Tony McChrystal
@tonymac5.bsky.social
Freshly parachuted in from the cesspit formerly known as Twitter. Still hoping Everton become less poo, loving science and all things biology.
Be kind or I'll batter yous all.
Be kind or I'll batter yous all.
medicalxpress.com/news/2025-02...
Some of the advances in autoimmune conditions such as this may bring real benefits soon, hopefully. There's also the continuing work on 'inverse vaccines' against autoimmune diseases.
www.cas.org/resources/ca...
Some of the advances in autoimmune conditions such as this may bring real benefits soon, hopefully. There's also the continuing work on 'inverse vaccines' against autoimmune diseases.
www.cas.org/resources/ca...
Researchers discover a major driver of inflammatory pathology in autoimmune and chronic inflammatory diseases
Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that pat...
medicalxpress.com
February 10, 2025 at 4:56 PM
medicalxpress.com/news/2025-02...
Some of the advances in autoimmune conditions such as this may bring real benefits soon, hopefully. There's also the continuing work on 'inverse vaccines' against autoimmune diseases.
www.cas.org/resources/ca...
Some of the advances in autoimmune conditions such as this may bring real benefits soon, hopefully. There's also the continuing work on 'inverse vaccines' against autoimmune diseases.
www.cas.org/resources/ca...
Reposted by Tony McChrystal
My latest cartoon for @newscientist.com
February 10, 2025 at 12:27 PM
My latest cartoon for @newscientist.com
Reposted by Tony McChrystal
This could help a lot of people if it works out
medicalxpress.com/news/2025-02...
medicalxpress.com/news/2025-02...
Researchers discover a major driver of inflammatory pathology in autoimmune and chronic inflammatory diseases
Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that pat...
medicalxpress.com
February 10, 2025 at 11:25 AM
This could help a lot of people if it works out
medicalxpress.com/news/2025-02...
medicalxpress.com/news/2025-02...
Reposted by Tony McChrystal
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
February 10, 2025 at 8:21 AM
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
www.biorxiv.org/content/10.1...
Reposted by Tony McChrystal
Editing scientific content for political purity is turning MMWR into a compromised propaganda organ.
And why are the propaganda squads at CDC replacing specifically H5N1 bird flu studies?
I’ve got some pretty serious fascism- and flu-related concerns about this.
And why are the propaganda squads at CDC replacing specifically H5N1 bird flu studies?
I’ve got some pretty serious fascism- and flu-related concerns about this.
What happened to CDC's bird flu studies and why did they publish about wildfires instead?
Sources tell us Trump officials are now wielding unprecedented control over agency's flagship scientific journal
"The MMWR has lost its autonomy"
www.cbsnews.com/news/trump-o...
Sources tell us Trump officials are now wielding unprecedented control over agency's flagship scientific journal
"The MMWR has lost its autonomy"
www.cbsnews.com/news/trump-o...
Trump officials exerting unprecedented control over CDC scientific journal
"The MMWR has lost its autonomy," one health official told CBS News.
www.cbsnews.com
February 9, 2025 at 3:37 PM
Editing scientific content for political purity is turning MMWR into a compromised propaganda organ.
And why are the propaganda squads at CDC replacing specifically H5N1 bird flu studies?
I’ve got some pretty serious fascism- and flu-related concerns about this.
And why are the propaganda squads at CDC replacing specifically H5N1 bird flu studies?
I’ve got some pretty serious fascism- and flu-related concerns about this.
Reposted by Tony McChrystal
Cool image of clouds over the Northern Hemisphere of Mars taken by CNSA's Tianwen 1
Full size & more info: flic.kr/p/2qKEu4g
Image Processing: Andrea Luck
Raw Image: CNSA/CLEP/PEC/MoRIC
2024-01-27 at 3230 km
From the left: Milankovic Crater, Alba Mons and Tempe Terra
North is up
Full size & more info: flic.kr/p/2qKEu4g
Image Processing: Andrea Luck
Raw Image: CNSA/CLEP/PEC/MoRIC
2024-01-27 at 3230 km
From the left: Milankovic Crater, Alba Mons and Tempe Terra
North is up
February 9, 2025 at 1:10 AM
Cool image of clouds over the Northern Hemisphere of Mars taken by CNSA's Tianwen 1
Full size & more info: flic.kr/p/2qKEu4g
Image Processing: Andrea Luck
Raw Image: CNSA/CLEP/PEC/MoRIC
2024-01-27 at 3230 km
From the left: Milankovic Crater, Alba Mons and Tempe Terra
North is up
Full size & more info: flic.kr/p/2qKEu4g
Image Processing: Andrea Luck
Raw Image: CNSA/CLEP/PEC/MoRIC
2024-01-27 at 3230 km
From the left: Milankovic Crater, Alba Mons and Tempe Terra
North is up
Reposted by Tony McChrystal
If you have encountered pediatric interdigitating dendritic cell sarcoma (IDCS), indeterminate dendritic cell histiocytosis or other (non-LCH) histiocytic sarcomas cases—please see short thread below & reach out to Sri Kosuri: #sarcoma #medsky #biosky
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:41 PM
Honestly, if this keeps going, it will be the single biggest, stupidest, most damaging self-inflicted wound any country has ever inflicted on itself.
www.houstonchronicle.com/politics/art...
