Rowan Green
@rowancallumg.bsky.social
Postdoc studying viral evolution with @asherleeks.bsky.social | previously @mermanchester.bsky.social | mutagenesis | bacteria | viruses | big R nerd 🧬🦠💻
🏳️⚧️ He/Him
🏳️⚧️ He/Him
Reposted by Rowan Green
@rowancallumg.bsky.social and @liyamiksovsky.bsky.social demonstrating our newest lab tradition - creating virus snowflakes (designed by @socialinfluenza.bsky.social ) out of submitted grants and fellowships.
🧪 #socialviruses
🧪 #socialviruses
October 31, 2025 at 9:51 PM
@rowancallumg.bsky.social and @liyamiksovsky.bsky.social demonstrating our newest lab tradition - creating virus snowflakes (designed by @socialinfluenza.bsky.social ) out of submitted grants and fellowships.
🧪 #socialviruses
🧪 #socialviruses
Reposted by Rowan Green
@rowancallumg.bsky.social @knightjar.bsky.social @rokkrasovec.bsky.social et al. study the antimutator ΔnudJ to highlight the value of considering mutation rate and mutational spectrum to understand the evolution of mutation rate-modifying alleles.
🔗 doi.org/10.1093/molbev/msaf182
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf182
#evobio #molbio
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
Abstract. The rate of spontaneous mutation is a key factor in determining the capacity of a population to adapt to a novel environment, for example, a bact
doi.org
August 20, 2025 at 5:02 PM
@rowancallumg.bsky.social @knightjar.bsky.social @rokkrasovec.bsky.social et al. study the antimutator ΔnudJ to highlight the value of considering mutation rate and mutational spectrum to understand the evolution of mutation rate-modifying alleles.
🔗 doi.org/10.1093/molbev/msaf182
#evobio #molbio
🔗 doi.org/10.1093/molbev/msaf182
#evobio #molbio
Reposted by Rowan Green
Great thread! All good, but this does grab the attention:
"our findings with ΔnudJ suggest future anti-evolution drug strategies could suppress spontaneous resistance evolution not only through minimizing resistance mutations but also by specifically limiting access to the fittest mutations."
"our findings with ΔnudJ suggest future anti-evolution drug strategies could suppress spontaneous resistance evolution not only through minimizing resistance mutations but also by specifically limiting access to the fittest mutations."
New paper out @molbioevol.bsky.social on antimutator Ecoli, mutational spectra and the distribution of fitness effects of antibiotic resistance with @knightjar.bsky.social @rokkrasovec.bsky.social and others @mermanchester.bsky.social doi.org/pzfm
Read🧵for highlights and fun stats (1/13)
Read🧵for highlights and fun stats (1/13)
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
Abstract. The rate of spontaneous mutation is a key factor in determining the capacity of a population to adapt to a novel environment, for example, a bact
doi.org
August 18, 2025 at 4:33 PM
Great thread! All good, but this does grab the attention:
"our findings with ΔnudJ suggest future anti-evolution drug strategies could suppress spontaneous resistance evolution not only through minimizing resistance mutations but also by specifically limiting access to the fittest mutations."
"our findings with ΔnudJ suggest future anti-evolution drug strategies could suppress spontaneous resistance evolution not only through minimizing resistance mutations but also by specifically limiting access to the fittest mutations."
