Sayem Borhan, PhD
@sayemborhan.bsky.social
Assistant Professor | Biostatistician | Health Researcher
sayemborhan.com
sayemborhan.com
Reposted by Sayem Borhan, PhD
Reimagining Evidence: Artificial Intelligence Synthetic Data Generation for Cancer Research | JCO Clinical Cancer Informatics ascopubs.org/doi/full/10.... #JCOCCI
Reimagining Evidence: Artificial Intelligence Synthetic Data Generation for Cancer Research | JCO Clinical Cancer Informatics
ascopubs.org
November 19, 2025 at 5:55 PM
Reimagining Evidence: Artificial Intelligence Synthetic Data Generation for Cancer Research | JCO Clinical Cancer Informatics ascopubs.org/doi/full/10.... #JCOCCI
Reposted by Sayem Borhan, PhD
MIT book Introduction to Machine Learning Systems by Vijay Janapa Reddi:
• PDF www.mlsysbook.ai/assets/downl...
• EPUB www.mlsysbook.ai
Data Engineering
Model Development
Optimization
Deployment
Infrastructure
Monitoring
Security, Privacy, Safety
Scaling
Responsible AI
Future
• PDF www.mlsysbook.ai/assets/downl...
• EPUB www.mlsysbook.ai
Data Engineering
Model Development
Optimization
Deployment
Infrastructure
Monitoring
Security, Privacy, Safety
Scaling
Responsible AI
Future
November 16, 2025 at 10:07 AM
MIT book Introduction to Machine Learning Systems by Vijay Janapa Reddi:
• PDF www.mlsysbook.ai/assets/downl...
• EPUB www.mlsysbook.ai
Data Engineering
Model Development
Optimization
Deployment
Infrastructure
Monitoring
Security, Privacy, Safety
Scaling
Responsible AI
Future
• PDF www.mlsysbook.ai/assets/downl...
• EPUB www.mlsysbook.ai
Data Engineering
Model Development
Optimization
Deployment
Infrastructure
Monitoring
Security, Privacy, Safety
Scaling
Responsible AI
Future
Reposted by Sayem Borhan, PhD
Datasets, Benchmarks, and Protocols by L.G. McCoy et al.: Assessment of Large Language Models in Clinical Reasoning: A Novel Benchmarking Study nejm.ai/3KlD5yX
@liamgmccoy.bsky.social #AI #MedSky #MLSky
@liamgmccoy.bsky.social #AI #MedSky #MLSky
October 30, 2025 at 12:10 PM
Datasets, Benchmarks, and Protocols by L.G. McCoy et al.: Assessment of Large Language Models in Clinical Reasoning: A Novel Benchmarking Study nejm.ai/3KlD5yX
@liamgmccoy.bsky.social #AI #MedSky #MLSky
@liamgmccoy.bsky.social #AI #MedSky #MLSky
Reposted by Sayem Borhan, PhD
ICYMI: New online! Clinical use of polygenic risk scores: current status, barriers and future directions
Clinical use of polygenic risk scores: current status, barriers and future directions
Nature Reviews Genetics, Published online: 10 October 2025; doi:10.1038/s41576-025-00900-8This article reviews the current state of implementation of polygenic risk scores in the clinical setting, highlights key challenges and outlines future directions for the use of such scores to improve disease risk prediction and to enable personalized prevention.
www.nature.com
October 17, 2025 at 11:59 AM
ICYMI: New online! Clinical use of polygenic risk scores: current status, barriers and future directions
Reposted by Sayem Borhan, PhD
A new editorial in @ai.nejm.org explores how AI computational tools can transform causal analyses.
Researchers examine how AI can support #targettrial emulation, enhance observational data extraction and analysis, and improve efficiency of clinical trials.
🔗 ai.nejm.org/doi/full/10....
Researchers examine how AI can support #targettrial emulation, enhance observational data extraction and analysis, and improve efficiency of clinical trials.
🔗 ai.nejm.org/doi/full/10....
October 6, 2025 at 2:59 PM
A new editorial in @ai.nejm.org explores how AI computational tools can transform causal analyses.