30,000 tons of food from American Farmers rotting on the piers
30,000 tons of food from American Farmers rotting on the piers
30,000 tons of food stuck in Houston port after Trump halts foreign aid
The food was purchased through a USAID program to feed hungry people overseas is stuck at a warehouse in Houston's port.
www.houstonchronicle.com
February 8, 2025 at 9:45 PM
Honestly, if this keeps going, it will be the single biggest, stupidest, most damaging self-inflicted wound any country has ever inflicted on itself.
Reposted by Tony McChrystal
Homelessness.
160,000 children in temporary accommodation.
Lack of permanent home contributing factor in death of 74 (if not many more) kids since 2019.
39,000 families & pensioners placed out of borough.
All @privateeyenews.bsky.social figures.
The St Albans exhibition is a timely reminder...
160,000 children in temporary accommodation.
Lack of permanent home contributing factor in death of 74 (if not many more) kids since 2019.
39,000 families & pensioners placed out of borough.
All @privateeyenews.bsky.social figures.
The St Albans exhibition is a timely reminder...
Outsiders exposed: powerful photos reveal the ruthless reality of homelessness
A striking exhibition in St Albans reveals the harsh realities of homelessness through powerful black-and-white photography
eastangliabylines.co.uk
February 8, 2025 at 9:51 AM
Homelessness.
160,000 children in temporary accommodation.
Lack of permanent home contributing factor in death of 74 (if not many more) kids since 2019.
39,000 families & pensioners placed out of borough.
All @privateeyenews.bsky.social figures.
The St Albans exhibition is a timely reminder...
160,000 children in temporary accommodation.
Lack of permanent home contributing factor in death of 74 (if not many more) kids since 2019.
39,000 families & pensioners placed out of borough.
All @privateeyenews.bsky.social figures.
The St Albans exhibition is a timely reminder...
Reposted by Tony McChrystal
Loise from the Outsiders project. She spent fours years sleeping rough in London with her baby, afraid of trying to get support due to the hostile environment. They lived on scraps of discarded food from bins, or which had been dropped on the ground.
February 8, 2025 at 9:49 AM
Loise from the Outsiders project. She spent fours years sleeping rough in London with her baby, afraid of trying to get support due to the hostile environment. They lived on scraps of discarded food from bins, or which had been dropped on the ground.
Went to see Companion earlier this week. Good thriller, some heavy sci-fi themes handled adeptly, with black humour and excellent action. Sophie Thatcher was amazing.
February 8, 2025 at 9:59 AM
Went to see Companion earlier this week. Good thriller, some heavy sci-fi themes handled adeptly, with black humour and excellent action. Sophie Thatcher was amazing.
Reposted by Tony McChrystal
Well shit.
February 8, 2025 at 5:04 AM
Well shit.
Reposted by Tony McChrystal
A novel CAR T-cell therapy achieved an 82% response rate in lymphoma patients, demonstrating efficacy even at low doses.
by Park JH, Palomba ML (...) Sadelain M et 31 al. in J Clin Oncol #MedSky
📖 read the article: https://ascopubs.org/doi/10.1200/JCO-24-02424
by Park JH, Palomba ML (...) Sadelain M et 31 al. in J Clin Oncol #MedSky
📖 read the article: https://ascopubs.org/doi/10.1200/JCO-24-02424
February 8, 2025 at 6:33 AM
A novel CAR T-cell therapy achieved an 82% response rate in lymphoma patients, demonstrating efficacy even at low doses.
by Park JH, Palomba ML (...) Sadelain M et 31 al. in J Clin Oncol #MedSky
📖 read the article: https://ascopubs.org/doi/10.1200/JCO-24-02424
by Park JH, Palomba ML (...) Sadelain M et 31 al. in J Clin Oncol #MedSky
📖 read the article: https://ascopubs.org/doi/10.1200/JCO-24-02424
Reposted by Tony McChrystal
SCOOP: FBI director nominee Kash Patel disclosed he received up to $5M in shares of a mysterious entity in the Cayman Islands called Elite Depot. Elite Depot is a parent organization of fast-fashion giant Shein, according to corporate records I reviewed www.wired.com/story/kash-p...
Trump's FBI Pick Kash Patel Took Up to $5M in Stock from Chinese Ecommerce Giant Shein
Donald Trump’s pick for FBI director told senators he has no plans to divest his shares, which his financial disclosure form says were received in exchange for consulting services.
www.wired.com
February 7, 2025 at 9:23 PM
SCOOP: FBI director nominee Kash Patel disclosed he received up to $5M in shares of a mysterious entity in the Cayman Islands called Elite Depot. Elite Depot is a parent organization of fast-fashion giant Shein, according to corporate records I reviewed www.wired.com/story/kash-p...
Reposted by Tony McChrystal
The N.I.H. will cut about $4 Billion from federal research grants that support cancer, virus and heart disease research.
This is a direct attack on science, and America's leadership in medical innovation.
