Luka Velasevic
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velasevic.bsky.social
Luka Velasevic
@velasevic.bsky.social
PhD @EMBL Heidelberg working on functional metagenomics and molecular systems biology in the Zimmermann lab.
Previously MSc @LMU Munich specialized in ancient DNA research.
Reposted by Luka Velasevic
Richard so deserves this - a legend in bioinformatics and computational biology - work genome, human genome, Pfam, 1,000 genomes, Sam/bam format, bwa, vcf, psmc… and so many more
Congratulations to Richard Durbin on being awarded our Genetics Society Medal!
November 14, 2025 at 1:37 PM
My MSc lab slaying it again
As human groups migrated and settled across Holocene Eurasia, dogs often traveled with them and were sometimes traded among populations, researchers report in Science. The results reveal the integral role these animals played in culture and exchange. https://scim.ag/4peI4kl
Genomic evidence for the Holocene codispersal of dogs and humans across Eastern Eurasia
As the first domestic species, dogs likely dispersed with different cultural groups during the Late Pleistocene and Holocene. To test this hypothesis, we analyzed 73 ancient dog genomes, including 17 ...
scim.ag
November 14, 2025 at 10:55 AM
Reposted by Luka Velasevic
Happy to see our HT-PELSA paper now published in @natsmb.nature.com 🎊 Big thanks for the constructive review process! 📖Read the manuscript here (www.nature.com/articles/s41...) & check the thread for additional information ⬇️
November 5, 2025 at 10:15 AM
Apparently chimps are better at Bayesian stats than me
October 31, 2025 at 1:07 AM
Reposted by Luka Velasevic
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Reposted by Luka Velasevic
Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social
August 31, 2025 at 6:44 PM
Reposted by Luka Velasevic
Excited to share our preprint led by Carlos Voogdt et al

We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera.
www.biorxiv.org/content/10.1...
October 13, 2025 at 7:48 AM
Excited to join forces with you!
This semester, we also welcomed Luka, the newest PhD candidate of the Zimmermann group!

Luka is coming from Montenegro and will work on high-throughput exploration of the metagenomic sequence space.

Welcome🎉🎊
October 22, 2025 at 9:30 PM
Reposted by Luka Velasevic
The PopGen Vienna Seminar series schedule is ready for the next term (Sep-Jan). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website popgen-vienna.at/news/seminars/
September 2, 2025 at 8:59 AM
Reposted by Luka Velasevic
I regularly get derailed when someone tries to benchmark clustering methods, trying the find the "best" one or the one that agrees with "ground truth".

Which clustering of the below animals is the best or the true one? By row, or by column?
October 16, 2025 at 9:44 AM
Reposted by Luka Velasevic
From magnetic tapes to exabytes of data, Rolf Apweiler has seen it all!

As Rolf retires after more than four decades at EMBL, he shares his insights and favourite stories, including how all of EMBL-EBI’s data used to fit in the back of a car.

www.ebi.ac.uk/about/news/p...
October 16, 2025 at 11:19 AM
Reposted by Luka Velasevic
Acetaminophen is antifa
September 24, 2025 at 5:13 AM
Reposted by Luka Velasevic
📍Paper alert 📍

Our new preprint is available on: chemrxiv.org/engage/chemr...

Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including SCFA, indols, organic acids, and amino acid derivatives.
Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites
The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer....
chemrxiv.org
September 24, 2025 at 12:21 PM
Reposted by Luka Velasevic
Office (4/5): Welcome to the PIs offices

We are handling dogs, budgets, people, projects and databases.

Ines with Elly is running the dry lab
Wolfgang with Mo is running the wet lab

It’s such a privilege to work with all these wonderful people ❤️ and we have the best jobs we can imagine.
August 4, 2025 at 10:59 AM
Reposted by Luka Velasevic
🎉ONLINE @natgenet.nature.com

📰Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes.

By @julianeg.bsky.social, Giulia Cova, Stefan Mundlos and colleagues.

⬇️

www.nature.com/articles/s41...
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 10, 2025 at 12:05 PM