Sara E. Jager
@thisissarajager.bsky.social
Pain scientist by day, comic-creator by night
Website: www.saraejager.com
Website: www.saraejager.com
Reposted by Sara E. Jager
Stuart Bevan and I are offering an exciting MRC DTP-funded PhD project exploring the mechanisms of pain in Long COVID.
Find out more about the project here:
🔗 tinyurl.com/3caseacv
Application deadline: 28th October
@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social
Find out more about the project here:
🔗 tinyurl.com/3caseacv
Application deadline: 28th October
@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social
October 6, 2025 at 9:09 AM
Stuart Bevan and I are offering an exciting MRC DTP-funded PhD project exploring the mechanisms of pain in Long COVID.
Find out more about the project here:
🔗 tinyurl.com/3caseacv
Application deadline: 28th October
@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social
Find out more about the project here:
🔗 tinyurl.com/3caseacv
Application deadline: 28th October
@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social
Reposted by Sara E. Jager
We present the first subset-specific proteomic signature of electrophysiologically-defined, pain-sensing neurons. One step closer to uniting function with molecules- one neuron at a time. Thanks to all who have contributed, especially @coscialab.bsky.social @garyrlewin.bsky.social #neuroscience
Ultrasensitive proteomics uncovers nociceptor diversity and novel pain targets https://www.biorxiv.org/content/10.1101/2025.09.20.677124v1
September 22, 2025 at 6:12 PM
We present the first subset-specific proteomic signature of electrophysiologically-defined, pain-sensing neurons. One step closer to uniting function with molecules- one neuron at a time. Thanks to all who have contributed, especially @coscialab.bsky.social @garyrlewin.bsky.social #neuroscience
On my way home after an excellent trip. First, I went to Poland to visit @mwklab.bsky.social and give a talk together with @gg9761.bsky.social and Jimena Perez-Sanchez. Next, we all went to Berlin 🚂 to participate in #NeuPSIG where I got to hang out with more of my favorite scientists! #PainResearch
September 7, 2025 at 2:03 PM
On my way home after an excellent trip. First, I went to Poland to visit @mwklab.bsky.social and give a talk together with @gg9761.bsky.social and Jimena Perez-Sanchez. Next, we all went to Berlin 🚂 to participate in #NeuPSIG where I got to hang out with more of my favorite scientists! #PainResearch
🎉Inauguration of my comic about the importance of taking action to mitigate climate change!🎉
When researching for this I was very inspired by @katharinehayhoe.com. So much that she is in the comic 😅
I am grateful for my supportive colleagues 🤗
#SciArt
When researching for this I was very inspired by @katharinehayhoe.com. So much that she is in the comic 😅
I am grateful for my supportive colleagues 🤗
#SciArt
July 10, 2025 at 3:23 PM
🎉Inauguration of my comic about the importance of taking action to mitigate climate change!🎉
When researching for this I was very inspired by @katharinehayhoe.com. So much that she is in the comic 😅
I am grateful for my supportive colleagues 🤗
#SciArt
When researching for this I was very inspired by @katharinehayhoe.com. So much that she is in the comic 😅
I am grateful for my supportive colleagues 🤗
#SciArt
#PainResearch
Great PostDoc opportunity from Mat 🥳
Great PostDoc opportunity from Mat 🥳
And check us out here: 🔗 bit.ly/CancerNeuroPORT
WE ARE RECRUITING A POSTDOC!
WE ARE RECRUITING A POSTDOC!
PORT
Polski Ośrodek Rozwoju Technologii
bit.ly
July 8, 2025 at 6:26 AM
#PainResearch
Great PostDoc opportunity from Mat 🥳
Great PostDoc opportunity from Mat 🥳
Reposted by Sara E. Jager
Are you interested in omics approaches to pain and projection neurons? Why not join us? We’ve got a post-doc position available. Happy to discuss further with anyone who is interested. www.jobs.gla.ac.uk/job/research...