New paper out @molbioevol.bsky.social on antimutator Ecoli, mutational spectra and the distribution of fitness effects of antibiotic resistance with @knightjar.bsky.social @rokkrasovec.bsky.social and others @mermanchester.bsky.social doi.org/pzfm
Read🧵for highlights and fun stats (1/13)
Read🧵for highlights and fun stats (1/13)
Antimutator and Mutational Spectrum Effects Can Combine to Reduce Evolutionary Potential in Escherichia coli ΔnudJ
Abstract. The rate of spontaneous mutation is a key factor in determining the capacity of a population to adapt to a novel environment, for example, a bact
doi.org
August 18, 2025 at 3:40 PM
New paper out @molbioevol.bsky.social on antimutator Ecoli, mutational spectra and the distribution of fitness effects of antibiotic resistance with @knightjar.bsky.social @rokkrasovec.bsky.social and others @mermanchester.bsky.social doi.org/pzfm
Read🧵for highlights and fun stats (1/13)
Read🧵for highlights and fun stats (1/13)
Reposted by Rowan Green
🦠 New paper led by James Horton (feat. J Cherry & @gretelwaugh.bsky.social) reveals GnT DNA motif can boost T→A mutation rates up to 1000×, & how tweaking nearby bases can fine-tune its potency.
General across bacteria + potential in synbio.
📄 academic.oup.com/mbe/advance-ar…
🔗 James’s thread ⬇️
General across bacteria + potential in synbio.
📄 academic.oup.com/mbe/advance-ar…
🔗 James’s thread ⬇️
https://academic.oup.com/mbe/advance-ar…
August 13, 2025 at 4:37 PM
🦠 New paper led by James Horton (feat. J Cherry & @gretelwaugh.bsky.social) reveals GnT DNA motif can boost T→A mutation rates up to 1000×, & how tweaking nearby bases can fine-tune its potency.
General across bacteria + potential in synbio.
📄 academic.oup.com/mbe/advance-ar…
🔗 James’s thread ⬇️
General across bacteria + potential in synbio.
📄 academic.oup.com/mbe/advance-ar…
🔗 James’s thread ⬇️
Reposted by Rowan Green
Aerobic bacteria show higher A>G (and lower G>A) mutation rate than anaerobes. First results in bioinformatic project to estimate mutation spectra across bacterial tree under my supervision. Qs and ideas are wellcome. #SMBE2025
July 22, 2025 at 1:13 PM
Aerobic bacteria show higher A>G (and lower G>A) mutation rate than anaerobes. First results in bioinformatic project to estimate mutation spectra across bacterial tree under my supervision. Qs and ideas are wellcome. #SMBE2025
Amazing conference
We organized this one: academic.oup.com/femsle/artic... in 2024. It is coming back in 2026 with 2 hubs in the US (Michigan and SoCal). It was a great experience
MEEhubs2024: A hub-based conference on microbial ecology and evolution fostering sustainability
This paper presents a multi-hub conference on microbial ecology and evolution, analyzing participant and organizer feedback to provide a template and recom
academic.oup.com
May 27, 2025 at 2:26 AM
Amazing conference
Reposted by Rowan Green
Same genome, different shape, different outcome.
SOS-independent phenotypic differences shape survival in E. coli.
Very happy to share our preprint!
SOS-independent phenotypic differences shape survival in E. coli.
Very happy to share our preprint!
New preprint led by @brunoluviano.bsky.social & Fernando Santos.
We show that filamentation enhances bacterial survival under toxic stress — not as collateral damage, but as a regulated morphological response.
TL;DR: Filamentation isn’t a symptom, it’s a strategy!
www.biorxiv.org/content/10.1...
We show that filamentation enhances bacterial survival under toxic stress — not as collateral damage, but as a regulated morphological response.
TL;DR: Filamentation isn’t a symptom, it’s a strategy!
www.biorxiv.org/content/10.1...
May 15, 2025 at 8:39 PM
Same genome, different shape, different outcome.
SOS-independent phenotypic differences shape survival in E. coli.
Very happy to share our preprint!
SOS-independent phenotypic differences shape survival in E. coli.
Very happy to share our preprint!
