Pierpaolo Sorrentino
@pierpasorre.bsky.social
I am a Neurologist and an Engineer, mainly using systems neuroscience applied to Neurological diseases. I am a tenured Associate Professor, working at Aix-Marseille university & Sassari university.
Reposted by Pierpaolo Sorrentino
Stop by this afternoon to chat about community structure in the 🪰connectome!
📍ZZ2/PSTR368.03
📍ZZ2/PSTR368.03
November 18, 2025 at 4:39 PM
Stop by this afternoon to chat about community structure in the 🪰connectome!
📍ZZ2/PSTR368.03
📍ZZ2/PSTR368.03
Reposted by Pierpaolo Sorrentino
With deep gratitude to my extraordinary co-authors @MariannaAngiolelli, @FukaiTomoki, @GustavoDeco, @pierpasorre.bsky.social, and @davemomi.bsky.social
—this work would not have been possible without them.
Supported by the MSCA grant @ec.europa.eu and @upf.edu—more to come!
—this work would not have been possible without them.
Supported by the MSCA grant @ec.europa.eu and @upf.edu—more to come!
September 22, 2025 at 9:03 AM
With deep gratitude to my extraordinary co-authors @MariannaAngiolelli, @FukaiTomoki, @GustavoDeco, @pierpasorre.bsky.social, and @davemomi.bsky.social
—this work would not have been possible without them.
Supported by the MSCA grant @ec.europa.eu and @upf.edu—more to come!
—this work would not have been possible without them.
Supported by the MSCA grant @ec.europa.eu and @upf.edu—more to come!
Reposted by Pierpaolo Sorrentino
🧠 Join us for the Brain Models for Multimodal Integration Symposium!
📅 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event
Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.
📅 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event
Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.
September 5, 2025 at 3:20 PM
🧠 Join us for the Brain Models for Multimodal Integration Symposium!
📅 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event
Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.
📅 12 September 2025 | ⏰ 12:00–13:15 UTC | 🌐 Virtual Event
Thrilled to co-chair w/ @pierpasorre.bsky.social at the @ohbmofficial.bsky.social Satellite Meeting! Feat. D. Depannemaecker & @gianmarcoduma.bsky.social ma.bsky.social.
Reposted by Pierpaolo Sorrentino
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
September 5, 2025 at 2:59 AM
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
Reposted by Pierpaolo Sorrentino
📢 Preprint alert! 🧠💡
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
🔗 www.biorxiv.org/content/10.1...
A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧵
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
🔗 www.biorxiv.org/content/10.1...
A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧵
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
Motor imagery-based Brain-Computer Interfaces (BCIs) restore control in persons with motor impairments, but up to 30% of users struggle—a phenomenon known as “BCI inefficiency”. This study tackles a k...
www.biorxiv.org
August 27, 2025 at 10:55 AM
📢 Preprint alert! 🧠💡
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
🔗 www.biorxiv.org/content/10.1...
A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧵
Neuronal avalanches as a predictive biomarker for guiding tailored BCI training programs
🔗 www.biorxiv.org/content/10.1...
A great work led by Camilla Mannino w/ @pierpasorre.bsky.social & @neurodynamicslab.bsky.social! @nerv-lab.bsky.social @institutducerveau.bsky.social 🧵
Reposted by Pierpaolo Sorrentino
🧠 New Preprint out!
Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD).
Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD.
@pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...
Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD).
Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD.
@pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...
Brain Fluidity as a Functional Marker of Tau-Related Neurodegeneration in Alzheimer’s Disease
Alzheimer’s Disease (AD) is the most common form of dementia and one of the leading neurodegenerative disorders worldwide. Neurophysiopathologically, AD is characterized by neuronal death, accompanied...
www.medrxiv.org
July 23, 2025 at 10:34 AM
🧠 New Preprint out!
Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD).
Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD.
@pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...
Brain fluidity: a functional marker of neuronal death in Alzheimer’s disease (AD).
Our results highlight the link between dynamic brain connectivity disruptions and neurodegeneration in AD.
@pierpasorre.bsky.social @gianmarcoduma.bsky.social www.medrxiv.org/content/10.1...
Reposted by Pierpaolo Sorrentino
Beta burst waveforms in PD! We find that specific types of beta bursts are rate-modulated by l-dopa, and STN-cortical connectivity during these burst types is related to clinical improvement. Fantastic work by Hasnae Agouram with @pierpasorre.bsky.social 🧠📈
🚨
Levodopa increased burst waveform-specific connectivity between STN and the sensorimotor cortex, which correlated with medication related improvement.
Beta burst waveforms look like a promising biomarker candidate for both disease severity and treatment response.
www.medrxiv.org/content/10.1...
Levodopa increased burst waveform-specific connectivity between STN and the sensorimotor cortex, which correlated with medication related improvement.
Beta burst waveforms look like a promising biomarker candidate for both disease severity and treatment response.
www.medrxiv.org/content/10.1...
