TJ Browne
@tjbrowne.bsky.social
Postdoc in the spinal cord connections lab (Graham Lab) at Uni Newcastle Upon-thePacific (Aus) studying circuits of the Dorsal horn with a focus on projection neurons. Patching, imaging, love of fluorescent eye candy.
Dad to 2 ratbags and husband to 1.
Dad to 2 ratbags and husband to 1.
This is seriously cool
✨ Announcing a new glutamate indicator - iGluSnFR4! ✨
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.
More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...
🧠📈
March 26, 2025 at 6:22 AM
This is seriously cool
Reposted by TJ Browne
New preprint from the Todd / Bell labs now on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1...
Expression of Tacr1 and Gpr83 by spinal projection neurons
Anterolateral system (ALS) projection neurons underlie perception of pain, itch and skin temperature. These cells are heterogeneous, and there have therefore been many attempts to define functional po...
www.biorxiv.org
March 20, 2025 at 1:28 PM
New preprint from the Todd / Bell labs now on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1...
Tour de force of central processing hubs from the gut. Awesome
Splanchnic and pelvic spinal afferent pathways relay sensory information from the mouse colorectum into distinct brainstem circuits. https://www.biorxiv.org/content/10.1101/2025.02.24.639793v1
February 26, 2025 at 8:57 AM
Tour de force of central processing hubs from the gut. Awesome
Fantastic opportunity
Anyone interested in a PhD in pain research, we have a fully-funded position available in the Weir lab.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow on FindAPhD.com
PhD Project - Human sensory neuron and macrophage co-culture; developing a model to test agents capable of disrupting painful neuroimmune signalling at University of Glasgow, listed on FindAPhD.com
www.findaphd.com
January 19, 2025 at 11:05 PM
Fantastic opportunity
What a year for the spinal cord connections lab!
Awesome news in the rundown of 2024.
Now for 2025!
Awesome news in the rundown of 2024.
Now for 2025!
FUNDING SUCCESS! Congratulations to Program Chair Professor Brett Graham on his National Health and Medical Research Council (NHMRC) Ideas Grant.
@hmriaustralia.bsky.social
@hmriaustralia.bsky.social
January 9, 2025 at 2:17 AM
What a year for the spinal cord connections lab!
Awesome news in the rundown of 2024.
Now for 2025!
Awesome news in the rundown of 2024.
Now for 2025!
Reposted by TJ Browne
Interested in potential sex differences in gene expression in adult mouse spinal cord neurons? Excitatory versus inhibitory dorsal horn neurons? Check out this online tool and technical report that enables you to dig deeper. 👇😊
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
An Open‐Source Tool for Investigation of Differential RNA Expression Between Spinal Cord Cells of Male and Female Mice
Chronic pain is a highly debilitating condition that differs by type, prevalence, and severity between men and women. To uncover the molecular underpinnings of these differences, it is critical to an....
onlinelibrary.wiley.com
December 16, 2024 at 1:42 PM
Interested in potential sex differences in gene expression in adult mouse spinal cord neurons? Excitatory versus inhibitory dorsal horn neurons? Check out this online tool and technical report that enables you to dig deeper. 👇😊
onlinelibrary.wiley.com/doi/10.1002/...
onlinelibrary.wiley.com/doi/10.1002/...
Please?
Would you like to see @biorxivpreprint.bsky.social add a share to blue sky button?! I know I would! Share this post to let @richardsever.bsky.social @erictopol.bsky.social and others at bioarxiv know!
December 2, 2024 at 7:32 PM
Please?
I have stolen our research programs post from the other place. We were fortunate enough to receive funding from ARC. Bring on the experiments #neuroskyence #painresearch @spinalcordguy.bsky.social
November 29, 2024 at 10:27 PM
I have stolen our research programs post from the other place. We were fortunate enough to receive funding from ARC. Bring on the experiments #neuroskyence #painresearch @spinalcordguy.bsky.social
I forgot #fluorescencefriday patching away last night.
Spinal projection neurons in a sagittal section, amongst subP-IR terminals
Spinal projection neurons in a sagittal section, amongst subP-IR terminals
November 29, 2024 at 10:18 PM
I forgot #fluorescencefriday patching away last night.
Spinal projection neurons in a sagittal section, amongst subP-IR terminals
Spinal projection neurons in a sagittal section, amongst subP-IR terminals
Reposted by TJ Browne
Also contributing to #FluorescenceFriday
(also follow our lab account @erturklab.bsky.social for more stuff like this)
(also follow our lab account @erturklab.bsky.social for more stuff like this)
November 22, 2024 at 2:21 PM
Also contributing to #FluorescenceFriday
(also follow our lab account @erturklab.bsky.social for more stuff like this)
(also follow our lab account @erturklab.bsky.social for more stuff like this)
#FluorescenceFriday has been epic! Thanks for sharing!
I’ll put up a very boring characterisation of a transgenic line. Sagittal spinal section showing GC6 expression (green), inhibitory (blue/magenta)and excitatory neurons (red only)
I’ll put up a very boring characterisation of a transgenic line. Sagittal spinal section showing GC6 expression (green), inhibitory (blue/magenta)and excitatory neurons (red only)
November 22, 2024 at 1:13 PM
#FluorescenceFriday has been epic! Thanks for sharing!
I’ll put up a very boring characterisation of a transgenic line. Sagittal spinal section showing GC6 expression (green), inhibitory (blue/magenta)and excitatory neurons (red only)
I’ll put up a very boring characterisation of a transgenic line. Sagittal spinal section showing GC6 expression (green), inhibitory (blue/magenta)and excitatory neurons (red only)
Reposted by TJ Browne
Happy #FluorescenceFriday !
Let's celebrate with a colorful image of a developing ventral spinal cord of a 🐣 embryo.
#neuroscience #microscopy
Let's celebrate with a colorful image of a developing ventral spinal cord of a 🐣 embryo.
#neuroscience #microscopy
November 22, 2024 at 7:35 AM
Happy #FluorescenceFriday !
Let's celebrate with a colorful image of a developing ventral spinal cord of a 🐣 embryo.
#neuroscience #microscopy
Let's celebrate with a colorful image of a developing ventral spinal cord of a 🐣 embryo.
#neuroscience #microscopy
Lateral Lamina V Projection Neurons labelled with Brainbow. #ArtorScience #neuroskyence
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 19, 2024 at 11:11 AM
Lateral Lamina V Projection Neurons labelled with Brainbow. #ArtorScience #neuroskyence
www.nature.com/articles/s41...
www.nature.com/articles/s41...
First post to bsky eep.. Work from my PhD was (finally) accepted: www.nature.com/articles/s41.... The main findings: as spinal projection neurons axons ascend to the brain they are influencing spinal circuits, adding a layer of complexity to their role and function locally. More details below...
Lateral lamina V projection neuron axon collaterals connect sensory processing across the dorsal horn of the mouse spinal cord - Scientific Reports
Scientific Reports - Lateral lamina V projection neuron axon collaterals connect sensory processing across the dorsal horn of the mouse spinal cord
www.nature.com
November 19, 2024 at 11:04 AM
First post to bsky eep.. Work from my PhD was (finally) accepted: www.nature.com/articles/s41.... The main findings: as spinal projection neurons axons ascend to the brain they are influencing spinal circuits, adding a layer of complexity to their role and function locally. More details below...