Stéphane Ory
@stephaneory.bsky.social
Researcher in cell biology at CNRS. Study mechanism of exocytosis and endocytosis in neurosecretory cells. Focus on the role of lipid scramblase, cytoskeleton and Rho GTPases.
Reposted by Stéphane Ory
Young researcher in membrane and organelle cell biology?
Join our hybrid half-day meeting in Paris this November !
~10 oral slots for PhDs & postdocs
Topics: endocytosis, exocytosis, organelles
Submit your abstract before slots are filled 👉 t.ly/ePAlT
#YoungScientists #CellBiology #HybridMeeting
Join our hybrid half-day meeting in Paris this November !
~10 oral slots for PhDs & postdocs
Topics: endocytosis, exocytosis, organelles
Submit your abstract before slots are filled 👉 t.ly/ePAlT
#YoungScientists #CellBiology #HybridMeeting
1/2 day hybrid meeting of the Club Exocytose-Endocytose - Institut de Psychiatrie et Neurosciences (IPNP), Paris
Speakers invités:
exoendo.org
October 9, 2025 at 5:35 PM
Young researcher in membrane and organelle cell biology?
Join our hybrid half-day meeting in Paris this November !
~10 oral slots for PhDs & postdocs
Topics: endocytosis, exocytosis, organelles
Submit your abstract before slots are filled 👉 t.ly/ePAlT
#YoungScientists #CellBiology #HybridMeeting
Join our hybrid half-day meeting in Paris this November !
~10 oral slots for PhDs & postdocs
Topics: endocytosis, exocytosis, organelles
Submit your abstract before slots are filled 👉 t.ly/ePAlT
#YoungScientists #CellBiology #HybridMeeting
Reposted by Stéphane Ory
New work in #ScienceTranslationalMedicine reveals how a drop in polyunsaturated fatty acids (PUFAs) and the enzyme ELOVL2 correlate with vision decline in aged mice—and shows that intravitreal supplementation of PUFAs can reverse vision loss and rejuvenate the retina. https://scim.ag/4pNNh3M
Retinal polyunsaturated fatty acid supplementation reverses aging-related vision decline in mice
Intravitreal delivery of an ELOVL2 product reduces age-related molecular changes in the retina and restores visual function.
scim.ag
September 29, 2025 at 6:00 PM
New work in #ScienceTranslationalMedicine reveals how a drop in polyunsaturated fatty acids (PUFAs) and the enzyme ELOVL2 correlate with vision decline in aged mice—and shows that intravitreal supplementation of PUFAs can reverse vision loss and rejuvenate the retina. https://scim.ag/4pNNh3M
Reposted by Stéphane Ory
Publications scientifiques - Club Exo Endo - Exocytose Endocytose
exoendo.org
August 1, 2025 at 12:10 PM
Reposted by Stéphane Ory
Reposted by Stéphane Ory
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
January 31, 2025 at 10:28 AM
It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density, which usually isn’t attainable. Lipid-CLEM brought to you by @mathilda95.bsky.social changes that.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Stéphane Ory
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
May 6, 2025 at 9:01 AM
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear. @pavelbarahtjan.bsky.social addresses this question: www.biorxiv.org/content/10.1...
Reposted by Stéphane Ory
Been thinking about biomembranes? Wondering what next decade of research will be?
Wonder no more: there's an awesome conference coming up in Copenhagen in July!!
From simulations to cells and everything in between.
5 days left to submit abstract - APPLY!
www.biophysics.org/blog/beyond-...
Wonder no more: there's an awesome conference coming up in Copenhagen in July!!
From simulations to cells and everything in between.
5 days left to submit abstract - APPLY!
www.biophysics.org/blog/beyond-...
Beyond Simple Models: The Consequences of Membrane Complexity in Living Systems - Copenhagen, Denmark 2025
Dear Colleagues,
We are excited to announce the Biophysical Society Thematic Meeting on Beyond Simple Models: The Consequences of Membrane Complexity in Living Systems. This meeting will be held in ...
www.biophysics.org
May 7, 2025 at 9:36 PM
Been thinking about biomembranes? Wondering what next decade of research will be?
Wonder no more: there's an awesome conference coming up in Copenhagen in July!!
From simulations to cells and everything in between.
5 days left to submit abstract - APPLY!
www.biophysics.org/blog/beyond-...
Wonder no more: there's an awesome conference coming up in Copenhagen in July!!
From simulations to cells and everything in between.
5 days left to submit abstract - APPLY!
www.biophysics.org/blog/beyond-...
