Piyush G.
@pg-pi3gey.bsky.social
Bioinformatics Engineer 🧬 | Tech 🖥️ | Gamer 🎮
Google introduced AlphaGenome: A new AI tool that predicts genetic variant impacts on gene regulation and disease biology, accelerating scientific discoveries! 🧬🔬 #AI #Genetics #Science #Technology
Read more:
deepmind.google/discover/blo...
Read more:
deepmind.google/discover/blo...
AlphaGenome: AI for better understanding the genome
Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function — now available via API.
deepmind.google
June 30, 2025 at 5:09 AM
Google introduced AlphaGenome: A new AI tool that predicts genetic variant impacts on gene regulation and disease biology, accelerating scientific discoveries! 🧬🔬 #AI #Genetics #Science #Technology
Read more:
deepmind.google/discover/blo...
Read more:
deepmind.google/discover/blo...
Reposted by Piyush G.
Breakthrough from Google DeepMind: AlphaGenome is Here 🧬
June 25, 2025 at 4:24 PM
Breakthrough from Google DeepMind: AlphaGenome is Here 🧬
Reposted by Piyush G.
Interesting... but we need better data for this to work www.nature.com/articles/d41... #genomics #artificialintelligence #dna #bioinformatics
DeepMind’s new AlphaGenome AI tackles the ‘dark matter’ in our DNA
Tool aims to solve the mystery of non-coding sequences — but is still in its infancy.
www.nature.com
June 25, 2025 at 8:36 PM
Interesting... but we need better data for this to work www.nature.com/articles/d41... #genomics #artificialintelligence #dna #bioinformatics
Reposted by Piyush G.
always always always run the sample data first when testing a new program #bioinformatics
June 2, 2025 at 5:34 PM
always always always run the sample data first when testing a new program #bioinformatics
It's great to see Windows Subsystem for Linux being open source by Microsoft! 🎉 I've been using WSL2 for my everyday Linux CLI tasks for Bioinformatics 🖥 🧬 – personally and professionally.
#WSL #OpenSource #Microsoft #Linux #Development #Technology
Blog Post: blogs.windows.com/windowsdevel...
#WSL #OpenSource #Microsoft #Linux #Development #Technology
Blog Post: blogs.windows.com/windowsdevel...
The Windows Subsystem for Linux is now open source
Today we’re very excited to announce the open-source release of the Windows Subsystem for Linux. This is the result of a multiyear effort to prepare for this, and a great closure to the first ever iss...
blogs.windows.com
May 21, 2025 at 5:25 AM
It's great to see Windows Subsystem for Linux being open source by Microsoft! 🎉 I've been using WSL2 for my everyday Linux CLI tasks for Bioinformatics 🖥 🧬 – personally and professionally.
#WSL #OpenSource #Microsoft #Linux #Development #Technology
Blog Post: blogs.windows.com/windowsdevel...
#WSL #OpenSource #Microsoft #Linux #Development #Technology
Blog Post: blogs.windows.com/windowsdevel...
Regeneron brought 23&Me customer data for $256M! 💰 This is HUGE for RWE data utilization, but will security & data privacy remain the same? 🤔 🧬 🖥 #Biotech #DataPrivacy #Investment #Healthcare #Technology
Full press release: investor.regeneron.com/news-release...
Full press release: investor.regeneron.com/news-release...
Regeneron Enters into Asset Purchase Agreement to Acquire 23andMe® for $256 Million; Plans to Maintain Consumer Genetics Business and Advance Shared Goals of Improving Human Health and Wellness | Rege...
Purchase is subject to bankruptcy court and regulatory approvals Regeneron will prioritize the privacy, security and ethical use of 23andMe’s customer data; stands ready to work with independent, cour...
investor.regeneron.com
May 19, 2025 at 5:48 PM
Regeneron brought 23&Me customer data for $256M! 💰 This is HUGE for RWE data utilization, but will security & data privacy remain the same? 🤔 🧬 🖥 #Biotech #DataPrivacy #Investment #Healthcare #Technology
Full press release: investor.regeneron.com/news-release...
Full press release: investor.regeneron.com/news-release...
Reposted by Piyush G.
🧪 The Arc Institute's Evo2 models DNA like an LLM models language, predicting mutations, gene function, and evolutionary signals. With 40B parameters trained on 128K genomes, it hints at AI-driven biological discovery. 🧬💻 #MLSky
Link to the paper: https://arcinstitute.org/manuscripts/Evo2
Link to the paper: https://arcinstitute.org/manuscripts/Evo2
AI can now model and design the genetic code for all domains of life with Evo 2 | Arc Institute
Arc Institute develops the largest AI model for biology to date in collaboration with NVIDIA, bringing together Stanford University, UC Berkeley, and UC San Francisco researchers
arcinstitute.org
February 24, 2025 at 3:15 PM
🧪 The Arc Institute's Evo2 models DNA like an LLM models language, predicting mutations, gene function, and evolutionary signals. With 40B parameters trained on 128K genomes, it hints at AI-driven biological discovery. 🧬💻 #MLSky
Link to the paper: https://arcinstitute.org/manuscripts/Evo2
Link to the paper: https://arcinstitute.org/manuscripts/Evo2
Reposted by Piyush G.