This is the kind of "winning" they want? Seriously?
This is a direct attack on science, and America's leadership in medical innovation.
This is the kind of "winning" they want? Seriously?
February 8, 2025 at 6:30 AM
The N.I.H. will cut about $4 Billion from federal research grants that support cancer, virus and heart disease research.
This is a direct attack on science, and America's leadership in medical innovation.
This is the kind of "winning" they want? Seriously?
This is a direct attack on science, and America's leadership in medical innovation.
This is the kind of "winning" they want? Seriously?
Reposted by Tony McChrystal
SCOOP: A US Treasury threat intelligence analysis has designated DOGE staff an ‘insider threat'. An internal email reviewed by WIRED calls DOGE staff's access to federal payments systems “the single biggest insider threat risk the Bureau of the Fiscal Service has ever faced.”
A US Treasury Threat Intelligence Analysis Designates DOGE Staff as ‘Insider Threat’
An internal email reviewed by WIRED calls DOGE staff's access to federal payments systems “the single biggest insider threat risk the Bureau of the Fiscal Service has ever faced.”
wrd.cm
February 7, 2025 at 7:47 PM
SCOOP: A US Treasury threat intelligence analysis has designated DOGE staff an ‘insider threat'. An internal email reviewed by WIRED calls DOGE staff's access to federal payments systems “the single biggest insider threat risk the Bureau of the Fiscal Service has ever faced.”
Reposted by Tony McChrystal
BREAKING: A federal judge has blocked Elon Musk’s DOGE from accessing sensitive US Treasury Department material. He set a hearing for February 14th.
Federal judge blocks Elon Musk's DOGE from accessing sensitive US Treasury Department material
Those records contain personal data such as Social Security and bank account numbers for millions of Americans.
apnews.com
February 8, 2025 at 6:47 AM
BREAKING: A federal judge has blocked Elon Musk’s DOGE from accessing sensitive US Treasury Department material. He set a hearing for February 14th.
advanced.onlinelibrary.wiley.com/doi/10.1002/...
This is fascinating research. Probably a long time till any treatment is possible, but reverting cancerous cells to healthy cells would be amazing.
This is fascinating research. Probably a long time till any treatment is possible, but reverting cancerous cells to healthy cells would be amazing.
Attractor Landscape Analysis Reveals a Reversion Switch in the Transition of Colorectal Tumorigenesis
REVERT (REVERse Transition) is presented, a systems framework developed to identify a reversion switch in the transition process of tumorigenesis through comprehensive attractor landscape analysis of...
advanced.onlinelibrary.wiley.com
February 8, 2025 at 6:48 AM
advanced.onlinelibrary.wiley.com/doi/10.1002/...
This is fascinating research. Probably a long time till any treatment is possible, but reverting cancerous cells to healthy cells would be amazing.
This is fascinating research. Probably a long time till any treatment is possible, but reverting cancerous cells to healthy cells would be amazing.
Reposted by Tony McChrystal
You've probably heard that "we are stardust," but this graphic breaks it down and tells you what kind of stars your dust came from--and which elements didn't come from stars at all. 🧪
svs.gsfc.nasa.gov/13873/
svs.gsfc.nasa.gov/13873/
January 28, 2025 at 7:10 PM
You've probably heard that "we are stardust," but this graphic breaks it down and tells you what kind of stars your dust came from--and which elements didn't come from stars at all. 🧪
svs.gsfc.nasa.gov/13873/
svs.gsfc.nasa.gov/13873/
Reposted by Tony McChrystal
New: We spoke to government IT employees/contractors about DOGE. Their warnings were dire. The people who maintain the systems that keep the country working are terrified. "This is the largest data breach and the largest IT security breach in our country’s history—at least that’s publicly known."
The Government’s Computing Experts Say They Are Terrified
Four IT professionals lay out just how destructive Elon Musk’s incursion into the U.S. government could be.
www.theatlantic.com
February 7, 2025 at 2:14 PM
New: We spoke to government IT employees/contractors about DOGE. Their warnings were dire. The people who maintain the systems that keep the country working are terrified. "This is the largest data breach and the largest IT security breach in our country’s history—at least that’s publicly known."
Actions are going to meet consequences. Unfortunately, with infectious diseases and anti-vaxxers, it's usually the most vulnerable who face those consequences.
🚨Measles mounts in an undervaccinated Texas county. Hospitalizations & 9 cases. Many more expected.
This may be the first big outbreak of 2025 but probably not the last, with vaccine misinformation espoused at the highest levels of government.
My latest:
kffhealthnews.org/news/article...
This may be the first big outbreak of 2025 but probably not the last, with vaccine misinformation espoused at the highest levels of government.
My latest:
kffhealthnews.org/news/article...
Measles Outbreak Mounts Among Children in One of Texas’ Least Vaccinated Counties - KFF Health News
With hospitalizations and at least a dozen cases, health officials race to contain a growing outbreak in a community with low vaccination.
kffhealthnews.org
February 7, 2025 at 5:39 PM
Actions are going to meet consequences. Unfortunately, with infectious diseases and anti-vaxxers, it's usually the most vulnerable who face those consequences.