Reposted by Stéphane Ory
On my way home after 3 days full of great talks and lively discussions at Fort-Mahon-Plage. Thank you @clubexo-endo.bsky.social community, I had a blast!
May 7, 2025 at 9:24 PM
On my way home after 3 days full of great talks and lively discussions at Fort-Mahon-Plage. Thank you @clubexo-endo.bsky.social community, I had a blast!
Reposted by Stéphane Ory
We look forward to meeting again in Paris for the half-day meeting in November and for the next meeting in May 2026, which should be held in Aussois (Savoie, France).
May 7, 2025 at 8:30 PM
We look forward to meeting again in Paris for the half-day meeting in November and for the next meeting in May 2026, which should be held in Aussois (Savoie, France).
Reposted by Stéphane Ory
The “family photo”. Thank you to all the participants who made this meeting so rich in science and exchange! Thanks to the organizers for the exceptional scientific program and the free time to discover the Baie de Somme. Do not hesitate to join the club!
May 7, 2025 at 8:23 PM
The “family photo”. Thank you to all the participants who made this meeting so rich in science and exchange! Thanks to the organizers for the exceptional scientific program and the free time to discover the Baie de Somme. Do not hesitate to join the club!
Reposted by Stéphane Ory
Congratulations to Julie Beaucousin and Andela Petrovic who won the best poster presentation awards !!
May 7, 2025 at 5:31 PM
Congratulations to Julie Beaucousin and Andela Petrovic who won the best poster presentation awards !!
Reposted by Stéphane Ory
To close the meeting, great talk of Juliane Da Graça, winner of the 2025 thesis prize, presented her work on the role of endosome-endoplasmic reticulum membrane contact sites in autophagy regulation in normal and cancer cells.
May 7, 2025 at 5:30 PM
To close the meeting, great talk of Juliane Da Graça, winner of the 2025 thesis prize, presented her work on the role of endosome-endoplasmic reticulum membrane contact sites in autophagy regulation in normal and cancer cells.
Reposted by Stéphane Ory
The prizes for best presentations went to Léa Ripoll for her work on adenylate cyclase and dopamine signalling in neurons and Quentin Frenger for his work on ATG16L1 and B cell antigen receptor trafficking. Congratulations !!
May 7, 2025 at 5:15 PM
The prizes for best presentations went to Léa Ripoll for her work on adenylate cyclase and dopamine signalling in neurons and Quentin Frenger for his work on ATG16L1 and B cell antigen receptor trafficking. Congratulations !!
Reposted by Stéphane Ory
Great talks these two last days, including Marc Bitoun (Institut de Myologie, Paris) as keynote speaker who showed impressive data on allele-specific silencing therapy for centronuclear myopathy due to dyn2 mutations.
May 7, 2025 at 4:43 PM
Great talks these two last days, including Marc Bitoun (Institut de Myologie, Paris) as keynote speaker who showed impressive data on allele-specific silencing therapy for centronuclear myopathy due to dyn2 mutations.
Reposted by Stéphane Ory
Both keynote speakers (Aylin Hanyaloglu, London and Sara Sigismund, Milan ) offered compelling insights into the spatial control of receptor trafficking and signaling dynamics, how cellular compartment and MCS shapes signaling outcomes. @cellbiology.bsky.social exoendo.org/evenement/27...
May 6, 2025 at 2:22 PM
Both keynote speakers (Aylin Hanyaloglu, London and Sara Sigismund, Milan ) offered compelling insights into the spatial control of receptor trafficking and signaling dynamics, how cellular compartment and MCS shapes signaling outcomes. @cellbiology.bsky.social exoendo.org/evenement/27...
Reposted by Stéphane Ory
The 27th Club Exo-Endo meeting has started at Fort-Mahon.
exoendo.org/evenement/27...
Nice place, nice talks and congratulation to young researchers who made great talks!!
exoendo.org/evenement/27...
Nice place, nice talks and congratulation to young researchers who made great talks!!
May 6, 2025 at 1:30 PM
The 27th Club Exo-Endo meeting has started at Fort-Mahon.
exoendo.org/evenement/27...
Nice place, nice talks and congratulation to young researchers who made great talks!!
exoendo.org/evenement/27...
Nice place, nice talks and congratulation to young researchers who made great talks!!
Reposted by Stéphane Ory
Une pour 1600 (12 millions d'élèves, 7700 infirmières)
April 25, 2025 at 9:24 AM
Une pour 1600 (12 millions d'élèves, 7700 infirmières)
Reposted by Stéphane Ory
#RésultatScientifique Une avancée vers une médecine de précision pour les tumeurs neuroendocrines de l’intestin grêle !
