Stephen Barclay
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stephentbarclay.bsky.social
Stephen Barclay
@stephentbarclay.bsky.social
Consultant Gastroenterologist, Glasgow Royal Infirmary - interested in all things liver. Liversky, Livertwitter
Reposted by Stephen Barclay
First first author article for Eemeli Puhakka published!

We identified a profile of metabolites separating those with early stage progressive alcohol-related liver disease from non-progressive alcohol-related liver disease using metabolomics

doi.org/10.1111/liv....

#metabolomics #alcohol
Serum Metabolite Profile in Progressive Versus Nonprogressive Alcohol‐Related Liver Disease: A Cross‐Sectional Metabolomics Study
Background and Aims Alcohol-related liver disease (ALD) is a major cause of mortality and disability-adjusted life years. It is not fully understood why a small proportion of patients develop progre...
doi.org
May 14, 2025 at 7:10 PM
Merry Christmas to all on #liversky
December 25, 2024 at 10:25 PM
Emails this evening between colleagues in Scotland about HCC surveillance in HBV patients from Sub-Saharan Africa, many performing surveillance at a young age but questioning need (if no advanced fibrosis) in light of pubmed.ncbi.nlm.nih.gov/37898348/ what are others doing? #liversky #hepsky
Hepatocellular carcinoma risk in sub-Saharan African and Afro-Surinamese individuals with chronic hepatitis B living in Europe - PubMed
Sub-Saharan African ethnicity has been associated with a higher risk of hepatocellular carcinoma among individuals with chronic hepatitis B. In this international multicenter cohort study of sub-Sahar...
pubmed.ncbi.nlm.nih.gov
December 2, 2024 at 9:19 PM
Reposted by Stephen Barclay
New people added to the PSC Starter Pack
go.bsky.app/6hLJsJT

Help PSC researchers to connect. Who should be added?
November 27, 2024 at 10:46 PM
Reposted by Stephen Barclay
www.bbc.com/news/article...

Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today!

#LiverSky
@adhanda.bsky.social
@aleksanderkrag.bsky.social
‘At 31, I was told if I didn’t stop drinking, I could die’
BBC journalist Hazel Martin was told she had liver fibrosis and must go teetotal or she could die.
www.bbc.com
November 25, 2024 at 6:47 AM
Reposted by Stephen Barclay
Very excited to be on @bbcnews-uk-rss.bsky.social Panorama tomorrow, talking about the hidden harms of binge drinking @stsucl.bsky.social #alcohol #livertwitter #PublicHealth
November 24, 2024 at 8:52 PM
Reposted by Stephen Barclay
Pleased to see the publication of our paper showing effective management of alcohol withdrawal syndrome in patients with coexistent alcohol-related liver disease using GMAWS.
Great contributions by our medical students: Stroma Harcombe, Lujine Ibrahim, Georgia Smith and Alex Doyle.
t.co/fEjeZChSVI
November 20, 2024 at 2:10 PM
Reposted by Stephen Barclay
Share your best blue sky photo from your phone
November 18, 2024 at 12:36 AM
Reposted by Stephen Barclay
Yes!
And low qHBsAg patients are not the majority in our clinics… many left behind
November 19, 2024 at 6:58 PM
Reflecting on the raft of early phase HBV trials at #TLM24. Good to see new compounds with different MOAs moving forward- however so many of the inclusion criteria were for subjects with low qHBsAg who would have a good chance of S loss with just stopping their NA 🤷🏻‍♂️ #liversky
November 19, 2024 at 6:56 PM
Reposted by Stephen Barclay
Excellent study: the 40mg prednisolone for 28 days has been ripe for challenging for a long time now. Dose and duration established only by historical quirk rather than evidence. Need to assess targeted (I would argue NLR rather than severity based) tapered/short duration treatment.
#liversky
November 19, 2024 at 11:09 AM
Great to see real world data for GLP1 agonists in MASLD/MASh from the TARGET-NASH Cohort. 10% of cohort received > 1 year. Non users 1.69 RR of decompensation and 2.38 RR all cause mortality #liversky #tlm24
November 17, 2024 at 4:37 PM
Reposted by Stephen Barclay
Just updated

Keep it coming
Sharing #gisky and #liversky

Will add to it by end of day

Let me know and I will update

go.bsky.app/8Pho2tp
November 11, 2024 at 7:59 PM
Reposted by Stephen Barclay
October 13, 2023 at 7:46 PM
Glad to be on #medsky - any refugees from #livertwitter made it across yet?
October 13, 2023 at 10:28 PM