David Monchaud
@dmonchaud.bsky.social
🥖😬👨🎨 (France) - 🍯🍷🌧️ (Dijon) - 🧬🔬🧪 (CNRS)
GATTACA Lab. Chemical biology & genetics. Trying to understand why and how DNA and RNA fold into ωєιя∂ℓу ѕнαρє∂ structures..
https://sites.google.com/site/monchaudchembiolab/
GATTACA Lab. Chemical biology & genetics. Trying to understand why and how DNA and RNA fold into ωєιя∂ℓу ѕнαρє∂ structures..
https://sites.google.com/site/monchaudchembiolab/
A novel biotechnological application for G4s, used for controlling the activity of a CRISPR-Cas12a device used for diagnosing human viral infection (HPV) in a spatio-temporal manner
Now in Anal. Chem. @pubs.acs.org
With Nanjing U. & @polytechniqueparis.bsky.social
@cnrs.fr
doi.org/10.1021/acs....
Now in Anal. Chem. @pubs.acs.org
With Nanjing U. & @polytechniqueparis.bsky.social
@cnrs.fr
doi.org/10.1021/acs....
November 3, 2025 at 1:17 PM
A novel biotechnological application for G4s, used for controlling the activity of a CRISPR-Cas12a device used for diagnosing human viral infection (HPV) in a spatio-temporal manner
Now in Anal. Chem. @pubs.acs.org
With Nanjing U. & @polytechniqueparis.bsky.social
@cnrs.fr
doi.org/10.1021/acs....
Now in Anal. Chem. @pubs.acs.org
With Nanjing U. & @polytechniqueparis.bsky.social
@cnrs.fr
doi.org/10.1021/acs....
The photoMultiTASQ is a new molecular tool to investigate G-quadruplex #G4 biology, notably for identifying G4 binding proteins by Chem-CLIP (chemical cross-linking and isolation by pull-down)
In ACS Bio & Med Chem Au: doi.org/10.1021/acsb...
With @iphc-strasbourg.bsky.social (FR) & WIS Rehovot (IS)
In ACS Bio & Med Chem Au: doi.org/10.1021/acsb...
With @iphc-strasbourg.bsky.social (FR) & WIS Rehovot (IS)
November 3, 2025 at 10:13 AM
The photoMultiTASQ is a new molecular tool to investigate G-quadruplex #G4 biology, notably for identifying G4 binding proteins by Chem-CLIP (chemical cross-linking and isolation by pull-down)
In ACS Bio & Med Chem Au: doi.org/10.1021/acsb...
With @iphc-strasbourg.bsky.social (FR) & WIS Rehovot (IS)
In ACS Bio & Med Chem Au: doi.org/10.1021/acsb...
With @iphc-strasbourg.bsky.social (FR) & WIS Rehovot (IS)
Stimulating scientific days #ChemBioParis2025.
Super great to hear Shankar Balasubramanian speaking about G-quadruplex, Matthew Disney about ChemCLIP and Dan Nomura about MYC druggability, among many others
Kudos to @borisvauzeilles.bsky.social & the team for the organization chembioparis2025.com
Super great to hear Shankar Balasubramanian speaking about G-quadruplex, Matthew Disney about ChemCLIP and Dan Nomura about MYC druggability, among many others
Kudos to @borisvauzeilles.bsky.social & the team for the organization chembioparis2025.com
October 9, 2025 at 7:05 AM
Stimulating scientific days #ChemBioParis2025.
Super great to hear Shankar Balasubramanian speaking about G-quadruplex, Matthew Disney about ChemCLIP and Dan Nomura about MYC druggability, among many others
Kudos to @borisvauzeilles.bsky.social & the team for the organization chembioparis2025.com
Super great to hear Shankar Balasubramanian speaking about G-quadruplex, Matthew Disney about ChemCLIP and Dan Nomura about MYC druggability, among many others
Kudos to @borisvauzeilles.bsky.social & the team for the organization chembioparis2025.com
Reposted by David Monchaud
We’ve developed the first-ever method to control nucleic acid activity and gene-expressing synthetic cells with a deeply tissue penetrating alternating magnetic field 🧬 🧪 🧲!!!
