Radhika Jangi
@radster95.bsky.social
Bio student in the Battle Lab at JHU
Interested in dynamic effects of genetic variation across differentiation
Interested in dynamic effects of genetic variation across differentiation
Reposted by Radhika Jangi
Exciting updates!!
(1) I just opened my lab at Boston Children’s Hospital (Harvard-affiliated)
(2) I’m hiring a postdoc focused on integrating GWAS and functional genomic data. Reach out if you’re interested or connect at ASHG next week!
(3) Learn more at stroberlab.com
(1) I just opened my lab at Boston Children’s Hospital (Harvard-affiliated)
(2) I’m hiring a postdoc focused on integrating GWAS and functional genomic data. Reach out if you’re interested or connect at ASHG next week!
(3) Learn more at stroberlab.com
Strober Lab
The Strober lab is a computational group at Boston Children's Hospital (a Harvard Medical School affiliated hospital) focused on developing statistical and machine learning tools applied to human gene...
stroberlab.com
October 7, 2025 at 6:55 PM
Exciting updates!!
(1) I just opened my lab at Boston Children’s Hospital (Harvard-affiliated)
(2) I’m hiring a postdoc focused on integrating GWAS and functional genomic data. Reach out if you’re interested or connect at ASHG next week!
(3) Learn more at stroberlab.com
(1) I just opened my lab at Boston Children’s Hospital (Harvard-affiliated)
(2) I’m hiring a postdoc focused on integrating GWAS and functional genomic data. Reach out if you’re interested or connect at ASHG next week!
(3) Learn more at stroberlab.com
Reposted by Radhika Jangi
(1/10) We’re excited to share our new preprint (doi.org/10.1101/2025...), which uncovers the spatiomolecular landscape of the human nucleus accumbens (NAc), by integrating snRNA-seq with Visium spatial transcriptomics across 10 control donors. 🧠 #NAcLIBD #snRNAseq #10xVisium
September 15, 2025 at 5:06 PM
(1/10) We’re excited to share our new preprint (doi.org/10.1101/2025...), which uncovers the spatiomolecular landscape of the human nucleus accumbens (NAc), by integrating snRNA-seq with Visium spatial transcriptomics across 10 control donors. 🧠 #NAcLIBD #snRNAseq #10xVisium
Reposted by Radhika Jangi
Really excited to share our new PRS method, developed with @aprilkim.bsky.social and @alexisbattle.bsky.social ! Our approach is to use a lot of recently developed functional annotations to better estimate the weights of the SNPs.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Polygenic prediction of phenotypes with a neural empirical Bayes approach
Polygenic risk scores (PRS) estimate the expected value of a phenotype based on individual genotypes. Although statistical approaches for calculating PRS have advanced considerably in recent years, fe...
www.medrxiv.org
July 22, 2025 at 9:25 PM
Really excited to share our new PRS method, developed with @aprilkim.bsky.social and @alexisbattle.bsky.social ! Our approach is to use a lot of recently developed functional annotations to better estimate the weights of the SNPs.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Delicious post!!!
BLOG ALERT! 🧬 If you do RNA-seq, ATAC-seq, ChIP-seq, or modeling thereof, you may be overlooking LD score regression methods. These should be standard tools to study genes, variants, and regions en masse, but they are hard to understand. I wrote intros:
June 26, 2025 at 2:35 PM
Delicious post!!!
Reposted by Radhika Jangi
People always stop me in the street to ask: "Yoav, where are the disease-associated eQLTs? We found a lot in GTEx but we can't find anymore. Do you know where they are?"
(For the record, no one has ever asked me this, but it is a really good question!)
I think we know where they are.
(For the record, no one has ever asked me this, but it is a really good question!)
I think we know where they are.
June 10, 2025 at 2:20 PM
People always stop me in the street to ask: "Yoav, where are the disease-associated eQLTs? We found a lot in GTEx but we can't find anymore. Do you know where they are?"
(For the record, no one has ever asked me this, but it is a really good question!)
I think we know where they are.
(For the record, no one has ever asked me this, but it is a really good question!)
I think we know where they are.
Reposted by Radhika Jangi
My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.
It’s available on Amazon: tinyurl.com/mx2hewen
It’s available on Amazon: tinyurl.com/mx2hewen
January 17, 2025 at 2:30 PM
My book, An Intuitive Primer on Effective Functional Genomics Study Design, is published! I’d really appreciate it if you could help spread the word, and I’d love to hear your thoughts and feedback. I hope people will find it useful.
