Sofía Vieto
@sofivieto.bsky.social
PhD candidate @Yale in Andres Hidalgo's Lab.
Macrophages, metabolism & aging.
Costa Rican 🇨🇷
Macrophages, metabolism & aging.
Costa Rican 🇨🇷
Reposted by Sofía Vieto
I’m thrilled to introduce you to the NeuMap! our latest work in@nature.com. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour de force www.nature.com/articles/s41...
Architecture of the neutrophil compartment - Nature
Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and ...
www.nature.com
December 3, 2025 at 6:43 PM
I’m thrilled to introduce you to the NeuMap! our latest work in@nature.com. A global, comprehensive, single-cell transcriptional atlas of neutrophils across 47 biological conditions in human and mice. A real tour de force www.nature.com/articles/s41...
Reposted by Sofía Vieto
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
www.nature.com
July 17, 2025 at 11:28 AM
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Sofía Vieto
Several mammal species live in cold-water environments thanks to adaptations like blubber and large size. A notable exception is the sea otter—so how does it stay warm?
A 2021 Science study found an answer: skeletal muscle thermogenesis.
Learn more on #WorldOtterDay: scim.ag/4jjvMDL
A 2021 Science study found an answer: skeletal muscle thermogenesis.
Learn more on #WorldOtterDay: scim.ag/4jjvMDL
![Fig. 2 Whole-body estimates of sea otter metabolism scaled to body mass.
Estimated scaled whole-body metabolic rates include predicted [BMR; predicted on the basis of scaled rate for eutherian mammals], sea otter resting metabolic rate, and whole-body skeletal muscle leak capacity.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:vqgovau5gkirnk3ss5qwjdmz/bafkreifqng4uadol3gghmq6ktpvj5vksaptsqxdfvtenfsgubbfr2l6ani@jpeg)
May 28, 2025 at 6:28 PM
Several mammal species live in cold-water environments thanks to adaptations like blubber and large size. A notable exception is the sea otter—so how does it stay warm?
A 2021 Science study found an answer: skeletal muscle thermogenesis.
Learn more on #WorldOtterDay: scim.ag/4jjvMDL
A 2021 Science study found an answer: skeletal muscle thermogenesis.
Learn more on #WorldOtterDay: scim.ag/4jjvMDL
Reposted by Sofía Vieto
"Psychological safety" was the #1 predictor of an effective team in a study by Google. 'In other words, for a diverse team to work to its fullest capacity, everyone on the team must feel that it is safe to voice his or her opinions without being ridiculed.' 🙏@virusesimmunity.bsky.social
April 29, 2025 at 12:32 AM
"Psychological safety" was the #1 predictor of an effective team in a study by Google. 'In other words, for a diverse team to work to its fullest capacity, everyone on the team must feel that it is safe to voice his or her opinions without being ridiculed.' 🙏@virusesimmunity.bsky.social
Reposted by Sofía Vieto
Here's what is exciting about the science of aging
my op-ed @nytopinion.nytimes.com
as presented in depth in SUPER AGERS (out 6 May)
www.nytimes.com/2025/04/21/o...
my op-ed @nytopinion.nytimes.com
as presented in depth in SUPER AGERS (out 6 May)
www.nytimes.com/2025/04/21/o...
Opinion | How to Live Healthier for Longer (Gift Article)
A new era of medical care is upon us.
www.nytimes.com
April 21, 2025 at 2:03 PM
Here's what is exciting about the science of aging
my op-ed @nytopinion.nytimes.com
as presented in depth in SUPER AGERS (out 6 May)
www.nytimes.com/2025/04/21/o...
my op-ed @nytopinion.nytimes.com
as presented in depth in SUPER AGERS (out 6 May)
www.nytimes.com/2025/04/21/o...
Thanks for joining us @itaiyanai.bsky.social We had a great time hosting you! You really know how to engage an audience 🥳
Is there anything more fun than starting your talk with a walk-up song?! Thank you to the brilliant 3rd year Immunobiology PhD students at Yale who organized the '12th Yale Immunobiology Student Symposium' today. @sofivieto.bsky.social
April 17, 2025 at 2:34 AM
Thanks for joining us @itaiyanai.bsky.social We had a great time hosting you! You really know how to engage an audience 🥳
Don’t miss @alazozcan.bsky.social talking about neutrophils of the skin. She’s amazing!!
Super excited to present our recent publication at the #OBS seminar series next week! 🎉
Come join us to talk about the coolest cell in our immune system (#facts). See you there!
Come join us to talk about the coolest cell in our immune system (#facts). See you there!
OBS #Immunology Seminar
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
Neutrophils and regulation of skin physiology
📆 Thu, 10th April, 12 pm EDT/5 pm CET
🎙️ Speaker
@alazozcan.bsky.social @yalesph.bsky.social
@drusqui.bsky.social @cnic @nature.com
📣 Moderator
@eugecc.bsky.social
us02web.zoom.us/meeting/regi...
April 4, 2025 at 6:31 PM
Don’t miss @alazozcan.bsky.social talking about neutrophils of the skin. She’s amazing!!
Reposted by Sofía Vieto
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Opinion | The Uncertain Fate of the Young American Scientist (Gift Article)
Young researchers are choosing between staying in science and staying in the United States.
www.nytimes.com
April 4, 2025 at 7:32 AM
www.nytimes.com/2025/04/03/o...
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Really important piece to share widely. Too many Americans don’t know how severe a threat this Administration poses to our scientific infrastructure, global leadership, and health security
Reposted by Sofía Vieto
Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork!
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Matrix-producing neutrophils populate and shield the skin
Nature - A population of neutrophils in the skin produces extracellular matrix, providing a defence strategy by reinforcing the barrier properties of the skin and helping to block the entry of...
rdcu.be
March 19, 2025 at 9:28 PM
Excited to post for the first time to present our exciting new paper @Nature. The fruit of massive work by Tommaso Vicanolo, @alazozcan.bsky.social and Jackson Li, and our superb collaborators Laiguan and Stefan Uderhardt. True teamwork!
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Free link: rdcu.be/eeeA2
www.nature.com/articles/s41...
Reposted by Sofía Vieto
1/Excited to share our latest work in Cancer Discovery @theaacr.bsky.social. Led with #MiyaHugaboom and @kstreet.bsky.social, we show that the presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical responses to PD-1 blockade in #RCC: brnw.ch/21wQUU4
Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma
Abstract. Immune checkpoint inhibitors (ICI) targeting the PD-1 pathway have transformed treatment of advanced renal cell carcinoma (RCC), but mechanisms underlying therapeutic response remain largely...
brnw.ch
February 25, 2025 at 5:45 PM
1/Excited to share our latest work in Cancer Discovery @theaacr.bsky.social. Led with #MiyaHugaboom and @kstreet.bsky.social, we show that the presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical responses to PD-1 blockade in #RCC: brnw.ch/21wQUU4