Empty desk in Manchester ready for new adventures in microbial evolution elsewhere 🤯🦠 I can't express how much I will miss everyone in @mermanchester.bsky.social (leaving was made a little sweeter by my first ever 'best talk' prize at #northernBUG / #YUEG at @huddersfielduni.bsky.social last week)
March 31, 2025 at 6:26 PM
Empty desk in Manchester ready for new adventures in microbial evolution elsewhere 🤯🦠 I can't express how much I will miss everyone in @mermanchester.bsky.social (leaving was made a little sweeter by my first ever 'best talk' prize at #northernBUG / #YUEG at @huddersfielduni.bsky.social last week)
Reposted by Rowan Green
We have a 2-year postdoc position available in the Lind Lab at Umeå University, Sweden! Predicting and steering experimental evolution of antibiotic resistance in Pseudomonas aeruginosa. Reposts appreciated.
umu.varbi.com/en/?jobtoken...
umu.varbi.com/en/?jobtoken...
Postdoctor, 2 years, in predicting the evolution of antibiotic resistance
The Department of Molecular Biology seeks a postdoctoral researcher who will work with forecasting and steering experimental evolution of antibiotic resistance. The employment is full-time for two yea
umu.varbi.com
March 13, 2025 at 1:13 PM
We have a 2-year postdoc position available in the Lind Lab at Umeå University, Sweden! Predicting and steering experimental evolution of antibiotic resistance in Pseudomonas aeruginosa. Reposts appreciated.
umu.varbi.com/en/?jobtoken...
umu.varbi.com/en/?jobtoken...
Thank you so much to my examiners for a great discussion. And to my supervisors and lab mates for making the past 4 years such a positive and formative experience! @mermanchester.bsky.social is the place to be ❤️ (also thank you to e coli for mutating every day, all of your mutations are appreciated)
🎉 Congratulations to Dr Rowan Green, who defended his PhD today! @rowancallumg.bsky.social
February 19, 2025 at 3:10 PM
Thank you so much to my examiners for a great discussion. And to my supervisors and lab mates for making the past 4 years such a positive and formative experience! @mermanchester.bsky.social is the place to be ❤️ (also thank you to e coli for mutating every day, all of your mutations are appreciated)
Reposted by Rowan Green
Glad to see this out today in MEE!
The rarity of mutations and the inflation of bacterial effective population sizes
besjournals.onlinelibrary.wiley.com/doi/10.1111/...
#popgen #populationgenetics #evolution #bacteriagenomics #bacteria #microsky #statsstandrews @uniofstandrews.bsky.social
The rarity of mutations and the inflation of bacterial effective population sizes
besjournals.onlinelibrary.wiley.com/doi/10.1111/...
#popgen #populationgenetics #evolution #bacteriagenomics #bacteria #microsky #statsstandrews @uniofstandrews.bsky.social
The rarity of mutations and the inflation of bacterial effective population sizes
Mutations are fundamental for evolution, and their mathematical modelling in population genetics heavily relies on our perception of their frequency and the timescale over which they occur. A comm...
besjournals.onlinelibrary.wiley.com
January 27, 2025 at 4:30 PM
Glad to see this out today in MEE!
The rarity of mutations and the inflation of bacterial effective population sizes
besjournals.onlinelibrary.wiley.com/doi/10.1111/...
#popgen #populationgenetics #evolution #bacteriagenomics #bacteria #microsky #statsstandrews @uniofstandrews.bsky.social
The rarity of mutations and the inflation of bacterial effective population sizes
besjournals.onlinelibrary.wiley.com/doi/10.1111/...
#popgen #populationgenetics #evolution #bacteriagenomics #bacteria #microsky #statsstandrews @uniofstandrews.bsky.social
Excited to speak at #PGG58 / #PopGroup58 about mutation rates, mutation spectra, antibiotic resistance and (if I talk fast enough) how the environment affects these.
Tuesday in LT3 right after lunch. 🦠🧬
Come for the mutations, stay for the Bluey colour schemed ggplots. 📊🟦🟧
Tuesday in LT3 right after lunch. 🦠🧬
Come for the mutations, stay for the Bluey colour schemed ggplots. 📊🟦🟧
January 6, 2025 at 5:46 PM
Excited to speak at #PGG58 / #PopGroup58 about mutation rates, mutation spectra, antibiotic resistance and (if I talk fast enough) how the environment affects these.
