George Schaible
@quantaofgeorge.bsky.social
PhD / postdoc at UC Santa Barbara / marine microbiology / building methods and techniques to study microbial dark matter / Erdos # = 5
Reposted by George Schaible
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
November 12, 2025 at 10:31 AM
What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
It's *scientific publishing*.
We call this the Drain of Scientific Publishing.
Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...
Thread @markhanson.fediscience.org.ap.brid.gy 👇
Reposted by George Schaible
Reposted by George Schaible
How “intelligent” is a slime mold? When it solves mazes, it might not be thinking:it’s obeying physics. Our new paper with
@jordiplam.bsky.social shows how it follows a least action principle,letting physics do the job arxiv.org/pdf/2511.08531
@drmichaellevin.bsky.social @docteur-drey.bsky.social
@jordiplam.bsky.social shows how it follows a least action principle,letting physics do the job arxiv.org/pdf/2511.08531
@drmichaellevin.bsky.social @docteur-drey.bsky.social
November 12, 2025 at 4:17 AM
How “intelligent” is a slime mold? When it solves mazes, it might not be thinking:it’s obeying physics. Our new paper with
@jordiplam.bsky.social shows how it follows a least action principle,letting physics do the job arxiv.org/pdf/2511.08531
@drmichaellevin.bsky.social @docteur-drey.bsky.social
@jordiplam.bsky.social shows how it follows a least action principle,letting physics do the job arxiv.org/pdf/2511.08531
@drmichaellevin.bsky.social @docteur-drey.bsky.social
Reposted by George Schaible
Friday means a new #MattersMicrobial podcast. This week, Dr. Hannah Ledvina joins the #QualityQuorum to chat about how bacteria can shield themselves against Bdellovibrio attack! Please spread the #GoodMicrobialWord. @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/n31kkw576GE?...
youtu.be/n31kkw576GE?...
November 7, 2025 at 6:03 PM
Friday means a new #MattersMicrobial podcast. This week, Dr. Hannah Ledvina joins the #QualityQuorum to chat about how bacteria can shield themselves against Bdellovibrio attack! Please spread the #GoodMicrobialWord. @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/n31kkw576GE?...
youtu.be/n31kkw576GE?...
Reposted by George Schaible
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Ever wondered what your genome might say if you could talk to it? As @microyunha.bsky.social puts it, SeqHub lets you “chat with your genome.”
We're thrilled to announce SeqHub, an AI-enabled platform for biological sequence analysis. SeqHub brings together sequence search, genome annotation, and data sharing in one place.
November 7, 2025 at 8:06 AM
Ever wondered what your genome might say if you could talk to it? As @microyunha.bsky.social puts it, SeqHub lets you “chat with your genome.”
Reposted by George Schaible
We're thrilled to announce SeqHub, an AI-enabled platform for biological sequence analysis. SeqHub brings together sequence search, genome annotation, and data sharing in one place.
October 28, 2025 at 1:47 PM
We're thrilled to announce SeqHub, an AI-enabled platform for biological sequence analysis. SeqHub brings together sequence search, genome annotation, and data sharing in one place.
Reposted by George Schaible
Reposted by George Schaible
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
October 28, 2025 at 3:07 PM
Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
Reposted by George Schaible
A professor of mine once said that learning stops once the answer is given.
When people learn with ChatGPT instead of following their own searches, they end up knowing less, caring less, and producing worse advice, even when the facts are the same.
Friction is an essential ingredient for learning! Convenience makes us shallow.
academic.oup.com/pnasnexus/ar...
Friction is an essential ingredient for learning! Convenience makes us shallow.
academic.oup.com/pnasnexus/ar...
Experimental evidence of the effects of large language models versus web search on depth of learning
Abstract. The effects of using large language models (LLMs) versus traditional web search on depth of learning are explored. A theory is proposed that when
academic.oup.com
October 28, 2025 at 8:18 PM
A professor of mine once said that learning stops once the answer is given.
Reposted by George Schaible
It’s Friday! This time, Dr. Joshua Shrout of Notre Dame joins the #QualityQuorum to discuss sociomicrobiology on #MattersMicrobial. Don’t miss this one! Please spread the #GoodMicrobialWord @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/b2UjnoM2VgU?...
youtu.be/b2UjnoM2VgU?...
