Sarvesh Chelvanambi
@sarveshchelvanambi.bsky.social
Research fellow in Harvard Medical School studying mechanisms of cardiovascular disease
Reposted by Sarvesh Chelvanambi
Curious how our Frontiers in Science lead article could change heart medicine? This explainer article makes it easy to understand! tinyurl.com/3k49dua6
October 29, 2025 at 2:57 PM
Curious how our Frontiers in Science lead article could change heart medicine? This explainer article makes it easy to understand! tinyurl.com/3k49dua6
Reposted by Sarvesh Chelvanambi
Our lead article in Frontiers in Science shows how AI, omics, and RNA therapies could make “untreatable” heart conditions treatable. Personalized medicine is coming—but global collaboration is key! tinyurl.com/3cxw36th
October 22, 2025 at 7:33 PM
Our lead article in Frontiers in Science shows how AI, omics, and RNA therapies could make “untreatable” heart conditions treatable. Personalized medicine is coming—but global collaboration is key! tinyurl.com/3cxw36th
Excited to have this opportunity to present in #VB2025 ! @navbo.bsky.social provides such a wonderful platform to engage with the vascular biology community !!! @harvardmed.bsky.social @massgeneralbrigham.bsky.social
Tune into the exciting science senior fellow @sarveshchelvanambi.bsky.social is presenting at @navbo.bsky.social #VB2025 TODAY at 11am in Grand II, followed by @maikawa.bsky.social perspectives on the current scientific landscape at the lunchtime roundtable at 12:30 in the Cape Cod Room!
October 22, 2025 at 1:47 PM
Excited to have this opportunity to present in #VB2025 ! @navbo.bsky.social provides such a wonderful platform to engage with the vascular biology community !!! @harvardmed.bsky.social @massgeneralbrigham.bsky.social
Reposted by Sarvesh Chelvanambi
Our lead article on precision cardiovascular medicine is featured by Rainer Schulz! He highlights how new experimental models, targeted therapies, and AI can bring truly personalized CVD care to patients worldwide. tinyurl.com/mtyx6x45
October 16, 2025 at 2:39 PM
Our lead article on precision cardiovascular medicine is featured by Rainer Schulz! He highlights how new experimental models, targeted therapies, and AI can bring truly personalized CVD care to patients worldwide. tinyurl.com/mtyx6x45
Reposted by Sarvesh Chelvanambi
Thrilled to see our Frontiers in Science lead article editorialized by Hugo Ten Cate! He emphasizes harnessing patient heterogeneity, AI, and cutting-edge antithrombotics to transform cardiovascular care. Precision medicine in action! tinyurl.com/t7dxh8na
October 10, 2025 at 3:51 PM
Thrilled to see our Frontiers in Science lead article editorialized by Hugo Ten Cate! He emphasizes harnessing patient heterogeneity, AI, and cutting-edge antithrombotics to transform cardiovascular care. Precision medicine in action! tinyurl.com/t7dxh8na
Reposted by Sarvesh Chelvanambi
Reposted by Sarvesh Chelvanambi
Honored that our Frontiers in Science lead article on precision cardiovascular medicine is editorialized by global leaders Valentin Fuster, Filip Swirski, and Girish Nadkarni, emphasizing how precision & population health approaches can unite against CVD. tinyurl.com/3pn6vzur
October 8, 2025 at 3:08 PM
Honored that our Frontiers in Science lead article on precision cardiovascular medicine is editorialized by global leaders Valentin Fuster, Filip Swirski, and Girish Nadkarni, emphasizing how precision & population health approaches can unite against CVD. tinyurl.com/3pn6vzur
Reposted by Sarvesh Chelvanambi
Our Frontiers in Science lead article on precision cardiovascular medicine is editorialized by Joseph C. Wu, highlighting how reframing disease heterogeneity—from obstacle to opportunity—can transform the future of cardiovascular care. tinyurl.com/yhh3ywz2
October 9, 2025 at 1:13 PM
Our Frontiers in Science lead article on precision cardiovascular medicine is editorialized by Joseph C. Wu, highlighting how reframing disease heterogeneity—from obstacle to opportunity—can transform the future of cardiovascular care. tinyurl.com/yhh3ywz2
Such a great opportunity to contribute to this fantastic article working closely with many leaders in the field of precision medicine and disease heterogeneity in cardiovascular disease.
