Agnes Caruso
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agnescaruso.bsky.social
Agnes Caruso
@agnescaruso.bsky.social
Geneticist, product manager & photographer #humangenetics #moleculardx #womenshealth #socialmedia. Opinions stated are my own. https://www.linkedin.com/in/agnieszkacaruso/
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From the NOVA ProductTank meeting in 2018, our team built a winning bridge! It was some serious fun, don't be fooled by the Lego blocks. No matter what you building the process is the same. #NOVAProductTANK #ProductTank #NOVA #productdesign #productmanagement
Antisense Oligonucleotides or ASOs are another of the modern therapy options available to patients suffering from rare diseases.
Breakthrough Antisense Oligonucleotide Treatments Explained
Claire's story highlights her transformation from a child with spinal muscular atrophy to one able to walk and communicate, thanks to the breakthrough antisense oligonucleotide therapy, Spinraza. This therapy symbolizes hope for many genetic conditions, though challenges remain, including delivery difficulties, side effects, high costs, and the need for further research in efficacy and access.
geneiq.org
November 12, 2025 at 7:18 AM
Reposted by Agnes Caruso
The UNC Department of Biology is seeking a Director of Biology Teaching Labs, a key leadership role overseeing our undergraduate laboratory program. 1/n
Learn more and apply here: unc.peopleadmin.com/postings/308...
Director of Biology Teaching Labs
The Director of Biology Teaching Labs provides leadership and direction in the management of the Biology Department's undergraduate laboratories and will be responsible for the undergraduate laborator...
unc.peopleadmin.com
October 27, 2025 at 2:12 PM
Reposted by Agnes Caruso
AFGE late-night update to CDC layoff number

In total, 4,300 dedicated public servants are no longer serving at CDC. The effective reduction in workforce is approximately 33%.
October 15, 2025 at 3:06 AM
Reposted by Agnes Caruso
FC: Ask your elected officials to visit your lab and see what is going on and why it's important. This is the most important thing for getting Congresspeople on board. #ASHG25
October 14, 2025 at 9:00 PM
48th annual meeting is an amazing achievement!
Well deserved standing ovation for Francis Collins. This is his 48th annual meeting! 🤯 #ASHG25
October 15, 2025 at 2:31 AM
Talk to your reps if you are in US but also to you members of parliament in any other country. Politicians need to hear it from scientists. Advancements in healthcare are build on primary research successes.
@eshg.bsky.social
Francis Collins encouraging scientists to not only reach out to their reps about the importance of their research, but to use personal stories - not just stats and graphs

Science communication and advocacy going to be a theme this week - glad I'm here! #ASHG25
October 15, 2025 at 2:26 AM
Reposted by Agnes Caruso
For those interested in #Indigenous #Genomics and #ASHG25 in Boston, here are some interested posters/talks/events coming out of the Tsosie Lab, @nativebio.bsky.social, and @d4itdr.bsky.social. For those looking for Friday plans, attend our Ancillary Event, debuting a #Tribal #data repository!
October 14, 2025 at 2:29 PM
AAv therapies have been around for a while but the novel approaches position them to treat some very serious genetic diseases. They are not without problems but you can learn more from this article.
Understanding AAV Therapies: A Breakthrough for Genetic Diseases
Baby Josephine and her sister Evelyn both faced spinal muscular atrophy type 1. Traditional treatments failed, but Evelyn's participation in a clinical trial for the gene therapy Zolgensma transformed her life. Despite its $2.1 million cost and risks, early intervention with Zolgensma significantly improved outcomes for children diagnosed with SMA.
geneiq.org
October 14, 2025 at 2:53 AM
Reposted by Agnes Caruso
Congrats #Maldives 🇲🇻 for eliminating mother-to-child transmission of hep B!

The country is also maintaining
🏆 Elimination of mother-to-child transmission HIV
🏆 Elimination of mother-to-child transmission syphilis

This makes Maldives the first country in the world to achieve 'triple elimination'
October 13, 2025 at 10:02 AM
It will be interesting to watch if the end if vaccine mandates will happen.
#immunization
www.healio.com/news/pediatr...
Florida moves to end vaccine mandates
Florida Surgeon General Joseph Ladapo, MD, PhD, announced Wednesday that the state will work to “end all vaccine mandates,” including for children.“Every last one of them is wrong an...
www.healio.com
October 13, 2025 at 9:09 AM
Reposted by Agnes Caruso
📣Call for funded observerships is now open
We are awarding 50 young scientists up to 2K EUR to travel to one of the over 100 collaborative centres for knowledge exchange in the fields of CM & ID!

