Dr Pierre Talbot
@pierretalbot.bsky.social
Immunology - Professor - Research involves: Characterization of molecular and cellular interactions between human coronaviruses HCoVs (common cold viruses) with the immune and nervous systems. https://tinyurl.com/neuroinflammation
Pinned
Marc Veldhoen est un psychopathe, pas un physicien.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
Congratulations on the publication. We will eventually need to care about all viruses to protect our brains.
"Memory impairment was induced by infection with either HSV-1 or HSV-2 wild-type viruses, indicating that the cognitive impairment associated with neonatal infection was not strain-specific"
"Memory impairment was induced by infection with either HSV-1 or HSV-2 wild-type viruses, indicating that the cognitive impairment associated with neonatal infection was not strain-specific"
Asymptomatic neonatal herpes simplex virus infection in mice leads to long-term cognitive impairment https://www.biorxiv.org/content/10.1101/2024.04.22.590596v1
Asymptomatic neonatal herpes simplex virus infection in mice leads to long-term cognitive impairment https://www.biorxiv.org/content/10.1101/2024.04.22.590596v1
Neonatal herpes simplex virus (nHSV) is a devastating infection impacting approximately 14,000 newbo
www.biorxiv.org
February 11, 2025 at 6:11 PM
Congratulations on the publication. We will eventually need to care about all viruses to protect our brains.
"Memory impairment was induced by infection with either HSV-1 or HSV-2 wild-type viruses, indicating that the cognitive impairment associated with neonatal infection was not strain-specific"
"Memory impairment was induced by infection with either HSV-1 or HSV-2 wild-type viruses, indicating that the cognitive impairment associated with neonatal infection was not strain-specific"
"However, Long COVID is not a mystery. Research increasingly links the condition and its symptoms to persistent SARS-CoV-2 infection, with evidence showing that the virus can linger in reservoirs for months, or even years, in at least a subset of individuals"
1/ Cutting-edge Recommendations Provide Treatment Path for Millions of Long COVID Patients
In a new report, global experts outline key considerations to address persistent SARS-CoV-2; provide a
roadmap to test critical new long COVID therapies
polybio.org/cutting-edge...
In a new report, global experts outline key considerations to address persistent SARS-CoV-2; provide a
roadmap to test critical new long COVID therapies
polybio.org/cutting-edge...
Cutting-edge Recommendations Provide Treatment Path for Millions of Long COVID Patients - PolyBio Research Foundation
In a new report, global experts outline key considerations to address persistent SARS-CoV-2; provide a roadmap to test critical new long...
polybio.org
February 11, 2025 at 5:03 PM
"However, Long COVID is not a mystery. Research increasingly links the condition and its symptoms to persistent SARS-CoV-2 infection, with evidence showing that the virus can linger in reservoirs for months, or even years, in at least a subset of individuals"
We have decades of #Alzheimers #Parkinsons and #MultipleSclerois knowledge that characterize how various cellular pathways that link the immune system and various autoimmune dysfunction, triggering neuroinflammation. 1/2
#LongCOVID #COVID19 #MedSky
www.eurekalert.org/news-release...
#LongCOVID #COVID19 #MedSky
www.eurekalert.org/news-release...
Biomarker test can detect Alzheimer's pathology earlier, Pitt study shows
Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the ...
www.eurekalert.org
February 11, 2025 at 2:50 PM
We have decades of #Alzheimers #Parkinsons and #MultipleSclerois knowledge that characterize how various cellular pathways that link the immune system and various autoimmune dysfunction, triggering neuroinflammation. 1/2
#LongCOVID #COVID19 #MedSky
www.eurekalert.org/news-release...
#LongCOVID #COVID19 #MedSky
www.eurekalert.org/news-release...
Reposted by Dr Pierre Talbot
He is so right.
The next 4-5 years are going to be unhinged. It'll take decades to restore and repair the damage to Public Health.
February 11, 2025 at 12:38 PM
He is so right.
New research examines prescribing oral antivirals against COVID-19. Conclusion: Oral COVID-19 antivirals are a key tool in managing symptoms, especially #LongCOVID. Access to testing and healthcare remains vital for equitable care.
#HealthcareAccess #COVID19
www.publish.csiro.au/py/Fulltext/...