#neuroskyence #neurosci #PainResearch
#neuroskyence #neurosci #PainResearch
Research Associate
RESEARCH ASSOCIATECOLLEGE OF MVLSSCHOOL OF PSYCHOLOGY & NEUROSCIENCE GRADE 7 We are looking for an enthusiastic Research Associate to employ RNA sequencing and spatial transcriptomics in combin...
www.jobs.gla.ac.uk
July 2, 2025 at 3:19 PM
Are you interested in omics approaches to pain and projection neurons? Why not join us? We’ve got a post-doc position available. Happy to discuss further with anyone who is interested. www.jobs.gla.ac.uk/job/research...
#neuroskyence #neurosci #PainResearch
#neuroskyence #neurosci #PainResearch
Really looking forward to reading this preprint. I had not heard of TurboID before and then there is all the fun data!
Happy preprint day! We have a new transgenic & some sensory neuron compartment proteomics to share #TeamMassSpec
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 22, 2025 at 5:44 AM
Really looking forward to reading this preprint. I had not heard of TurboID before and then there is all the fun data!
If you love satellite glial cells (SGCs) then you have got to read about Ole Ahlgreen's great work, part of which was done while he was a visiting PhD student in our lab: www.biorxiv.org/content/10.1...
Mapping satellite glial cell heterogeneity reveals distinct spatial organization and signifies functional diversity in the dorsal root ganglion
Satellite glial cells (SGCs) envelop the somata, axon hillock, and initial axon segment of sensory neurons in the dorsal root ganglia (DRG), playing a critical role in regulating the neuronal microenv...
www.biorxiv.org
May 27, 2025 at 6:20 AM
Reposted by Sara E. Jager
If you love satellite glial cells (SGCs) then you have got to read about Ole Ahlgreen's great work, part of which was done while he was a visiting PhD student in our lab: www.biorxiv.org/content/10.1...
Mapping satellite glial cell heterogeneity reveals distinct spatial organization and signifies functional diversity in the dorsal root ganglion
Satellite glial cells (SGCs) envelop the somata, axon hillock, and initial axon segment of sensory neurons in the dorsal root ganglia (DRG), playing a critical role in regulating the neuronal microenv...
www.biorxiv.org
May 22, 2025 at 11:12 PM
If you love satellite glial cells (SGCs) then you have got to read about Ole Ahlgreen's great work, part of which was done while he was a visiting PhD student in our lab: www.biorxiv.org/content/10.1...
This morning at 9AM we have our staff meeting. The announcement makes me think that maybe we do indeed have a problematic drinking culture 🫣😅
January 30, 2025 at 6:31 AM
This morning at 9AM we have our staff meeting. The announcement makes me think that maybe we do indeed have a problematic drinking culture 🫣😅
The pre-print game is strong these last weeks of the year! 🤩 #PainResearch 🧪
Preprint alert: Using human microneurography protocols in PatchSeq experiments on pig DRGs we identify the molecular identity of human dermal CMi-fibers (sleeping nociceptors). We provide an integrated pig-human-more transcriptomic atlas and identify OSMR and SST as marker, backed by human expts.
Molecular architecture of human dermal sleeping nociceptors https://www.biorxiv.org/content/10.1101/2024.12.20.629638v1
December 22, 2024 at 6:20 PM
The pre-print game is strong these last weeks of the year! 🤩 #PainResearch 🧪
Check out this pre-print to get the newest theory behind movement control 🧪
Loads of beautiful figures to admire and complicated math to challenge the mind of any biologist 😅
Loads of beautiful figures to admire and complicated math to challenge the mind of any biologist 😅
New version of our preprint available. The supplementary information is also available.
"Spatial and network principles behind neural generation of locomotion"
www.biorxiv.org/content/10.1...
"Spatial and network principles behind neural generation of locomotion"
www.biorxiv.org/content/10.1...
Spatial and network principles behind neural generation of locomotion
Generation of locomotion is a fundamental function of the spinal cord, yet the underlying principles remain unclear. In particular, the relationship between neuronal cell types, networks and functions...