Tuesday in LT3 right after lunch. 🦠🧬
Come for the mutations, stay for the Bluey colour schemed ggplots. 📊🟦🟧
Tuesday in LT3 right after lunch. 🦠🧬
Come for the mutations, stay for the Bluey colour schemed ggplots. 📊🟦🟧
Reposted by Rowan Green
Fully funded PhD project on single-molecule dynamics of phages & plasmids.
Join us and learn a broad range of skills, from synthetic biology and evolution to 3D microscopy.
#AMR #microscopy
Please contact me directly if you wish to discuss informally and please repost!
tinyurl.com/mrjmze7j
Join us and learn a broad range of skills, from synthetic biology and evolution to 3D microscopy.
#AMR #microscopy
Please contact me directly if you wish to discuss informally and please repost!
tinyurl.com/mrjmze7j
tinyurl.com
December 17, 2024 at 1:47 PM
Fully funded PhD project on single-molecule dynamics of phages & plasmids.
Join us and learn a broad range of skills, from synthetic biology and evolution to 3D microscopy.
#AMR #microscopy
Please contact me directly if you wish to discuss informally and please repost!
tinyurl.com/mrjmze7j
Join us and learn a broad range of skills, from synthetic biology and evolution to 3D microscopy.
#AMR #microscopy
Please contact me directly if you wish to discuss informally and please repost!
tinyurl.com/mrjmze7j
Amazing project and supervisors!!! 🔬🦠🧑🔬
🚨PhD Opportunity - please share!🚨
We’re hiring a PhD student to start Sept 2025: how do bacteria ‘tame’ phage parasites, and turn them into deadly Tailocins?
Come join me, @brockhurstlab.bsky.social, Patrick Cai &
@raveentank.bsky.social as we study ZOMBIE PHAGES!
findaphd.com/phds/project...
We’re hiring a PhD student to start Sept 2025: how do bacteria ‘tame’ phage parasites, and turn them into deadly Tailocins?
Come join me, @brockhurstlab.bsky.social, Patrick Cai &
@raveentank.bsky.social as we study ZOMBIE PHAGES!
findaphd.com/phds/project...
findaphd.com
December 18, 2024 at 2:15 PM
Amazing project and supervisors!!! 🔬🦠🧑🔬
Reposted by Rowan Green
🚨 The Whelan lab is hiring! 🚨 We're looking for a Research Assistant to join our lab at U of Manchester. We're seeking someone with experience in microbiology & microbiome to support our growing group. Note this isn't a postdoc role (though keep 👀 for those announcements soon!) #Microsky 🧪 🧬 💻
Research Assistant - Impact Of Microbe-Pathogen Interactions On The Health Of Individuals With Cystic Fibrosis:Oxford Road
www.jobs.manchester.ac.uk
September 24, 2024 at 8:04 AM
🚨 The Whelan lab is hiring! 🚨 We're looking for a Research Assistant to join our lab at U of Manchester. We're seeking someone with experience in microbiology & microbiome to support our growing group. Note this isn't a postdoc role (though keep 👀 for those announcements soon!) #Microsky 🧪 🧬 💻
Reposted by Rowan Green
1st foray into T6SS with talented @mermanchester.bsky.social fellow Will Smith: eco-evo models and experimental evolution show how and why producing multiple toxins blocks resistance evolution (even though cross-resistance can evolve under single-toxin attack) www.biorxiv.org/content/10.1...
Multiplicity of Type 6 Secretion System toxins limits the evolution of resistance
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
July 31, 2024 at 5:17 PM
1st foray into T6SS with talented @mermanchester.bsky.social fellow Will Smith: eco-evo models and experimental evolution show how and why producing multiple toxins blocks resistance evolution (even though cross-resistance can evolve under single-toxin attack) www.biorxiv.org/content/10.1...
