TAGHIVscience
@taghivscience.bsky.social
Treatment Action Group's Basic Science, Vaccines & Cure Project, by Richard Jefferys. 🏳️⚧️
Primary Treatment Action Group account: https://bsky.app/profile/treatmentactiongroup.org
TAG website: https://www.treatmentactiongroup.org/
Primary Treatment Action Group account: https://bsky.app/profile/treatmentactiongroup.org
TAG website: https://www.treatmentactiongroup.org/
Glycan-reactive antibodies isolated from human #HIV vaccine trial participants show broad pathogen cross-reactivity journals.asm.org/doi/10.1128/... (open access)
Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity | Journal of Virology
Understanding how the human immune system recognizes and combats viruses is crucial
for developing better vaccines and treatments. Here, through characterization of the
B-cell receptor repertoires of ...
journals.asm.org
November 11, 2025 at 3:55 PM
Glycan-reactive antibodies isolated from human #HIV vaccine trial participants show broad pathogen cross-reactivity journals.asm.org/doi/10.1128/... (open access)
Parallel #HIV fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies elifesciences.org/articles/105... (open access) @elife.bsky.social
Parallel HIV-1 fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies
Fitness constraints on the HIV envelope protein are highly similar in humans and rhesus macaques, emphasizing the utility of macaque models of infection and antibody development.
elifesciences.org
November 11, 2025 at 3:49 PM
Parallel #HIV fitness landscapes shape viral dynamics in humans and macaques that develop broadly neutralizing antibodies elifesciences.org/articles/105... (open access) @elife.bsky.social
Reposted by TAGHIVscience
More of this. It’s time the world took a stand.
Exclusive: UK suspends some intelligence sharing with US over boat strike concerns in major break — CNN
The United Kingdom is no longer sharing intelligence with the US about suspected drug trafficking vessels in the Caribbean because it does not want to be complicit in US military strikes and believes ...
apple.news
November 11, 2025 at 3:16 PM
More of this. It’s time the world took a stand.
Reposted by TAGHIVscience
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
November 11, 2025 at 1:20 AM
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
Reposted by TAGHIVscience
Applications are open for the NIH-sponsored undergraduate Research Opportunities HIV RNA (ROHR) program for Summer 2026. Successful applicants will get to carry out a research project at a major university and attend a conference at the NIH. Please spread the word!
sites.google.com/a/umich.edu/...
sites.google.com/a/umich.edu/...
November 10, 2025 at 3:47 PM
Applications are open for the NIH-sponsored undergraduate Research Opportunities HIV RNA (ROHR) program for Summer 2026. Successful applicants will get to carry out a research project at a major university and attend a conference at the NIH. Please spread the word!
sites.google.com/a/umich.edu/...
sites.google.com/a/umich.edu/...
Reposted by TAGHIVscience
Most people never have a house fire. So why are we wasting money on a fire department?
Tell me you don’t understand risk pools without telling me you don’t understand risk pools
November 10, 2025 at 3:43 PM
Most people never have a house fire. So why are we wasting money on a fire department?
Reposted by TAGHIVscience
Today's timely post breaks down how the Trump administration secretly hijacked employees' email accounts to transmit partisan messages during the shutdown.
Unless you think the government will never shut down again...
with @lizdye.bsky.social
www.lawandchaospod.com/p/court-slap...
Unless you think the government will never shut down again...
with @lizdye.bsky.social
www.lawandchaospod.com/p/court-slap...
Court Slaps Sock Puppet Emails Out Of Trump's Bruised Hand
Civil servants have First Amendment rights.
www.lawandchaospod.com
November 10, 2025 at 3:10 PM
Today's timely post breaks down how the Trump administration secretly hijacked employees' email accounts to transmit partisan messages during the shutdown.
Unless you think the government will never shut down again...
with @lizdye.bsky.social
www.lawandchaospod.com/p/court-slap...
Unless you think the government will never shut down again...
with @lizdye.bsky.social
www.lawandchaospod.com/p/court-slap...