www.biorxiv.org
December 21, 2024 at 10:21 AM
Check out this pre-print to get the newest theory behind movement control 🧪
Loads of beautiful figures to admire and complicated math to challenge the mind of any biologist 😅
Loads of beautiful figures to admire and complicated math to challenge the mind of any biologist 😅
I had a lot of fun hosting MicToMic (🔬to🎤) last Sunday! I interviewed 2 scientist-musicians about their research and they played some of their indie rock songs for us 🤩
We heard about phages, contractile injector systems and muscle research! 🧪
We heard about phages, contractile injector systems and muscle research! 🧪
December 18, 2024 at 10:20 AM
I had a lot of fun hosting MicToMic (🔬to🎤) last Sunday! I interviewed 2 scientist-musicians about their research and they played some of their indie rock songs for us 🤩
We heard about phages, contractile injector systems and muscle research! 🧪
We heard about phages, contractile injector systems and muscle research! 🧪
Gonna look at my results with new eyes after this preprint 🤩
I have some 3D imaged mouse leg after SNI that needs further analysis on the blood nerve barrier #PainResearch 🧪
I have some 3D imaged mouse leg after SNI that needs further analysis on the blood nerve barrier #PainResearch 🧪
Interested in #PainResearch and/or mural cells (#pericyte #BloodBrainBarrier)? This one may be for you! Our latest #neuroskyence research suggesting that cells at the blood nerve barrier may be particularly replete with pain-inducing substances 🧪 #painscience: www.biorxiv.org/content/10.1...
A role for fibroblast and mural cell subsets in models of neuropathic pain
Neuropathic pain is a particularly intractable type of chronic pain that can result from physical nerve damage due to surgery or entrapment. Here, we present data which suggest that a particular subcl...
www.biorxiv.org
December 17, 2024 at 7:29 AM
Gonna look at my results with new eyes after this preprint 🤩
I have some 3D imaged mouse leg after SNI that needs further analysis on the blood nerve barrier #PainResearch 🧪
I have some 3D imaged mouse leg after SNI that needs further analysis on the blood nerve barrier #PainResearch 🧪
Reposted by Sara E. Jager
Interested in #PainResearch and/or mural cells (#pericyte #BloodBrainBarrier)? This one may be for you! Our latest #neuroskyence research suggesting that cells at the blood nerve barrier may be particularly replete with pain-inducing substances 🧪 #painscience: www.biorxiv.org/content/10.1...
A role for fibroblast and mural cell subsets in models of neuropathic pain
Neuropathic pain is a particularly intractable type of chronic pain that can result from physical nerve damage due to surgery or entrapment. Here, we present data which suggest that a particular subcl...
www.biorxiv.org
December 16, 2024 at 4:55 PM
Interested in #PainResearch and/or mural cells (#pericyte #BloodBrainBarrier)? This one may be for you! Our latest #neuroskyence research suggesting that cells at the blood nerve barrier may be particularly replete with pain-inducing substances 🧪 #painscience: www.biorxiv.org/content/10.1...
Great thread! Looking forward to reading the pre-print 🤗
It's pre-printed! Thrilled to finally share some human DRG proteomics, integrated across omics datasets to explore sexual dimorphism in the periphery 🧪🧬🖥️ #PainResearch #NeuroSkyence
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Multi-omic integration with human DRG proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway
The peripheral nervous system has been widely implicated in pathological conditions that exhibit distinct clinical presentations in men and women, most notably in chronic pain disorders. Here, we expl...
www.biorxiv.org
December 11, 2024 at 7:07 AM
Great thread! Looking forward to reading the pre-print 🤗
Me and two of my favorite colleagues are bringing a bit of UK Christmas spirit to Denmark!
🎄🎁🎅🏻🕯️💕
🎄🎁🎅🏻🕯️💕
December 7, 2024 at 9:56 AM
Me and two of my favorite colleagues are bringing a bit of UK Christmas spirit to Denmark!
🎄🎁🎅🏻🕯️💕
🎄🎁🎅🏻🕯️💕
Very excited to dive into this paper! 🤩 Such beautiful videos and data 🧪
Imagine seeing a disease's impact on every cell in the body. Now, you can! We introduce MouseMapper, an AI tool to reveal system-wide disease perturbations. It reveals obesity-induced changes in facial nerves & body-wide inflammation 👉🧵https://biorxiv.org/content/10.1101/2024.08.18.608300v1.full.pdf
December 5, 2024 at 5:12 PM
Very excited to dive into this paper! 🤩 Such beautiful videos and data 🧪
Lab retreat with Madsen and Toft-Sørensen lab. Looking forward to spend the next few days with these great people!
