Victor Dubach
@vicsnor.bsky.social
PhD student @bjmurphylab.bsky.social @mpibp.bsky.social with @imprs-cbp.bsky.social
Interested in #cryoEM 🔬❄️, redox and membrane proteins
Interested in #cryoEM 🔬❄️, redox and membrane proteins
Reposted by Victor Dubach
Yesterday I finally defended my PhD thesis - time to say thank you to all those who were part of this journey as mentors, collaborators, colleagues and friends!
November 7, 2025 at 3:49 PM
Yesterday I finally defended my PhD thesis - time to say thank you to all those who were part of this journey as mentors, collaborators, colleagues and friends!
Reposted by Victor Dubach
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
November 6, 2025 at 7:38 AM
Just published! We share an open-source workflow to measure membrane thickness from tomograms, including a tutorial with 3D visualizations. We analyze thickness variations across organelles and reflect on where to define a membrane boundary. @becklab.bsky.social #teamtomo rupress.org/jcb/article/...
Reposted by Victor Dubach
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
November 5, 2025 at 12:12 PM
Exciting week in Frankfurt! Our CEOS energy filter and ASI Timepix3 are installed and we're looking forward to running the first tests :) #CryoEM #timepix #REELanalysis #4DSTEM @mpibp.bsky.social
Reposted by Victor Dubach
Our first lab paper is out! We identify and solve the first structure of the SND3 translocon involved in fungal membrane protein insertion. Congratulations @tzujingyang.bsky.social, and our colleagues @saumyakm.bsky.social, @hummerlab.bsky.social and Julian Langer. Read more ⬇️ and ➡️ rdcu.be/eNgIO
SNDing proteins into the membrane! Our new publication from @melaniemcdowell.bsky.social ’s group identifies the SND3 protein as a new route for membrane protein insertion! 🍄 📘 Read more here: www.mpg.de/25599408/102... Image: Louise Duever.
October 30, 2025 at 5:42 PM
Our first lab paper is out! We identify and solve the first structure of the SND3 translocon involved in fungal membrane protein insertion. Congratulations @tzujingyang.bsky.social, and our colleagues @saumyakm.bsky.social, @hummerlab.bsky.social and Julian Langer. Read more ⬇️ and ➡️ rdcu.be/eNgIO
Reposted by Victor Dubach
SNDing proteins into the membrane! Our new publication from @melaniemcdowell.bsky.social ’s group identifies the SND3 protein as a new route for membrane protein insertion! 🍄 📘 Read more here: www.mpg.de/25599408/102... Image: Louise Duever.
October 30, 2025 at 8:55 AM
SNDing proteins into the membrane! Our new publication from @melaniemcdowell.bsky.social ’s group identifies the SND3 protein as a new route for membrane protein insertion! 🍄 📘 Read more here: www.mpg.de/25599408/102... Image: Louise Duever.
Reposted by Victor Dubach
Heartfelt congratulations to @ralfsteinhilper.bsky.social @bjmurphylab.bsky.social on successfully defending his PhD thesis with summa cum laude! 👏💪🏆 For his doctoral research, Ralf used anaerobic sample preparation to study redox enzymes by single-particle cryo-EM.🔬 #phdlife #biophysics #excellence
October 16, 2025 at 12:51 PM
Heartfelt congratulations to @ralfsteinhilper.bsky.social @bjmurphylab.bsky.social on successfully defending his PhD thesis with summa cum laude! 👏💪🏆 For his doctoral research, Ralf used anaerobic sample preparation to study redox enzymes by single-particle cryo-EM.🔬 #phdlife #biophysics #excellence
Reposted by Victor Dubach
Big thanks to everyone at @bjmurphylab.bsky.social and @mpibp.bsky.social for your support and for making this such an unforgettable time!
Heartfelt congratulations to @ralfsteinhilper.bsky.social @bjmurphylab.bsky.social on successfully defending his PhD thesis with summa cum laude! 👏💪🏆 For his doctoral research, Ralf used anaerobic sample preparation to study redox enzymes by single-particle cryo-EM.🔬 #phdlife #biophysics #excellence
October 16, 2025 at 8:10 PM
Big thanks to everyone at @bjmurphylab.bsky.social and @mpibp.bsky.social for your support and for making this such an unforgettable time!