Reposted by TAGHIVscience
New Pipeline Report Alert - TAG just released the 2025 “Long-Acting Therapies Trials Tracker for Hepatitis C, Opioid Use and Overdose Prevention Therapy, and Malaria. Check it out here: www.treatmentactiongroup.org/resources/pi...
November 5, 2025 at 2:57 PM
New Pipeline Report Alert - TAG just released the 2025 “Long-Acting Therapies Trials Tracker for Hepatitis C, Opioid Use and Overdose Prevention Therapy, and Malaria. Check it out here: www.treatmentactiongroup.org/resources/pi...
Reposted by TAGHIVscience
We have updated our call script so you can let your Senators know how you feel about this (TERRIBLE) deal they just advanced...
👉🏽 5calls.org/issue/federa...
👉🏽 5calls.org/issue/federa...
UPDATE: Senate votes to advance a tentative deal to end the government shutdown, clearing a key hurdle.
Senators reach tentative deal to end the government shutdown
The deal, negotiated by a group of Democrats and GOP leaders, funds the government through Jan. 30. If it passes, it will still need to clear the House, which will likely take days.
nbcnews.to
November 10, 2025 at 4:23 AM
We have updated our call script so you can let your Senators know how you feel about this (TERRIBLE) deal they just advanced...
👉🏽 5calls.org/issue/federa...
👉🏽 5calls.org/issue/federa...
Reposted by TAGHIVscience
To be clear, this deal still needs to go through a debate and amendment process and more 60-vote thresholds to pass the Senate, and then it must pass the House. There's still room for constituent pressure.
November 10, 2025 at 4:39 AM
To be clear, this deal still needs to go through a debate and amendment process and more 60-vote thresholds to pass the Senate, and then it must pass the House. There's still room for constituent pressure.
Molecular basis for selection and inhibition of #HIV escape virus by T cells and KIR2DL2+NK cells www.nature.com/articles/s41... (open access) @natcomms.nature.com
Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2+NK cells - Nature Communications
HIV replication has been shown previously to be inhibited by combinations of T cells and NK cells according to HLA and KIR haplotype. Here the authors consider a combination of KIR2DL2+ NK and HLA-C*1...
www.nature.com
November 10, 2025 at 1:44 PM
Molecular basis for selection and inhibition of #HIV escape virus by T cells and KIR2DL2+NK cells www.nature.com/articles/s41... (open access) @natcomms.nature.com
“It’s not just HIV anymore”: A qualitative exploration of health, research, community and mental health priorities of long-term survivors of #HIV in the United States www.tandfonline.com/doi/full/10.... (open access)
“It’s not just HIV anymore”: A qualitative exploration of health, research, community and mental health priorities of long-term survivors of HIV in the United States
Long-term survivors (LTS) of HIV are people diagnosed before the advent of highly active antiretroviral therapy in 1996 or who have lived with HIV for more than ten years. As they age, many experie...
www.tandfonline.com
November 10, 2025 at 1:39 PM
“It’s not just HIV anymore”: A qualitative exploration of health, research, community and mental health priorities of long-term survivors of #HIV in the United States www.tandfonline.com/doi/full/10.... (open access)
Envisioning a Multidisciplinary #HBV Cure Research Agenda link.springer.com/article/10.1... (open access) #hepatitisB
Envisioning a Multidisciplinary HBV Cure Research Agenda - Current HIV/AIDS Reports
Purpose of Review We examine the current understanding of the multidisciplinary aspects of hepatitis B cure research, such as socio-behavioral sciences, ethics, community engagement, and translational...