It’s available on Amazon: tinyurl.com/mx2hewen
It’s available on Amazon: tinyurl.com/mx2hewen
Reposted by Radhika Jangi
Heading to Minneapolis next week to share this work at STATGEN2025!
May 17, 2025 at 9:23 PM
Heading to Minneapolis next week to share this work at STATGEN2025!
Reposted by Radhika Jangi
I'm defending my PhD next Friday, May 23!(!!!!). I'll be highlighting our work looking at aneuploidy in early human development. If you're interested I'd love to have you join via Zoom (DM me for info) or on the Homewood campus!
May 16, 2025 at 1:27 PM
I'm defending my PhD next Friday, May 23!(!!!!). I'll be highlighting our work looking at aneuploidy in early human development. If you're interested I'd love to have you join via Zoom (DM me for info) or on the Homewood campus!
Hire him!! You won’t regret it!!!
Our pre-print on investigating variation in South Asian genomes is now out!
Thank you to @mikeschatz.bsky.social, @rajivmccoy.bsky.social and @aabiddanda.bsky.social for all their work on this.
🧵 A thread on the key results and takeaways from our work:
Thank you to @mikeschatz.bsky.social, @rajivmccoy.bsky.social and @aabiddanda.bsky.social for all their work on this.
🧵 A thread on the key results and takeaways from our work:
Assembling unmapped reads reveals hidden variation in South Asian genomes https://www.biorxiv.org/content/10.1101/2025.05.14.653340v1
May 15, 2025 at 3:27 PM
Hire him!! You won’t regret it!!!
Reposted by Radhika Jangi
If you are here at #bog25 please check out my poster (number 87) tonight! 😁 Showing our work on common variation associated with aneuploidy in human embryos
May 7, 2025 at 5:26 PM
If you are here at #bog25 please check out my poster (number 87) tonight! 😁 Showing our work on common variation associated with aneuploidy in human embryos
Reposted by Radhika Jangi
Excited to share our latest work on comparing and visualizing multiple genome assemblies to identify conservation and structural variation in pangenomes with Mumemto! Check out poster 250 at #bog25 if you are here. New preprint coming very soon 👀
May 9, 2025 at 4:26 PM
Excited to share our latest work on comparing and visualizing multiple genome assemblies to identify conservation and structural variation in pangenomes with Mumemto! Check out poster 250 at #bog25 if you are here. New preprint coming very soon 👀
Amazing work by my buddy and colleague @supmerlin.bsky.social and Wenhe identifying treatment response specific and dynamic effects of genetic regulation in developmental contexts!!
1/n 🚨Very excited to share our recent work!🚨
To understand gene regulation across diverse environmental conditions and cellular contexts, we treated a broad array of human cell types with three environmental exposures in vitro.
www.biorxiv.org/content/10.1...
To understand gene regulation across diverse environmental conditions and cellular contexts, we treated a broad array of human cell types with three environmental exposures in vitro.
www.biorxiv.org/content/10.1...
May 5, 2025 at 7:13 PM
Amazing work by my buddy and colleague @supmerlin.bsky.social and Wenhe identifying treatment response specific and dynamic effects of genetic regulation in developmental contexts!!
Extremely hirable guy 10/10
I'll also be on the job market this summer, so please reach out if you're interested!
You can find out more about me at these links:
LinkedIn: www.linkedin.com/in/arun96/
Personal Website: arundas.org
You can find out more about me at these links:
LinkedIn: www.linkedin.com/in/arun96/
Personal Website: arundas.org
Arun Das
arundas.org
April 22, 2025 at 1:31 PM
Extremely hirable guy 10/10
Reposted by Radhika Jangi
Hello Bluesky 👋🏾
I’m going to be defending my thesis on Wednesday, so I thought this was as good a time as any to introduce myself and my work.
I’m Arun Das, I’m a PhD student in Schatz Lab @ JHU, and my work broadly focuses on algorithms to improve accessibility and representation in genomics.
I’m going to be defending my thesis on Wednesday, so I thought this was as good a time as any to introduce myself and my work.
I’m Arun Das, I’m a PhD student in Schatz Lab @ JHU, and my work broadly focuses on algorithms to improve accessibility and representation in genomics.
