Tencho Tenev
@ttenev.bsky.social
Biologist, Senior Staff Scientist at @icrlondon.bsky.social
#TNFR and #TLR signaling; #immunogenic cell death; #necroptosis; #innate immunity; #immunotherapy; #cancer
#TNFR and #TLR signaling; #immunogenic cell death; #necroptosis; #innate immunity; #immunotherapy; #cancer
Great two day meeting organised by @icr.ac.uk . Lots of amazing talks and posters that culminated with keynote talk by Erik Sahai @eriksahailab.bsky.social . Well done to organisers.
June 24, 2025 at 3:55 PM
Great two day meeting organised by @icr.ac.uk . Lots of amazing talks and posters that culminated with keynote talk by Erik Sahai @eriksahailab.bsky.social . Well done to organisers.
Reposted by Tencho Tenev
Tumor cells hijack the mRNA export pathway to obstruct nuclear export of retroelement transcripts for viral mimicry inhibition and immune evasion
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
April 9, 2025 at 7:31 PM
Tumor cells hijack the mRNA export pathway to obstruct nuclear export of retroelement transcripts for viral mimicry inhibition and immune evasion
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Tencho Tenev
Effective recognition of double-stranded RNA in human cells does not require activation of the antiviral interferon pathway www.science.org/doi/10.1126/...
April 9, 2025 at 7:28 PM
Effective recognition of double-stranded RNA in human cells does not require activation of the antiviral interferon pathway www.science.org/doi/10.1126/...
Reposted by Tencho Tenev
We made it to 100! 📢💯 The #ubiquitin and #ubl Starter Pack now includes 100 profiles to follow if you’re interested in any aspect of the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.
January 21, 2025 at 11:10 AM
We made it to 100! 📢💯 The #ubiquitin and #ubl Starter Pack now includes 100 profiles to follow if you’re interested in any aspect of the field: signalling, structure and biochemistry, biology, mechanisms, proteostasis, TPD, chemical biology… Check out the list and let me know if you are missing.
Reposted by Tencho Tenev
Amazing role of non-pathogenic viruses in providing a benefit to host through suppression of cancer development www.cell.com/cancer-cell/...
Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
Sun-damaged normal skin contains many clonal mutations. Son et al. show that commensal
papillomaviruses residing in keratinocytes help virus-specific CD8+ T cells detect
and suppress the mutant clones...
www.cell.com
January 17, 2025 at 9:15 AM
Amazing role of non-pathogenic viruses in providing a benefit to host through suppression of cancer development www.cell.com/cancer-cell/...
Reposted by Tencho Tenev
Working with a great team to organize
@keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26
@patientled.bsky.social @daltmann.bsky.social
August 10-13, 2025 | Santa Fe
Hope to see you there!
keysym.us/KSLongCOVID26
@keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26
@patientled.bsky.social @daltmann.bsky.social
August 10-13, 2025 | Santa Fe
Hope to see you there!
keysym.us/KSLongCOVID26
January 12, 2025 at 3:05 PM
Working with a great team to organize
@keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26
@patientled.bsky.social @daltmann.bsky.social
August 10-13, 2025 | Santa Fe
Hope to see you there!
keysym.us/KSLongCOVID26
@keystonesymposia.bsky.social on "#LongCOVID and Other Post-Acute Infection Syndromes #PAIS" #KSLongCOVID26
@patientled.bsky.social @daltmann.bsky.social
August 10-13, 2025 | Santa Fe
Hope to see you there!
keysym.us/KSLongCOVID26
Weekend paper to read:
doi.org/10.1186/s130...
doi.org/10.1186/s130...
Divergent paths of mammary gland involution: unveiling the cellular dynamics in abruptly and gradually involuted mouse models - Breast Cancer Research
Background Epidemiological studies associate an increase in breast cancer risk, particularly triple-negative breast cancer (TNBC), with lack of breastfeeding. This is more prevalent in African America...
doi.org
January 10, 2025 at 9:09 AM
Weekend paper to read:
doi.org/10.1186/s130...
doi.org/10.1186/s130...
What we eat? Royal Institution Christmas Lectures in three episodes starting soon.
www.bbc.co.uk/programmes/m...
www.bbc.co.uk/programmes/m...
BBC Four - Royal Institution Christmas Lectures, 2024: Chris van Tulleken - The Truth About Food, From Taste Buds to Toilet
Dr Chris van Tulleken explores the incredible journey food takes through our bodies.
www.bbc.co.uk
December 29, 2024 at 8:12 PM
What we eat? Royal Institution Christmas Lectures in three episodes starting soon.
www.bbc.co.uk/programmes/m...
www.bbc.co.uk/programmes/m...
Reposted by Tencho Tenev
After 11months on this platform, so happy to see the momentum finally happening!
Let’s repeat a proper introduction:
My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology
Let’s repeat a proper introduction:
My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology
November 23, 2024 at 6:52 AM
After 11months on this platform, so happy to see the momentum finally happening!
Let’s repeat a proper introduction:
My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology
Let’s repeat a proper introduction:
My lab studies how the #Microbiome together with #Nutrition influence #Development and Juvenile #Physiology using #Mice and #Drosophila as models… we also do lot’s of #Microbiology
Reposted by Tencho Tenev
Are you ready for this? We are on Bluesky too!!! Follow the account of NATURE CELL BIOLOGY below!
bsky.app/profile/natu...
bsky.app/profile/natu...
November 20, 2024 at 5:46 PM
Are you ready for this? We are on Bluesky too!!! Follow the account of NATURE CELL BIOLOGY below!
bsky.app/profile/natu...
bsky.app/profile/natu...
Reposted by Tencho Tenev
👋 fellow immunologists, it’s a pleasure to be with you all on bsky! I work on type I #interferons, I figured it would be neat to have a starter pack for those of us working on all things IFN! I’ll keep adding to it, let me know if you want to be included! #immunology #immunosky go.bsky.app/71vKZJA
November 20, 2024 at 7:36 AM
👋 fellow immunologists, it’s a pleasure to be with you all on bsky! I work on type I #interferons, I figured it would be neat to have a starter pack for those of us working on all things IFN! I’ll keep adding to it, let me know if you want to be included! #immunology #immunosky go.bsky.app/71vKZJA
Reposted by Tencho Tenev
We’ve jumped on board fully here on 🦋
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
November 19, 2024 at 10:11 PM
We’ve jumped on board fully here on 🦋
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
A starter pack of those working on our favourite cell … the T cell 🥰🙈🥰
If you want an add let us know
go.bsky.app/8B5P25c
Reposted by Tencho Tenev
Let's bring the #CellDeath community together here on 🦋
Just get in touch to join this Starter Pack
go.bsky.app/R6mGrKU
Just get in touch to join this Starter Pack
go.bsky.app/R6mGrKU
November 16, 2024 at 9:41 AM
Let's bring the #CellDeath community together here on 🦋
Just get in touch to join this Starter Pack
go.bsky.app/R6mGrKU
Just get in touch to join this Starter Pack
go.bsky.app/R6mGrKU
Good news for #Protacs www.nature.com/articles/d41...
PROTAC protein degraders to drug the undruggable enter phase 3 trials
Pharmaceutical companies are investing in therapies that target proteins for degradation, with trials ongoing for cancer, autoimmune diseases and neurological disorders.
www.nature.com
November 15, 2024 at 8:32 AM
Good news for #Protacs www.nature.com/articles/d41...