Silvia Marino
@smarino0111.bsky.social
Professor of Neuropathology, Director Brain Tumour Research Centre, Blizard Institute, Queen Mary University of London
#brain #tumours #epigenetics #stemcells #models …ah yes and #hiking enthusiast #dog-lover
#brain #tumours #epigenetics #stemcells #models …ah yes and #hiking enthusiast #dog-lover
#GliomaClub25 off to a great start @cruk-cityoflondon.bsky.social @cruk-si.bsky.social exciting talks lively audience!
October 3, 2025 at 10:47 AM
#GliomaClub25 off to a great start @cruk-cityoflondon.bsky.social @cruk-si.bsky.social exciting talks lively audience!
Interested in cutting edge technologies to study malignant brain tumours? Check out this great @braintumourrsch.bsky.social funded #PhD opportunity to join my team @blizardinstitute.bsky.social @qmul.bsky.social
Leveraging brain organoids to dissect the contribution of the region-specific microenvironment to the growth of malignant brain tumours. at Queen Mary University of London on FindAPhD.com
PhD Project - Leveraging brain organoids to dissect the contribution of the region-specific microenvironment to the growth of malignant brain tumours. at Queen Mary University of London, listed on Fi...
www.findaphd.com
September 4, 2025 at 3:50 PM
Interested in cutting edge technologies to study malignant brain tumours? Check out this great @braintumourrsch.bsky.social funded #PhD opportunity to join my team @blizardinstitute.bsky.social @qmul.bsky.social
Delighted that our paper has been chosen for inclusion in this collection! Great collaboration with Claire Vinel and @raduzabet.bsky.social @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
A year of stem cell and developmental biology
In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms ...
www.nature.com
June 6, 2025 at 3:25 PM
Delighted that our paper has been chosen for inclusion in this collection! Great collaboration with Claire Vinel and @raduzabet.bsky.social @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
Excited to see this work out! Led by Sara and James, we modelled and validated glioblastoma recurrence after standard of care therapy; understanding recurrence is key for tackling glioblastoma. 🙏 @braintumourrsch.bsky.social @cruk-si.bsky.social @blizardinstitute.bsky.social @qmul.ac.uk
Don't miss this article by S. Lucchini, J. Nicholson, @smarino0111.bsky.social & colleagues @qmul.ac.uk 👉
A novel model of #glioblastoma recurrence to identify therapeutic vulnerabilities:
🗞️ doi.org/10.1038/s443...
Read also N&V by H. Miletic & @thomasdaubon.bsky.social : doi.org/10.1038/s443...
A novel model of #glioblastoma recurrence to identify therapeutic vulnerabilities:
🗞️ doi.org/10.1038/s443...
Read also N&V by H. Miletic & @thomasdaubon.bsky.social : doi.org/10.1038/s443...
April 29, 2025 at 10:07 AM
Excited to see this work out! Led by Sara and James, we modelled and validated glioblastoma recurrence after standard of care therapy; understanding recurrence is key for tackling glioblastoma. 🙏 @braintumourrsch.bsky.social @cruk-si.bsky.social @blizardinstitute.bsky.social @qmul.ac.uk
Last few days for applying…..don’t miss out on a great opportunity!
Interested in #epigenetics #genomewide #screen #glioblastoma #braintumours? Check out this exciting opportunity to join us @blizardinstitute.bsky.social @qmul.ac.uk
Postdoctoral Research Associate at Queen Mary University of London
Apply for the Postdoctoral Research Associate role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
www.jobs.ac.uk
March 14, 2025 at 2:49 PM
Last few days for applying…..don’t miss out on a great opportunity!
Interested in #epigenetics #genomewide #screen #glioblastoma #braintumours? Check out this exciting opportunity to join us @blizardinstitute.bsky.social @qmul.ac.uk
Postdoctoral Research Associate at Queen Mary University of London
Apply for the Postdoctoral Research Associate role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.
www.jobs.ac.uk
March 4, 2025 at 5:01 PM
Interested in #epigenetics #genomewide #screen #glioblastoma #braintumours? Check out this exciting opportunity to join us @blizardinstitute.bsky.social @qmul.ac.uk
Congrats to Sara Lucchini for her #PhD viva today; wonderful work on glioblastoma recurrence! Thx to examiners Ruman Rahman and John Marshall for great discussions! #proudPI @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
March 3, 2025 at 10:01 PM
Congrats to Sara Lucchini for her #PhD viva today; wonderful work on glioblastoma recurrence! Thx to examiners Ruman Rahman and John Marshall for great discussions! #proudPI @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
Excited to share our work #chromatin #remodelling #glioblastoma a wonderful collaboration with @raduzabet.bsky.social @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets
eur01.safelinks.protection.outlook.com
February 7, 2025 at 8:52 AM
Excited to share our work #chromatin #remodelling #glioblastoma a wonderful collaboration with @raduzabet.bsky.social @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
Great @lscn.bsky.social organoid workshop hosted by @blizardinstitute.bsky.social @qmulfmd.bsky.social lively audience exciting talks!
