Simone Azeglio
@s-azeglio.bsky.social
From Physics to Vision Neuroscience & AI | PhD Candidate @InstVisionParis & @ENS_ULM | Enjoyed my time @FlatironCCN, @CERN | co-organizer @neurreps
Reposted by Simone Azeglio
Happy to share my first work with a connection to myopia, a collaboration with EssilorLuxottica
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Nonlinear spatial integration allows the retina to detect the sign of defocus in natural scenes
The retina can easily detect whether the eye is too small or too big thanks to the imperfections of the eye optics.
www.science.org
October 25, 2025 at 9:07 PM
Happy to share my first work with a connection to myopia, a collaboration with EssilorLuxottica
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Simone Azeglio
🕳️🐇Into the Rabbit Hull – Part II
Continuing our interpretation of DINOv2, the second part of our study concerns the *geometry of concepts* and the synthesis of our findings toward a new representational *phenomenology*:
the Minkowski Representation Hypothesis
Continuing our interpretation of DINOv2, the second part of our study concerns the *geometry of concepts* and the synthesis of our findings toward a new representational *phenomenology*:
the Minkowski Representation Hypothesis
October 15, 2025 at 5:17 PM
🕳️🐇Into the Rabbit Hull – Part II
Continuing our interpretation of DINOv2, the second part of our study concerns the *geometry of concepts* and the synthesis of our findings toward a new representational *phenomenology*:
the Minkowski Representation Hypothesis
Continuing our interpretation of DINOv2, the second part of our study concerns the *geometry of concepts* and the synthesis of our findings toward a new representational *phenomenology*:
the Minkowski Representation Hypothesis
Reposted by Simone Azeglio
Figuring out how the brain uses information from visual neurons may require new tools, writes @neurograce.bsky.social. Hear from 10 experts in the field.
#neuroskyence
www.thetransmitter.org/the-big-pict...
#neuroskyence
www.thetransmitter.org/the-big-pict...
Connecting neural activity, perception in the visual system
Figuring out how the brain uses information from visual neurons may require new tools. I asked nine experts to weigh in.
www.thetransmitter.org
October 13, 2025 at 1:23 PM
Figuring out how the brain uses information from visual neurons may require new tools, writes @neurograce.bsky.social. Hear from 10 experts in the field.
#neuroskyence
www.thetransmitter.org/the-big-pict...
#neuroskyence
www.thetransmitter.org/the-big-pict...
Reposted by Simone Azeglio
🚨 New preprint out from our lab!
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
The Rod Bipolar Cell Pathway Contributes To Surround Responses In OFF Retinal Ganglion Cells
Sensory neurons can be influenced by stimuli beyond their receptive field center, yet the mechanisms underlying this surround modulation remain poorly understood. In the retina, many OFF ganglion cell...
www.biorxiv.org
October 7, 2025 at 12:19 PM
🚨 New preprint out from our lab!
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
Reposted by Simone Azeglio
Images (or image patches) are secretly multi-channel signals over groups. Below, the dihedral group of order 8: reflecting/rotating the image permutes the values in the magenta vector. So we can reshape the image into 8-tuples that all permute according to the dihedral group (edge case diagonals).
October 3, 2025 at 9:13 AM
Images (or image patches) are secretly multi-channel signals over groups. Below, the dihedral group of order 8: reflecting/rotating the image permutes the values in the magenta vector. So we can reshape the image into 8-tuples that all permute according to the dihedral group (edge case diagonals).
Reposted by Simone Azeglio
Thrilled to see this work accepted at NeurIPS!
Kudos to @hafezghm.bsky.social for the heroic effort in demonstrating the efficacy of seq-JEPA in representation learning from multiple angles.
#MLSky 🧠🤖
Kudos to @hafezghm.bsky.social for the heroic effort in demonstrating the efficacy of seq-JEPA in representation learning from multiple angles.
#MLSky 🧠🤖
Excited to share that seq-JEPA has been accepted to NeurIPS 2025!
Preprint Alert 🚀
Can we simultaneously learn transformation-invariant and transformation-equivariant representations with self-supervised learning?
TL;DR Yes! This is possible via simple predictive learning & architectural inductive biases – without extra loss terms and predictors!
🧵 (1/10)
Can we simultaneously learn transformation-invariant and transformation-equivariant representations with self-supervised learning?
TL;DR Yes! This is possible via simple predictive learning & architectural inductive biases – without extra loss terms and predictors!