Des chercheurs identifient des sous-types moléculaires, ouvrant la voie à des traitements plus ciblés. 🧬
buff.ly/YFIRw88
Des chercheurs identifient des sous-types moléculaires, ouvrant la voie à des traitements plus ciblés. 🧬
buff.ly/YFIRw88
Vers une médecine de précision pour les tumeurs neuroendocrines de l’intestin grêle
Les tumeurs neuroendocrines de l’intestin grêle, tumeurs rares, ont longtemps été perçues et traitées comme une seule et même maladie.
www.insb.cnrs.fr
April 25, 2025 at 5:01 AM
#RésultatScientifique Une avancée vers une médecine de précision pour les tumeurs neuroendocrines de l’intestin grêle !
Des chercheurs identifient des sous-types moléculaires, ouvrant la voie à des traitements plus ciblés. 🧬
buff.ly/YFIRw88
Des chercheurs identifient des sous-types moléculaires, ouvrant la voie à des traitements plus ciblés. 🧬
buff.ly/YFIRw88
Reposted by Stéphane Ory
Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution, advancing spatially resolved multi-omics mapping.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
TEMI: tissue-expansion mass-spectrometry imaging - Nature Methods
Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution...
www.nature.com
April 24, 2025 at 6:57 PM
Tissue-expansion method compatible with mass-spectrometry imaging (TEMI) enables the profiling of lipids, metabolites, peptides, proteins, and N-glycans in complex tissues with high spatial resolution, advancing spatially resolved multi-omics mapping.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Stéphane Ory
This is really an amazing tool for neuroscientists🤩! Finally something actually working for human neurons🧠. Happy that I could contribute. Congratulations @forna.bsky.social!
Excited for our latest work! We developed nanobinders for the luminal domain of Synaptotagmin 1 (calcium sensor for synaptic vesicles). Thanks among others to @verstrekenlab.bsky.social @opazo.bsky.social @meunierlab.bsky.social @volkerhaucke-lab.bsky.social www.biorxiv.org/content/10.1...
Nanobinders for Synaptotagmin 1 enable the analysis of synaptic vesicle dynamics in rodent and human models.
Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes to be affected in neural diseases. Monitoring this process, and in particular synaptic vesicle recycl...
www.biorxiv.org
April 23, 2025 at 1:19 PM
This is really an amazing tool for neuroscientists🤩! Finally something actually working for human neurons🧠. Happy that I could contribute. Congratulations @forna.bsky.social!
Reposted by Stéphane Ory
A package of research papers from the MICrONS (Machine Intelligence from Cortical Networks) consortium in Nature and Nature Methods provides a detailed map of mouse brain cell structure and connections, offering insights into how they relate to activity in the mouse brain. 🧪
The MICrONS Project
An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation for discovering the computational bases of cortical circuits.
go.nature.com
April 20, 2025 at 1:11 AM
A package of research papers from the MICrONS (Machine Intelligence from Cortical Networks) consortium in Nature and Nature Methods provides a detailed map of mouse brain cell structure and connections, offering insights into how they relate to activity in the mouse brain. 🧪
Reposted by Stéphane Ory
Il serait salutaire que le gouvernement français choisisse également ses propres universités et ses propres enseignants-chercheurs, au lieu de les ponctionner et de les laisser au bord de la banqueroute.
Avoir des principes, c'est bien. Les appliquer à soi-même, c'est mieux.
Avoir des principes, c'est bien. Les appliquer à soi-même, c'est mieux.
Emmanuel Macron appelle les chercheurs internationaux à « choisir » la France et l’Europe, avec un « rendez-vous le 5 mai »
Emmanuel Macron appelle les chercheurs internationaux à « choisir » la France et l’Europe, avec un « rendez-vous le 5 mai »
Avant ce rendez-vous, une plateforme baptisée « Choose France for Science » a été lancée jeudi par le gouvernement. Il la présente comme « une première étape pour préparer l’accueil des chercheurs internationaux », alors que chercheurs et universités américaines sont dans le collimateur de l’administration Trump.
www.lemonde.fr
April 20, 2025 at 6:25 AM
Il serait salutaire que le gouvernement français choisisse également ses propres universités et ses propres enseignants-chercheurs, au lieu de les ponctionner et de les laisser au bord de la banqueroute.
Avoir des principes, c'est bien. Les appliquer à soi-même, c'est mieux.
Avoir des principes, c'est bien. Les appliquer à soi-même, c'est mieux.
Reposted by Stéphane Ory
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
April 9, 2025 at 2:32 PM
Did you know…
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...
It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳
For details, visit our website:
journals.biologists.com/jcs/pages/re...