Nico Dosenbach
@ndosenbach.bsky.social
David M. & Tracy S. Holtzman Professor, Neurology @ WashU School of Medicine; precision neuroimaging, network plasticity, BWAS ≠ fMRI, action mode; #neuroscience #neurology #openscience #science
dosenbachlab.wustl.edu
dosenbachlab.wustl.edu
Reposted by Nico Dosenbach
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory. n.pr/4kpKWtv
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
n.pr
February 10, 2026 at 11:03 AM
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory. n.pr/4kpKWtv
Reposted by Nico Dosenbach
After a year of RFK, Jr., heading the Department of Health and Human Services, the “Make America Healthy Again” movement has upended science and medicine
Here's how a year of RFK, Jr., has changed American science
After a year of RFK, Jr., heading the Department of Health and Human Services, the “Make America Healthy Again” movement has upended science and medicine
www.scientificamerican.com
February 13, 2026 at 3:53 PM
After a year of RFK, Jr., heading the Department of Health and Human Services, the “Make America Healthy Again” movement has upended science and medicine
Reposted by Nico Dosenbach
@jcooperman.bsky.social proves essay writing is *not* a lost art in her engaging, in-depth write-up of our latest research on stimulant drugs. I highly recommend her journalism, and you can find the science published in the journal Cell.
commonreader.wustl.edu/adhd-and-rit...
doi.org/10.1016/j.ce...
commonreader.wustl.edu/adhd-and-rit...
doi.org/10.1016/j.ce...
Ritalin Works-But Not the Way We Thought - Common Reader
ADHD, sleep deprivation, amphetamines and the truth of why they work
commonreader.wustl.edu
February 12, 2026 at 11:53 PM
@jcooperman.bsky.social proves essay writing is *not* a lost art in her engaging, in-depth write-up of our latest research on stimulant drugs. I highly recommend her journalism, and you can find the science published in the journal Cell.
commonreader.wustl.edu/adhd-and-rit...
doi.org/10.1016/j.ce...
commonreader.wustl.edu/adhd-and-rit...
doi.org/10.1016/j.ce...
Reposted by Nico Dosenbach
Today's anti-science pairing
February 13, 2026 at 3:10 PM
Today's anti-science pairing
Reposted by Nico Dosenbach
Scientists are increasingly turning to AI chatbots for help drafting the grant proposals that fund their careers.
Preliminary data indicate that these tools are linked with a slightly higher funding rate and might be pulling the focus of research towards safe, less-innovative ideas.
Preliminary data indicate that these tools are linked with a slightly higher funding rate and might be pulling the focus of research towards safe, less-innovative ideas.
AI help in grant proposals tied to higher funding odds at NIH
But funding proposals to US agencies also tend to be more similar to previously funded projects if they are written or edited with the help of a chatbot.
www.nature.com
February 12, 2026 at 10:05 PM
Scientists are increasingly turning to AI chatbots for help drafting the grant proposals that fund their careers.
Preliminary data indicate that these tools are linked with a slightly higher funding rate and might be pulling the focus of research towards safe, less-innovative ideas.
Preliminary data indicate that these tools are linked with a slightly higher funding rate and might be pulling the focus of research towards safe, less-innovative ideas.
Reposted by Nico Dosenbach
NEW: Another NIH institute director hasn't been renewed — the director of NIAMS (arthritis, musculoskeletal and skin diseases institute).
That leaves a whopping 15 of 27 institutes and centers without a permanent director.
That leaves a whopping 15 of 27 institutes and centers without a permanent director.
February 12, 2026 at 5:16 PM
NEW: Another NIH institute director hasn't been renewed — the director of NIAMS (arthritis, musculoskeletal and skin diseases institute).
That leaves a whopping 15 of 27 institutes and centers without a permanent director.
That leaves a whopping 15 of 27 institutes and centers without a permanent director.
Reposted by Nico Dosenbach
Objective Quality Assessment for Precision Functional MRI Data | bioRxiv www.biorxiv.org/content/10.6...
February 13, 2026 at 1:10 AM
Objective Quality Assessment for Precision Functional MRI Data | bioRxiv www.biorxiv.org/content/10.6...
Reposted by Nico Dosenbach
"The meta-skill is learning to continuously spot the next evolution and position yourself at the edge of what’s newly possible." That sounds really tiring. newsletter.jantegze.com/p/your-job-i...
Your Job Isn't Disappearing. It's Shrinking Around You in Real Time
AI isn't taking your job. It's making your expertise worthless while you watch. The three things everyone tries that fail, and the one strategy that actually works.
newsletter.jantegze.com
February 13, 2026 at 1:13 AM
"The meta-skill is learning to continuously spot the next evolution and position yourself at the edge of what’s newly possible." That sounds really tiring. newsletter.jantegze.com/p/your-job-i...
