Ellen Staedtler
@staedtleres.bsky.social
Pain researcher. Somewhat Anesthesiologist. Mother. Outdoor lover.
Reposted by Ellen Staedtler
This started as a small project in the lab to get our staining to be cleaner and evolved thanks to a lot of hard work by our very talented fellow Diana King who is now at UPenn doing her PhD. We’ve been sharing the device and all I can say is it works REALLY WELL.
www.jpain.org/article/S152...
www.jpain.org/article/S152...
Efficient removal of naturally-occurring lipofuscin autofluorescence in human nervous tissue using high-intensity white light.
Background autofluorescence is enhanced in human tissue relative to small animals
and presents a barrier to fully realizing the potential of novel multiplex methods
in human studies. In particular, li...
www.jpain.org
March 7, 2025 at 6:02 AM
This started as a small project in the lab to get our staining to be cleaner and evolved thanks to a lot of hard work by our very talented fellow Diana King who is now at UPenn doing her PhD. We’ve been sharing the device and all I can say is it works REALLY WELL.
www.jpain.org/article/S152...
www.jpain.org/article/S152...
Reposted by Ellen Staedtler
BOOM! Super cool stuff
🔬 Exciting discovery! We've been curious about the function of unique IBA1+ cell staining we observed around healthy human DRG neurons in the lab (indicated by red arrows). A new paper @cellpress.bsky.social finally provides some answers. Link: www.cell.com/cell/fulltex...
April 9, 2025 at 10:48 AM
BOOM! Super cool stuff
The first time I visited the US was actually a conference in New Orleans. I immediately fell in love with Cajun cuisine, and preparing Gumbo has been a source of comfort and joy since many years now. Luckily, my family loves it as much as me. Picture of Saturday's dish for your attention.
February 24, 2025 at 1:32 AM
The first time I visited the US was actually a conference in New Orleans. I immediately fell in love with Cajun cuisine, and preparing Gumbo has been a source of comfort and joy since many years now. Luckily, my family loves it as much as me. Picture of Saturday's dish for your attention.
Reposted by Ellen Staedtler
An update on non-pharmacological interventions for pain relief pdf.sciencedirectassets.com/776849/1-s2....
February 20, 2025 at 7:29 AM
An update on non-pharmacological interventions for pain relief pdf.sciencedirectassets.com/776849/1-s2....
Reposted by Ellen Staedtler
Reposted by Ellen Staedtler
Really nice article in NY Times Magazine on the staggering impact of chronic pain, the challenges of treating it, and the journey toward discovering better, non-opioid pain therapies. 🧠💊
#ChronicPain #PainManagement
@karapedsgastrodoc.bsky.social
@nytimes.com
www.nytimes.com/2025/01/12/m...
#ChronicPain #PainManagement
@karapedsgastrodoc.bsky.social
@nytimes.com
www.nytimes.com/2025/01/12/m...
Chronic Pain Afflicts Billions of People. It’s Time for a Revolution.
As many as two billion people suffer from it — including me. Can science finally bring us relief?
www.nytimes.com
January 14, 2025 at 3:16 PM
Really nice article in NY Times Magazine on the staggering impact of chronic pain, the challenges of treating it, and the journey toward discovering better, non-opioid pain therapies. 🧠💊
#ChronicPain #PainManagement
@karapedsgastrodoc.bsky.social
@nytimes.com
www.nytimes.com/2025/01/12/m...
#ChronicPain #PainManagement
@karapedsgastrodoc.bsky.social
@nytimes.com
www.nytimes.com/2025/01/12/m...
Excited about the NIH Clinical Center podcast "Discovering hope in science" that featured our work. Listen in!
www.cc.nih.gov/podcast
www.cc.nih.gov/podcast
www.cc.nih.gov
January 15, 2025 at 10:52 PM
Excited about the NIH Clinical Center podcast "Discovering hope in science" that featured our work. Listen in!
www.cc.nih.gov/podcast
www.cc.nih.gov/podcast
Reposted by Ellen Staedtler
A pretty good year for drug approvals in 2024 www.nature.com/articles/d41... but neurology lags behind recent trends for the year. Top of the list on what to look forward to in 2025 is Suzetrigine (VX-548) for acute (post surgical) pain in Jan!