February 5, 2025 at 4:39 PM
Great @lscn.bsky.social organoid workshop hosted by @blizardinstitute.bsky.social @qmulfmd.bsky.social lively audience exciting talks!
Alexandra and Niamh presenting their #glioblastoma #highgradeglioma #noveltargets research at BNS Annual Meeting 2025 #PhD #proudPI @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
January 30, 2025 at 11:08 AM
Alexandra and Niamh presenting their #glioblastoma #highgradeglioma #noveltargets research at BNS Annual Meeting 2025 #PhD #proudPI @blizardinstitute.bsky.social @qmulfmd.bsky.social @braintumourrsch.bsky.social
Prestigious Alfred Meyer Memorial Lecture 2025 given by David Ellison @stjuderesearch.bsky.social at the BNS Annual Meeting #neuropathology #brain #tumours #childhood #cancer
January 29, 2025 at 4:23 PM
Prestigious Alfred Meyer Memorial Lecture 2025 given by David Ellison @stjuderesearch.bsky.social at the BNS Annual Meeting #neuropathology #brain #tumours #childhood #cancer
Reposted by Silvia Marino
One week left to get your applications in for this exciting PhD studentship fully-funded for students eligible for UK fees.
Deadline: 31st January 2025
www.findaphd.com/phds/project...
Deadline: 31st January 2025
www.findaphd.com/phds/project...
January 24, 2025 at 7:22 PM
One week left to get your applications in for this exciting PhD studentship fully-funded for students eligible for UK fees.
Deadline: 31st January 2025
www.findaphd.com/phds/project...
Deadline: 31st January 2025
www.findaphd.com/phds/project...
Reposted by Silvia Marino
In this Review, Tao et al. discuss the origins and heterogeneity of pediatric medulloblastoma, through the molecular lens of cerebellar development, for the advancement of disease modeling, treatment and outcomes. #OpenAccess
Learn more here:
➡️ tinyurl.com/gd351936
Learn more here:
➡️ tinyurl.com/gd351936
January 13, 2025 at 5:17 PM
In this Review, Tao et al. discuss the origins and heterogeneity of pediatric medulloblastoma, through the molecular lens of cerebellar development, for the advancement of disease modeling, treatment and outcomes. #OpenAccess
Learn more here:
➡️ tinyurl.com/gd351936
Learn more here:
➡️ tinyurl.com/gd351936
Reposted by Silvia Marino
A decade in, expansion microscopy is unlocking insights across biology and medicine
https://go.nature.com/4adlNgg
https://go.nature.com/4adlNgg
‘Expansion microscopy’ turns ten: how a tissue-swelling method brought super-resolution imaging to the masses
A decade in, expansion microscopy is unlocking insights across biology and medicine.
go.nature.com
January 13, 2025 at 5:54 PM
A decade in, expansion microscopy is unlocking insights across biology and medicine
https://go.nature.com/4adlNgg
https://go.nature.com/4adlNgg
Reposted by Silvia Marino
Something you don't see every day!
Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
www.cell.com/cell/fulltex...
open-access
Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
www.cell.com/cell/fulltex...
open-access
January 10, 2025 at 6:56 PM
Something you don't see every day!
Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
www.cell.com/cell/fulltex...
open-access
Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins
www.cell.com/cell/fulltex...
open-access
Reposted by Silvia Marino
A 2023 Review in #ScienceTranslationalMedicine looks at the complex connections between astrocytes and other types of cells in the nervous system, including neurons, oligodendrocytes, and microglia.
Learn more: https://scim.ag/40sLCpB #ScienceMagArchives
Learn more: https://scim.ag/40sLCpB #ScienceMagArchives
Neuroinflammation: An astrocyte perspective
The diverse roles of astrocytes and their cell-cell interactions in neurologic diseases offer opportunities for their therapeutic targeting.
scim.ag
January 11, 2025 at 3:07 PM
A 2023 Review in #ScienceTranslationalMedicine looks at the complex connections between astrocytes and other types of cells in the nervous system, including neurons, oligodendrocytes, and microglia.
Learn more: https://scim.ag/40sLCpB #ScienceMagArchives
Learn more: https://scim.ag/40sLCpB #ScienceMagArchives
Reposted by Silvia Marino
TFBSFootprinter: a multiomics tool for prediction of transcription factor binding sites in vertebrate species https://www.biorxiv.org/content/10.1101/2025.01.09.632105v1
January 12, 2025 at 9:47 AM
TFBSFootprinter: a multiomics tool for prediction of transcription factor binding sites in vertebrate species https://www.biorxiv.org/content/10.1101/2025.01.09.632105v1
January 12, 2025 at 5:17 PM
Reposted by Silvia Marino
Closing soon! 🚨
Are you an early career researcher in medicine and health?