July 23, 2025 at 5:26 AM
Beta burst waveforms in PD! We find that specific types of beta bursts are rate-modulated by l-dopa, and STN-cortical connectivity during these burst types is related to clinical improvement. Fantastic work by Hasnae Agouram with @pierpasorre.bsky.social 🧠📈
Reposted by Pierpaolo Sorrentino
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
July 15, 2025 at 2:05 PM
Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milner’s legacy continues. @mcgill.ca @cusm-muhc.bsky.social
Reposted by Pierpaolo Sorrentino
In many brain areas, neuronal tuning is heterogeneous. But how does this diversity help behavior? We show how tuning diversity shapes representational geometry and boosts coding efficiency for perception in our new preprint: www.biorxiv.org/content/10.1...
(w/ @sueyeonchung.bsky.social&Tony Movshon)
(w/ @sueyeonchung.bsky.social&Tony Movshon)
Variations in neuronal selectivity create efficient representational geometries for perception
Our visual capabilities depend on neural response properties in visual areas of our brains. Neurons exhibit a wide variety of selective response properties, but the reasons for this diversity are unkn...
www.biorxiv.org
June 29, 2025 at 12:19 AM
In many brain areas, neuronal tuning is heterogeneous. But how does this diversity help behavior? We show how tuning diversity shapes representational geometry and boosts coding efficiency for perception in our new preprint: www.biorxiv.org/content/10.1...
(w/ @sueyeonchung.bsky.social&Tony Movshon)
(w/ @sueyeonchung.bsky.social&Tony Movshon)
Reposted by Pierpaolo Sorrentino
🧠 Want to understand how different higher-order methods compare in brain connectivity analysis?
Check out our new preprint — a fantastic collab with past & present NPL members @lordgrilo.bsky.social :
🔗 www.biorxiv.org/content/10.1...
A thread🧵
Check out our new preprint — a fantastic collab with past & present NPL members @lordgrilo.bsky.social :
🔗 www.biorxiv.org/content/10.1...
A thread🧵
June 27, 2025 at 7:47 AM
🧠 Want to understand how different higher-order methods compare in brain connectivity analysis?
Check out our new preprint — a fantastic collab with past & present NPL members @lordgrilo.bsky.social :
🔗 www.biorxiv.org/content/10.1...
A thread🧵
Check out our new preprint — a fantastic collab with past & present NPL members @lordgrilo.bsky.social :
🔗 www.biorxiv.org/content/10.1...
A thread🧵
Reposted by Pierpaolo Sorrentino
Congratulations to Marie-Constance Corsi recipient of this year’s Early Career Award! Dr. Corsi’s innovative work in the #BCI field is already making a big impact.
May 6, 2025 at 7:38 PM
Congratulations to Marie-Constance Corsi recipient of this year’s Early Career Award! Dr. Corsi’s innovative work in the #BCI field is already making a big impact.
Reposted by Pierpaolo Sorrentino
A new computer model of Parkinson's disease has been created by researchers in France and Italy and tested in a first small-scale patient trial.
Read more: www.ebrains.eu/news-and-eve...
Read more: www.ebrains.eu/news-and-eve...
May 27, 2025 at 9:10 AM
A new computer model of Parkinson's disease has been created by researchers in France and Italy and tested in a first small-scale patient trial.
Read more: www.ebrains.eu/news-and-eve...
Read more: www.ebrains.eu/news-and-eve...
Reposted by Pierpaolo Sorrentino
Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...
rt_neurocomp - réseau français de neurosciences computationnelles - subscribe
listes.services.cnrs.fr
May 2, 2025 at 12:03 PM
Researchers in France are working on creating a french network of researchers to organize interaction, communication and training in #Computational_Neuroscience. If you are a CompNeuro working in France, consider joining, and registering to our mailing list: listes.services.cnrs.fr/wws/subscrib...
Reposted by Pierpaolo Sorrentino
Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
April 24, 2025 at 8:42 PM
Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
Reposted by Pierpaolo Sorrentino
April 21, 2025 at 4:21 PM
Reposted by Pierpaolo Sorrentino
After a long journey, our paper is officially out in PNAS! 🚀 Huge thanks to the team — excited to finally share it with the world. Check it out: www.pnas.org/doi/10.1073/...
Mapping global brain reconfigurations following local targeted manipulations | PNAS
Understanding how localized brain interventions influence whole-brain dynamics is
essential for deciphering neural function and designing therapeut...
www.pnas.org
April 19, 2025 at 4:27 PM
After a long journey, our paper is officially out in PNAS! 🚀 Huge thanks to the team — excited to finally share it with the world. Check it out: www.pnas.org/doi/10.1073/...
Reposted by Pierpaolo Sorrentino
sometimes this is what neuroimaging feels like: www.science.org/doi/abs/10.1...