Researchers examine how AI can support #targettrial emulation, enhance observational data extraction and analysis, and improve efficiency of clinical trials.
🔗 ai.nejm.org/doi/full/10....
Researchers examine how AI can support #targettrial emulation, enhance observational data extraction and analysis, and improve efficiency of clinical trials.
🔗 ai.nejm.org/doi/full/10....
Reposted by Sayem Borhan, PhD
The authors of a new editorial write that although computational tools cannot address biases inherent in the process of generating observational data, observational emulations may still be valuable for informing trial design and improving trial efficiency. nejm.ai/4mqiyXj
#AI #MedSky #MLSky
#AI #MedSky #MLSky
October 3, 2025 at 3:30 PM
The authors of a new editorial write that although computational tools cannot address biases inherent in the process of generating observational data, observational emulations may still be valuable for informing trial design and improving trial efficiency. nejm.ai/4mqiyXj
#AI #MedSky #MLSky
#AI #MedSky #MLSky
Reposted by Sayem Borhan, PhD
China unveils SpikingBrain1.0 a brain-like AI model.
Up to 100X faster, trained on <2% of the data.
Ultra low energy, hardware independent.
Unlike GPT/LLaMA it uses localized attention, mimicking the brain’s focus on recent context.
Potential: drones, wearables, edge AI, energy-critical apps.
Up to 100X faster, trained on <2% of the data.
Ultra low energy, hardware independent.
Unlike GPT/LLaMA it uses localized attention, mimicking the brain’s focus on recent context.
Potential: drones, wearables, edge AI, energy-critical apps.
SpikingBrain Technical Report: Spiking Brain-inspired Large Models
Mainstream Transformer-based large language models face major efficiency bottlenecks: training computation scales quadratically with sequence length, and inference memory grows linearly, limiting long...
arxiv.org
September 12, 2025 at 10:51 AM
China unveils SpikingBrain1.0 a brain-like AI model.
Up to 100X faster, trained on <2% of the data.
Ultra low energy, hardware independent.
Unlike GPT/LLaMA it uses localized attention, mimicking the brain’s focus on recent context.
Potential: drones, wearables, edge AI, energy-critical apps.
Up to 100X faster, trained on <2% of the data.
Ultra low energy, hardware independent.
Unlike GPT/LLaMA it uses localized attention, mimicking the brain’s focus on recent context.
Potential: drones, wearables, edge AI, energy-critical apps.
Metrics of one of our recent preprints since July 11, 2025. Interestingly, an email from the associate editor of a journal, especially this part, “an average of 65.5 PDF downloads per month”, prompted me to check these metrics!! #MachineLearning #FragilityFracture #Aging #BoneHealth
September 9, 2025 at 1:03 AM
Metrics of one of our recent preprints since July 11, 2025. Interestingly, an email from the associate editor of a journal, especially this part, “an average of 65.5 PDF downloads per month”, prompted me to check these metrics!! #MachineLearning #FragilityFracture #Aging #BoneHealth
Reposted by Sayem Borhan, PhD
Posts about research on Bluesky receive substantially more attention than similar posts on X, formerly called Twitter
go.nature.com/45Ftiw4
go.nature.com/45Ftiw4
Research posts on Bluesky are more original — and get better engagement
Bluesky posts about science garner more likes and reposts than similar ones on X.
go.nature.com
August 29, 2025 at 8:28 AM
Posts about research on Bluesky receive substantially more attention than similar posts on X, formerly called Twitter
go.nature.com/45Ftiw4
go.nature.com/45Ftiw4
Reposted by Sayem Borhan, PhD
Perspective by J. Weberpals et al.: Opportunities for Causal Machine Learning in Precision Oncology nejm.ai/3GOpfnl
#AI #MedSky #ML
#AI #MedSky #ML
August 1, 2025 at 1:30 PM
Perspective by J. Weberpals et al.: Opportunities for Causal Machine Learning in Precision Oncology nejm.ai/3GOpfnl
#AI #MedSky #ML
#AI #MedSky #ML
Reposted by Sayem Borhan, PhD
Multi-omics with A.I. analytics demonstrates critical role of the gut microbiome and immune response and enables accurate diagnosis of ME/CFS, may also be applicable to Long Covid.
www.nature.com/articles/s41...
www.ft.com/content/9cdf...
www.nature.com/articles/s41...
www.ft.com/content/9cdf...
AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome - Nature Medicine
Analysis of a deeply phenotyped, longitudinal cohort of 249 participants elucidates the network of concurrent molecular and macroscopic patterns related to insurgence and course of ME/CFS.
www.nature.com
July 25, 2025 at 4:08 PM
Multi-omics with A.I. analytics demonstrates critical role of the gut microbiome and immune response and enables accurate diagnosis of ME/CFS, may also be applicable to Long Covid.
www.nature.com/articles/s41...
www.ft.com/content/9cdf...
www.nature.com/articles/s41...
www.ft.com/content/9cdf...
Reposted by Sayem Borhan, PhD
Cloud-Based, Automated Solution for Transforming Clinical Datasets to the OMOP CDM #OHDSISocialShowcase
Lead: Simon Thompson
Co-Author: Abigail Carter
🔗 https://ukhealthdata.org/wp-content/uploads/2024/11/thompson_cloud_pipeline_2024symposium_poster_updated.pdf
#JoinTheJourney
Lead: Simon Thompson
Co-Author: Abigail Carter
🔗 https://ukhealthdata.org/wp-content/uploads/2024/11/thompson_cloud_pipeline_2024symposium_poster_updated.pdf
#JoinTheJourney
July 18, 2025 at 1:06 PM
Cloud-Based, Automated Solution for Transforming Clinical Datasets to the OMOP CDM #OHDSISocialShowcase
Lead: Simon Thompson
Co-Author: Abigail Carter
🔗 https://ukhealthdata.org/wp-content/uploads/2024/11/thompson_cloud_pipeline_2024symposium_poster_updated.pdf
#JoinTheJourney
Lead: Simon Thompson
Co-Author: Abigail Carter
🔗 https://ukhealthdata.org/wp-content/uploads/2024/11/thompson_cloud_pipeline_2024symposium_poster_updated.pdf
#JoinTheJourney
Reposted by Sayem Borhan, PhD
EXCITED TO SHARE! Here we show synthetic clinical data may be used in place of real-world data to answer research questions, train ML models, and to amplify sample sizes
Check it out: thejns.org/focus/view/j...
@emreszg.bsky.social
Check it out: thejns.org/focus/view/j...
@emreszg.bsky.social
July 1, 2025 at 3:02 PM
EXCITED TO SHARE! Here we show synthetic clinical data may be used in place of real-world data to answer research questions, train ML models, and to amplify sample sizes
Check it out: thejns.org/focus/view/j...
@emreszg.bsky.social
Check it out: thejns.org/focus/view/j...
@emreszg.bsky.social
Reposted by Sayem Borhan, PhD
Reposted by Sayem Borhan, PhD
Federated learning (FL) shows promise in cancer research, with FL outperforming centralized ML in 15/25 studies for breast, lung, & prostate cancer. It boosts generalizability despite reproducibility challenges. #MedSky 🩺💻 #MLSky
Advancing breast, lung and prostate cancer research with federated learning. A systematic review - npj Digital Medicine
npj Digital Medicine - Advancing breast, lung and prostate cancer research with federated learning. A systematic review
www.nature.com
May 27, 2025 at 3:10 PM
Reposted by Sayem Borhan, PhD
Research and teaching pressures can exacerbate anxiety and depression, causing many young scientists to consider quitting
https://go.nature.com/4jgygnK
https://go.nature.com/4jgygnK
Harsh criticism and unreasonable expectations worsen PhD students’ mental health
Research and teaching pressures can exacerbate anxiety and depression, causing many young scientists to consider quitting, a survey finds.
go.nature.com
January 14, 2025 at 10:18 AM
Research and teaching pressures can exacerbate anxiety and depression, causing many young scientists to consider quitting
https://go.nature.com/4jgygnK
https://go.nature.com/4jgygnK
Reposted by Sayem Borhan, PhD
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
December 3, 2024 at 2:10 PM
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