#HealthcareAccess #COVID19
www.publish.csiro.au/py/Fulltext/...
Oral COVID-19 antiviral prescribing in Australian general practice – a retrospective observational study
Background This study aimed to gain a comprehensive understanding of oral COVID-19 antiviral prescribing in Australian general practice.Methods The study was a retrospective observational cohort study...
www.publish.csiro.au
February 11, 2025 at 12:45 PM
New research examines prescribing oral antivirals against COVID-19. Conclusion: Oral COVID-19 antivirals are a key tool in managing symptoms, especially #LongCOVID. Access to testing and healthcare remains vital for equitable care.
#HealthcareAccess #COVID19
www.publish.csiro.au/py/Fulltext/...
#HealthcareAccess #COVID19
www.publish.csiro.au/py/Fulltext/...
Le SRAS n'a jamais risqué d'entraîner la mort après une seule infection. Le SRAS possède une adaptation unique de l'immunité humaine qui permet des infections multiples et répétées. La destruction du système immunitaire et les infections opportunistes bactériennes constituent le danger du SRAS.
You know after I saw that T cells dipped due to C19 I said I’m expecting TB prevalence to go up.
Guess what’s happening… in multiple locations…
Guess what’s happening… in multiple locations…
February 11, 2025 at 12:22 PM
Le SRAS n'a jamais risqué d'entraîner la mort après une seule infection. Le SRAS possède une adaptation unique de l'immunité humaine qui permet des infections multiples et répétées. La destruction du système immunitaire et les infections opportunistes bactériennes constituent le danger du SRAS.
Marc Veldhoen est un psychopathe, pas un physicien.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
February 11, 2025 at 12:14 PM
Marc Veldhoen est un psychopathe, pas un physicien.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
Des influenceurs de médias sociaux qui ne sont pas immunologistes et des comptes prétendant être immunologistes ont bloqué notre compte et nous ont déclarés morts. Ce qui est incroyablement amusant.
Reposted by Dr Pierre Talbot
Culling the herd. Eugenics through inaction and neglect. Many governments did the math and decided to let people get a novel virus repeatedly until “the weak” were removed (bonus, no need to pay pensions). Not caring that “novel” means unknown. The impact on our young, our future, is incalculable.
Eradicating the Baby Boomer generation provided and continues to provide extensive financial returns. Offering the elderly safety has a negative financial incentive. The UK's politicians have admitted to murder but none of them are facing murder charges.
#FlattenTheBoomers #EpiSky #PublicHealth
#FlattenTheBoomers #EpiSky #PublicHealth
Anika Wells downplayed rising COVID-19 deaths in aged care, blaming community spread and relaxed lockdowns, shifting focus to residents’ preferences rather than government responsibility.🤦♂️
February 11, 2025 at 12:21 AM
Culling the herd. Eugenics through inaction and neglect. Many governments did the math and decided to let people get a novel virus repeatedly until “the weak” were removed (bonus, no need to pay pensions). Not caring that “novel” means unknown. The impact on our young, our future, is incalculable.
The tragedy of abandoning everyone to take individual precautions is underfunded primary care. Without proper access to physicians there is an escalating and incremental cost when any diagnosis and treatment is delayed, especially #LongCOVID. #PublicHealth #EpiSky
www.cidrap.umn.edu/covid-19/pri...
www.cidrap.umn.edu/covid-19/pri...
Primary care less accessible during COVID, but some practice types adapted more easily
www.cidrap.umn.edu
February 10, 2025 at 8:52 PM
The tragedy of abandoning everyone to take individual precautions is underfunded primary care. Without proper access to physicians there is an escalating and incremental cost when any diagnosis and treatment is delayed, especially #LongCOVID. #PublicHealth #EpiSky
www.cidrap.umn.edu/covid-19/pri...
www.cidrap.umn.edu/covid-19/pri...
Reposted by Dr Pierre Talbot
The Survival Guide you didn’t know you needed
threadreaderapp.com/thread/18888...
threadreaderapp.com/thread/18888...