October 24, 2025 at 4:56 PM
It’s Friday! This time, Dr. Joshua Shrout of Notre Dame joins the #QualityQuorum to discuss sociomicrobiology on #MattersMicrobial. Don’t miss this one! Please spread the #GoodMicrobialWord @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/b2UjnoM2VgU?...
youtu.be/b2UjnoM2VgU?...
Reposted by George Schaible
Balancing stability and flexibility when reshaping archaeal membranes.
buff.ly/4yqUdBj
buff.ly/4yqUdBj
October 15, 2025 at 7:11 PM
Balancing stability and flexibility when reshaping archaeal membranes.
buff.ly/4yqUdBj
buff.ly/4yqUdBj
Reposted by George Schaible
Joel Mokyr, Philippe Aghion and Pewter Howitt share economics prize for work that underlines the importance of investing in research and development.
go.nature.com/4hj9NNV
go.nature.com/4hj9NNV
Economics Nobel prize won by researchers who showed how science boosts growth
Joel Mokyr, Philippe Aghion and Pewter Howitt share economics prize for work that underlines the importance of investing in research and development.
go.nature.com
October 13, 2025 at 8:37 PM
Joel Mokyr, Philippe Aghion and Pewter Howitt share economics prize for work that underlines the importance of investing in research and development.
go.nature.com/4hj9NNV
go.nature.com/4hj9NNV
Reposted by George Schaible
Metabolic capacity is maintained despite shifts in microbial diversity in estuary sediments academic.oup.com/ismecommun/a...
Metabolic capacity is maintained despite shifts in microbial diversity in estuary sediments
Abstract. Estuaries are highly productive ecosystems where microbial communities drive nutrient and carbon cycling, supporting complex food webs. With inte
academic.oup.com
October 11, 2025 at 5:52 PM
Metabolic capacity is maintained despite shifts in microbial diversity in estuary sediments academic.oup.com/ismecommun/a...
Reposted by George Schaible
#inktober day 2 with #Weave
Cyanobacteria form interwoven patterns.
The micrographs from paper by J. Cammann et al, in Nat. Comm. Physics (2024) inspired me.
Today was less about googly eyes and more about focusing on the feel of my pens. Having fun by playing with different brush and pen sizes.
Cyanobacteria form interwoven patterns.
The micrographs from paper by J. Cammann et al, in Nat. Comm. Physics (2024) inspired me.
Today was less about googly eyes and more about focusing on the feel of my pens. Having fun by playing with different brush and pen sizes.
October 2, 2025 at 10:53 PM
Reposted by George Schaible
Looking for a cutting-edge and fun conference in 2026?
How about:
GRC Geobiology in Ventura, CA - January 11-16, 2026
www.grc.org/geobiology-c...
AbSciCon in Madison, WI - May 17-22, 2026
www.agu.org/abscicon
🤩The Ruff Lab will be there with sessions and presentations on Dark Oxygen Production 🥳
How about:
GRC Geobiology in Ventura, CA - January 11-16, 2026
www.grc.org/geobiology-c...
AbSciCon in Madison, WI - May 17-22, 2026
www.agu.org/abscicon
🤩The Ruff Lab will be there with sessions and presentations on Dark Oxygen Production 🥳
2026 Geobiology Conference GRC
The 2026 Gordon Research Conference on Geobiology will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
October 6, 2025 at 11:15 PM
Looking for a cutting-edge and fun conference in 2026?
How about:
GRC Geobiology in Ventura, CA - January 11-16, 2026
www.grc.org/geobiology-c...
AbSciCon in Madison, WI - May 17-22, 2026
www.agu.org/abscicon
🤩The Ruff Lab will be there with sessions and presentations on Dark Oxygen Production 🥳
How about:
GRC Geobiology in Ventura, CA - January 11-16, 2026
www.grc.org/geobiology-c...