April 21, 2025 at 9:24 PM
Hello Bluesky 👋🏾
I’m going to be defending my thesis on Wednesday, so I thought this was as good a time as any to introduce myself and my work.
I’m Arun Das, I’m a PhD student in Schatz Lab @ JHU, and my work broadly focuses on algorithms to improve accessibility and representation in genomics.
I’m going to be defending my thesis on Wednesday, so I thought this was as good a time as any to introduce myself and my work.
I’m Arun Das, I’m a PhD student in Schatz Lab @ JHU, and my work broadly focuses on algorithms to improve accessibility and representation in genomics.
Reposted by Radhika Jangi
Thrilled to see this work out - its been fascinating to look at statistical genetics in these IVF embryo datasets underlying meiotic aneuploidies and recombination! Joint work led with @saracarioscia.bsky.social. See thread below, thoughts welcome!
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
April 7, 2025 at 2:27 PM
Thrilled to see this work out - its been fascinating to look at statistical genetics in these IVF embryo datasets underlying meiotic aneuploidies and recombination! Joint work led with @saracarioscia.bsky.social. See thread below, thoughts welcome!
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Radhika Jangi
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
April 7, 2025 at 2:01 PM
Aneuploidy is the leading cause of pregnancy loss. In work led by @saracarioscia.bsky.social and @aabiddanda.bsky.social, we reanalyzed genetic testing data from 139,416 IVF embryos to discover variants associated with recombination phenotypes and aneuploidy risk. www.medrxiv.org/content/10.1...
Reposted by Radhika Jangi
My main PhD work is up! See thread below. I would love to discuss! www.medrxiv.org/content/10.1...
April 7, 2025 at 2:20 PM
My main PhD work is up! See thread below. I would love to discuss! www.medrxiv.org/content/10.1...
Reposted by Radhika Jangi
Happy to share our work characterizing functional rare SVs in rare diseases with long-read genome sequencing and transcriptomic outlier data: genome.cshlp.org/content/earl...
Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
genome.cshlp.org
March 26, 2025 at 2:30 PM
Happy to share our work characterizing functional rare SVs in rare diseases with long-read genome sequencing and transcriptomic outlier data: genome.cshlp.org/content/earl...
Reposted by Radhika Jangi
This is possible because we can now merge new assemblies as they are released easily without re-running Mumemto on the whole pangenome! We're just providing the non-zoomable image while we await the final HPRC publication. Preprint: www.biorxiv.org/content/10.1...
Github: github.com/vikshiv/mume...
Github: github.com/vikshiv/mume...
GitHub - vikshiv/mumemto: Mumemto: multi-MUM and MEM finding across pangenomes
Mumemto: multi-MUM and MEM finding across pangenomes - vikshiv/mumemto
github.com
February 26, 2025 at 6:01 PM
This is possible because we can now merge new assemblies as they are released easily without re-running Mumemto on the whole pangenome! We're just providing the non-zoomable image while we await the final HPRC publication. Preprint: www.biorxiv.org/content/10.1...
Github: github.com/vikshiv/mume...
Github: github.com/vikshiv/mume...
Reposted by Radhika Jangi
Fortunes at the Battle lab lunar near year celebration were on brand. Love the lab. Watch out for confounders this year everyone, and happy new year.
January 29, 2025 at 5:01 PM
Fortunes at the Battle lab lunar near year celebration were on brand. Love the lab. Watch out for confounders this year everyone, and happy new year.
Reposted by Radhika Jangi
Excited to share a preprint for (w/ @benlangmead.bsky.social) our new tool, Mumemto, on biorxiv! Mumemto finds multi-MUMs across pangenomes (i.e. mummer but for pangenomes). It can rapidly visualize synteny, identify misassemblies, and accelerate core genome and multiple alignment, highlighting SVs.
Mumemto: efficient maximal matching across pangenomes
Aligning genomes into common coordinates is central to pangenome analysis and construction, but it is also computationally expensive. Multi-sequence maximal unique matches (multi-MUMs) are guideposts ...
www.biorxiv.org
January 6, 2025 at 3:27 PM
Excited to share a preprint for (w/ @benlangmead.bsky.social) our new tool, Mumemto, on biorxiv! Mumemto finds multi-MUMs across pangenomes (i.e. mummer but for pangenomes). It can rapidly visualize synteny, identify misassemblies, and accelerate core genome and multiple alignment, highlighting SVs.