This a very important topic considering recent sudden dissappearance of Atlas Biomed, continuing problems at 23andMe, acquisition of Ancestry by an investment firm Blackstone, & multiple security incidents. #genomics #healthinformation
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Protecting Privacy When Genetic Databases Are Commercialized
This Viewpoint questions whether people’s health data obtained in direct-to-consumer genetic testing can be used, shared, or marketed in the future.
jamanetwork.com
January 10, 2025 at 8:38 AM
This a very important topic considering recent sudden dissappearance of Atlas Biomed, continuing problems at 23andMe, acquisition of Ancestry by an investment firm Blackstone, & multiple security incidents. #genomics #healthinformation
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Reposted by Piyush G.
January 8, 2025 at 4:08 PM
Reposted by Piyush G.
This is what I have added to my .bashrc file
alias untar="tar xvf"
alias untgz="tar xvzf"
alias untargz="tar xvzf"
alias unbz2="tar xvjf"
#Linux #Bash #bioinformatics
alias untar="tar xvf"
alias untgz="tar xvzf"
alias untargz="tar xvzf"
alias unbz2="tar xvjf"
#Linux #Bash #bioinformatics
December 30, 2024 at 12:41 AM
This is what I have added to my .bashrc file
alias untar="tar xvf"
alias untgz="tar xvzf"
alias untargz="tar xvzf"
alias unbz2="tar xvjf"
#Linux #Bash #bioinformatics
alias untar="tar xvf"
alias untgz="tar xvzf"
alias untargz="tar xvzf"
alias unbz2="tar xvjf"
#Linux #Bash #bioinformatics
Reposted by Piyush G.
Benchmarking AI Models for In Silico Gene Perturbation of Cells https://www.biorxiv.org/content/10.1101/2024.12.20.629581v1 🧬🖥️🧪
December 23, 2024 at 7:30 PM
Benchmarking AI Models for In Silico Gene Perturbation of Cells https://www.biorxiv.org/content/10.1101/2024.12.20.629581v1 🧬🖥️🧪
Reposted by Piyush G.
🎁 New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 🧬 🖥️
youtu.be/NGbZmlGLG5w
youtu.be/NGbZmlGLG5w
RNA-seq tutorial with DESeq2: Differential gene expression project
YouTube video by OMGenomics
youtu.be
December 17, 2024 at 11:17 PM
🎁 New RNA-Seq tutorial! Learn to run differential expression analysis with DESeq2, and create your own bioinformatics projects using public data and the Expression Atlas 🧬 🖥️
youtu.be/NGbZmlGLG5w
youtu.be/NGbZmlGLG5w
Reposted by Piyush G.
Put 👏🏼 the 👏🏼 sample 👏🏼 size 👏🏼 in 👏🏼 the 👏🏼 abstract 👏🏼
December 12, 2024 at 5:25 PM
Put 👏🏼 the 👏🏼 sample 👏🏼 size 👏🏼 in 👏🏼 the 👏🏼 abstract 👏🏼
Reposted by Piyush G.
Friends don't let friends make bad graphs repo has been updated!
Friends don't let friends use histogram for small sample sizes. Bin numbers affect the appearance of histograms, thus not robust to small (and modest sample sizes). They stabilize w/ large sample sizes.
github.com/cxli233/Frie...
Friends don't let friends use histogram for small sample sizes. Bin numbers affect the appearance of histograms, thus not robust to small (and modest sample sizes). They stabilize w/ large sample sizes.
github.com/cxli233/Frie...
December 10, 2024 at 4:30 PM
Friends don't let friends make bad graphs repo has been updated!
Friends don't let friends use histogram for small sample sizes. Bin numbers affect the appearance of histograms, thus not robust to small (and modest sample sizes). They stabilize w/ large sample sizes.
github.com/cxli233/Frie...
Friends don't let friends use histogram for small sample sizes. Bin numbers affect the appearance of histograms, thus not robust to small (and modest sample sizes). They stabilize w/ large sample sizes.
github.com/cxli233/Frie...
#Google just announced the Willow their new #quantumchips
Can we expect a future where we will be doing seconds (yes, seconds) of MD Simulations using such quantum chips. .
blog.google/technology/r...
#drugdiscovery #mdsimulation #willow #quantumchip
Can we expect a future where we will be doing seconds (yes, seconds) of MD Simulations using such quantum chips. .
blog.google/technology/r...
#drugdiscovery #mdsimulation #willow #quantumchip
Meet Willow, our state-of-the-art quantum chip
Our new quantum chip demonstrates error correction and performance that paves the way to a useful, large-scale quantum computer.
blog.google
December 10, 2024 at 6:40 AM
#Google just announced the Willow their new #quantumchips
Can we expect a future where we will be doing seconds (yes, seconds) of MD Simulations using such quantum chips. .
blog.google/technology/r...