Reposted by Nico Dosenbach
Ritalin doesn't hit the attention centers after all--and it might help prevent dementia--and ADHD is a continuum for all of us--but sometimes it's misdiagnosed sleep-deprivation... One big study can reveal a lot. (AUDIO 8m) commonreader.wustl.edu/adhd-and-rit...
Ritalin Works-But Not the Way We Thought - Common Reader
ADHD, sleep deprivation, amphetamines and the truth of why they work
commonreader.wustl.edu
February 11, 2026 at 3:55 PM
Ritalin doesn't hit the attention centers after all--and it might help prevent dementia--and ADHD is a continuum for all of us--but sometimes it's misdiagnosed sleep-deprivation... One big study can reveal a lot. (AUDIO 8m) commonreader.wustl.edu/adhd-and-rit...
Reposted by Nico Dosenbach
Brain network dysfunction central to Parkinson’s disease identified
https://www.newsbeep.com/nz/279712/
Researchers led by Beijing”s Changping Laboratory have identified a specific brain network whose dysfunction appears central to Parkinson’s…
https://www.newsbeep.com/nz/279712/
Researchers led by Beijing”s Changping Laboratory have identified a specific brain network whose dysfunction appears central to Parkinson’s…
Brain network dysfunction central to Parkinson's disease identified - New Zealand News Beep
Researchers led by Beijing"s Changping Laboratory have identified a specific brain network whose dysfunction appears central to Parkinson's disease, a finding
www.newsbeep.com
February 12, 2026 at 3:00 AM
Brain network dysfunction central to Parkinson’s disease identified
https://www.newsbeep.com/nz/279712/
Researchers led by Beijing”s Changping Laboratory have identified a specific brain network whose dysfunction appears central to Parkinson’s…
https://www.newsbeep.com/nz/279712/
Researchers led by Beijing”s Changping Laboratory have identified a specific brain network whose dysfunction appears central to Parkinson’s…
Reposted by Nico Dosenbach
📰 Parkinson's May Emerge From a Deeper Brain Network Than We Thought
Targeting it vastly improved treatments.
Targeting it vastly improved treatments.
Parkinson's May Emerge From a Deeper Brain Network Than We Thought
Targeting it vastly improved treatments.
www.sciencealert.com
February 12, 2026 at 11:11 AM
📰 Parkinson's May Emerge From a Deeper Brain Network Than We Thought
Targeting it vastly improved treatments.
Targeting it vastly improved treatments.
Reposted by Nico Dosenbach
Parkinson's May Emerge From a Deeper Brain Network Than We Thought. Via @sciencealert #MedicalScience 💉💊🏥🩸😷
Parkinson's May Emerge From a Deeper Brain Network Than We Thought
A recently discovered brain network may be the core circuit underlying symptoms of Parkinson's disease.
www.sciencealert.com
February 12, 2026 at 12:20 PM
Parkinson's May Emerge From a Deeper Brain Network Than We Thought. Via @sciencealert #MedicalScience 💉💊🏥🩸😷
Reposted by Nico Dosenbach
Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...
February 8, 2026 at 4:16 AM
Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...
Reposted by Nico Dosenbach
Don’t miss out reading about this amazing work linking the SCAN to Parkinson’s disease. What are the best ways we could use this new knowledge?!
Breakthrough @nature.com study showcases new non-invasive treatment for Parkinson’s Disease that targets the somato-cognitive action network (SCAN) with personalized neuromodulation, for superior outcomes. www.nature.com/articles/s41...
February 10, 2026 at 5:03 PM
Don’t miss out reading about this amazing work linking the SCAN to Parkinson’s disease. What are the best ways we could use this new knowledge?!
Reposted by Nico Dosenbach
This complex brain network may explain many of Parkinson's stranger symptoms https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network?utm_source=dlvr.it&utm_medium=mastodon
February 10, 2026 at 11:12 AM
This complex brain network may explain many of Parkinson's stranger symptoms https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network?utm_source=dlvr.it&utm_medium=mastodon
Reposted by Nico Dosenbach
📢 Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
This complex brain network may explain many of Parkinson's stranger symptoms
www.npr.org
February 10, 2026 at 11:16 AM
Reposted by Nico Dosenbach
This complex brain network may explain many of Parkinson's stranger symptoms #Science #HealthandMedicine #Neurology #ParkinsonsDisease #Neuroscience #BrainResearch
https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network
https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
www.npr.org
February 10, 2026 at 11:44 AM
This complex brain network may explain many of Parkinson's stranger symptoms #Science #HealthandMedicine #Neurology #ParkinsonsDisease #Neuroscience #BrainResearch
https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network
https://www.npr.org/2026/02/10/nx-s1-5702451/parkinsons-disease-symptoms-scan-network
Reposted by Nico Dosenbach
This complex brain network may explain many of Parkinson's stranger symptoms www.npr.org/2026/02/10/n...