Reposted by Rowan Green
#Evo2024 Tomorrow! Giving my talk on mutators, multidrug resistance evolution and evolutionary rescue. 516B at 9:30 Tues 30 July in the Evolutionary Rescue Symposium.
July 29, 2024 at 8:53 PM
#Evo2024 Tomorrow! Giving my talk on mutators, multidrug resistance evolution and evolutionary rescue. 516B at 9:30 Tues 30 July in the Evolutionary Rescue Symposium.
#Evol2024 come along tomorrow morning at 10:30 in 520C if you want to hear about mutation rate/spectrum plasticity and an E. coli strain with a super low mutation rate 🧬🦠💻
July 29, 2024 at 5:15 PM
#Evol2024 come along tomorrow morning at 10:30 in 520C if you want to hear about mutation rate/spectrum plasticity and an E. coli strain with a super low mutation rate 🧬🦠💻
Super excited that the final version of our paper on mutation rate plasticity and oxidative stress is out now at PLoS biology! This paper shows how mutation rates are a highly dynamic trait shaped by genotype, community composition and abiotic factors. 1/8
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli
In some bacteria, mutation rates depend on environmental factors such as population density. This study uses simulation-guided experiments to show that denser microbial populations detoxify their envi...
journals.plos.org
July 26, 2024 at 8:11 PM
Super excited that the final version of our paper on mutation rate plasticity and oxidative stress is out now at PLoS biology! This paper shows how mutation rates are a highly dynamic trait shaped by genotype, community composition and abiotic factors. 1/8
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
#SMBE2024 poster ready to go! Come and chat about mutation rate plasticity, h2o2, simulations, fluctuation assays and e.coli // e.faecalis cocultures. (Also @mermanchester.bsky.social visits teotihuacan, feeling very lucky to be in Mexico).
July 7, 2024 at 7:09 PM
#SMBE2024 poster ready to go! Come and chat about mutation rate plasticity, h2o2, simulations, fluctuation assays and e.coli // e.faecalis cocultures. (Also @mermanchester.bsky.social visits teotihuacan, feeling very lucky to be in Mexico).
Reposted by Rowan Green
We had a great time at the Community Festival this weekend! It was amazing to chat with so many people about all things microbial and see the wonderful creations on our Make Your Own Bacteria stand!
June 10, 2024 at 9:35 AM
We had a great time at the Community Festival this weekend! It was amazing to chat with so many people about all things microbial and see the wonderful creations on our Make Your Own Bacteria stand!
@mermanchester.bsky.social Absolutely smashing the Manchester 10k once again 🧪🧑🔬💪
May 26, 2024 at 4:08 PM
@mermanchester.bsky.social Absolutely smashing the Manchester 10k once again 🧪🧑🔬💪
Reposted by Rowan Green
So excited to say I have been awarded a discipline hopping grant from the University of Manchester - I'll be going back to my old love Bdellovibrio and starting some work in plant systems in the dept of science and engineering 🌱 can't wait! @mermanchester.bsky.social
April 18, 2024 at 5:35 PM
So excited to say I have been awarded a discipline hopping grant from the University of Manchester - I'll be going back to my old love Bdellovibrio and starting some work in plant systems in the dept of science and engineering 🌱 can't wait! @mermanchester.bsky.social
Reposted by Rowan Green
I’m starting a special interest group with monthly seminars + discussion focused on the role of mutation in evolution covering #evobio #popgen #histsci #philsci
Upcoming speakers: @PeterALind, @DeepaAgashe, Grey Monroe, Rose Novick, Alex Klug
To join, email@umd.edu
Please repost
Upcoming speakers: @PeterALind, @DeepaAgashe, Grey Monroe, Rose Novick, Alex Klug
To join, email
Please repost
April 16, 2024 at 3:09 PM