Kate Coldwell
@katecoldwell.bsky.social
Gut-liver axis in primary sclerosing cholangitis. 💩🦠🧪
PSC Starter Pack https://go.bsky.app/6hLJsJT
@daphnejacksontr.bsky.social Research Fellow, Uni of Oxford
#researchreturner
Girlguiding volunteer
https://linktr.ee/KateColdwell
PSC Starter Pack https://go.bsky.app/6hLJsJT
@daphnejacksontr.bsky.social Research Fellow, Uni of Oxford
#researchreturner
Girlguiding volunteer
https://linktr.ee/KateColdwell
Pinned
Kate Coldwell
@katecoldwell.bsky.social
· Nov 15
DYNAMHIX in PSC
We aim to characterise markers of liver function, intestinal inflammation and microbial metabolism over time in a cohort of patients with primary sclerosing cholangitis (PSC) and/or ulcerative colitis...
www.kennedy.ox.ac.uk
Intro to our #PSC #liversky #microbiome research 🧵 with
@nickilott.bsky.social
Primary sclerosing cholangitis (PSC) and the gut-liver axis.
PSC=blocked bile ducts --> liver damage ☹️ and unhappy guts ☹️²
75% with PSC also have ulcerative colitis ☹️³
1/n
@nickilott.bsky.social
Primary sclerosing cholangitis (PSC) and the gut-liver axis.
PSC=blocked bile ducts --> liver damage ☹️ and unhappy guts ☹️²
75% with PSC also have ulcerative colitis ☹️³
1/n
Reposted by Kate Coldwell
Unbelievable! How can this crap still be published?
Reverse Image Forensics Challenge: Try to find a unique area in Figure 9 of this recent Scientific Reports paper: 10.1038/s41598-025-17456-6 [Aug 2025] - Annotated by ImageTwin.ai
November 11, 2025 at 4:22 AM
Unbelievable! How can this crap still be published?
On my way to the @daphnejacksontr.bsky.social Fellows meeting in York today.
Looking forward to being surrounded by #researchreturners and our supporters.
Check out the Daphne Jackson Starter Pack go.bsky.app/H7CNqBF
Looking forward to being surrounded by #researchreturners and our supporters.
Check out the Daphne Jackson Starter Pack go.bsky.app/H7CNqBF
November 11, 2025 at 7:50 AM
On my way to the @daphnejacksontr.bsky.social Fellows meeting in York today.
Looking forward to being surrounded by #researchreturners and our supporters.
Check out the Daphne Jackson Starter Pack go.bsky.app/H7CNqBF
Looking forward to being surrounded by #researchreturners and our supporters.
Check out the Daphne Jackson Starter Pack go.bsky.app/H7CNqBF
Follow up poo question from a #PooTrivia quizzer:
what happened if wombats got constipated please. Do they produce much smaller, square cubes? Does they poo stop being cubes and become sperical or longer? Is this not an issue for wombats, due to their diet?
what happened if wombats got constipated please. Do they produce much smaller, square cubes? Does they poo stop being cubes and become sperical or longer? Is this not an issue for wombats, due to their diet?
#PooTriviaQuiz is coming up for #BiologyWeek
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
November 6, 2025 at 3:56 PM
Follow up poo question from a #PooTrivia quizzer:
what happened if wombats got constipated please. Do they produce much smaller, square cubes? Does they poo stop being cubes and become sperical or longer? Is this not an issue for wombats, due to their diet?
what happened if wombats got constipated please. Do they produce much smaller, square cubes? Does they poo stop being cubes and become sperical or longer? Is this not an issue for wombats, due to their diet?