Thread by @drseanmullen on Thread Reader App
@drseanmullen: Covid Cautious Survival Guide: The Terms You Forgot (Or Never Knew) A field guide to navigating the pandemic reality everyone wants to ignore. 1. The Basics: FAFO Edition - FAFO (Fuck A...
threadreaderapp.com
February 10, 2025 at 6:16 PM
The Survival Guide you didn’t know you needed
threadreaderapp.com/thread/18888...
threadreaderapp.com/thread/18888...
It's not everyone ... but even when a scientist asks to back up a statement of fact, they are:
- not being honest
- seeking to waste time
- debating a position without backing up their position
- without ability to be swayed to consider or accept your position - or they would go find the data.
- not being honest
- seeking to waste time
- debating a position without backing up their position
- without ability to be swayed to consider or accept your position - or they would go find the data.
The problem is you assume they want to "engage and have reals discussions on real issues." They don't. When confronted with facts, data, science, actual laws, and the like, they resort to spewing lies, disinformation and hate.
February 10, 2025 at 8:05 PM
It's not everyone ... but even when a scientist asks to back up a statement of fact, they are:
- not being honest
- seeking to waste time
- debating a position without backing up their position
- without ability to be swayed to consider or accept your position - or they would go find the data.
- not being honest
- seeking to waste time
- debating a position without backing up their position
- without ability to be swayed to consider or accept your position - or they would go find the data.
1/10 🧵
New research shows 1.5 million kids with documented COVID-19 face a 25% higher risk of GI symptoms like abdominal pain & diarrhea for up to 2 years. But what about kids who were infected but never tested?
Let’s break it down.
#LongCOVID #Pediatrics #MedSky
www.cidrap.umn.edu/covid-19/aft...
New research shows 1.5 million kids with documented COVID-19 face a 25% higher risk of GI symptoms like abdominal pain & diarrhea for up to 2 years. But what about kids who were infected but never tested?
Let’s break it down.
#LongCOVID #Pediatrics #MedSky
www.cidrap.umn.edu/covid-19/aft...
After COVID-19, kids more likely to have GI symptoms for up to 2 years
www.cidrap.umn.edu
February 10, 2025 at 7:22 PM
1/10 🧵
New research shows 1.5 million kids with documented COVID-19 face a 25% higher risk of GI symptoms like abdominal pain & diarrhea for up to 2 years. But what about kids who were infected but never tested?
Let’s break it down.
#LongCOVID #Pediatrics #MedSky
www.cidrap.umn.edu/covid-19/aft...
New research shows 1.5 million kids with documented COVID-19 face a 25% higher risk of GI symptoms like abdominal pain & diarrhea for up to 2 years. But what about kids who were infected but never tested?
Let’s break it down.
#LongCOVID #Pediatrics #MedSky
www.cidrap.umn.edu/covid-19/aft...
Hit & Run
Respiratory viruses and HCoVs in particular can cause significant accumulation of misfolded proteins in the immuno-naïve regions of the CNS. We don't have a cure for #Alzheimers because we do not have medicine that resolves these fibrinogen. #LongCOVID causes neuroinflammation.
Respiratory viruses and HCoVs in particular can cause significant accumulation of misfolded proteins in the immuno-naïve regions of the CNS. We don't have a cure for #Alzheimers because we do not have medicine that resolves these fibrinogen. #LongCOVID causes neuroinflammation.
Blood biomarkers in a middle-aged population suggest that SARS-CoV-2 infection is associated with greater brain β-amyloid plaque accumulation. The findings published in Nature Medicine suggest that SARS-CoV-2 may increase the risk of future Alzheimer’s disease. #Medsky 🧪
Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection - Nature Medicine
Blood biomarkers in a middle-aged population suggest that SARS-CoV-2 infection is associated with greater brain β-amyloid plaque accumulation.
go.nature.com
February 10, 2025 at 6:58 PM
Hit & Run
Respiratory viruses and HCoVs in particular can cause significant accumulation of misfolded proteins in the immuno-naïve regions of the CNS. We don't have a cure for #Alzheimers because we do not have medicine that resolves these fibrinogen. #LongCOVID causes neuroinflammation.
Respiratory viruses and HCoVs in particular can cause significant accumulation of misfolded proteins in the immuno-naïve regions of the CNS. We don't have a cure for #Alzheimers because we do not have medicine that resolves these fibrinogen. #LongCOVID causes neuroinflammation.
