puckknipscheer.bsky.social
@puckknipscheer.bsky.social
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Registration is open!🧬

Join us at Egmond aan Zee (April 19–24, 2026) for the next DNA Repair Meeting. We have an amazing line-up of speakers.

📅 Deadline for early registration: Jan 10, 2026
🔗 dnarepairmeeting-egmond2026.com
November 12, 2025 at 3:04 PM
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Ready to establish your own research group at the Hubrecht Institute for Molecular and Developmental Biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply! https://f.mtr.cool/jncxfqkuds
September 26, 2025 at 1:53 PM
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The latest work from ours and @vram142.bsky.social lab is out! True teamwork to visualize nascent chromatin with strand resolution, using a fully reconstituted system. Very proud of superstar-PhD student Bruna, and @palindromephd.bsky.social. Learning so much from Vijay’s amazing technologies! RT
September 21, 2025 at 7:12 AM
Are you interested in working on related projects? 🌱
The Knipscheer lab at the Hubrecht Institute (Utrecht, the Netherlands) has openings for a postdoc and a PhD position.
Apply here: www.hubrecht.eu/jobs
September 19, 2025 at 12:32 PM
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Just one month left to apply for the Hubrecht International PhD Program! This fully funded 4-year PhD offers the opportunity to join a high-profile lab in molecular & developmental biology, exceptional training, and mentorship from leading scientists.

Apply before September 15 www.hubrecht.eu/hipp/
August 14, 2025 at 10:02 AM
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🧬 Looking for a PhD position in molecular or developmental biology? 🔬

✉️ The Hubrecht Institute now has its very own PhD program! Applications are open and will be accepted until September 15th. Read more here 👉 www.hubrecht.eu/hipp/
July 10, 2025 at 11:19 AM
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Congrats to Koichi Sato and @puckknipscheer.bsky.social on this beautiful paper! The biochemistry is 🤯 Happy to help with scEdUseq to pinpoint the DNA replication defects! 🎉🧬

RNA transcripts regulate G-quadruplex landscapes through G-loop formation | Science www.science.org/doi/10.1126/...
RNA transcripts regulate G-quadruplex landscapes through G-loop formation
G-quadruplexes (G4s) are prevalent DNA structures that regulate transcription but also threaten genome stability. How G4 dynamics are controlled remains poorly understood. Here, we report that RNA tra...
www.science.org
June 13, 2025 at 7:04 AM
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New work from the Knipscheer group published in @science.org reveals a mechanism involving RNA and DNA repair proteins that helps cells remove G-quadruplex structures. G4 structures are knot-like formations in DNA that can cause damage if left unresolved. www.hubrecht.eu/cells-untie-dna-knots/
Knot good: How cells untie DNA to protect the genome
New work from the Knipscheer group reveals a mechanism involving RNA and DNA repair proteins that helps cells safely remove G-quadruplex (G4) structures.
www.hubrecht.eu
June 13, 2025 at 8:37 AM
Excited our paper is out! G-quadruplex (G4) unwinding via an intricate G-loop assembly and disassembly mechanism maintains genome integrity. Pioneered by Koichi Sato with great collaborators Jing Lyu and @simonelsasser.bsky.social Check it out: www.science.org/doi/10.1126/science.adr0493 🧵(1/4)
RNA transcripts regulate G-quadruplex landscapes through G-loop formation
G-quadruplexes (G4s) are prevalent DNA structures that regulate transcription but also threaten genome stability. How G4 dynamics are controlled remains poorly understood. Here, we report that RNA tra...
www.science.org
June 13, 2025 at 9:33 AM
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Another day another review request (10 days). With the usual ‘suggest alternatives from underrepresented communities’. This approach doesn’t just overburden the underrepresented groups, it under-burdens the overrepresented ones, freeing them up to do stuff that is ‘objectively’ judged as ‘better’.
April 10, 2025 at 10:55 AM
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Mark your calendar: the next Egmond DNA repair meeting will take place in 2026 from April 19 - 24!

You can pre-register to receive announcement here: forms.lumc.nl/lumc2/Egmond

Registration will open by June 2025/
December 23, 2024 at 12:46 PM