Reposted by Kate Coldwell
Some pics from our annual lab autumn walk! We went to the lovely Blenheim palace to get some steps in & enjoy the autumn leaves🍁🚶♀️🌳
November 4, 2025 at 10:11 PM
Some pics from our annual lab autumn walk! We went to the lovely Blenheim palace to get some steps in & enjoy the autumn leaves🍁🚶♀️🌳
Reposted by Kate Coldwell
Interested in joining the Powrie Lab? We’re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. You’ll be part of our new MRC CoRE in Exposome Immunology!🧫🦠
Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
bulletin.ndorms.ox.ac.uk
October 29, 2025 at 8:55 PM
Interested in joining the Powrie Lab? We’re looking for a Postdoctoral Researcher to study the neutralisation capacity of human anti-IL-10 autoantibodies. You’ll be part of our new MRC CoRE in Exposome Immunology!🧫🦠
Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
Find out more here & apply by 11th Nov: bulletin.ndorms.ox.ac.uk/c/126QDJVBd0...
Reposted by Kate Coldwell
It’s #GlobalPSCAwarenessDay 💛
“Turning Hope Into Action” is this year’s theme, a powerful reminder that awareness is just the start. Real change happens every day.
Join us as we share inspiring #PSC stories from around the world 🌍
pscsupport.org.uk/global-psc-a...
#ELPA #LetsBeatPSC #PSCAwareness
“Turning Hope Into Action” is this year’s theme, a powerful reminder that awareness is just the start. Real change happens every day.
Join us as we share inspiring #PSC stories from around the world 🌍
pscsupport.org.uk/global-psc-a...
#ELPA #LetsBeatPSC #PSCAwareness
October 29, 2025 at 6:41 PM
It’s #GlobalPSCAwarenessDay 💛
“Turning Hope Into Action” is this year’s theme, a powerful reminder that awareness is just the start. Real change happens every day.
Join us as we share inspiring #PSC stories from around the world 🌍
pscsupport.org.uk/global-psc-a...
#ELPA #LetsBeatPSC #PSCAwareness
“Turning Hope Into Action” is this year’s theme, a powerful reminder that awareness is just the start. Real change happens every day.
Join us as we share inspiring #PSC stories from around the world 🌍
pscsupport.org.uk/global-psc-a...
#ELPA #LetsBeatPSC #PSCAwareness
Reposted by Kate Coldwell
“Although PSC is a difficult disease to have, it is also a time of great hope and optimism in the field.” Prof Hirschfield shares how collaboration between patients, doctors, and researchers worldwide is driving real progress and bringing new treatments closer than ever. #PSCAwarenessDay
October 29, 2025 at 11:03 AM
“Although PSC is a difficult disease to have, it is also a time of great hope and optimism in the field.” Prof Hirschfield shares how collaboration between patients, doctors, and researchers worldwide is driving real progress and bringing new treatments closer than ever. #PSCAwarenessDay
🌍🔬 Inspiring the next generation of scientists!
Check out Scientists in Schools - bringing #STEM professional into classrooms across the UK.
👉 Learn more or get involved: www.oibc.org.uk/educational-...
#STEM #ScienceEducation #ScientistsInSchools #FutureSTEM
Please share
Check out Scientists in Schools - bringing #STEM professional into classrooms across the UK.
👉 Learn more or get involved: www.oibc.org.uk/educational-...
#STEM #ScienceEducation #ScientistsInSchools #FutureSTEM
Please share
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
October 13, 2025 at 1:48 PM
🌍🔬 Inspiring the next generation of scientists!
Check out Scientists in Schools - bringing #STEM professional into classrooms across the UK.
👉 Learn more or get involved: www.oibc.org.uk/educational-...
#STEM #ScienceEducation #ScientistsInSchools #FutureSTEM
Please share
Check out Scientists in Schools - bringing #STEM professional into classrooms across the UK.
👉 Learn more or get involved: www.oibc.org.uk/educational-...
#STEM #ScienceEducation #ScientistsInSchools #FutureSTEM
Please share
Reposted by Kate Coldwell
Don't miss out on the fun! The #PooTriviaQuiz is happening this #BiologyWeek - a fun, free, family-friendly way to get people talking (and thinking) about their poo and digestive health!💚
Reserve your spot online below 👇
Reserve your spot online below 👇
#PooTriviaQuiz is coming up for #BiologyWeek
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
October 9, 2025 at 8:57 AM
Don't miss out on the fun! The #PooTriviaQuiz is happening this #BiologyWeek - a fun, free, family-friendly way to get people talking (and thinking) about their poo and digestive health!💚
Reserve your spot online below 👇
Reserve your spot online below 👇
Do you work on PSC or know people who do?