link.springer.com
November 10, 2025 at 1:38 PM
Envisioning a Multidisciplinary #HBV Cure Research Agenda link.springer.com/article/10.1... (open access) #hepatitisB
Resistance Analysis of Low-Level Virologic Rebound During #HIV Treatment with Lenacapavir and Broadly Neutralizing Antibodies Teropavimab and Zinlirvimab academic.oup.com/jid/advance-... (open access) @jidjournal.bsky.social
Resistance Analysis of Low-Level Virologic Rebound During HIV-1 Treatment with Lenacapavir and Broadly Neutralizing Antibodies Teropavimab and Zinlirvimab
Resistance analysis from a Phase 1b study of lenacapavir with broadly neutralizing antibodies teropavimab and zinlirvimab showed rare emergent lenacapavir
academic.oup.com
November 10, 2025 at 1:33 PM
Resistance Analysis of Low-Level Virologic Rebound During #HIV Treatment with Lenacapavir and Broadly Neutralizing Antibodies Teropavimab and Zinlirvimab academic.oup.com/jid/advance-... (open access) @jidjournal.bsky.social
Estimation of prevention-effective CAB-LA concentrations among men who have sex with men (MSM) and transgender women (TGW) in HPTN 083 academic.oup.com/jid/advance-... (open access) #HIV #PrEP
Estimation of prevention-effective CAB-LA concentrations among men who have sex with men (MSM) and transgender women (TGW) in HPTN 083
This nested case-control study among participants in the HPTN 083 trial found that maintaining consistent plasma Cabotegravir concentrations ≥4x PA-IC90 (0
academic.oup.com
November 10, 2025 at 1:31 PM
Estimation of prevention-effective CAB-LA concentrations among men who have sex with men (MSM) and transgender women (TGW) in HPTN 083 academic.oup.com/jid/advance-... (open access) #HIV #PrEP
Changes in #HIV Reservoir Dynamics After Mpox Infection onlinelibrary.wiley.com/doi/10.1002/... (open access)
Changes in HIV‐1 Reservoir Dynamics After Mpox Infection
In May 2022, a large outbreak of monkeypox virus (MPXV) occurred in several non-endemic regions worldwide. Another outbreak in 2024 raised global concerns, particularly for immunocompromised individu....
onlinelibrary.wiley.com
November 10, 2025 at 1:24 PM
Changes in #HIV Reservoir Dynamics After Mpox Infection onlinelibrary.wiley.com/doi/10.1002/... (open access)
Reposted by TAGHIVscience
People need to understand that Chicago is a preview, not a culmination.
I have been actively watching contracts and surge funding over the last few days and what I would say to my friends in Baltimore is “be absolutely ready, right now.”
ICE poised to ramp up raids in Baltimore by Thanksgiving
The Trump administration has rush-ordered infrastructure to conduct raids, abduct residents, and detain people for months.
open.substack.com
November 9, 2025 at 1:51 PM
People need to understand that Chicago is a preview, not a culmination.
Reposted by TAGHIVscience
We need you to help spread this word. Cases are from Aug through Nov 2025 and 10 states are involved thus far.
Special shoutout to our friends and colleagues at CDC and FDA who got this out quickly all while not being paid
www.cdc.gov/botulism/out...
Special shoutout to our friends and colleagues at CDC and FDA who got this out quickly all while not being paid
www.cdc.gov/botulism/out...
Infant Botulism Outbreak Linked to Infant Formula, November 2025
Details on an outbreak of infant botulism linked to infant formula, November 2025.
www.cdc.gov
November 9, 2025 at 5:11 PM
We need you to help spread this word. Cases are from Aug through Nov 2025 and 10 states are involved thus far.
Special shoutout to our friends and colleagues at CDC and FDA who got this out quickly all while not being paid
www.cdc.gov/botulism/out...
Special shoutout to our friends and colleagues at CDC and FDA who got this out quickly all while not being paid
www.cdc.gov/botulism/out...
Reposted by TAGHIVscience
1/ The US Government has quietly removed a memorial to Black soldiers who died in World War II from the Netherlands American Cemetery in Margraten, South Limburg. The move follows a complaint from the right-wing Heritage Foundation to the American Battle Monuments Commission. ⬇️
November 9, 2025 at 9:23 AM
1/ The US Government has quietly removed a memorial to Black soldiers who died in World War II from the Netherlands American Cemetery in Margraten, South Limburg. The move follows a complaint from the right-wing Heritage Foundation to the American Battle Monuments Commission. ⬇️
Reposted by TAGHIVscience
The Times interviewed dozens of migrant men sent to a prison in El Salvador by the Trump administration. Independent forensic analysts called the testimony credible and consistent and said the treatment met the U.N.’s definition of torture.
www.nytimes.com/2025/11/08/w...
www.nytimes.com/2025/11/08/w...