2024 FDA approvals
The FDA approved 50 new therapeutics in 2024, with green lights for a novel schizophrenia drug, a first NASH medicine and much more.
www.nature.com
January 2, 2025 at 7:56 PM
A pretty good year for drug approvals in 2024 www.nature.com/articles/d41... but neurology lags behind recent trends for the year. Top of the list on what to look forward to in 2025 is Suzetrigine (VX-548) for acute (post surgical) pain in Jan!
Reposted by Ellen Staedtler
hubs.la/Q02_YmnR0 It is finally out! Yes!!! Huge Thanks to
@robgereau for the support and guidance. Congratulations to all the co-authors. @jgenphysiol.bsky.social
@robgereau for the support and guidance. Congratulations to all the co-authors. @jgenphysiol.bsky.social
Intrinsic adaptive plasticity in mouse and human sensory neurons | Journal of General Physiology | Rockefeller University Press
In this study, McIlvried, Del Rosario, and colleagues show that mechanisms of adaptive plasticity are engaged in mouse and human sensory neurons after sust
hubs.la
December 17, 2024 at 8:32 PM
hubs.la/Q02_YmnR0 It is finally out! Yes!!! Huge Thanks to
@robgereau for the support and guidance. Congratulations to all the co-authors. @jgenphysiol.bsky.social
@robgereau for the support and guidance. Congratulations to all the co-authors. @jgenphysiol.bsky.social
Happy Thanksgiving! Homemade food with friends. American staples, German Rotkraut, Chilean wine. It can hardly get better.
November 29, 2024 at 3:22 PM
Happy Thanksgiving! Homemade food with friends. American staples, German Rotkraut, Chilean wine. It can hardly get better.
Happy about all connections on this new platform, and using the opportunity to announce our paper from last month. We found molecular evidence for a substantial, clinically relevant differentiation of human C-nociceptors.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The μ-opioid receptor differentiates two distinct human nociceptive populations relevant to clinical pain
The shortfall in new analgesic agents is a major impediment to reducing reliance on opioid medications for control of severe pain. In both animals and…
www.sciencedirect.com
November 25, 2024 at 9:21 PM
Happy about all connections on this new platform, and using the opportunity to announce our paper from last month. We found molecular evidence for a substantial, clinically relevant differentiation of human C-nociceptors.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Ellen Staedtler
Yet another really cool #pain paper today, from Yenisel Cruz-Almeida and John Neubert - www.biorxiv.org/content/10.1... Brain Aging Among Individuals with Classical Trigeminal Neuralgia
Brain Aging Among Individuals with Classical Trigeminal Neuralgia
Trigeminal neuralgia (TN) is a complex orofacial neuropathic pain condition with limited understanding of underlying mechanisms and therapeutic options. Emerging evidence suggests the involvement of t...
www.biorxiv.org
November 15, 2024 at 1:10 AM
Yet another really cool #pain paper today, from Yenisel Cruz-Almeida and John Neubert - www.biorxiv.org/content/10.1... Brain Aging Among Individuals with Classical Trigeminal Neuralgia
Reposted by Ellen Staedtler
Hello new followers! We have positions available in my lab for one postdoc and 2-3 postbacs to start over the next year and lead studies on pain & emotion using high field MRI. Join us! www.nccih.nih.gov/about/jobs/p...
Postdoctoral Researcher Positions: Affective Neuroscience and Pain Lab
Dr. Lauren Atlas’s laboratory is recruiting up to two postdoctoral researchers with expertise in functional magnetic resonance imaging (fMRI) and affective science to join the Section on Affective Neu...
www.nccih.nih.gov
November 13, 2024 at 3:15 PM
Hello new followers! We have positions available in my lab for one postdoc and 2-3 postbacs to start over the next year and lead studies on pain & emotion using high field MRI. Join us! www.nccih.nih.gov/about/jobs/p...