Does this still occur often here?
Being blocked for challenging an incorrect statement by Edward Nirenberg that H5N1 is not neuroinvasive and the study didn't perform a neurological assessment?
Being blocked for challenging an incorrect statement by Edward Nirenberg that H5N1 is not neuroinvasive and the study didn't perform a neurological assessment?
The rest of your assessment was fine Edward.
Sorry if pointing out that neuroinvasive cannot be deduced from this study - to counter the decades of other evidence supporting H5N1 neuroinvasive research in humans - has upset you.
bsky.app/profile/enir...
Sorry if pointing out that neuroinvasive cannot be deduced from this study - to counter the decades of other evidence supporting H5N1 neuroinvasive research in humans - has upset you.
bsky.app/profile/enir...
February 10, 2025 at 1:43 PM
Does this still occur often here?
Being blocked for challenging an incorrect statement by Edward Nirenberg that H5N1 is not neuroinvasive and the study didn't perform a neurological assessment?
Being blocked for challenging an incorrect statement by Edward Nirenberg that H5N1 is not neuroinvasive and the study didn't perform a neurological assessment?
Eradicating the Baby Boomer generation provided and continues to provide extensive financial returns. Offering the elderly safety has a negative financial incentive. The UK's politicians have admitted to murder but none of them are facing murder charges.
#FlattenTheBoomers #EpiSky #PublicHealth
#FlattenTheBoomers #EpiSky #PublicHealth
Anika Wells downplayed rising COVID-19 deaths in aged care, blaming community spread and relaxed lockdowns, shifting focus to residents’ preferences rather than government responsibility.🤦♂️
Anika Wells deflects blame for rise in home care wait times and aged care Covid-19 deaths - Hellocare
Home care waitlists have increased from 6 months under Morrison to 12–18 months under Albanese and COVID-19 deaths in aged care are higher than they wore at the peak of the pandemic - yet Anika Wells ...
hellocare.com.au
February 10, 2025 at 12:35 PM
Eradicating the Baby Boomer generation provided and continues to provide extensive financial returns. Offering the elderly safety has a negative financial incentive. The UK's politicians have admitted to murder but none of them are facing murder charges.
#FlattenTheBoomers #EpiSky #PublicHealth
#FlattenTheBoomers #EpiSky #PublicHealth
Vaccines don't prevent #Alzheimers. Some doctors take #LongCOVID seriously, but others seem to think #COVID19 is still a 'common cold'. These physicians can't explain chronic brain fog. They can't solve the neurological damage so they don't admit SARS-CoV is neuroinvasive.
#NeuroCOVID #MedSky
#NeuroCOVID #MedSky
Both mild and severe cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are linked to changes in brain biomarkers associated with Alzheimer’s disease.
But let’s keep getting it over and over right ?
www.news-medical.net/news/2025020...
But let’s keep getting it over and over right ?
www.news-medical.net/news/2025020...
Does COVID increase the risk of Alzheimer’s disease?
COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years of aging. This study raises concerns about long-term neurological risks and ...
www.news-medical.net
February 10, 2025 at 12:27 PM
Vaccines don't prevent #Alzheimers. Some doctors take #LongCOVID seriously, but others seem to think #COVID19 is still a 'common cold'. These physicians can't explain chronic brain fog. They can't solve the neurological damage so they don't admit SARS-CoV is neuroinvasive.
#NeuroCOVID #MedSky
#NeuroCOVID #MedSky
Vaccines don't prevent #Alzheimers. Some doctors take #LongCOVID seriously, but other doctors seem to think #COVID19 is still a 'common cold'. These physicians can't explain chronic brain fog. They can't solve the neurological damage so they don't admit SARS-CoV is neuroinvasive.
#NeuroCOVID
#NeuroCOVID
Kids getting COVID repeatedly in school—is it a future Alzheimer’s crisis?
New research links even mild COVID to brain changes associated with Alzheimer’s. How will repeated infections affect their long-term brain health? #LongCovid #COVID19 #Alzheimers #SafeSchools
New research links even mild COVID to brain changes associated with Alzheimer’s. How will repeated infections affect their long-term brain health? #LongCovid #COVID19 #Alzheimers #SafeSchools
Both mild and severe cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are linked to changes in brain biomarkers associated with Alzheimer’s disease.