Don't miss out on the chance to share your work with senior academics at our Clinical Academics in Training Annual Conference in Leeds this May #CATAC25
Submit your abstract by 13/1/25: ow.ly/lKi850UCALP
Are you an early career researcher in medicine and health?
Don't miss out on the chance to share your work with senior academics at our Clinical Academics in Training Annual Conference in Leeds this May #CATAC25
Submit your abstract by 13/1/25: ow.ly/lKi850UCALP
January 10, 2025 at 9:13 AM
Closing soon! 🚨
Are you an early career researcher in medicine and health?
Don't miss out on the chance to share your work with senior academics at our Clinical Academics in Training Annual Conference in Leeds this May #CATAC25
Submit your abstract by 13/1/25: ow.ly/lKi850UCALP
Are you an early career researcher in medicine and health?
Don't miss out on the chance to share your work with senior academics at our Clinical Academics in Training Annual Conference in Leeds this May #CATAC25
Submit your abstract by 13/1/25: ow.ly/lKi850UCALP
Reposted by Silvia Marino
Female scientists are quitting academic publishing earlier than their male counterparts, even in biological-science disciplines that have roughly equal representation.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Study of biologists quitting academia reveals hidden gender gaps
Even in fields in which women are well represented, they are up to 40% more likely than men to leave research within 20 years.
www.nature.com
January 10, 2025 at 10:21 AM
Female scientists are quitting academic publishing earlier than their male counterparts, even in biological-science disciplines that have roughly equal representation.
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Silvia Marino
Exciting news that @ukbiobank.bsky.social is launching a new project to measure up to 5,400 proteins in each of 600,000 samples from its participants. Last year, research by our Prof Claudia Langenberg and colleagues helped show how proteomic data can reveal new insights into disease.
January 10, 2025 at 1:09 PM
Exciting news that @ukbiobank.bsky.social is launching a new project to measure up to 5,400 proteins in each of 600,000 samples from its participants. Last year, research by our Prof Claudia Langenberg and colleagues helped show how proteomic data can reveal new insights into disease.
Reposted by Silvia Marino
news.ki.se/ms-brain-atl...
@annawilliamslab.bsky.social
@willmacnair.bsky.social
@deckardw.bsky.social
@karolinskainst.bsky.social
@edinburghuni.bsky.social
@cp-neuron.bsky.social
and many others....
@annawilliamslab.bsky.social
@willmacnair.bsky.social
@deckardw.bsky.social
@karolinskainst.bsky.social
@edinburghuni.bsky.social
@cp-neuron.bsky.social
and many others....
MS brain atlas could pave the way for personalised treatment
An international research team, including researchers at Karolinska Institutet, has mapped the genes expressed in the brain cells of people with multiple sclerosis (MS). The atlas, which is presented ...
news.ki.se
December 22, 2024 at 9:00 AM
Reposted by Silvia Marino
📢Still time to vote for the 2024 Development cover image of the year!
Of the 24 cover images featured in @dev-journal.bsky.social in 2024, which one is your favourite?
Browse through the images and vote by 13 Jan:
thenode.biologists.com/vote-for-the...
#DevBio 🧪
Of the 24 cover images featured in @dev-journal.bsky.social in 2024, which one is your favourite?
Browse through the images and vote by 13 Jan:
thenode.biologists.com/vote-for-the...
#DevBio 🧪
Vote for the 2024 Development cover image of the year - the Node
Over the past 12 months, Development has featured 24 cover images. Now, it's your chance to pick your favourite! To find out more about each cover image,
thenode.biologists.com
January 8, 2025 at 1:44 PM
📢Still time to vote for the 2024 Development cover image of the year!
Of the 24 cover images featured in @dev-journal.bsky.social in 2024, which one is your favourite?
Browse through the images and vote by 13 Jan:
thenode.biologists.com/vote-for-the...
#DevBio 🧪
Of the 24 cover images featured in @dev-journal.bsky.social in 2024, which one is your favourite?
Browse through the images and vote by 13 Jan:
thenode.biologists.com/vote-for-the...
#DevBio 🧪
Reposted by Silvia Marino
A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
A foundation model of transcription across human cell types - Nature
A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...
www.nature.com
January 8, 2025 at 4:27 PM
A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
Reposted by Silvia Marino
"[My adviser] told me that instead of focusing on finding a dream job, I should think about what I am good at and what makes me happy at least 80% of the time. This advice surprised me at first, but it ended up being exactly what I needed to hear." scim.ag/3DHtLCc
To choose a career, I needed to do more than ‘follow my dream’
Practical advice helped this international scientist figure out her post-Ph.D. direction
scim.ag
January 8, 2025 at 8:15 PM
"[My adviser] told me that instead of focusing on finding a dream job, I should think about what I am good at and what makes me happy at least 80% of the time. This advice surprised me at first, but it ended up being exactly what I needed to hear." scim.ag/3DHtLCc