Big news! Our article “Precision Cardiovascular Medicine: Shifting the Innovation Paradigm” is a lead feature in Frontiers in Science, the flagship Frontiers journal—showcasing how systems biology and AI are tackling disease heterogeneity and redefining cardiovascular care. tinyurl.com/4pb2tp5h
October 7, 2025 at 9:44 PM
Such a great opportunity to contribute to this fantastic article working closely with many leaders in the field of precision medicine and disease heterogeneity in cardiovascular disease.
It was great opportunity to participate in the 2025 international long COVID pathogenesis workshop hosted by Yale University. There was highly engaged discourse in forward looking topics followed by a public session to communicate our ideas!
@virusesimmunity.bsky.social @jtmatamalas.bsky.social
@virusesimmunity.bsky.social @jtmatamalas.bsky.social
May 16, 2025 at 1:01 PM
It was great opportunity to participate in the 2025 international long COVID pathogenesis workshop hosted by Yale University. There was highly engaged discourse in forward looking topics followed by a public session to communicate our ideas!
@virusesimmunity.bsky.social @jtmatamalas.bsky.social
@virusesimmunity.bsky.social @jtmatamalas.bsky.social
Reposted by Sarvesh Chelvanambi
This morning our co-Director and global leader in the field of cardiovascular calcification, Dr. Elena Aikawa, enlightened #USHUPO2025 attendees at the new Biofluids, Secretomes, and Extracellular Vesicles session created by @toleafgirl.bsky.social .
February 25, 2025 at 2:50 PM
This morning our co-Director and global leader in the field of cardiovascular calcification, Dr. Elena Aikawa, enlightened #USHUPO2025 attendees at the new Biofluids, Secretomes, and Extracellular Vesicles session created by @toleafgirl.bsky.social .
Reposted by Sarvesh Chelvanambi
Dr. Taku Kasai of @toleafgirl.bsky.social ‘s Proteomics group shares new in-source CID HCD fragmentation technologies for ADPr in human primary macrophages with fellow proteomics enthusiasts at @us-hupo.bsky.social #USHUPO2025
February 25, 2025 at 12:25 AM
Dr. Taku Kasai of @toleafgirl.bsky.social ‘s Proteomics group shares new in-source CID HCD fragmentation technologies for ADPr in human primary macrophages with fellow proteomics enthusiasts at @us-hupo.bsky.social #USHUPO2025
Reposted by Sarvesh Chelvanambi
Thank you @us-hupo.bsky.social for a great day of amazing science! But wait — there’s more: CICS has three exciting sessions tomorrow! Mark your calendars and see you there! #USHUPO2025
February 25, 2025 at 12:21 AM
Thank you @us-hupo.bsky.social for a great day of amazing science! But wait — there’s more: CICS has three exciting sessions tomorrow! Mark your calendars and see you there! #USHUPO2025
Such an honor to be recognized by my peers!!!
@sarveshchelvanambi.bsky.social work earns him CICS’s annual Innovation Award second place! Thank you for your innovative contributions during 2024.
December 23, 2024 at 1:51 PM
Such an honor to be recognized by my peers!!!
Exciting seminar in the vascular biology seminar series by Craig Goergen from Purdue University about the use of high resolution imaging to understand etiologies of vascular disease!!!
December 19, 2024 at 11:54 PM
Exciting seminar in the vascular biology seminar series by Craig Goergen from Purdue University about the use of high resolution imaging to understand etiologies of vascular disease!!!