Hepatologists? Gastroenterologists? Very special scientists?
Get in touch to join the PSC Starter Pack.
We're a rare bunch, a bit like PSC, so let's connect and #letsbeatPSC
#primarysclerosingcholangitis
go.bsky.app/6hLJsJT
Hepatologists? Gastroenterologists? Very special scientists?
Get in touch to join the PSC Starter Pack.
We're a rare bunch, a bit like PSC, so let's connect and #letsbeatPSC
#primarysclerosingcholangitis
go.bsky.app/6hLJsJT
October 7, 2025 at 3:58 PM
Do you work on PSC or know people who do?
Hepatologists? Gastroenterologists? Very special scientists?
Get in touch to join the PSC Starter Pack.
We're a rare bunch, a bit like PSC, so let's connect and #letsbeatPSC
#primarysclerosingcholangitis
go.bsky.app/6hLJsJT
Hepatologists? Gastroenterologists? Very special scientists?
Get in touch to join the PSC Starter Pack.
We're a rare bunch, a bit like PSC, so let's connect and #letsbeatPSC
#primarysclerosingcholangitis
go.bsky.app/6hLJsJT
Reposted by Kate Coldwell
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
October 5, 2025 at 9:08 AM
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
Reposted by Kate Coldwell
Calling all families with science-enthused kids!
Our microbiome researchers are hosting a free online quiz all about poo. Learn facts about animal poos, and how our amazing digestive system works! 💩
Sign up below. 👇
Our microbiome researchers are hosting a free online quiz all about poo. Learn facts about animal poos, and how our amazing digestive system works! 💩
Sign up below. 👇
#PooTriviaQuiz is coming up for #BiologyWeek
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
September 18, 2025 at 10:48 AM
Calling all families with science-enthused kids!
Our microbiome researchers are hosting a free online quiz all about poo. Learn facts about animal poos, and how our amazing digestive system works! 💩
Sign up below. 👇
Our microbiome researchers are hosting a free online quiz all about poo. Learn facts about animal poos, and how our amazing digestive system works! 💩
Sign up below. 👇
Great to be hosted at the VUmc in Amsterdam for a #PSC meeting. It was a new experience to attend a small highly-specialised meeting. We are rare people who work on a rare disease!
So much interest in DYNAMHIX in PSC and the gut-liver axis.
#microbiome
#primarysclerosingcholangitis
#LetsBeatPSC
So much interest in DYNAMHIX in PSC and the gut-liver axis.
#microbiome
#primarysclerosingcholangitis
#LetsBeatPSC
September 30, 2025 at 10:26 AM
Great to be hosted at the VUmc in Amsterdam for a #PSC meeting. It was a new experience to attend a small highly-specialised meeting. We are rare people who work on a rare disease!
So much interest in DYNAMHIX in PSC and the gut-liver axis.
#microbiome
#primarysclerosingcholangitis
#LetsBeatPSC
So much interest in DYNAMHIX in PSC and the gut-liver axis.
#microbiome
#primarysclerosingcholangitis
#LetsBeatPSC
#PooTriviaQuiz is coming up for #BiologyWeek
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
September 15, 2025 at 9:37 PM
#PooTriviaQuiz is coming up for #BiologyWeek
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Sponsored by Wooclap - helps people teach and learn.
Register at pootriviaquiz.eventbrite.co.uk
It's free and family-friendly but you do need to register to reserve a space on the Zoom call.
Reposted by Kate Coldwell
Calling all RSB members! Don't forget to sign up to our next member-only event with @katecoldwell.bsky.social & learn about the links between the gut microbiome, gut health, & liver diseases!
📆 Weds 17 September, 12:30-13:30, online
Find out more & book your place: my.rsb.org.uk/item.php?eve...
📆 Weds 17 September, 12:30-13:30, online
Find out more & book your place: my.rsb.org.uk/item.php?eve...
