"A healthy mind is a healthy immune system"
How can we prevent age-related changes of the immune system to preserve brain fitness?
www.cell.com/neuron/fullt...
An insightful perspective, open-access

Adipocyte-derived ferroptotic signaling mitigates obesity
www.cell.com/cell-metabol...
@cp-cellmetabolism.bsky.social

Pyrimidine synthesis enzyme CTP synthetase 1 suppresses antiviral interferon induction by deamidating IRF3
www.cell.com/immunity/ful...
@cp-immunity.bsky.social

Both cytosolic DNA species and innate immune STING signaling are required for stressed cells to activate phagocytes
www.science.org/doi/10.1126/...
@sciimmunology.bsky.social

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies
@cellcellpress.bsky.social @zhenhuachen.bsky.social
www.cell.com/cell/fulltex...

Airway-resident memory CD4 T-cell activation accelerates antigen presentation and T-cell priming in draining lymph nodes @jci-insight.bsky.social
insight.jci.org/articles/vie...

From March '24: Investigation of variants in the pre-T cell receptor α (PTCRA) chain in humans.

https://buff.ly/3ZGq2wf

A collaboration, including Rik Schrijvers,@sarahhenrickson.bsky.social, Jean-Laurent Casanova and Vivien

#Immunology @science.org

Nutrients that stimulate muscle regeneration during muscle recovery and aging!

Sara Ancel, Joris Michaud, and colleagues show nicotinamide and pyridoxine enhance muscle regeneration in aged mice: https://www.jci.org/articles/view/163648

Here is link to Shixin's new paper: www.science.org/doi/epdf/10....

Thrilled to share that our paper www.nature.com/articles/s41... is featured in a fantastic Nature News & Views piece by thomastueting.bsky.social! 🎉 Grateful for the spotlight on our research and its impact on understanding cancer immunology. www.nature.com/articles/d41... 👀👉 rdcu.be/d3cRz

HIV-1 has, for decades, been called, well, HIV-1. But no, according to the ICTV, that will no longer do, so the new name for this virus is "Lentivirus humimdef1".

Yup, you read that right.

Somebody needs to take away whatever drugs the committee is on. All viruses renamed - it's insane.

NHC-Stabilized Diazoborane (the first isolated boron-terminal N2 species, a borylene transfer reagent) | Science Magazine @science.org #ouryearinreview @gilliardgroup.bsky.social #chemsky #maingroup #boron
www.science.org/doi/10.1126/...

Review of scTrends: A living review of commercial single-cell and spatial 'omic technologies
www.cell.com/cell-genomic...
@jopz.bsky.social @adamcribbs.bsky.social

Maternal gut microbiota influence stem cell function in offspring
www.cell.com/cell-stem-ce...

Vaccination w/ neoantigens & MICB α3 antigen enhances antitumor T & NK via ILC1-derived granzymes that gasdermin D pyroptosis in tumor cells
www.researchsquare.com/article/rs-5...

This Perspective from Nov '24 by Miranda Green and Jane Foster puts the work from @annamolofskylab.bsky.social & @arimolofskylab.bsky.social & colleagues @science.org in the bigger picture of our growing understanding of meningeal immunity.

https://buff.ly/3OLThsq

#Neuroimmunology

A fully detailed method (40+ steps) to isolate/identify RNA G-quadruplex #G4 in human cells using G4-RNA precipitation (G4RP) protocol

G4RP.v1 in @natureportfolio.bsky.social: doi.org/10.1038/s414... & nature.com/articles/s41...

& G4RP.v2 now in @cellpressnews.bsky.social: doi.org/10.1016/j.xp...