Shivali Dongre
@shivalidongre.bsky.social
PhD student in the Vastenhouw lab @ UNIL!
Reposted by Shivali Dongre
Beyond excited to share our #NewPaper in @cellcellpress.bsky.social! Inflamed environments acidify intracellular #pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of #inflammation authors.elsevier.com/sd/article/S...
July 22, 2025 at 1:24 PM
Beyond excited to share our #NewPaper in @cellcellpress.bsky.social! Inflamed environments acidify intracellular #pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of #inflammation authors.elsevier.com/sd/article/S...
Reposted by Shivali Dongre
Another keynote speaker at #EDRC2025 is @mcgambetta.bsky.social from the Center for Integrative Genomics in Lausanne. Her research group is interested in the mechanisms of gene regulation, using #Drosophila as a model. Looking forward to her talk!
July 9, 2025 at 6:44 PM
Another keynote speaker at #EDRC2025 is @mcgambetta.bsky.social from the Center for Integrative Genomics in Lausanne. Her research group is interested in the mechanisms of gene regulation, using #Drosophila as a model. Looking forward to her talk!
Reposted by Shivali Dongre
Condensates change shape and consistency, they self-organize. @pombo.garcialab.bsky.social, @kallikappel @hymanlab.bsky.social, @brangwynnelab.bsky and others share how they explore condensate behavior in this story by @vivienm.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
July 3, 2025 at 3:41 PM
Condensates change shape and consistency, they self-organize. @pombo.garcialab.bsky.social, @kallikappel @hymanlab.bsky.social, @brangwynnelab.bsky and others share how they explore condensate behavior in this story by @vivienm.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Shivali Dongre
This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u
A short thread follows 1/n
A short thread follows 1/n
June 19, 2025 at 4:37 PM
This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u
A short thread follows 1/n
A short thread follows 1/n
Reposted by Shivali Dongre
90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
Omaya Dudin
Interview with Omaya Dudin, who uses Ichthyosporea as models to study how and why
unicellular organisms evolved multicellularity at the University of Geneva.
www.cell.com
June 10, 2025 at 9:41 AM
90% of you probably don’t need to read this.
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy.
It’s about sharing something hard to say out loud;
partly to heal, partly in case someone needs to hear it too. (1/3)
tinyurl.com/DudinO
Reposted by Shivali Dongre
Thanks for the shoot-out @zebrafishrock.bsky.social! This beautiful work by the Hnisz lab characterized a micropeptide (killswitch) and used it to probe condensates. This opens the door to assess the function of condensates and @shivalidongre.bsky.social did just that in our beloved fish embryo.
Contains a #zebrafish cameo from the @nvastenhouw.bsky.social Lab!
What controls condensate composition and function beyond binding stoichiometry? We show that condensate microenvironments play a key role, and can be probed by a micropeptide killswitch in live cells. www.nature.com/articles/s41... in @nature.com with @yaotianzhang.bsky.social Denes Hnisz & team.
June 5, 2025 at 8:35 PM
Thanks for the shoot-out @zebrafishrock.bsky.social! This beautiful work by the Hnisz lab characterized a micropeptide (killswitch) and used it to probe condensates. This opens the door to assess the function of condensates and @shivalidongre.bsky.social did just that in our beloved fish embryo.
Reposted by Shivali Dongre
Now published! Big congrats to first author @gginell.bsky.social
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
May 23, 2025 at 11:31 AM
Now published! Big congrats to first author @gginell.bsky.social
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...
We are actively working improving/updating various aspects of FINCHES; don't hesitate to reach out if you run into issues, have questions.
www.science.org/doi/10.1126/...