Synaptophilia
@shababhannan.bsky.social
Neuroscientist working on fruit flies, husband+pet dad full time, by night a chef mixing flavors, Liverpool football fan on weekends. I think about Alzheimer’s disease, synapses, mitochondria, lysosomes and ER.
Views are mine
Baylor College of Medicine
Views are mine
Baylor College of Medicine
We studied 100 fly orthologs of Alzheimer’s risk genes and found several crucial for CNS structure, function, or stress resilience and some also affecting Aβ and tau toxicity. www.biorxiv.org/content/10.1...
#Alzheimer's #Drosophila #brain #neurons
What gene would you follow up on from our results?
#Alzheimer's #Drosophila #brain #neurons
What gene would you follow up on from our results?
Revealing the nervous system requirements of Alzheimer’s disease risk genes in Drosophila
Most Alzheimer’s disease (AD) susceptibility genes have poorly understood roles in the central nervous system (CNS). To address this gap, we systematically characterized 100 conserved candidate AD ris...
www.biorxiv.org
August 17, 2025 at 1:20 AM
We studied 100 fly orthologs of Alzheimer’s risk genes and found several crucial for CNS structure, function, or stress resilience and some also affecting Aβ and tau toxicity. www.biorxiv.org/content/10.1...
#Alzheimer's #Drosophila #brain #neurons
What gene would you follow up on from our results?
#Alzheimer's #Drosophila #brain #neurons
What gene would you follow up on from our results?
Reposted by Synaptophilia
MassLive.com recently interviewed several Harvard FlyBase people and wrote this news article about the importance of FlyBase: tinyurl.com/4chpts9f
Why a database of bug genes could be one of Trump’s most devastating cuts at Harvard
FlyBase, the world's only fruit fly database, is in the crosshairs of Trump's attack on Harvard. Here's why it could matter for your health.
tinyurl.com
June 25, 2025 at 8:31 PM
MassLive.com recently interviewed several Harvard FlyBase people and wrote this news article about the importance of FlyBase: tinyurl.com/4chpts9f
Reposted by Synaptophilia
Hey #Drosophila folks - its #fivedays to go to sign up as #FlyCROSS #mentor 👀
If you're faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - fill up the mentor survey by July 14 to empower #earlycareer scientists in #Dros #community!
@flybase.bsky.social
If you're faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - fill up the mentor survey by July 14 to empower #earlycareer scientists in #Dros #community!
@flybase.bsky.social
Hey #Drosophila folks ! #FlyCROSS is back and #Mentor surveys are open NOW ! If you're a faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - we'd be delighted to have you as mentors to empower early career scientists in the #Dros community !
Summer 2025 Survey For Mentors : FlyCROSS Mentor Mentee Matching Program
We appreciate you taking the time and volunteering to be a mentor! Add dmelcross@gmail.com to your email address book or safe sender list, so that you can receive our emails. To be a participating me...
docs.google.com
July 9, 2025 at 2:48 PM
Hey #Drosophila folks - its #fivedays to go to sign up as #FlyCROSS #mentor 👀
If you're faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - fill up the mentor survey by July 14 to empower #earlycareer scientists in #Dros #community!
@flybase.bsky.social
If you're faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - fill up the mentor survey by July 14 to empower #earlycareer scientists in #Dros #community!
@flybase.bsky.social
Check out our new paper on #rare_neurological_diseases #undiagnosed_disease_network
#Spinocerebellar_ataxias
Our paper on RAB3A published in journal #brain shows a potential novel role for the gene in the context of rare neurological diseases.
academic.oup.com/brain/advanc...
#Spinocerebellar_ataxias
Our paper on RAB3A published in journal #brain shows a potential novel role for the gene in the context of rare neurological diseases.
academic.oup.com/brain/advanc...
Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism
Using an untargeted computational genetic association approach and classical linkage analysis, Hengel et al. identify RAB3A as a gene linked to autosomal d
academic.oup.com
April 9, 2025 at 7:15 PM
Check out our new paper on #rare_neurological_diseases #undiagnosed_disease_network
#Spinocerebellar_ataxias
Our paper on RAB3A published in journal #brain shows a potential novel role for the gene in the context of rare neurological diseases.
academic.oup.com/brain/advanc...
#Spinocerebellar_ataxias
Our paper on RAB3A published in journal #brain shows a potential novel role for the gene in the context of rare neurological diseases.
academic.oup.com/brain/advanc...
Paper alert. We highlight some recent papers published in our special research edition on mitochondria and neuro-developmental+degenerative diseases at Frontiers. #Mitochondria #Neurodegenerative_diseases #Frontiers_in_Neuroscience
www.frontiersin.org/articles/10....
www.frontiersin.org/articles/10....
Frontiers | Editorial: Molecular and cellular pathways leading to mitochondrial dysfunction and neurodegeneration: lessons from in vivo models, volume II
The second volume of our editorial is a continuation of the first (Hannan et al., 2022) and features two reviews and three research articles that highlight h...
www.frontiersin.org
January 30, 2025 at 5:37 PM
Paper alert. We highlight some recent papers published in our special research edition on mitochondria and neuro-developmental+degenerative diseases at Frontiers. #Mitochondria #Neurodegenerative_diseases #Frontiers_in_Neuroscience
www.frontiersin.org/articles/10....
www.frontiersin.org/articles/10....
Reposted by Synaptophilia
Another video of a developping drosophila embryo, but this time rotating. I beleive tjis was generated in Python using @maweigert.bsky.social 's spimagine rendering tool.
www.nature.com/articles/nbt...
🧪🔬🪰💻
www.nature.com/articles/nbt...
🧪🔬🪰💻
December 10, 2024 at 3:51 PM
Another video of a developping drosophila embryo, but this time rotating. I beleive tjis was generated in Python using @maweigert.bsky.social 's spimagine rendering tool.
www.nature.com/articles/nbt...
🧪🔬🪰💻
www.nature.com/articles/nbt...
🧪🔬🪰💻
Reposted by Synaptophilia
My mom got polio a couple of months before the vaccine got to Mexico. She passed her teenage years in bed and was only able to walk again for the uncountable hours her grandma spent giving her therapy. #vaccinesSafeLives
This was me in February 2017. I’ll keep marching for vaccines as long as I have to.
December 13, 2024 at 1:50 PM
My mom got polio a couple of months before the vaccine got to Mexico. She passed her teenage years in bed and was only able to walk again for the uncountable hours her grandma spent giving her therapy. #vaccinesSafeLives
Reposted by Synaptophilia
I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...
www.nytimes.com/2024/12/09/h...
December 9, 2024 at 11:19 PM
I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏
www.nytimes.com/2024/12/09/h...
www.nytimes.com/2024/12/09/h...
Reposted by Synaptophilia
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Implementation and validation of single-cell genomics experiments in neuroscience - Nature Neuroscience
Single-cell or single-nucleus RNA-sequencing experiments form a basis for biological insights about cell types and states, but they require orthogonal experiments to confirm the functional relevance o...
www.nature.com
December 6, 2024 at 6:38 PM
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper.
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Excited to contribute perturbation-based approaches.
www.nature.com/articles/s41...
Reposted by Synaptophilia
New review: together with PhD student Ciarán Butler-Hallissey, we provide a comprehensive overview on how super-resolution microscopy can dissect the neuronal cytoskeleton, and the exciting perspectives ahead. Shock full of beautiful images, published or from our lab! www.nature.com/articles/s44...
December 4, 2024 at 11:31 AM
New review: together with PhD student Ciarán Butler-Hallissey, we provide a comprehensive overview on how super-resolution microscopy can dissect the neuronal cytoskeleton, and the exciting perspectives ahead. Shock full of beautiful images, published or from our lab! www.nature.com/articles/s44...