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells - Nature Chemistry
The programmability of synthetic cells, comprising lipid vesicles that are capable of imitating the structure and function of living cells, facilitates their application as drug delivery devices. Now,...
www.nature.com
September 2, 2025 at 9:31 AM
We’ve developed the first-ever method to control nucleic acid activity and gene-expressing synthetic cells with a deeply tissue penetrating alternating magnetic field 🧬 🧪 🧲!!!
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Published in *Nature Chemistry*
Led by Ellen Parkes
@syncelleu.bsky.social #chemsky
www.nature.com/articles/s41...
Reposted by David Monchaud
What happens when a DNA-junction binding compound is lengthened? Intriguingly, the larger pi surfaces widen the range of junctions targeted! Just out in JBIC -congratulations to authors
Sam and Hannah -first paper from her MSc by research studies @uobchemistry.bsky.social
doi.org/10.1007/s007...
Sam and Hannah -first paper from her MSc by research studies @uobchemistry.bsky.social
doi.org/10.1007/s007...
September 17, 2025 at 7:54 AM
What happens when a DNA-junction binding compound is lengthened? Intriguingly, the larger pi surfaces widen the range of junctions targeted! Just out in JBIC -congratulations to authors
Sam and Hannah -first paper from her MSc by research studies @uobchemistry.bsky.social
doi.org/10.1007/s007...
Sam and Hannah -first paper from her MSc by research studies @uobchemistry.bsky.social
doi.org/10.1007/s007...
Honored to have been interviewed by Pour La Science, a wide-audience scientific magazine, to discuss the results from @simonelsasser.bsky.social / @puckknipscheer.bsky.social published in @science.org about how DNA repair proteins mold G-quadruplex #G4
👉 tinyurl.com/3k6pxu6d
(sorry, in French only)
👉 tinyurl.com/3k6pxu6d
(sorry, in French only)
August 28, 2025 at 6:47 AM
Honored to have been interviewed by Pour La Science, a wide-audience scientific magazine, to discuss the results from @simonelsasser.bsky.social / @puckknipscheer.bsky.social published in @science.org about how DNA repair proteins mold G-quadruplex #G4
👉 tinyurl.com/3k6pxu6d
(sorry, in French only)
👉 tinyurl.com/3k6pxu6d
(sorry, in French only)
Happy to describe a novel strategy to detect pollutants in food with a super high sensitivity, using G-quadruplex #G4 based biosensing devices.
A collaboration with the University of Nanjing (CN) and Polytechnique Palaiseau (FR)
Now in Anal. Chem. (@pubs.acs.org): doi.org/10.1021/acs....
A collaboration with the University of Nanjing (CN) and Polytechnique Palaiseau (FR)
Now in Anal. Chem. (@pubs.acs.org): doi.org/10.1021/acs....
August 27, 2025 at 7:13 AM
Happy to describe a novel strategy to detect pollutants in food with a super high sensitivity, using G-quadruplex #G4 based biosensing devices.
A collaboration with the University of Nanjing (CN) and Polytechnique Palaiseau (FR)
Now in Anal. Chem. (@pubs.acs.org): doi.org/10.1021/acs....
A collaboration with the University of Nanjing (CN) and Polytechnique Palaiseau (FR)
Now in Anal. Chem. (@pubs.acs.org): doi.org/10.1021/acs....
Happy to describe a novel strategy to combat colorectal cancer by pharmacologically modulating G-quadruplex #G4 RNA found in dysregulated lncRNAs, using the molecular helicase PhpC.
A collaboration with ITTGN (India) and supported by @embo.org fellowships
Now in BMC Biol.: doi.org/10.1186/s129...
A collaboration with ITTGN (India) and supported by @embo.org fellowships
Now in BMC Biol.: doi.org/10.1186/s129...
August 26, 2025 at 6:41 AM
Happy to describe a novel strategy to combat colorectal cancer by pharmacologically modulating G-quadruplex #G4 RNA found in dysregulated lncRNAs, using the molecular helicase PhpC.
A collaboration with ITTGN (India) and supported by @embo.org fellowships
Now in BMC Biol.: doi.org/10.1186/s129...
A collaboration with ITTGN (India) and supported by @embo.org fellowships
Now in BMC Biol.: doi.org/10.1186/s129...