#drugdiscovery #mdsimulation #willow #quantumchip
Can we expect a future where we will be doing seconds (yes, seconds) of MD Simulations using such quantum chips. .
blog.google/technology/r...
#drugdiscovery #mdsimulation #willow #quantumchip
Ok so this #deepvariant caller update from #google is BIG.
github.com/google/deepv...
- 1.6x time reduction (40% increase ??)
- Pangenome integration
- New model and improvements over previously model
Excited to try this new update 🧬💻
#bioinformatics #wgs #ngs #variantcalling
github.com/google/deepv...
- 1.6x time reduction (40% increase ??)
- Pangenome integration
- New model and improvements over previously model
Excited to try this new update 🧬💻
#bioinformatics #wgs #ngs #variantcalling
Release DeepVariant 1.8.0 · google/deepvariant
In this release:
Small model integration: Speed increased by ~1.7x (40% runtime reduction) for WGS, PacBio, and ONT by introduction of additional small model. The small model identifies easy-to-...
github.com
December 9, 2024 at 6:39 AM
Ok so this #deepvariant caller update from #google is BIG.
github.com/google/deepv...
- 1.6x time reduction (40% increase ??)
- Pangenome integration
- New model and improvements over previously model
Excited to try this new update 🧬💻
#bioinformatics #wgs #ngs #variantcalling
github.com/google/deepv...
- 1.6x time reduction (40% increase ??)
- Pangenome integration
- New model and improvements over previously model
Excited to try this new update 🧬💻
#bioinformatics #wgs #ngs #variantcalling
Reposted by Piyush G.
New in @theinnovation.bsky.social! Thirteen years of clusterProfiler.
This article provides a comprehensive review of the 13-year developmental trajectory of the research team in advancing #clusterProfiler. Read more
doi.org/10.1016/j.xi...
#bioinformatics #genomics #lifesciences
This article provides a comprehensive review of the 13-year developmental trajectory of the research team in advancing #clusterProfiler. Read more
doi.org/10.1016/j.xi...
#bioinformatics #genomics #lifesciences
December 8, 2024 at 5:06 AM
New in @theinnovation.bsky.social! Thirteen years of clusterProfiler.
This article provides a comprehensive review of the 13-year developmental trajectory of the research team in advancing #clusterProfiler. Read more
doi.org/10.1016/j.xi...
#bioinformatics #genomics #lifesciences
This article provides a comprehensive review of the 13-year developmental trajectory of the research team in advancing #clusterProfiler. Read more
doi.org/10.1016/j.xi...
#bioinformatics #genomics #lifesciences
Reposted by Piyush G.
When you check on your cell culture after the weekend
December 1, 2024 at 12:26 PM
When you check on your cell culture after the weekend
Has #Bioinformatics usage in #genomics increased Patient's survival rate in #cancer ? AT SCALE
Personalised Medicine is still #trending but I believe we will need more mass adoption with optimised cost to see it go mainstream. 🧬🖥
Personalised Medicine is still #trending but I believe we will need more mass adoption with optimised cost to see it go mainstream. 🧬🖥
November 27, 2024 at 8:04 PM
Has #Bioinformatics usage in #genomics increased Patient's survival rate in #cancer ? AT SCALE
Personalised Medicine is still #trending but I believe we will need more mass adoption with optimised cost to see it go mainstream. 🧬🖥
Personalised Medicine is still #trending but I believe we will need more mass adoption with optimised cost to see it go mainstream. 🧬🖥
This is a sad state of Cancer treatment in India, where we already are struggling with the cures. Main stream public speakers are peddling pseudo-science. Irony is the patient herself is Dr. & went through rounds of modern treatment & chemotherapy.
November 23, 2024 at 7:57 PM
This is a sad state of Cancer treatment in India, where we already are struggling with the cures. Main stream public speakers are peddling pseudo-science. Irony is the patient herself is Dr. & went through rounds of modern treatment & chemotherapy.
What if we can store that Megabytes of data (0101) in those Megabases (ATGC) ? And then use this to train ourselves like a RAG for LLM technique to get better at things 🤔💭
a man wearing glasses and a black turtleneck is holding his hands to his head .
Alt: a man wearing glasses and a black turtleneck is holding his hands to his head .
media.tenor.com
November 22, 2024 at 6:41 AM
What if we can store that Megabytes of data (0101) in those Megabases (ATGC) ? And then use this to train ourselves like a RAG for LLM technique to get better at things 🤔💭
Reposted by Piyush G.
TIL, logo for HOMER tool 🧬💻 is literally Homer Simpson🍩
November 20, 2024 at 9:42 AM
TIL, logo for HOMER tool 🧬💻 is literally Homer Simpson🍩
Hello grch38/hg19 users, have a good day ! 🧬🖥
November 19, 2024 at 6:02 AM
Hello grch38/hg19 users, have a good day ! 🧬🖥
Reposted by Piyush G.
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
docs.bsky.app
November 18, 2024 at 2:48 PM
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics
docs.bsky.app/docs/advance...
#AcademicSky #HigherEd #Altmetrics