AbSciCon in Madison, WI - May 17-22, 2026
www.agu.org/abscicon
🤩The Ruff Lab will be there with sessions and presentations on Dark Oxygen Production 🥳
Reposted by George Schaible
1/ We’re delighted to hear that our Reviewing Editor, Shimon Sakaguchi, has been awarded the 2025 Nobel Prize in Physiology and Medicine today alongside colleagues Fred Ramsdell and Mary Brunkell: www.nobelprize.org
The official website of the Nobel Prize - NobelPrize.org
The Nobel Prize rewards science, humanism and peace efforts. This is one of the central concepts in the will of Alfred Nobel, and it also permeates the outreach activities that have been developed for...
www.nobelprize.org
October 6, 2025 at 3:07 PM
1/ We’re delighted to hear that our Reviewing Editor, Shimon Sakaguchi, has been awarded the 2025 Nobel Prize in Physiology and Medicine today alongside colleagues Fred Ramsdell and Mary Brunkell: www.nobelprize.org
Reposted by George Schaible
And children are dying from lack of access to medicine because he spent a weekend “feeding USAID into the woodchipper”
Elon Musk becomes the first person in history to be worth half a trillion dollars.
Elon Musk becomes first person to hit $500 billion in net worth
Oracle CEO Larry Ellison briefly eclipsed Musk as the world's richest person last month.
www.axios.com
October 1, 2025 at 9:12 PM
And children are dying from lack of access to medicine because he spent a weekend “feeding USAID into the woodchipper”
Reposted by George Schaible
"Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91"
[gift link, free to read]
www.nytimes.com/2025/10/01/o...
[gift link, free to read]
www.nytimes.com/2025/10/01/o...
Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91
www.nytimes.com
October 1, 2025 at 6:54 PM
"Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91"
[gift link, free to read]
www.nytimes.com/2025/10/01/o...
[gift link, free to read]
www.nytimes.com/2025/10/01/o...
Ruger keeps steeling my phone an taking selfies 🤳
September 30, 2025 at 5:29 AM
Ruger keeps steeling my phone an taking selfies 🤳
Reposted by George Schaible
Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
High-accuracy SNV calling for bacterial isolates using deep learning with AccuSNV
Accurate detection of mutations within bacterial species is critical for fundamental studies of microbial evolution, reconstructing transmission events, and identifying antimicrobial resistance mutati...
www.biorxiv.org
September 29, 2025 at 7:45 PM
Precisely calling mutations across hundreds of bacterial isolates has been hard, requiring manual filtering and expertise.
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
Until now, using AccuSNV.
Herui Liao trained an ML model based on our previous meticulously called SNVs.
www.biorxiv.org/content/10.1...
Reposted by George Schaible
... it's quite common that data consumers download public sequences, run some new bioinformatic tools and publish new exciting results. It's good for these data recyclers 🎖️, but quite sad 😭for the PhD student - the data creator, who doesn't get any recognition for their previous huge effort...🧵
September 29, 2025 at 10:56 AM
... it's quite common that data consumers download public sequences, run some new bioinformatic tools and publish new exciting results. It's good for these data recyclers 🎖️, but quite sad 😭for the PhD student - the data creator, who doesn't get any recognition for their previous huge effort...🧵
Reposted by George Schaible
Our article on equitable reuse of public sequencing data is out! Led by @alexjprobst.bsky.social, @lhug.bsky.social, Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and myself -, co-authored by Anke Heyder, and developed in consultation with 167 scientists. tinyurl.com/n6yeanmk
A roadmap for equitable reuse of public microbiome data - Nature Microbiology
In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.
tinyurl.com
September 26, 2025 at 8:14 PM
Our article on equitable reuse of public sequencing data is out! Led by @alexjprobst.bsky.social, @lhug.bsky.social, Cristina Moraru, @geomicrosoares.bsky.social, @folker.bsky.social and myself -, co-authored by Anke Heyder, and developed in consultation with 167 scientists. tinyurl.com/n6yeanmk
Check out the new community roadmap for equitable sequence data reuse. With 160+ scientists, a proposed “Data Reuse Information” tags to modernize outdated guidelines and foster collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A roadmap for equitable reuse of public microbiome data - Nature Microbiology
In this Consensus Statement, a consortium of microbiome scientists discuss current sequencing data sharing policies and propose the use of a Data Reuse Information (DRI) tag to promote equitable and collaborative data sharing.
www.nature.com
September 27, 2025 at 9:27 PM
Check out the new community roadmap for equitable sequence data reuse. With 160+ scientists, a proposed “Data Reuse Information” tags to modernize outdated guidelines and foster collaboration.
www.nature.com/articles/s41...
www.nature.com/articles/s41...