Reposted by David Monchaud
Ready for super-G4s? We have identified clusters of G4s in intergenic regions that act as super-enhancers in ovarian cancer cells, hence the name super-G4! These are de novo super-enhancers that are not underpinned by canonical epigenetic marks, supporting the epigenetic role of G4s rdcu.be/evXtf
July 12, 2025 at 11:32 AM
Ready for super-G4s? We have identified clusters of G4s in intergenic regions that act as super-enhancers in ovarian cancer cells, hence the name super-G4! These are de novo super-enhancers that are not underpinned by canonical epigenetic marks, supporting the epigenetic role of G4s rdcu.be/evXtf
Reposted by David Monchaud
Excited our paper is out! G-quadruplex (G4) unwinding via an intricate G-loop assembly and disassembly mechanism maintains genome integrity. Pioneered by Koichi Sato with great collaborators Jing Lyu and @simonelsasser.bsky.social Check it out: www.science.org/doi/10.1126/science.adr0493 🧵(1/4)
RNA transcripts regulate G-quadruplex landscapes through G-loop formation
G-quadruplexes (G4s) are prevalent DNA structures that regulate transcription but also threaten genome stability. How G4 dynamics are controlled remains poorly understood. Here, we report that RNA tra...
www.science.org
June 13, 2025 at 9:33 AM
Excited our paper is out! G-quadruplex (G4) unwinding via an intricate G-loop assembly and disassembly mechanism maintains genome integrity. Pioneered by Koichi Sato with great collaborators Jing Lyu and @simonelsasser.bsky.social Check it out: www.science.org/doi/10.1126/science.adr0493 🧵(1/4)
A novel demonstration of the G-quadruplex #G4 unfolding properties of PhpC, a quite unique prototype of G4 unfolder (or molecular helicase) we developed in the lab
In collaboration with C. Cruz @ubeirainterior.bsky.social and R.H.E. Huson @westernu.bsky.social
👉 doi.org/10.1016/j.ij...
In collaboration with C. Cruz @ubeirainterior.bsky.social and R.H.E. Huson @westernu.bsky.social
👉 doi.org/10.1016/j.ij...
June 20, 2025 at 11:50 AM
A novel demonstration of the G-quadruplex #G4 unfolding properties of PhpC, a quite unique prototype of G4 unfolder (or molecular helicase) we developed in the lab
In collaboration with C. Cruz @ubeirainterior.bsky.social and R.H.E. Huson @westernu.bsky.social
👉 doi.org/10.1016/j.ij...
In collaboration with C. Cruz @ubeirainterior.bsky.social and R.H.E. Huson @westernu.bsky.social
👉 doi.org/10.1016/j.ij...
Reposted by David Monchaud
Call for Expressions of Interest – MSCA Postdocs 2025
Join my group at CiQUS to work on “Selective DNA Junction Binders for Targeted Anticancer Therapy”.
Deadline: June 15
www.usc.es/ciqus/en/MSC...
#MSCA #CiQUS #DNAJunctions #Postdoc #ChemSky #ChemBioSky
Join my group at CiQUS to work on “Selective DNA Junction Binders for Targeted Anticancer Therapy”.
Deadline: June 15
www.usc.es/ciqus/en/MSC...
#MSCA #CiQUS #DNAJunctions #Postdoc #ChemSky #ChemBioSky
May 26, 2025 at 12:03 PM
Call for Expressions of Interest – MSCA Postdocs 2025
Join my group at CiQUS to work on “Selective DNA Junction Binders for Targeted Anticancer Therapy”.
Deadline: June 15
www.usc.es/ciqus/en/MSC...
#MSCA #CiQUS #DNAJunctions #Postdoc #ChemSky #ChemBioSky
Join my group at CiQUS to work on “Selective DNA Junction Binders for Targeted Anticancer Therapy”.
Deadline: June 15
www.usc.es/ciqus/en/MSC...
#MSCA #CiQUS #DNAJunctions #Postdoc #ChemSky #ChemBioSky
The best of the best!
The core of our community on #DNA #RNA junctions during the first meeting #IMAJ1 including @biometalusc.bsky.social, @sebastien-britton.bsky.social, @christinecardin.bsky.social, @granzhan.bsky.social, Jean-Louis, Mark and many others
Thank you again for your participation!