Reposted by Sarvesh Chelvanambi
Immunologists, time to embrace your inner neuroscientist 🧠🧪
Macrophages (yes, #macrophages) release glutamate (yes, #glutamate) to sensory neurons engaging in the muscle stretch reflex. Very cool paper! #neuroscience #immunology
www.nature.com/articles/s41...
Macrophages (yes, #macrophages) release glutamate (yes, #glutamate) to sensory neurons engaging in the muscle stretch reflex. Very cool paper! #neuroscience #immunology
www.nature.com/articles/s41...
Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature
A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...
www.nature.com
December 11, 2024 at 12:00 PM
Immunologists, time to embrace your inner neuroscientist 🧠🧪
Macrophages (yes, #macrophages) release glutamate (yes, #glutamate) to sensory neurons engaging in the muscle stretch reflex. Very cool paper! #neuroscience #immunology
www.nature.com/articles/s41...
Macrophages (yes, #macrophages) release glutamate (yes, #glutamate) to sensory neurons engaging in the muscle stretch reflex. Very cool paper! #neuroscience #immunology
www.nature.com/articles/s41...
Reposted by Sarvesh Chelvanambi
On this day in 1981, a landmark paper in NEJM described four patients with evidence of immunodeficiency associated with PJP pneumonia, disseminated CMV, and Kaposi sarcoma. The disease would come to be known as HIV/AIDS. Revisit the paper: nej.md/41iekKD
#MedSky #IDSky
#MedSky #IDSky
December 10, 2024 at 2:28 PM
On this day in 1981, a landmark paper in NEJM described four patients with evidence of immunodeficiency associated with PJP pneumonia, disseminated CMV, and Kaposi sarcoma. The disease would come to be known as HIV/AIDS. Revisit the paper: nej.md/41iekKD
#MedSky #IDSky
#MedSky #IDSky
Reposted by Sarvesh Chelvanambi
📅 Mark your calendar fo#BCVS2525, the global meeting dedicated to bridging cardiovascular discovery and practice.
Network with top researchers and dive into the latest discoveries for the treatment and management of CVD.
Don’t miss this career-essential event!
Network with top researchers and dive into the latest discoveries for the treatment and management of CVD.
Don’t miss this career-essential event!
December 9, 2024 at 5:28 PM
📅 Mark your calendar fo#BCVS2525, the global meeting dedicated to bridging cardiovascular discovery and practice.
Network with top researchers and dive into the latest discoveries for the treatment and management of CVD.
Don’t miss this career-essential event!
Network with top researchers and dive into the latest discoveries for the treatment and management of CVD.
Don’t miss this career-essential event!
Reposted by Sarvesh Chelvanambi
I'm excited to publish our State of the Art Review on #multiomics & #pharmacotherapy in #aorticstenosis #AS with Magnus Bäck, Thomas Lüscher, & Elena Aikawa in the European Heart Journal!
academic.oup.com/eurheartj/ad...
academic.oup.com/eurheartj/ad...
Calcific aortic stenosis: omics-based target discovery and therapy development
Abstract. Calcific aortic valve disease (CAVD) resulting in aortic stenosis (AS) is the most common form of valvular heart disease, affecting 2% of those o
academic.oup.com
December 4, 2024 at 9:23 PM
I'm excited to publish our State of the Art Review on #multiomics & #pharmacotherapy in #aorticstenosis #AS with Magnus Bäck, Thomas Lüscher, & Elena Aikawa in the European Heart Journal!
academic.oup.com/eurheartj/ad...
academic.oup.com/eurheartj/ad...
Reposted by Sarvesh Chelvanambi
Saw Wicked last night. Child Elphaba and adult Elphaba wear the same eyeglass frames, despite head growth over time. Did the frames magically grow with her or did she find a manufacturer that sells identical frames in child and adult sizes? Many people are asking this.
