamerican.com
February 7, 2026 at 7:20 AM
Scientists discover brain network that may cause Parkinson’s disease. Via @scientific_american #MedicalScience 💉💊🏥🩸😷 #neurology
Reposted
Targeting the somato-cognitive action network (SCAN) rather than motor regions doubles efficacy of TMS treatments for Parkinson’s disease. Seems that various DBS targets for Parkinson’s are selectively connected to the SCAN rather than effector-specific motor regions.🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
www.nature.com
February 7, 2026 at 7:38 AM
Targeting the somato-cognitive action network (SCAN) rather than motor regions doubles efficacy of TMS treatments for Parkinson’s disease. Seems that various DBS targets for Parkinson’s are selectively connected to the SCAN rather than effector-specific motor regions.🧪
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
The highlight of my week was the publication of "Parkinson’s disease as a somato-cognitive action network disorder" in @nature.com. It's a great paper that shows how conceptual changes in fundamental neuroscience - the discovery of SCAN - can improve treatment 🧪 www.nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
www.nature.com
February 7, 2026 at 3:14 PM
The highlight of my week was the publication of "Parkinson’s disease as a somato-cognitive action network disorder" in @nature.com. It's a great paper that shows how conceptual changes in fundamental neuroscience - the discovery of SCAN - can improve treatment 🧪 www.nature.com/articles/s41...
Reposted
This is a nice animation illustrating the key points in the Parkinson's SCAN paper about which I posted previously.
Happy to share a short but super cool video that gives a quick overview of our Nature paper on the somato-cognitive action of netwokr in Parkinson's disease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 6, 2026 at 10:10 PM
This is a nice animation illustrating the key points in the Parkinson's SCAN paper about which I posted previously.
Reposted
Parkinson’s disease as a somato-cognitive action network disorder
https://www.newsbeep.com/385135/
Participants In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets…
https://www.newsbeep.com/385135/
Participants In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets…
Parkinson’s disease as a somato-cognitive action network disorder - News Beep
Participants
www.newsbeep.com
February 4, 2026 at 11:35 PM
Parkinson’s disease as a somato-cognitive action network disorder
https://www.newsbeep.com/385135/
Participants In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets…
https://www.newsbeep.com/385135/
Participants In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets…
Reposted
Mapping the brain's core circuit: Chinese scientists identify key to Parkinson's treatment
news.cgtn.com/news/2026-02...
news.cgtn.com/news/2026-02...
Mapping the brain's core circuit: Chinese scientists identify key to Parkinson's treatment
Chinese scientists have identified a critical neural circuit that serves as the
news.cgtn.com
February 5, 2026 at 9:17 AM
Mapping the brain's core circuit: Chinese scientists identify key to Parkinson's treatment
news.cgtn.com/news/2026-02...
news.cgtn.com/news/2026-02...
Reposted
"Brain stimulation treatments for Parkinson’s were more effective when doctors specifically targeted SCAN regions, Liu’s team also found. This experiment involved a noninvasive technique called transcranial magnetic simulation"
Scientists discover brain network that may cause Parkinson’s disease
An “extraordinary” brain network discovery shows that Parkinson’s disease may not be a movement disorder after all
www.scientificamerican.com
February 5, 2026 at 4:46 AM
"Brain stimulation treatments for Parkinson’s were more effective when doctors specifically targeted SCAN regions, Liu’s team also found. This experiment involved a noninvasive technique called transcranial magnetic simulation"
Reposted
Scientists just discovered a key brain network affected by Parkinson’s disease. The finding could change how doctors understand symptoms and lead to better treatments. 🧠 bit.ly/4qdpLMf
February 4, 2026 at 8:13 PM
Scientists just discovered a key brain network affected by Parkinson’s disease. The finding could change how doctors understand symptoms and lead to better treatments. 🧠 bit.ly/4qdpLMf
Reposted
Really cool attempt to link together multiple neuromodulation methods (DBS, TMS, TUS) to understand the neural basis of Parkinson's disease.
A recently discovered brain network that links cognition and actions may have an important role in Parkinson’s disease and could improve its treatment, according to a study in Nature. go.nature.com/49VBuKI #Neuroskyence 🧪
February 5, 2026 at 12:19 PM
Really cool attempt to link together multiple neuromodulation methods (DBS, TMS, TUS) to understand the neural basis of Parkinson's disease.
Reposted
www.nature.com/articles/s41... the original research article ... no paywall
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
www.nature.com
February 4, 2026 at 8:19 PM
www.nature.com/articles/s41... the original research article ... no paywall
Reposted
Reposted
Reposted
Non-invasive brain surface stimulation targeting personalized SCAN alleviated symptoms in patients with Parkinson’s disease. See the videos below.(www.nature.com/articles/s41...)
February 5, 2026 at 2:08 AM
Non-invasive brain surface stimulation targeting personalized SCAN alleviated symptoms in patients with Parkinson’s disease. See the videos below.(www.nature.com/articles/s41...)
Reposted
Happy to share a short but super cool video that gives a quick overview of our Nature paper on the somato-cognitive action of netwokr in Parkinson's disease
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 5, 2026 at 1:22 PM
Happy to share a short but super cool video that gives a quick overview of our Nature paper on the somato-cognitive action of netwokr in Parkinson's disease
www.nature.com/articles/s41...
www.nature.com/articles/s41...