‘You Are All Terrorists’: Four Months in a Salvadoran Prison
www.nytimes.com
November 8, 2025 at 11:58 AM
The Times interviewed dozens of migrant men sent to a prison in El Salvador by the Trump administration. Independent forensic analysts called the testimony credible and consistent and said the treatment met the U.N.’s definition of torture.
www.nytimes.com/2025/11/08/w...
www.nytimes.com/2025/11/08/w...
Reposted by TAGHIVscience
He has now erased fully 10% of the term to which Grijalva was elected.
Speaker Johnson is officially keeping the House in recess again next week. This will be the eighth consecutive week the House has been out of session. The chamber hasn't met since Sept. 19. Adelita Grijalva, who was elected on Sept. 23, has not been sworn in.
November 7, 2025 at 7:44 PM
He has now erased fully 10% of the term to which Grijalva was elected.
Reposted by TAGHIVscience
"While the CDC website lists 12 active workgroups ...an HHS spokesperson did not directly answer questions from MedPage Today about whether those workgroups remain active or have meetings scheduled."
More about ACIP here #MedSky via @medpagetoday.com.
www.medpagetoday.com/infectiousdi...
More about ACIP here #MedSky via @medpagetoday.com.
www.medpagetoday.com/infectiousdi...
CDC Vaccine Panel Workgroups Question Their Fate
Many expert panels shaping vaccine policy haven't met in months, leaving members in the dark
www.medpagetoday.com
November 7, 2025 at 9:41 PM
"While the CDC website lists 12 active workgroups ...an HHS spokesperson did not directly answer questions from MedPage Today about whether those workgroups remain active or have meetings scheduled."
More about ACIP here #MedSky via @medpagetoday.com.
www.medpagetoday.com/infectiousdi...
More about ACIP here #MedSky via @medpagetoday.com.
www.medpagetoday.com/infectiousdi...
Reposted by TAGHIVscience
Woaw, big news. Good news.
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
NIH under Trump wanted to slash indirect research costs to 15%. Pitt just signed an agreement at 59%
Pitt and the Department of Health and Human Services have agreed to maintain the school’s current 59% reimbursement rate for ancillary research costs through 2029.
www.wesa.fm
November 7, 2025 at 4:06 PM
Woaw, big news. Good news.
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
Thanks @sthilaire.bsky.social for the Intel
@wesa.fm
www.wesa.fm/health-scien...
Reposted by TAGHIVscience
What an incredible honor it was to host the Inaugural Paul Farmer Lecture and Award for Global Health Equity @mcgill.ca yesterday!
Mr Zackie Achmat received the award from Ms Catherine Bertrand Farmer
www.youtube.com/live/a6JOnJ0...
Mr Zackie Achmat received the award from Ms Catherine Bertrand Farmer
www.youtube.com/live/a6JOnJ0...
November 7, 2025 at 7:27 PM
What an incredible honor it was to host the Inaugural Paul Farmer Lecture and Award for Global Health Equity @mcgill.ca yesterday!
Mr Zackie Achmat received the award from Ms Catherine Bertrand Farmer
www.youtube.com/live/a6JOnJ0...
Mr Zackie Achmat received the award from Ms Catherine Bertrand Farmer
www.youtube.com/live/a6JOnJ0...
Reposted by TAGHIVscience
In #Budget2025, Canada describes $2.7 billion in cuts to international assistance as “savings.”
But let’s be clear Mark Carney: aid cuts aren’t savings.
They cost people's lives: https://ow.ly/iGPq50XoytN #cdnpoli
But let’s be clear Mark Carney: aid cuts aren’t savings.
They cost people's lives: https://ow.ly/iGPq50XoytN #cdnpoli
November 7, 2025 at 6:10 PM
In #Budget2025, Canada describes $2.7 billion in cuts to international assistance as “savings.”
But let’s be clear Mark Carney: aid cuts aren’t savings.
They cost people's lives: https://ow.ly/iGPq50XoytN #cdnpoli
But let’s be clear Mark Carney: aid cuts aren’t savings.
They cost people's lives: https://ow.ly/iGPq50XoytN #cdnpoli