Reposted by Victor Dubach
Our yearly retreat brought together our PhD students 👩🔬from Frankfurt and Mainz for a journey of science and community building in the mountains of Switzerland! 🏔️ #gradschool #imprs_cbp
Photos: Vinay Singh
Photos: Vinay Singh
October 13, 2025 at 9:48 AM
Our yearly retreat brought together our PhD students 👩🔬from Frankfurt and Mainz for a journey of science and community building in the mountains of Switzerland! 🏔️ #gradschool #imprs_cbp
Photos: Vinay Singh
Photos: Vinay Singh
Reposted by Victor Dubach
❓What if you could peek between your tilt series ❓ We are proud to introduce cryoTIGER -- deep-learning based tilt interpolation for enhanced reconstruction in cryo-ET. A great collaboration between Turoňová lab, @becklab.bsky.social, @hummerlab.bsky.social #teamtomo www.nature.com/articles/s42...
cryoTIGER: deep-learning based tilt interpolation generator for enhanced reconstruction in cryo electron tomography - Communications Biology
Deep learning-based interpolation using cryoTIGER enhances angular sampling in cryoET, improving 3D reconstructions, particle localization, and structural recovery without increasing electron dose.
www.nature.com
October 10, 2025 at 10:35 AM
❓What if you could peek between your tilt series ❓ We are proud to introduce cryoTIGER -- deep-learning based tilt interpolation for enhanced reconstruction in cryo-ET. A great collaboration between Turoňová lab, @becklab.bsky.social, @hummerlab.bsky.social #teamtomo www.nature.com/articles/s42...
Reposted by Victor Dubach
🎉 Congratulations to our postdoc @sergiocruzleon.bsky.social for receiving the 2026 Theory & Computation Postdoctoral Research Award from the Biophysical Society! 🎉 Sergio will present his work at the Theory & Computation subgroup Symposium during the 2026 Biophysical Society meeting.
September 29, 2025 at 2:25 PM
🎉 Congratulations to our postdoc @sergiocruzleon.bsky.social for receiving the 2026 Theory & Computation Postdoctoral Research Award from the Biophysical Society! 🎉 Sergio will present his work at the Theory & Computation subgroup Symposium during the 2026 Biophysical Society meeting.
Reposted by Victor Dubach
🔬 Check out our new article on the mitochondrial TOM complex! Researchers from the Structural Biology Department have resolved a high-resolution structure of the main entry point for proteins into mitochondria. 🚪 🤩
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Visualizing the Main Gate into Mitochondria
www.biophys.mpg.de
July 21, 2025 at 3:23 PM
🔬 Check out our new article on the mitochondrial TOM complex! Researchers from the Structural Biology Department have resolved a high-resolution structure of the main entry point for proteins into mitochondria. 🚪 🤩
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Read more: www.biophys.mpg.de/2876415/tom-main-gate-into-mitochondria?c=2011019
Reposted by Victor Dubach
Proud to share our first lab pre-print: “SND3 is the membrane insertase within a fungal multipass translocon” where @tzujingyang.bsky.social solved the structure of a ribosome-associated SND3-translocon complex involved in ER membrane protein insertion ➡️ doi.org/10.1101/2025...
July 12, 2025 at 12:49 AM
Proud to share our first lab pre-print: “SND3 is the membrane insertase within a fungal multipass translocon” where @tzujingyang.bsky.social solved the structure of a ribosome-associated SND3-translocon complex involved in ER membrane protein insertion ➡️ doi.org/10.1101/2025...
Reposted by Victor Dubach
SND3 is the membrane insertase within a fungal multipass translocon https://www.biorxiv.org/content/10.1101/2025.07.08.663624v1
July 11, 2025 at 1:48 PM
SND3 is the membrane insertase within a fungal multipass translocon https://www.biorxiv.org/content/10.1101/2025.07.08.663624v1
Reposted by Victor Dubach
🎉We’re celebrating the #SCALE-it-Best-PhD-Awards-2025, honoring exceptional researchers! 🎓 This year, three remarkable dissertations were recognized, selected from a highly competitive and multidisciplinary pool of candidates. 🧵
June 5, 2025 at 9:41 AM
🎉We’re celebrating the #SCALE-it-Best-PhD-Awards-2025, honoring exceptional researchers! 🎓 This year, three remarkable dissertations were recognized, selected from a highly competitive and multidisciplinary pool of candidates. 🧵
Reposted by Victor Dubach
Looking for a tool to measure membrane thicknesses in tomograms (#TeamTomo)? Or curious about thickness differences within and across organelles? Check out my fellow @becklab.bsky.social PhD student @deglushk.bsky.social's excellent preprint:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
April 12, 2025 at 7:29 PM
Looking for a tool to measure membrane thicknesses in tomograms (#TeamTomo)? Or curious about thickness differences within and across organelles? Check out my fellow @becklab.bsky.social PhD student @deglushk.bsky.social's excellent preprint:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Victor Dubach
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
April 11, 2025 at 9:04 AM
New preprint on 3D heterochromatin architecture in human cells! Great collab with @sergiocruzleon.bsky.social & @johannesbetz.bsky.social from @hummerlab.bsky.social, @marinalusic.bsky.social & the Turoňová lab. Many thanks to my supervisor @becklab.bsky.social. bioRxiv: tinyurl.com/3a74uanv 🧵👇
Reposted by Victor Dubach
Get yourself a supervisor with whom you can laugh!