August 25, 2025 at 8:51 AM
Calling all RSB members! Don't forget to sign up to our next member-only event with @katecoldwell.bsky.social & learn about the links between the gut microbiome, gut health, & liver diseases!
📆 Weds 17 September, 12:30-13:30, online
Find out more & book your place: my.rsb.org.uk/item.php?eve...
📆 Weds 17 September, 12:30-13:30, online
Find out more & book your place: my.rsb.org.uk/item.php?eve...
Reposted by Kate Coldwell
Easier said than done, but worth saying anyway: it’s important to keep an eye on your internal battery and take a meaningful break to recharge when you need it.
Full video buff.ly/WyQIlDp
#PSCFatigue #Fatigue #LetsBeatPSC #PSC #PSCExpert #PSCResearch
Full video buff.ly/WyQIlDp
#PSCFatigue #Fatigue #LetsBeatPSC #PSC #PSCExpert #PSCResearch
August 19, 2025 at 9:56 AM
Easier said than done, but worth saying anyway: it’s important to keep an eye on your internal battery and take a meaningful break to recharge when you need it.
Full video buff.ly/WyQIlDp
#PSCFatigue #Fatigue #LetsBeatPSC #PSC #PSCExpert #PSCResearch
Full video buff.ly/WyQIlDp
#PSCFatigue #Fatigue #LetsBeatPSC #PSC #PSCExpert #PSCResearch
Reposted by Kate Coldwell
We had a fab time running The Gut Florists stall at Green Man Festival! From talking all things microbiome, painting gut microbes, making bacterial pom-poms, or doing microbe word searches, we had something for everyone & loved chatting to you!🧫💐🦠🌼
@britsocimm.bsky.social
@greenmanfest.bsky.social
@britsocimm.bsky.social
@greenmanfest.bsky.social
August 18, 2025 at 8:47 AM
We had a fab time running The Gut Florists stall at Green Man Festival! From talking all things microbiome, painting gut microbes, making bacterial pom-poms, or doing microbe word searches, we had something for everyone & loved chatting to you!🧫💐🦠🌼
@britsocimm.bsky.social
@greenmanfest.bsky.social
@britsocimm.bsky.social
@greenmanfest.bsky.social
Reposted by Kate Coldwell
More people than ever in the UK are waiting for a life-saving organ transplant. For those living with PSC, there’s no cure or effective treatment. Nearly half will need a liver transplant. Register your decision with @NHSOrganDonor today. www.organdonation.nhs.uk
#WorldOrganDonationDay #LetsBeatPSC
#WorldOrganDonationDay #LetsBeatPSC
August 13, 2025 at 1:17 PM
More people than ever in the UK are waiting for a life-saving organ transplant. For those living with PSC, there’s no cure or effective treatment. Nearly half will need a liver transplant. Register your decision with @NHSOrganDonor today. www.organdonation.nhs.uk
#WorldOrganDonationDay #LetsBeatPSC
#WorldOrganDonationDay #LetsBeatPSC
Location in the digestive tract matters!
💩 microbiota ≠ duodenal microbiota
As our understanding of the effect of the #microbiome in #PSC grows, it beomes more nuanced.
#LetsBeatPSC
#primarysclerosingcholangitis
💩 microbiota ≠ duodenal microbiota
As our understanding of the effect of the #microbiome in #PSC grows, it beomes more nuanced.
#LetsBeatPSC
#primarysclerosingcholangitis
Reconsidering the microbial origins of primary sclerosing cholangitis and related autoimmune disorders: A case for the antro‐duodenal microbiome | Request PDF
Request PDF | On Aug 5, 2025, Richard Kellermayer and others published Reconsidering the microbial origins of primary sclerosing cholangitis and related autoimmune disorders: A case for the antro‐duod...
www.researchgate.net
August 12, 2025 at 8:43 AM
Location in the digestive tract matters!
💩 microbiota ≠ duodenal microbiota
As our understanding of the effect of the #microbiome in #PSC grows, it beomes more nuanced.