December 2, 2024 at 3:42 PM
Saw Wicked last night. Child Elphaba and adult Elphaba wear the same eyeglass frames, despite head growth over time. Did the frames magically grow with her or did she find a manufacturer that sells identical frames in child and adult sizes? Many people are asking this.
Reposted by Sarvesh Chelvanambi
“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.”
www.researchamerica.org/2023-oped-us...
www.researchamerica.org/2023-oped-us...
Research supported by NIH has led more than 100 Nobel Prizes and has supported more than 99% of drugs approved by federal regulators from 2010 to 2019.
But come January, NIH may face a wrecking ball
nytimes.com/2024/12/01/h...
But come January, NIH may face a wrecking ball
nytimes.com/2024/12/01/h...
Long a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target
nytimes.com
December 1, 2024 at 11:58 PM
“NIH produces an astounding return on investment to the American taxpayer. In Fiscal Year 2022, NIH research funding supported 568,585 jobs and generated $96.84 billion in economic activity — that’s $2.64 of economic activity for every $1 of research funding.”
www.researchamerica.org/2023-oped-us...
www.researchamerica.org/2023-oped-us...
Reposted by Sarvesh Chelvanambi
The NIH is one of the glittering jewels of health research (I have many friends & colleagues who work there or who are grantees)
This piece does a terrific job of exploring all the ways that RFK Jr & his colleague Jay Bhattacharya could destroy it (gift link) 😢
1/2
www.nytimes.com/2024/12/01/h...
This piece does a terrific job of exploring all the ways that RFK Jr & his colleague Jay Bhattacharya could destroy it (gift link) 😢
1/2
www.nytimes.com/2024/12/01/h...
Long a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target (Gift Article)
The agency long benefited from broad bipartisan support. But Republican criticism has intensified, and new choices for top health posts hope to upend the organization.
www.nytimes.com
December 1, 2024 at 9:38 PM
The NIH is one of the glittering jewels of health research (I have many friends & colleagues who work there or who are grantees)
This piece does a terrific job of exploring all the ways that RFK Jr & his colleague Jay Bhattacharya could destroy it (gift link) 😢
1/2
www.nytimes.com/2024/12/01/h...
This piece does a terrific job of exploring all the ways that RFK Jr & his colleague Jay Bhattacharya could destroy it (gift link) 😢
1/2
www.nytimes.com/2024/12/01/h...
Reposted by Sarvesh Chelvanambi
How to recover biological signal removed from batch effect correction? See www.nature.com/articles/s41...
Recovery of biological signals lost in single-cell batch integration with CellANOVA - Nature Biotechnology
A statistical framework quantifies single-cell batch variation and recovers meaningful biological signals.
www.nature.com
November 30, 2024 at 7:11 PM
How to recover biological signal removed from batch effect correction? See www.nature.com/articles/s41...
Reposted by Sarvesh Chelvanambi
Viewpoint: To safely integrate #AI into healthcare, healthcare organizations (HCOs) and clinicians must proactively mitigate risks through pre-implementation quality checks, ongoing monitoring, and patient/clinician engagement.
https://ja.ma/419xF0h
https://ja.ma/419xF0h
November 30, 2024 at 8:00 PM
Viewpoint: To safely integrate #AI into healthcare, healthcare organizations (HCOs) and clinicians must proactively mitigate risks through pre-implementation quality checks, ongoing monitoring, and patient/clinician engagement.
https://ja.ma/419xF0h
https://ja.ma/419xF0h
Reposted by Sarvesh Chelvanambi
2024 Albert Lasker Basic Medical Research Award winner Zhijian Chen describes his discovery of cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS), a DNA-sensing enzyme that triggers inflammation.
https://ja.ma/4ibukUD
https://ja.ma/4ibukUD
November 30, 2024 at 1:00 PM
2024 Albert Lasker Basic Medical Research Award winner Zhijian Chen describes his discovery of cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS), a DNA-sensing enzyme that triggers inflammation.
https://ja.ma/4ibukUD
https://ja.ma/4ibukUD