…So this happened two days ago… Incredibly grateful for all the fun and support over the years with @bjmurphylab.bsky.social and all the great people at @mpibp.bsky.social 🎓
…So this happened two days ago… Incredibly grateful for all the fun and support over the years with @bjmurphylab.bsky.social and all the great people at @mpibp.bsky.social 🎓
March 28, 2025 at 11:03 AM
Get yourself a supervisor with whom you can laugh!
…So this happened two days ago… Incredibly grateful for all the fun and support over the years with @bjmurphylab.bsky.social and all the great people at @mpibp.bsky.social 🎓
…So this happened two days ago… Incredibly grateful for all the fun and support over the years with @bjmurphylab.bsky.social and all the great people at @mpibp.bsky.social 🎓
Reposted by Victor Dubach
Happy International Women and Girls in STEM Day! Every mentor and act makes a difference - when we support a girl's curiosity or champion a female colleague, we inspire the next generation and one another. Let’s make STEM a place where all women & girls can thrive 🔬👩🏼🔬#WomenInSTEM
February 11, 2025 at 2:47 PM
Happy International Women and Girls in STEM Day! Every mentor and act makes a difference - when we support a girl's curiosity or champion a female colleague, we inspire the next generation and one another. Let’s make STEM a place where all women & girls can thrive 🔬👩🏼🔬#WomenInSTEM
Reposted by Victor Dubach
In case you wondered what it looks like "in real life" when the FluScreen of a Krios cryoEM is retracted/inserted: here you go. ❄️🔬
February 4, 2025 at 2:42 PM
In case you wondered what it looks like "in real life" when the FluScreen of a Krios cryoEM is retracted/inserted: here you go. ❄️🔬
Reposted by Victor Dubach
Exciting green news! 🦠 Do you know how certain microorganisms make a living by transforming CO2 into useful molecules? Check out our new work on the molecular choreography behind acetyl-CoA synthesis in the CODH/ACS protein complex. 👩🔬 🔗 www.biophys.mpg.de/2844976/micr...
January 31, 2025 at 1:14 PM
Exciting green news! 🦠 Do you know how certain microorganisms make a living by transforming CO2 into useful molecules? Check out our new work on the molecular choreography behind acetyl-CoA synthesis in the CODH/ACS protein complex. 👩🔬 🔗 www.biophys.mpg.de/2844976/micr...
Reposted by Victor Dubach
Congrats, Max! And big thanks and congratulations to our coauthors at MPI for Marine Microbiology, Bremen, MPI-CBG in Dresden, and in-house at the MPI of Biophysics! It's been great working with you all! @mpimarinemicrobio.bsky.social, @mpicbg.bsky.social sky.social, @hummerlab.bsky.social
Exciting green news! 🦠 Do you know how certain microorganisms make a living by transforming CO2 into useful molecules? Check out our new work on the molecular choreography behind acetyl-CoA synthesis in the CODH/ACS protein complex. 👩🔬 🔗 www.biophys.mpg.de/2844976/micr...
January 31, 2025 at 4:18 PM
Congrats, Max! And big thanks and congratulations to our coauthors at MPI for Marine Microbiology, Bremen, MPI-CBG in Dresden, and in-house at the MPI of Biophysics! It's been great working with you all! @mpimarinemicrobio.bsky.social, @mpicbg.bsky.social sky.social, @hummerlab.bsky.social
Reposted by Victor Dubach
I am very happy to share our latest work on the detailed cryo-EM structure of the NDH-PSI supercomplex of spinach. Thanks to Werner Kühlbrandt, Alex Hahn and @mpibp.bsky.social ! 🍃❄️🔬
You can find the paper in open access in Nature Structural and Molecular Biology:
www.nature.com/articles/s41...