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
www.npr.org
February 10, 2026 at 6:09 PM
This complex brain network may explain many of Parkinson's stranger symptoms www.npr.org/2026/02/10/n...
Reposted by Nico Dosenbach
#ResearchSky Parkinson’s affects movement, sleep, and thinking, and current treatments can’t stop it.
A new study led by WashU pinpoints the brain network underlying the disease and shows that targeting it can dramatically improve symptoms without surgery. https://bit.ly/4tpIjfh
A new study led by WashU pinpoints the brain network underlying the disease and shows that targeting it can dramatically improve symptoms without surgery. https://bit.ly/4tpIjfh
Brain network responsible for Parkinson's disease identified
A brain network first identified by Washington University in St. Louis School of Medicine researchers, called SCAN, is shown in a new study to be the neurological basis for Parkinson's disease. Patients receiving treatments targeted to this brain region...
bit.ly
February 10, 2026 at 6:23 PM
#ResearchSky Parkinson’s affects movement, sleep, and thinking, and current treatments can’t stop it.
A new study led by WashU pinpoints the brain network underlying the disease and shows that targeting it can dramatically improve symptoms without surgery. https://bit.ly/4tpIjfh
A new study led by WashU pinpoints the brain network underlying the disease and shows that targeting it can dramatically improve symptoms without surgery. https://bit.ly/4tpIjfh
Reposted by Nico Dosenbach
More excellent reporting by NPR's Jon Hamilton about a new brain network that explains symptoms of Parkinson's that have befuddled brain researchers for decades. Kudos to @jianxunren.bsky.social and Hesheng Liu for this groundbreaking research in the journal Nature! doi.org/10.1038/s415...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
doi.org
February 10, 2026 at 6:32 PM
More excellent reporting by NPR's Jon Hamilton about a new brain network that explains symptoms of Parkinson's that have befuddled brain researchers for decades. Kudos to @jianxunren.bsky.social and Hesheng Liu for this groundbreaking research in the journal Nature! doi.org/10.1038/s415...
Reposted by Nico Dosenbach
Parkinson's is what an *actual* dopamine fast looks like: it's caused by degeneration of dopamine cells involved in motivation and movement. Also why antipsychotic drugs that block dopamine can cause Parkinsonism. Reducing pleasurable activity doesn't cut dopamine; it doesn't work that way.
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory. n.pr/4kpKWtv
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
n.pr
February 10, 2026 at 6:38 PM
Parkinson's is what an *actual* dopamine fast looks like: it's caused by degeneration of dopamine cells involved in motivation and movement. Also why antipsychotic drugs that block dopamine can cause Parkinsonism. Reducing pleasurable activity doesn't cut dopamine; it doesn't work that way.
Reposted by Nico Dosenbach
Big news for Parkinson's disease from the world of brain circuit science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
www.nature.com
February 11, 2026 at 1:27 PM
Big news for Parkinson's disease from the world of brain circuit science.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nico Dosenbach
In case this important point gets overlooked: along with our Nature paper, we’ve publicly released two large and scarce datasets—PIPD and PIET. IMHO, these are the best open Parkinson's and Tremor datasets available to date.
See threads (1/4) 👇
nature.com/articles/s41...
See threads (1/4) 👇
nature.com/articles/s41...
Parkinson’s disease as a somato-cognitive action network disorder - Nature
The substantia nigra and all Parkinson’s disease deep-brain stimulation targets are selectively connected to the somato-cognitive action network rather than to effector-specific motor regions.
nature.com
February 10, 2026 at 1:56 AM
In case this important point gets overlooked: along with our Nature paper, we’ve publicly released two large and scarce datasets—PIPD and PIET. IMHO, these are the best open Parkinson's and Tremor datasets available to date.
See threads (1/4) 👇
nature.com/articles/s41...
See threads (1/4) 👇
nature.com/articles/s41...
Reposted by Nico Dosenbach
This complex brain network may explain many of Parkinson’s stranger symptoms
www.npr.org/2026/02/10/n...
www.npr.org/2026/02/10/n...
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
www.npr.org
February 10, 2026 at 7:45 PM
This complex brain network may explain many of Parkinson’s stranger symptoms
www.npr.org/2026/02/10/n...
www.npr.org/2026/02/10/n...
Reposted by Nico Dosenbach
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
This complex brain network may explain many of Parkinson's stranger symptoms
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.
buff.ly
February 10, 2026 at 10:45 PM
Parkinson's disease appears to disrupt a brain network involved in everything from movement to memory.