Recently saw this while preparing some teaching material on the #History_of_Neuroscience. This is special. Here #Cajal is sharing his reaction after seeing neurons stained with the #Golgi_stain. #Cajal_and_Golgi had conflicting views about the structure of the neurons.
November 27, 2024 at 8:14 PM
Recently saw this while preparing some teaching material on the #History_of_Neuroscience. This is special. Here #Cajal is sharing his reaction after seeing neurons stained with the #Golgi_stain. #Cajal_and_Golgi had conflicting views about the structure of the neurons.
Reposted by Synaptophilia
Hello, Drosophila Community!
We’re excited to join Bluesky and connect with researchers! At the Drosophila Genomics Resource Center (DGRC), we provide reagents to power your discoveries.
Follow us for updates, tips, and discussions.
What’s your favorite #Drosophila research question? Let’s chat!
We’re excited to join Bluesky and connect with researchers! At the Drosophila Genomics Resource Center (DGRC), we provide reagents to power your discoveries.
Follow us for updates, tips, and discussions.
What’s your favorite #Drosophila research question? Let’s chat!
November 23, 2024 at 12:56 PM
Hello, Drosophila Community!
We’re excited to join Bluesky and connect with researchers! At the Drosophila Genomics Resource Center (DGRC), we provide reagents to power your discoveries.
Follow us for updates, tips, and discussions.
What’s your favorite #Drosophila research question? Let’s chat!
We’re excited to join Bluesky and connect with researchers! At the Drosophila Genomics Resource Center (DGRC), we provide reagents to power your discoveries.
Follow us for updates, tips, and discussions.
What’s your favorite #Drosophila research question? Let’s chat!
Hello #Drosophila scientists in Bluesky! Here’s a list of useful #Drosophila_resources #Drosophila_starterpack
I will keep sharing new resources as I find them!
bsky.app/profile/bdsc...
bsky.app/profile/flyb...
bsky.app/profile/dgrc...
bsky.app/profile/fly-...
bsky.app/profile/dros...
I will keep sharing new resources as I find them!
bsky.app/profile/bdsc...
bsky.app/profile/flyb...
bsky.app/profile/dgrc...
bsky.app/profile/fly-...
bsky.app/profile/dros...
November 26, 2024 at 5:20 PM
Hello #Drosophila scientists in Bluesky! Here’s a list of useful #Drosophila_resources #Drosophila_starterpack
I will keep sharing new resources as I find them!
bsky.app/profile/bdsc...
bsky.app/profile/flyb...
bsky.app/profile/dgrc...
bsky.app/profile/fly-...
bsky.app/profile/dros...
I will keep sharing new resources as I find them!
bsky.app/profile/bdsc...
bsky.app/profile/flyb...
bsky.app/profile/dgrc...
bsky.app/profile/fly-...
bsky.app/profile/dros...
Reposted by Synaptophilia
This week in Science Without Anguish: Who is driving our bus? The importance of controlling the controllables in research life.
www.sciencewithoutanguish.com/blog/who-is-...
www.sciencewithoutanguish.com/blog/who-is-...
November 25, 2024 at 12:37 PM
This week in Science Without Anguish: Who is driving our bus? The importance of controlling the controllables in research life.
www.sciencewithoutanguish.com/blog/who-is-...
www.sciencewithoutanguish.com/blog/who-is-...
Reposted by Synaptophilia
Hi #astrocyte lovers! We are organizing the third edition of #AstrocyteCafe online, with FREE monthly seminars starting from January 2025...and we are looking for speakers!
Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com 😍
Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com 😍
November 22, 2024 at 1:17 PM
Hi #astrocyte lovers! We are organizing the third edition of #AstrocyteCafe online, with FREE monthly seminars starting from January 2025...and we are looking for speakers!
Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com 😍
Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com 😍
Reposted by Synaptophilia
🧠 The NIA seeks your input on its draft Strategic Directions for Research 2026-2030! Shape the future of ageing research by sharing your feedback by 31 Jan 2025. Learn more and contribute:
www.dementiaresearcher.nihr.ac.uk/nia-strategi...
www.dementiaresearcher.nihr.ac.uk/nia-strategi...
November 25, 2024 at 12:22 PM
🧠 The NIA seeks your input on its draft Strategic Directions for Research 2026-2030! Shape the future of ageing research by sharing your feedback by 31 Jan 2025. Learn more and contribute:
www.dementiaresearcher.nihr.ac.uk/nia-strategi...
www.dementiaresearcher.nihr.ac.uk/nia-strategi...
Reposted by Synaptophilia
It’s disheartening to witness such short-sightedness from some…
November 25, 2024 at 7:40 PM
It’s disheartening to witness such short-sightedness from some…
If you are a Neuroscience faculty teaching undergraduates, this may be a useful resource: www.funfaculty.org
Faculty for Undergraduate Neuroscience
www.funfaculty.org
November 25, 2024 at 4:54 PM
If you are a Neuroscience faculty teaching undergraduates, this may be a useful resource: www.funfaculty.org
Reposted by Synaptophilia
Do you teach neuroscience? Here’s a list I’ve compiled of mostly free online neuroscience textbooks, simulations and datasets you can use for your course! If I’m missing something, let me know so I can add it! docs.google.com/document/d/1...
Free Neuroscience Textbooks and Online Tutorials
Free Neuroscience Textbooks and Online Tutorials (Compiled by Carlos Aizenman, Brown University, Dept. of Neuroscience) Maintaining a current list of digital educational resources is tricky. Softwar...
docs.google.com
November 20, 2024 at 8:08 PM
Do you teach neuroscience? Here’s a list I’ve compiled of mostly free online neuroscience textbooks, simulations and datasets you can use for your course! If I’m missing something, let me know so I can add it! docs.google.com/document/d/1...
Reposted by Synaptophilia
Looking for a PhD in Cognitive Science, Cognitive Neuroscience or related in Germany? One week left to apply for the Max Planck School of Cognition: cognition.maxplanckschools.org/en/application
#PsychSciSky #compneurosky #neuroskyence #NeuroAI #Neuroimaging
#PsychSciSky #compneurosky #neuroskyence #NeuroAI #Neuroimaging
November 24, 2024 at 10:12 AM
Looking for a PhD in Cognitive Science, Cognitive Neuroscience or related in Germany? One week left to apply for the Max Planck School of Cognition: cognition.maxplanckschools.org/en/application
#PsychSciSky #compneurosky #neuroskyence #NeuroAI #Neuroimaging
#PsychSciSky #compneurosky #neuroskyence #NeuroAI #Neuroimaging
Reposted by Synaptophilia
Registration is now open for 'CNS2025: Expanding the Horizons of Brain Research' at
neuroscience.cam.ac.uk/camneuro-eve...
Stellar Programme w/ plenaries from Soyon Hong & Mayank Mehta & @CamNeuro peeps from 7 departments
Sign up now to guarantee your space!
Sorry for the silence….will do better!
neuroscience.cam.ac.uk/camneuro-eve...
Stellar Programme w/ plenaries from Soyon Hong & Mayank Mehta & @CamNeuro peeps from 7 departments
Sign up now to guarantee your space!
Sorry for the silence….will do better!
November 19, 2024 at 7:06 PM
Registration is now open for 'CNS2025: Expanding the Horizons of Brain Research' at
neuroscience.cam.ac.uk/camneuro-eve...
Stellar Programme w/ plenaries from Soyon Hong & Mayank Mehta & @CamNeuro peeps from 7 departments
Sign up now to guarantee your space!
Sorry for the silence….will do better!
neuroscience.cam.ac.uk/camneuro-eve...
Stellar Programme w/ plenaries from Soyon Hong & Mayank Mehta & @CamNeuro peeps from 7 departments
Sign up now to guarantee your space!
Sorry for the silence….will do better!