You can find the paper in open access in Nature Structural and Molecular Biology:
www.nature.com/articles/s41...
Cryo-EM structure of the NDH–PSI–LHCI supercomplex from Spinacia oleracea - Nature Structural & Molecular Biology
Here, the authors report the structure of the nicotinamide adenine dinucleotide phosphate dehydrogenase–photosystem I–light-harvesting complex I supercomplex, providing insights into subunit interacti...
www.nature.com
January 27, 2025 at 12:18 PM
I am very happy to share our latest work on the detailed cryo-EM structure of the NDH-PSI supercomplex of spinach. Thanks to Werner Kühlbrandt, Alex Hahn and @mpibp.bsky.social ! 🍃❄️🔬
You can find the paper in open access in Nature Structural and Molecular Biology:
www.nature.com/articles/s41...
You can find the paper in open access in Nature Structural and Molecular Biology:
www.nature.com/articles/s41...
Reposted by Victor Dubach
Check out our latest publication in @naturecellbiology.bsky.social on the role of phase separation in selective autophagy initiation! This was done in a fantastic collaboration with
@kraftlabfr.bsky.social
www.nature.com/articles/s41...
Short teaser below 👇👇👇
@kraftlabfr.bsky.social
www.nature.com/articles/s41...
Short teaser below 👇👇👇
Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy - Nature Cell Biology
Licheva, Pflaum, Babic, Mancilla et al. show that low-affinity cargo–receptor interactions promote autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub ...
www.nature.com
January 8, 2025 at 3:11 PM
Check out our latest publication in @naturecellbiology.bsky.social on the role of phase separation in selective autophagy initiation! This was done in a fantastic collaboration with
@kraftlabfr.bsky.social
www.nature.com/articles/s41...
Short teaser below 👇👇👇
@kraftlabfr.bsky.social
www.nature.com/articles/s41...
Short teaser below 👇👇👇
Reposted by Victor Dubach
Hello bluesky, we’re excited to be here! To start off, we want to share our latest work on the FDX2-bound core ISC complex, which is now published in Nature Comms.
Congrats to @ralfsteinhilper.bsky.social and everyone else involved! 🎉
www.nature.com/articles/s41...
Congrats to @ralfsteinhilper.bsky.social and everyone else involved! 🎉
www.nature.com/articles/s41...
Two-stage binding of mitochondrial ferredoxin-2 to the core iron-sulfur cluster assembly complex - Nature Communications
De novo [2Fe-2S] cluster synthesis by the mitochondrial ISC complex requires electrons from ferredoxin-2 (FDX2). The authors map FDX2 binding to the core ISC complex, showing that FDX2 can bind in two...
www.nature.com
December 5, 2024 at 11:19 AM
Hello bluesky, we’re excited to be here! To start off, we want to share our latest work on the FDX2-bound core ISC complex, which is now published in Nature Comms.
Congrats to @ralfsteinhilper.bsky.social and everyone else involved! 🎉
www.nature.com/articles/s41...
Congrats to @ralfsteinhilper.bsky.social and everyone else involved! 🎉
www.nature.com/articles/s41...
Reposted by Victor Dubach
It's awesome that most of the coauthors are on Bluesky! 🤩
I had so much fun learning, collaborating with @amardeeep.bsky.social from @kevincorbett.bsky.social lab.
Thanks to @jessicakoenig.bsky.social and Martin Baaske from @eugenekimlab.bsky.social
I had so much fun learning, collaborating with @amardeeep.bsky.social from @kevincorbett.bsky.social lab.
Thanks to @jessicakoenig.bsky.social and Martin Baaske from @eugenekimlab.bsky.social
Happy to see our research on SMC Wadjet published in Molecular Cell. We showed DNA loop extrusion (LE) by a bacterial SMC, confirming LE is conserved across all life forms. Wadjet's LE activity is crucial for recognizing and restricting foreign plasmids, serving as a defense mechanism. 🧬🔬🧪
December 3, 2024 at 8:52 AM
It's awesome that most of the coauthors are on Bluesky! 🤩
I had so much fun learning, collaborating with @amardeeep.bsky.social from @kevincorbett.bsky.social lab.
Thanks to @jessicakoenig.bsky.social and Martin Baaske from @eugenekimlab.bsky.social
I had so much fun learning, collaborating with @amardeeep.bsky.social from @kevincorbett.bsky.social lab.
Thanks to @jessicakoenig.bsky.social and Martin Baaske from @eugenekimlab.bsky.social