#PainResearch 🧪
#PainResearch 🧪
November 28, 2024 at 5:06 PM
Lab retreat with Madsen and Toft-Sørensen lab. Looking forward to spend the next few days with these great people!
#PainResearch 🧪
#PainResearch 🧪
Home in rainy Denmark after a great time in London.
Thanks to George Goodwin and @denklab.bsky.social for inviting me back to give a seminar talk at King's on #PainResearch. I talked about 3D imaging of the brain, hind leg and spinal column.
It was amazing to see all of you 🤗 🧪
Thanks to George Goodwin and @denklab.bsky.social for inviting me back to give a seminar talk at King's on #PainResearch. I talked about 3D imaging of the brain, hind leg and spinal column.
It was amazing to see all of you 🤗 🧪
November 24, 2024 at 5:09 PM
Home in rainy Denmark after a great time in London.
Thanks to George Goodwin and @denklab.bsky.social for inviting me back to give a seminar talk at King's on #PainResearch. I talked about 3D imaging of the brain, hind leg and spinal column.
It was amazing to see all of you 🤗 🧪
Thanks to George Goodwin and @denklab.bsky.social for inviting me back to give a seminar talk at King's on #PainResearch. I talked about 3D imaging of the brain, hind leg and spinal column.
It was amazing to see all of you 🤗 🧪
Reposted by Sara E. Jager
I started (at @katesadlerphd.bsky.social's suggestion, thanks Kate for pushing me) a pain neuroscience and pain research starter pack. I am sure I have missed many people so if I missed you, I am sorry, but please just ask me to add you in the thread below and I will do that. go.bsky.app/KboKNhg
November 18, 2024 at 4:58 PM
I started (at @katesadlerphd.bsky.social's suggestion, thanks Kate for pushing me) a pain neuroscience and pain research starter pack. I am sure I have missed many people so if I missed you, I am sorry, but please just ask me to add you in the thread below and I will do that. go.bsky.app/KboKNhg
Reposted by Sara E. Jager
Hi BluSky Basic Science Researchers 🧪! Do you dislike statistics? This amazing resource really helped me and my team come to love it: lakens.github.io/statistical_... and here if you prefer video: www.coursera.org/learn/statis...
Improving your statistical inferences
Offered by Eindhoven University of Technology. This course aims to help you to draw better statistical inferences from empirical research. ... Enroll for free.
www.coursera.org
November 18, 2024 at 6:48 PM
Hi BluSky Basic Science Researchers 🧪! Do you dislike statistics? This amazing resource really helped me and my team come to love it: lakens.github.io/statistical_... and here if you prefer video: www.coursera.org/learn/statis...
Preparing for my talk at King's College London next week! 🧪 #PainResearch
The video shows a 3D imaged spinal column with spinal cord, DRGs and vertebrae bones.
Looking forward to catching up with @denklab.bsky.social and co.
The video shows a 3D imaged spinal column with spinal cord, DRGs and vertebrae bones.
Looking forward to catching up with @denklab.bsky.social and co.
November 15, 2024 at 12:35 PM
Preparing for my talk at King's College London next week! 🧪 #PainResearch
The video shows a 3D imaged spinal column with spinal cord, DRGs and vertebrae bones.
Looking forward to catching up with @denklab.bsky.social and co.
The video shows a 3D imaged spinal column with spinal cord, DRGs and vertebrae bones.
Looking forward to catching up with @denklab.bsky.social and co.
Reposted by Sara E. Jager
Our systematic review is now available in press at Pain - of interest to anyone studying spontaneous activity in neuropathic pain. The data are less clear-cut than we tend to assume...
journals.lww.com/pain/fulltex...
journals.lww.com/pain/fulltex...
November 22, 2023 at 6:39 PM
Our systematic review is now available in press at Pain - of interest to anyone studying spontaneous activity in neuropathic pain. The data are less clear-cut than we tend to assume...
journals.lww.com/pain/fulltex...
journals.lww.com/pain/fulltex...
Reposted by Sara E. Jager
Peripheral nerve injury results in a biased loss of sensory neuron sub-populations. #preprint
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Celebrating a paper submission week! Think we have a slightly better answer to this question now #NeuroSky
November 17, 2023 at 11:32 AM
Peripheral nerve injury results in a biased loss of sensory neuron sub-populations. #preprint
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...