The core of our community on #DNA #RNA junctions during the first meeting #IMAJ1 including @biometalusc.bsky.social, @sebastien-britton.bsky.social, @christinecardin.bsky.social, @granzhan.bsky.social, Jean-Louis, Mark and many others
Thank you again for your participation!
May 20, 2025 at 8:33 AM
The best of the best!
The core of our community on #DNA #RNA junctions during the first meeting #IMAJ1 including @biometalusc.bsky.social, @sebastien-britton.bsky.social, @christinecardin.bsky.social, @granzhan.bsky.social, Jean-Louis, Mark and many others
Thank you again for your participation!
The core of our community on #DNA #RNA junctions during the first meeting #IMAJ1 including @biometalusc.bsky.social, @sebastien-britton.bsky.social, @christinecardin.bsky.social, @granzhan.bsky.social, Jean-Louis, Mark and many others
Thank you again for your participation!
It was an absolute thrill and a real pleasure to organize the first meeting on #DNA #RNA junctions in Paris.
Fantastic talks, lively discussions—and some excellent wine too! 🍷😁
A very promising beginning for this new community
Stay tuned—we’ll be back next year!
#IMAJ1 #CNRSchimie @cnrs.fr
Fantastic talks, lively discussions—and some excellent wine too! 🍷😁
A very promising beginning for this new community
Stay tuned—we’ll be back next year!
#IMAJ1 #CNRSchimie @cnrs.fr
May 19, 2025 at 2:34 PM
It was an absolute thrill and a real pleasure to organize the first meeting on #DNA #RNA junctions in Paris.
Fantastic talks, lively discussions—and some excellent wine too! 🍷😁
A very promising beginning for this new community
Stay tuned—we’ll be back next year!
#IMAJ1 #CNRSchimie @cnrs.fr
Fantastic talks, lively discussions—and some excellent wine too! 🍷😁
A very promising beginning for this new community
Stay tuned—we’ll be back next year!
#IMAJ1 #CNRSchimie @cnrs.fr
Reposted by David Monchaud
The first IRN on Nucleic Acid Junctions meeting couldn’t have gone any better. Brilliant science, inspiring people, and a perfect atmosphere. Huge thanks to @dmonchaud.bsky.social for making it happen
#IMAJ1 #ChemSky #DNAjunctions
#IMAJ1 #ChemSky #DNAjunctions
Thank you, Miguel!
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
Great success at the first IRN on Nucleic Acid Junctions meeting — inspiring science, engaging discussions, and exciting prospects.
Thanks to all, especially @dmonchaud.bsky.social for the leadership!
@cnrs.fr @akellett.bsky.social @granzhan.bsky.social
#IMAJ1 #ChemSky #DNAjunctions
Thanks to all, especially @dmonchaud.bsky.social for the leadership!
@cnrs.fr @akellett.bsky.social @granzhan.bsky.social
#IMAJ1 #ChemSky #DNAjunctions
May 16, 2025 at 2:03 PM
The first IRN on Nucleic Acid Junctions meeting couldn’t have gone any better. Brilliant science, inspiring people, and a perfect atmosphere. Huge thanks to @dmonchaud.bsky.social for making it happen
#IMAJ1 #ChemSky #DNAjunctions
#IMAJ1 #ChemSky #DNAjunctions
Thank you, Miguel!
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
Great success at the first IRN on Nucleic Acid Junctions meeting — inspiring science, engaging discussions, and exciting prospects.
Thanks to all, especially @dmonchaud.bsky.social for the leadership!
@cnrs.fr @akellett.bsky.social @granzhan.bsky.social
#IMAJ1 #ChemSky #DNAjunctions
Thanks to all, especially @dmonchaud.bsky.social for the leadership!
@cnrs.fr @akellett.bsky.social @granzhan.bsky.social
#IMAJ1 #ChemSky #DNAjunctions
May 15, 2025 at 8:43 PM
Thank you, Miguel!
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
It was great to have you all here in Paris. It was our first meeting, but it was so exciting and promising! I'm eager to repeat this beautiful experience next year, certainly in the UK! Stay tuned!
#DNA #DNAjunction #iMAJ #IRN
Reposted by David Monchaud
A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...