Chaos in the Brickyard
www.science.org
April 11, 2025 at 6:48 PM
sometimes this is what neuroimaging feels like: www.science.org/doi/abs/10.1...
Reposted by Pierpaolo Sorrentino
Open source is draining.
One's todo-list is open to world.
People seldom realize the cost of what they get for free.
Unpleasant comments do happen.
Cost of maintenance is not understood.
opensource.com/article/17/2...
One's todo-list is open to world.
People seldom realize the cost of what they get for free.
Unpleasant comments do happen.
Cost of maintenance is not understood.
opensource.com/article/17/2...
March 22, 2025 at 3:53 PM
Open source is draining.
One's todo-list is open to world.
People seldom realize the cost of what they get for free.
Unpleasant comments do happen.
Cost of maintenance is not understood.
opensource.com/article/17/2...
One's todo-list is open to world.
People seldom realize the cost of what they get for free.
Unpleasant comments do happen.
Cost of maintenance is not understood.
opensource.com/article/17/2...
Reposted by Pierpaolo Sorrentino
🧵 How do psychedelics shape brain activity?
Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states.
Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d
A thread 🧵👇 1/n
Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states.
Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d
A thread 🧵👇 1/n
March 17, 2025 at 11:29 AM
🧵 How do psychedelics shape brain activity?
Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states.
Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d
A thread 🧵👇 1/n
Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states.
Title: Psychedelics Align Brain Activity with Context
Paper: lnkd.in/gt-kMR6d
A thread 🧵👇 1/n
Reposted by Pierpaolo Sorrentino
137 scientists from around the globe already signed up, what are you waiting for?
Friends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW!
woodstock.img.cas.cz
woodstock.img.cas.cz
March 14, 2025 at 1:58 PM
137 scientists from around the globe already signed up, what are you waiting for?
Reposted by Pierpaolo Sorrentino
This is a bright spot to start the day (on the West Coast, that is). The paper on "possibility space" with @laurennross.bsky.social and Viktor Jirsa is now published!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
The Possibility Space Concept in Neuroscience: Possibilities, Constraints, and Explanations
Although the brain is often characterized as a complex system, theoretical and philosophical frameworks often struggle to capture this. For example, mainstream mechanistic accounts model neural syste...
onlinelibrary.wiley.com
March 13, 2025 at 2:07 PM
This is a bright spot to start the day (on the West Coast, that is). The paper on "possibility space" with @laurennross.bsky.social and Viktor Jirsa is now published!
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Reposted by Pierpaolo Sorrentino
🚨 New paper on ArXiv:
“Uncertainty quantification and posterior sampling for network reconstruction”
TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics.
Short thread: 1/N
“Uncertainty quantification and posterior sampling for network reconstruction”
TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics.
Short thread: 1/N
March 12, 2025 at 11:57 AM
🚨 New paper on ArXiv:
“Uncertainty quantification and posterior sampling for network reconstruction”
TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics.
Short thread: 1/N
“Uncertainty quantification and posterior sampling for network reconstruction”
TL;DR; We present an efficient method to sample the entire ensemble of possible network reconstructions that are compatible with an indirect observation, e.g. a dynamics.
Short thread: 1/N
Reposted by Pierpaolo Sorrentino
Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025...
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️
March 11, 2025 at 3:02 PM
Cerebral blood perfusion across biological systems and the human lifespan | doi.org/10.1101/2025...
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️
How does blood perfusion map onto canonical features of brain structure and function? @asafarahani.bsky.social investigates ⤵️
Reposted by Pierpaolo Sorrentino
🚨 Preprint Alert 📝 🚨
Artificial Intelligence for automatic movement recognition: a network-based approach!
🔗 www.biorxiv.org/content/10.1...
A great collaboration with notably Emahnuel Troisi-Lopez & @pierpasorre.bsky.social! 🧵
Artificial Intelligence for automatic movement recognition: a network-based approach!
🔗 www.biorxiv.org/content/10.1...
A great collaboration with notably Emahnuel Troisi-Lopez & @pierpasorre.bsky.social! 🧵
Artificial Intelligence for automatic movement recognition: a network-based approach
Introduction automatic movement recognition is often used to support various fields such as clinical, sports, and security. To date, there is a lack of a classification feature that is both interpreta...
www.biorxiv.org
March 10, 2025 at 9:08 AM
🚨 Preprint Alert 📝 🚨
Artificial Intelligence for automatic movement recognition: a network-based approach!
🔗 www.biorxiv.org/content/10.1...
A great collaboration with notably Emahnuel Troisi-Lopez & @pierpasorre.bsky.social! 🧵
Artificial Intelligence for automatic movement recognition: a network-based approach!
🔗 www.biorxiv.org/content/10.1...
A great collaboration with notably Emahnuel Troisi-Lopez & @pierpasorre.bsky.social! 🧵
Reposted by Pierpaolo Sorrentino
Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...
March 6, 2025 at 7:16 PM
Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...