But let’s keep getting it over and over right ?
www.news-medical.net/news/2025020...
But let’s keep getting it over and over right ?
www.news-medical.net/news/2025020...
February 10, 2025 at 12:25 PM
Vaccines don't prevent #Alzheimers. Some doctors take #LongCOVID seriously, but other doctors seem to think #COVID19 is still a 'common cold'. These physicians can't explain chronic brain fog. They can't solve the neurological damage so they don't admit SARS-CoV is neuroinvasive.
#NeuroCOVID
#NeuroCOVID
Human Coronavirus (HCoV) infection #LongCOVID causing certain neurological diseases 5-10 years after the acute phase, leading to #Alzheimers #Parkinsons and #MultipleSclerosis
Neuro inflammation is a Hit & Run disease.
Neuro inflammation is a Hit & Run disease.
A fantastic new study in @cp-cellhostmicrobe.bsky.social led by @erturklab.bsky.social reveals that SARS-CoV-2 S1 protein can accumulate in the brain for years, potentially contributing to #LongCOVID symptoms. Happy to see our 🦙 #sdAb ( #nanobody) as a key reagent here: doi.org/10.1016/j.ch...
February 7, 2025 at 9:05 PM
Human Coronavirus (HCoV) infection #LongCOVID causing certain neurological diseases 5-10 years after the acute phase, leading to #Alzheimers #Parkinsons and #MultipleSclerosis
Neuro inflammation is a Hit & Run disease.
Neuro inflammation is a Hit & Run disease.
"Antibodies aren’t everything"
It's concerning to still see so many researchers and physicians get the function of HCoV antibodies wrong.
www.nature.com/articles/d41...
It's concerning to still see so many researchers and physicians get the function of HCoV antibodies wrong.
www.nature.com/articles/d41...
Four lessons COVID taught us about the immune system
In the midst of pandemic upheaval, researchers have gained fundamental insights about how the body fends off infections.
www.nature.com
February 7, 2025 at 7:50 PM
"Antibodies aren’t everything"
It's concerning to still see so many researchers and physicians get the function of HCoV antibodies wrong.
www.nature.com/articles/d41...
It's concerning to still see so many researchers and physicians get the function of HCoV antibodies wrong.
www.nature.com/articles/d41...
"Our data from this post hoc case–control matched study thus provide observational biomarker evidence that SARS-CoV infection can be associated with greater brain β-amyloid pathology in older adults."
SARS-CoV infection increases the risk of Alzheimer’s.
#Alzheimers
www.nature.com/articles/s41...
SARS-CoV infection increases the risk of Alzheimer’s.
#Alzheimers
www.nature.com/articles/s41...
Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection - Nature Medicine
Blood biomarkers in a middle-aged population suggest that SARS-CoV-2 infection is associated with greater brain β-amyloid plaque accumulation.
www.nature.com
February 7, 2025 at 7:38 PM
"Our data from this post hoc case–control matched study thus provide observational biomarker evidence that SARS-CoV infection can be associated with greater brain β-amyloid pathology in older adults."
SARS-CoV infection increases the risk of Alzheimer’s.
#Alzheimers
www.nature.com/articles/s41...
SARS-CoV infection increases the risk of Alzheimer’s.
#Alzheimers
www.nature.com/articles/s41...
Reposted by Dr Pierre Talbot
"SARS-CoV-2 immune protection is shaped by a dynamic interaction between host immunity and viral evolution, leading to contrasting reinfection patterns"
= to #COVID behavior has been unpredictable so far. And yes, for actual scientists, we are studying the current stage of the pandemic. Is not over
= to #COVID behavior has been unpredictable so far. And yes, for actual scientists, we are studying the current stage of the pandemic. Is not over
February 6, 2025 at 10:28 PM
"SARS-CoV-2 immune protection is shaped by a dynamic interaction between host immunity and viral evolution, leading to contrasting reinfection patterns"
= to #COVID behavior has been unpredictable so far. And yes, for actual scientists, we are studying the current stage of the pandemic. Is not over
= to #COVID behavior has been unpredictable so far. And yes, for actual scientists, we are studying the current stage of the pandemic. Is not over