April 9, 2025 at 9:31 PM
A project five years in the making, we've now published complete "T2T" genomes for six additional ape species! It turns out that finishing (and analyzing) six genomes is slightly more work than one... doi.org/10.1038/s415...
Reposted by David Monchaud
Excited to present our new @naturecomms.bsky.social paper with Stefania Millevoi's lab on the role of #RNA G-quadruplex in mitochondrial RNA. We find that
#RG4 can be exploited to inhibit mitochondrial translation and disrupt #cancer cells proliferation.
www.nature.com/articles/s41...
#RG4 can be exploited to inhibit mitochondrial translation and disrupt #cancer cells proliferation.
www.nature.com/articles/s41...
RNA G-quadruplexes control mitochondria-localized mRNA translation and energy metabolism - Nature Communications
Cancer cells rely on mitochondria for energy and macromolecule synthesis. Here, the authors show that RNA G-quadruplex dynamics, driven by oncogenic signals, regulate the translation of nuclear-encode...
www.nature.com
April 9, 2025 at 7:30 AM
Excited to present our new @naturecomms.bsky.social paper with Stefania Millevoi's lab on the role of #RNA G-quadruplex in mitochondrial RNA. We find that
#RG4 can be exploited to inhibit mitochondrial translation and disrupt #cancer cells proliferation.
www.nature.com/articles/s41...
#RG4 can be exploited to inhibit mitochondrial translation and disrupt #cancer cells proliferation.
www.nature.com/articles/s41...
We're thrilled to have contributed to this @naturecomms.bsky.social paper on the role of G-quadruplex #G4 in mitochondrial RNA
G4s can be targeted with ligands to inhibit mitochondrial translation and eventually functions, which jeopardizes cancer cells fate
This is huge!
👉 doi.org/10.1038/s414...
G4s can be targeted with ligands to inhibit mitochondrial translation and eventually functions, which jeopardizes cancer cells fate
This is huge!
👉 doi.org/10.1038/s414...
April 7, 2025 at 1:59 PM
We're thrilled to have contributed to this @naturecomms.bsky.social paper on the role of G-quadruplex #G4 in mitochondrial RNA
G4s can be targeted with ligands to inhibit mitochondrial translation and eventually functions, which jeopardizes cancer cells fate
This is huge!
👉 doi.org/10.1038/s414...
G4s can be targeted with ligands to inhibit mitochondrial translation and eventually functions, which jeopardizes cancer cells fate
This is huge!
👉 doi.org/10.1038/s414...
Reposted by David Monchaud
How do replisomes walk on DNA? And what happens when they run into a G-quadruplex? @sahilbatra.bsky.social and @benallwein.bsky.social provide unexpected insight in our latest paper with Richard Hite @mskcancercenter.bsky.social @science.org www.science.org/doi/10.1126/.... Congrats to all authors!
G-quadruplex–stalled eukaryotic replisome structure reveals helical inchworm DNA translocation
DNA G-quadruplexes (G4s) are non–B-form DNA secondary structures that threaten genome stability by impeding DNA replication. To elucidate how G4s induce replication fork arrest, we characterized fork ...
www.science.org
March 6, 2025 at 9:30 PM
How do replisomes walk on DNA? And what happens when they run into a G-quadruplex? @sahilbatra.bsky.social and @benallwein.bsky.social provide unexpected insight in our latest paper with Richard Hite @mskcancercenter.bsky.social @science.org www.science.org/doi/10.1126/.... Congrats to all authors!
Reposted by David Monchaud
Have a look at our newest commentary in @pnas.org :
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
G-quadruplexes and their unexpected ability to fold proteins | PNAS
G-quadruplexes and their unexpected ability to fold proteins
www.pnas.org
March 11, 2025 at 9:18 AM
Have a look at our newest commentary in @pnas.org :
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
"G-quadruplexes and their unexpected ability to fold proteins"
Full text: www.pnas.org/doi/10.1073/...
#G4 #quadruplex #proteins #folding
Reposted by David Monchaud
In case you missed it, you can now watch the excellent 2025 Francis Crick Lecture from Shankar Balasubramanian on our YouTube channel!