🧵 (1/10)
September 19, 2025 at 6:46 PM
Thrilled to see this work accepted at NeurIPS!
Kudos to @hafezghm.bsky.social for the heroic effort in demonstrating the efficacy of seq-JEPA in representation learning from multiple angles.
#MLSky 🧠🤖
Kudos to @hafezghm.bsky.social for the heroic effort in demonstrating the efficacy of seq-JEPA in representation learning from multiple angles.
#MLSky 🧠🤖
Reposted by Simone Azeglio
We present our preprint on ViV1T, a transformer for dynamic mouse V1 response prediction. We reveal novel response properties and confirm them in vivo.
With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social.
Paper and code at the end of the thread!
🧵1/7
With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social.
Paper and code at the end of the thread!
🧵1/7
September 19, 2025 at 12:37 PM
We present our preprint on ViV1T, a transformer for dynamic mouse V1 response prediction. We reveal novel response properties and confirm them in vivo.
With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social.
Paper and code at the end of the thread!
🧵1/7
With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social.
Paper and code at the end of the thread!
🧵1/7
Reposted by Simone Azeglio
Our illustrated guide to non-Euclidian ML is finally published!
Check it out for
⭐️ gorgeous figures (with new additions!) on topology, algebra, and geometry in the field
⭐️ broken down tables for easy reading
⭐️ accessible text, additional refs, and more
iopscience.iop.org/article/10.1...
Check it out for
⭐️ gorgeous figures (with new additions!) on topology, algebra, and geometry in the field
⭐️ broken down tables for easy reading
⭐️ accessible text, additional refs, and more
iopscience.iop.org/article/10.1...
August 1, 2025 at 3:24 PM
Our illustrated guide to non-Euclidian ML is finally published!
Check it out for
⭐️ gorgeous figures (with new additions!) on topology, algebra, and geometry in the field
⭐️ broken down tables for easy reading
⭐️ accessible text, additional refs, and more
iopscience.iop.org/article/10.1...
Check it out for
⭐️ gorgeous figures (with new additions!) on topology, algebra, and geometry in the field
⭐️ broken down tables for easy reading
⭐️ accessible text, additional refs, and more
iopscience.iop.org/article/10.1...
Reposted by Simone Azeglio
🚨New paper🚨
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
August 1, 2025 at 9:57 AM
🚨New paper🚨
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Neural manifolds went from a niche-y word to an ubiquitous term in systems neuro thanks to many interesting findings across fields. But like with any emerging term, people use it very differently.
Here, we clarify our take on the term, and review key findings & challenges rdcu.be/ex8hW
Reposted by Simone Azeglio
Do you study neural systems with feedback at different temporal-, spatial-, hierarchical-, data-, or computational- scales? Have you submitted your abstract to the "Neurocybernetics at Scale" symposium?
Due to multiple requests, new abstract submission deadline is 18 July! #AI4Science #cybernetics
Due to multiple requests, new abstract submission deadline is 18 July! #AI4Science #cybernetics
July 11, 2025 at 6:49 PM
Do you study neural systems with feedback at different temporal-, spatial-, hierarchical-, data-, or computational- scales? Have you submitted your abstract to the "Neurocybernetics at Scale" symposium?
Due to multiple requests, new abstract submission deadline is 18 July! #AI4Science #cybernetics
Due to multiple requests, new abstract submission deadline is 18 July! #AI4Science #cybernetics
NeurReps is back for its 4th edition at NeurIPS 2025! Stay tuned for updates!
📢 Call for Papers: NeurReps 2025 ‼️‼️‼️
🧠 Submit your research on symmetry, geometry, and topology in artificial and biological neural networks.
Two tracks: Proceedings (9 pages) and Extended Abstract (4 pages).
Deadline: Aug 22, 2025.
www.neurreps.org/call-for-pap...
🧠 Submit your research on symmetry, geometry, and topology in artificial and biological neural networks.
Two tracks: Proceedings (9 pages) and Extended Abstract (4 pages).
Deadline: Aug 22, 2025.
www.neurreps.org/call-for-pap...
NeurReps Workshop - Call for Papers
Call for Papers
www.neurreps.org
July 10, 2025 at 1:16 PM
NeurReps is back for its 4th edition at NeurIPS 2025! Stay tuned for updates!
Reposted by Simone Azeglio
Exciting new preprint from the lab: “Adopting a human developmental visual diet yields robust, shape-based AI vision”. A most wonderful case where brain inspiration massively improved AI solutions.
Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy
arxiv.org/abs/2507.03168
Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy
arxiv.org/abs/2507.03168
arxiv.org
July 8, 2025 at 1:04 PM
Exciting new preprint from the lab: “Adopting a human developmental visual diet yields robust, shape-based AI vision”. A most wonderful case where brain inspiration massively improved AI solutions.
Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy
arxiv.org/abs/2507.03168
Work with @zejinlu.bsky.social @sushrutthorat.bsky.social and Radek Cichy
arxiv.org/abs/2507.03168
Reposted by Simone Azeglio
Lack of spontaneous activity (#retinalwaves) in early development prevents the formation of retinal circuits critical for stabilizing images as we move through the world. doi.org/10.1016/j.ce....
June 30, 2025 at 4:21 PM
Lack of spontaneous activity (#retinalwaves) in early development prevents the formation of retinal circuits critical for stabilizing images as we move through the world. doi.org/10.1016/j.ce....
Reposted by Simone Azeglio
Reposted by Simone Azeglio
🧠✨ Join us for LAMINR: Learning and Aligning Manifolds of Single-Neuron Invariances — uncover the geometry of thought through implicit neural representations!
📅 Mon, Jun 16 @ 18:00 CET
🔗 Zoom | PW: 314159
🎙️ Part of the #NeurReps Global Seminar Series
#AI #Neuroscience #RepresentationLearning
📅 Mon, Jun 16 @ 18:00 CET
🔗 Zoom | PW: 314159
🎙️ Part of the #NeurReps Global Seminar Series
#AI #Neuroscience #RepresentationLearning
June 13, 2025 at 7:48 AM
🧠✨ Join us for LAMINR: Learning and Aligning Manifolds of Single-Neuron Invariances — uncover the geometry of thought through implicit neural representations!
📅 Mon, Jun 16 @ 18:00 CET
🔗 Zoom | PW: 314159
🎙️ Part of the #NeurReps Global Seminar Series
#AI #Neuroscience #RepresentationLearning
📅 Mon, Jun 16 @ 18:00 CET
🔗 Zoom | PW: 314159
🎙️ Part of the #NeurReps Global Seminar Series
#AI #Neuroscience #RepresentationLearning
NeurReps 2025 is starting to take shape! If you're interested in serving in the Program Committee 👇
NeurReps 2025 is on its way ! If you're interested in serving in the Program Committee, consider filling this form !
forms.gle/wgUXHT7Mq71n...
forms.gle/wgUXHT7Mq71n...
May 26, 2025 at 11:21 AM
NeurReps 2025 is starting to take shape! If you're interested in serving in the Program Committee 👇
Reposted by Simone Azeglio
Excited to share our latest study! 🧠✨ We reveal how non-direction-selective retinal ganglion cells encode motion beyond their receptive field, relaying the unconventional signals to the brain. A new insight into multimodal neurons in visual processing!
doi.org/10.1073/pnas...
doi.org/10.1073/pnas...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
doi.org
January 6, 2025 at 9:01 PM
Excited to share our latest study! 🧠✨ We reveal how non-direction-selective retinal ganglion cells encode motion beyond their receptive field, relaying the unconventional signals to the brain. A new insight into multimodal neurons in visual processing!
doi.org/10.1073/pnas...
doi.org/10.1073/pnas...
Reposted by Simone Azeglio
Why do diverse ANNs resemble brain representations? Check out our new paper with Colton Casto, @nogazs.bsky.social , Colin Conwell, Mark Richardson, & @evfedorenko.bsky.social on “Universality of representation in biological and artificial neural networks.” 🧠🤖
tinyurl.com/yckndmjt
tinyurl.com/yckndmjt
Universality of representation in biological and artificial neural networks
Many artificial neural networks (ANNs) trained with ecologically plausible objectives on naturalistic data align with behavior and neural representations in biological systems. Here, we show that this...
tinyurl.com
December 27, 2024 at 8:14 PM
Why do diverse ANNs resemble brain representations? Check out our new paper with Colton Casto, @nogazs.bsky.social , Colin Conwell, Mark Richardson, & @evfedorenko.bsky.social on “Universality of representation in biological and artificial neural networks.” 🧠🤖
tinyurl.com/yckndmjt
tinyurl.com/yckndmjt
Reposted by Simone Azeglio
Looking for the best systems #neuroscience #phd program? Champalimaud Centre for the Unknown has one! #PhDposition = fully funded. US-style lab rotations and an awesome community in Lisbon, Portugal. Apply by the end of Jan, 2025.
