STY
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syip.bsky.social
STY
@syip.bsky.social
UBC/MGH, 2/3 NSx, glass+genomics. VGH NP & Director of Clinical Genomics at BC Cancer. No to AK47 #Neuropathology #Molecularpathology #Genomics #AIpathology
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How many more kids must I accidentally murder before you realise it's deliberate?
November 20, 2025 at 8:17 PM
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No clear evidence to support any link between maternal acetaminophen (Tylenol) intake and autism or ADHD in offspring, a new umbrella, systematic review
@bmj.com
November 10, 2025 at 12:19 AM
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Legislative election hopeful Vivian Kong sees a rocky start to her political career as public sentiment towards the ex-Olympic champion changed drastically. Meanwhile, broadcaster TVB may face legal action from Japanese chain Sushiro. In full: buff.ly/s2wSm85
Backlash of 'smiling fencing queen' Vivian Kong, TVB's sushi row
Legislative election hopeful Vivian Kong sees a rocky start to her political career as public sentiment towards the ex-Olympic champion changed drastically. Meanwhile, broadcaster TVB may face legal action...
buff.ly
November 8, 2025 at 1:00 AM
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The pariah formerly known as Prince
October 30, 2025 at 7:26 PM
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The sequel to We Want Them Infected is done!

COVID killed 1.2 million Americans while vaccines saved millions.

Yet, disinformation superspreaders were empowered, where they are taking a wrecking ball to science & medicine.

How did that happen?🧵

sciencebasedmedicine.org/everyone-els...
Everyone Else is Lying to You: My Book is Done!
The pandemic’s biggest disinformation superspreaders are now in charge. How did this happen?
sciencebasedmedicine.org
October 3, 2025 at 6:57 PM
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#ICOM & some of our members just published an article investigating the prevalence & prognostic association of #TERT expression in #meningiomas, with implications for diagnosis & treatment: bit.ly/4g8L0LZ

@gelarehzadeh.bsky.social @justinzwang.bsky.social @felixehretmd.bsky.social @syip.bsky.social
September 3, 2025 at 10:26 AM
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Science is at the breaking point. With funding up in the air, labs are freezing hires and canceling plans. Innovation can’t wait. Read more in #TPhysMag: ow.ly/MZaL50WBucw @darachadwick.bsky.social 🧪
August 20, 2025 at 1:00 PM
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I think everyone needs this reminder. 🧪
June 27, 2025 at 8:59 PM
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🧠 A recent article on glioblastoma-instructed astrocytes suppressing tumour-specific T cell immunity is now available in @nature.com. 📖 Full article: www.nature.com/articles/s41...
#EANOessentials #NeuroOncology #Glioma #ImmunoOncology
Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity - Nature
A population of TRAIL-positive astrocytes in glioblastoma contributes to an immunosuppressive tumour microenvironment and this mechanism can be targeted with an engineered oncolytic virus to improve o...
www.nature.com
June 13, 2025 at 1:57 PM
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InterpolaAI, based on deep learning-based optical flow, restores and interpolates sparse image stacks.

This first example is a stack of histological images of a human pancreatic duct.

6 out of 7 images were missing or defective, all now generated.

Download here: www.nature.com/articles/s41...
June 7, 2025 at 5:43 PM
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"Gold standard science"
May 31, 2025 at 3:00 PM
May 24, 2025 at 5:05 PM
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So excited to share our latest work with @saratchandarlapaty.bsky.social, Antonio Marra, Andrea Gazzo @mskcancercenter.bsky.social out today in @natgenet.nature.com! We uncover the function and mechanism of APOBEC3-driven therapy resistance in breast cancer. 🧵 1/
www.nature.com/articles/s41...
APOBEC3 mutagenesis drives therapy resistance in breast cancer - Nature Genetics
Analysis of a large cohort of metastatic breast cancer samples shows that APOBEC mutational signatures are enriched in post-treatment samples. APOBEC activity was also associated with mutations known ...
www.nature.com
May 16, 2025 at 12:01 PM
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Earth, Wind & Friar
Name this album cover
May 13, 2025 at 1:59 PM
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A study in Scientific Reports shows that the dog-human relationship exhibits characteristics of both child and best friend relationships, combining the positive aspects of the parent-child bond with the minimal negative interactions of close friendships. go.nature.com/4cJtdcs 🧪
May 3, 2025 at 1:29 AM
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Both clonal hematopoiesis of indeterminate potential (CHIP) and cancer are more common with age. When they coexist in the same patient, CHIP cells may migrate to the tumor and have an adverse effect on overall survival. Full study results: nej.md/3EnzMVu

#MedSky #Hematology
April 27, 2025 at 1:21 PM
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Oh my God, this really is Hegseth.
Big time Stripes energy.
April 25, 2025 at 11:54 AM
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New evidence @nejm.org today that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Clonal Hematopoiesis as a Driver of Solid Tumors | NEJM
Clonal hematopoiesis is the expansion of a genetically related population of hematopoietic stem and progenitor cells that disproportionately contribute to blood-cell production.1 Clonal hematopoies...
www.nejm.org
April 23, 2025 at 10:22 PM
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When you scan the email from the editor and spot the words "accepted in principle"
April 19, 2025 at 1:51 PM
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This new report by several ICOM authors in JAMA Oncology highlights the importance of a role for #CytogeneticProfiling in the next iteration of #CNS WHO grading.

Read the full report now: bit.ly/3EmWNb2

@gelarehzadeh.bsky.social @justinzwang.bsky.social
April 18, 2025 at 10:37 AM
April 10, 2025 at 1:42 AM
April 8, 2025 at 4:14 AM