Shankar delivered an excellent talk on ‘The DNA Quadruplex Helix’ – it’s not one to miss!
youtu.be/RIDAP0Ds2yo
Shankar delivered an excellent talk on ‘The DNA Quadruplex Helix’ – it’s not one to miss!
youtu.be/RIDAP0Ds2yo
Crick Lecture 2025: The DNA Quadruplex Helix by Shankar Balasubramanian
YouTube video by MRC Laboratory of Molecular Biology
youtu.be
March 11, 2025 at 10:10 AM
In case you missed it, you can now watch the excellent 2025 Francis Crick Lecture from Shankar Balasubramanian on our YouTube channel!
Shankar delivered an excellent talk on ‘The DNA Quadruplex Helix’ – it’s not one to miss!
youtu.be/RIDAP0Ds2yo
Shankar delivered an excellent talk on ‘The DNA Quadruplex Helix’ – it’s not one to miss!
youtu.be/RIDAP0Ds2yo
Welcome to BlueSky @jamchemsoc.bsky.social !
Happy to celebrate your arrival amongst us with this new article (doi.org/10.1021/jacs...), in which we report on CoRP-seq, a technique for mapping RNA G-quadruplex #G4 transcriptome-wide in a fast, cheap and simple manner
#chembio #AcademicSky #SciSky
Happy to celebrate your arrival amongst us with this new article (doi.org/10.1021/jacs...), in which we report on CoRP-seq, a technique for mapping RNA G-quadruplex #G4 transcriptome-wide in a fast, cheap and simple manner
#chembio #AcademicSky #SciSky
March 11, 2025 at 10:36 AM
Welcome to BlueSky @jamchemsoc.bsky.social !
Happy to celebrate your arrival amongst us with this new article (doi.org/10.1021/jacs...), in which we report on CoRP-seq, a technique for mapping RNA G-quadruplex #G4 transcriptome-wide in a fast, cheap and simple manner
#chembio #AcademicSky #SciSky
Happy to celebrate your arrival amongst us with this new article (doi.org/10.1021/jacs...), in which we report on CoRP-seq, a technique for mapping RNA G-quadruplex #G4 transcriptome-wide in a fast, cheap and simple manner
#chembio #AcademicSky #SciSky
Reposted by David Monchaud
Versatile Click Chemistry-based Approaches to Illuminate DNA and RNA G-Quadruplexes in Human Cells
Work by Angélique Pipier and @dmonchaud.bsky.social at ICMUB - Institut de Chimie Moléculaire de l'Université Bourgogne Europe.
#LifeSciences #Reproducibility #MolecularBiology
Work by Angélique Pipier and @dmonchaud.bsky.social at ICMUB - Institut de Chimie Moléculaire de l'Université Bourgogne Europe.
#LifeSciences #Reproducibility #MolecularBiology
February 11, 2025 at 2:48 PM
Versatile Click Chemistry-based Approaches to Illuminate DNA and RNA G-Quadruplexes in Human Cells
Work by Angélique Pipier and @dmonchaud.bsky.social at ICMUB - Institut de Chimie Moléculaire de l'Université Bourgogne Europe.
#LifeSciences #Reproducibility #MolecularBiology
Work by Angélique Pipier and @dmonchaud.bsky.social at ICMUB - Institut de Chimie Moléculaire de l'Université Bourgogne Europe.
#LifeSciences #Reproducibility #MolecularBiology
A fully detailed protocol to visualize G-quadruplex #G4 DNA/RNA in human cells using clickable G4 ligands (in situ click imaging) now in @bio-protocol.bsky.social
Interested?? All you need is:
- the clickable ligand: www.sigmaaldrich.com/FR/en/produc...
- and the protocol: doi.org/10.21769/Bio...
Interested?? All you need is:
- the clickable ligand: www.sigmaaldrich.com/FR/en/produc...
- and the protocol: doi.org/10.21769/Bio...
January 22, 2025 at 7:56 AM
A fully detailed protocol to visualize G-quadruplex #G4 DNA/RNA in human cells using clickable G4 ligands (in situ click imaging) now in @bio-protocol.bsky.social
Interested?? All you need is:
- the clickable ligand: www.sigmaaldrich.com/FR/en/produc...
- and the protocol: doi.org/10.21769/Bio...
Interested?? All you need is:
- the clickable ligand: www.sigmaaldrich.com/FR/en/produc...
- and the protocol: doi.org/10.21769/Bio...