http://bit.ly/4iB9SwP
http://bit.ly/4iB9SwP
Education Research | Champalimaud Foundation
CR has developed and implemented several educational programmes, advanced courses and workshops, namely the PhD Programmes, INDP and ICDP.
bit.ly
December 28, 2024 at 1:41 AM
Looking for the best systems #neuroscience #phd program? Champalimaud Centre for the Unknown has one! #PhDposition = fully funded. US-style lab rotations and an awesome community in Lisbon, Portugal. Apply by the end of Jan, 2025.
http://bit.ly/4iB9SwP
http://bit.ly/4iB9SwP
Reposted by Simone Azeglio
I dream of a future in which single neuron dynamics ➡️ circuit motifs ➡️ distributed computations are taught as part of the same curriculum and no one bats an eye and everyone is happy.
Apropos of never ending discussions about whether ANNs are "good" models of the nervous system, here is a slide I present to masters students showing a network that is found in motor control circuits *across phyla* (that's pretty ubiquitous!) I ask them to guess what it does...
December 17, 2024 at 3:58 PM
I dream of a future in which single neuron dynamics ➡️ circuit motifs ➡️ distributed computations are taught as part of the same curriculum and no one bats an eye and everyone is happy.
Reposted by Simone Azeglio
New results! Visual adaptation changes the geometry of V1 population activity: frequent stimuli elicit smaller responses but become more discriminable. Similar results are seen in ANNs trained with metabolic constraints, suggesting these changes emerge from efficient coding. bit.ly/3VJHXRn
Adaptation shapes the representational geometry in mouse V1 to efficiently encode the environment
Sensory adaptation dynamically changes neural responses as a function of previous stimuli, profoundly impacting perception. The response changes induced by adaptation have been characterized in detail...
bit.ly
December 16, 2024 at 8:38 PM
New results! Visual adaptation changes the geometry of V1 population activity: frequent stimuli elicit smaller responses but become more discriminable. Similar results are seen in ANNs trained with metabolic constraints, suggesting these changes emerge from efficient coding. bit.ly/3VJHXRn
Reposted by Simone Azeglio
Created a starter pack of neuroscience in/from Paris.
Let me know if you want to be added (the 'from' can include those not in Paris anymore) or just tap in if you want to know what we're talking about!
Regardless, please re-tweet!
go.bsky.app/3Zs9w5w
Let me know if you want to be added (the 'from' can include those not in Paris anymore) or just tap in if you want to know what we're talking about!
Regardless, please re-tweet!
go.bsky.app/3Zs9w5w
December 16, 2024 at 8:45 PM
Created a starter pack of neuroscience in/from Paris.
Let me know if you want to be added (the 'from' can include those not in Paris anymore) or just tap in if you want to know what we're talking about!
Regardless, please re-tweet!
go.bsky.app/3Zs9w5w
Let me know if you want to be added (the 'from' can include those not in Paris anymore) or just tap in if you want to know what we're talking about!
Regardless, please re-tweet!
go.bsky.app/3Zs9w5w
Reposted by Simone Azeglio
Rayhan and I are presenting today our work on "Diffusion-State Guided Projected Gradient for Inverse Problems." at the D3S3 Workshop. Joint work with Dr. Anima Anandkumar #AInScience #NeurIPS2024 [1/6]
Paper: arxiv.org/abs/2410.03463
Paper: arxiv.org/abs/2410.03463
December 15, 2024 at 5:00 PM
Rayhan and I are presenting today our work on "Diffusion-State Guided Projected Gradient for Inverse Problems." at the D3S3 Workshop. Joint work with Dr. Anima Anandkumar #AInScience #NeurIPS2024 [1/6]
Paper: arxiv.org/abs/2410.03463
Paper: arxiv.org/abs/2410.03463
Reposted by Simone Azeglio
Eero Simoncelli on the geometry of the distribution of natural images
December 14, 2024 at 5:20 PM
Eero Simoncelli on the geometry of the distribution of natural images
Reposted by Simone Azeglio
NeurReps has begun! Join us today for a program combining geometry/topology, deep learning, neuroscience, and interpretability
December 14, 2024 at 5:18 PM
NeurReps has begun! Join us today for a program combining geometry/topology, deep learning, neuroscience, and interpretability