#LetsBeatPSC
#primarysclerosingcholangitis
💩 microbiota ≠ duodenal microbiota
As our understanding of the effect of the #microbiome in #PSC grows, it beomes more nuanced.
#LetsBeatPSC
#primarysclerosingcholangitis
A great oportunity for people with primary sclerosing cholangitis to participate in a faecal microbiome transplant study.
#microbiome
#FMT
#LetsBeatPSC
#microbiome
#FMT
#LetsBeatPSC
Transplanting 💩 as a treatment for PSC? Dr Trivedi and his team @unibirmingham.bsky.social continue to recruit participants for this important study. Could you take part?
➡️ pscsupport.org.uk/find-psc-res...
#LetsBeatPSC #FARGO #PSC #IBD #LetsBeatPSC #Colitis #Crohns @lifearc.bsky.social
➡️ pscsupport.org.uk/find-psc-res...
#LetsBeatPSC #FARGO #PSC #IBD #LetsBeatPSC #Colitis #Crohns @lifearc.bsky.social
August 8, 2025 at 8:46 AM
A great oportunity for people with primary sclerosing cholangitis to participate in a faecal microbiome transplant study.
#microbiome
#FMT
#LetsBeatPSC
#microbiome
#FMT
#LetsBeatPSC
August 5, 2025 at 2:53 PM
Reposted by Kate Coldwell
If you're a RSB member, don't miss our next member-only event on gut microbiome and the gut-liver axis with @katecoldwell.bsky.social MRSB.
📆 Wednesday 17 September, 12:30 to 13:30, online
Find out more and book your place: my.rsb.org.uk/item.php?eve...
📆 Wednesday 17 September, 12:30 to 13:30, online
Find out more and book your place: my.rsb.org.uk/item.php?eve...
July 28, 2025 at 7:57 AM
If you're a RSB member, don't miss our next member-only event on gut microbiome and the gut-liver axis with @katecoldwell.bsky.social MRSB.
📆 Wednesday 17 September, 12:30 to 13:30, online
Find out more and book your place: my.rsb.org.uk/item.php?eve...
📆 Wednesday 17 September, 12:30 to 13:30, online
Find out more and book your place: my.rsb.org.uk/item.php?eve...
Reposted by Kate Coldwell
Can’t make it to Essex? Don't like golf? Don't worry! You can buy raffle tickets from anywhere in the UK for a chance to win some TRULY amazing raffle prizes including a week’s stay in a stunning 3-bed, 3-bath villa at the Four Seasons Fairways in Portugal! #LetsBeatPSC
July 23, 2025 at 9:17 AM
Can’t make it to Essex? Don't like golf? Don't worry! You can buy raffle tickets from anywhere in the UK for a chance to win some TRULY amazing raffle prizes including a week’s stay in a stunning 3-bed, 3-bath villa at the Four Seasons Fairways in Portugal! #LetsBeatPSC
Reposted by Kate Coldwell
Some very exciting news to share!!
Huge news! A £50M MRC CoRE will bring together Manchester & Oxford to study how environmental exposures cause chronic inflammatory disease.
The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR.
www.kennedy.ox.ac.uk/news/new-ps5...
The CoRE will be Directed by Prof Judi Allen (Manchester) & co-Directed by Prof Dame Fiona Powrie, Director of the KIR.
www.kennedy.ox.ac.uk/news/new-ps5...
New £50m MRC Centre to study how environmental exposures cause chronic inflammatory diseases
A new Medical Research Council Centre of Research Excellence (MRC CoRE) will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases, such as asthma, ...
www.kennedy.ox.ac.uk
July 20, 2025 at 9:50 PM
Some very exciting news to share!!
Upcoming event - #Microbiome Innovation One Health Conference
15-16 September 2025 a the University of Oxford
Abstract deadline: 31 July
@kiroxford.bsky.social
tinyurl.com/MIOHC-2025
Please share
15-16 September 2025 a the University of Oxford
Abstract deadline: 31 July
@kiroxford.bsky.social
tinyurl.com/MIOHC-2025
Please share
July 21, 2025 at 9:36 AM