Learn more: ow.ly/zVUZ50WRNbA

#IDSky #clinmicro
September 9, 2025 at 11:21 AM
CRISPR-driven genome editing can be used to create treatments for rare diseases. In this post we look at how a treatment for sickle cell disease is changing lives of patients.
Revolutionizing Sickle Cell Treatment with CRISPR
Victoria Grey, diagnosed with sickle cell disease (SCD) at three months, defied a seven-year life expectancy, suffering for 34 years. Traditional treatments failed until she participated in a groundbreaking CRISPR trial, successfully reactivating healthy hemoglobin production. Victoria is now pain-free, showcasing the potential of genetic medicine to cure chronic conditions.
geneiq.org
September 2, 2025 at 9:00 AM
Next generation therapies are here and we can cure more diseases than we ever thought possible. Patients with rare genetic diseases, once incurable, can get a treatment that changes their life. That said these treatments come with some risks, and high price tags.
Beyond Pills and Surgery: The Therapeutic Revolution Happening Now
For over a century, traditional medicine offered pills and surgery, effectively managing many conditions. However, it often falls short for genetic diseases. The advent of precision therapies, such as CRISPR and AAV gene therapy, marks a revolutionary shift, curing root causes rather than managing symptoms, thus transforming patient outcomes.
geneiq.org
August 23, 2025 at 7:35 AM
Reposted by Agnes Caruso
youtu.be/dwgXtnaSoJQ?...
How many vaccine-preventable deaths are too many?
Beyond the Noise #77: A 'modest' number of deaths
YouTube video by MicrobeTV
youtu.be
August 11, 2025 at 10:08 AM
Have you ever had cafe romano? I finally made it is really refreshing.
August 11, 2025 at 3:04 AM
Reposted by Agnes Caruso
This is our satellite. Bought and paid for with taxpayer dollars, appropriated for this specific mission by the elected Congress. Those who would destroy it on purpose are our enemies.
Head of NASA Sean Duffy intends to destroy a satellite that collects key data on carbon dioxide and plant health, by causing it to burn up in the atmosphere. The U.S. Dept of Agriculture and private agriculture firms use the data to forecast crop yield, drought conditions and more.
Why a NASA satellite that scientists and farmers rely on may be destroyed on purpose
The Trump administration has asked NASA staffers to draw up plans to end at least two satellite missions that measure carbon dioxide in the atmosphere, according to current and former NASA employees.
www.npr.org
August 10, 2025 at 5:50 AM
Reposted by Agnes Caruso
🇬🇧 Full list of Costa Coffee outlet closures revealed www.standard.co.uk/business/cos...
Full list of Costa Coffee outlet closures revealed
Discover the full list of Costa Coffee shops closing across the UK as the brand signals high street concerns
www.standard.co.uk
August 9, 2025 at 3:00 AM
Reposted by Agnes Caruso
OMG.
45 years without the federal government ever using its §203 patent march-in rights under Bayh-Dole* . . . until now! When they can be used to bludgeon Harvard.

*Unless I have that wrong, @marklemley.bsky.social ? or other patent friends?

www.wsj.com/us-news/educ...
Trump Administration Threatens to Take Over Harvard’s Patents
The move is the latest escalation in the White House’s battle with the Ivy League school.
www.wsj.com
August 9, 2025 at 3:40 AM
Reposted by Agnes Caruso
Brazilian startup Karaja Biosciences is using bacteriophages to fight mastitis in dairy cows. This may cut antibiotic use and help tackle #AMR. A #OneHealth solution rooted in science and nature.

pesquisaparainovacao.fapesp.br/empresa_bras...
Empresa brasileira desenvolve alternativa sustentável a antibióticos para a pecuária
Startup utiliza bacteriófagos para prevenir mastite em vacas leiteiras e reduzir uso de medicamentos convencionais
pesquisaparainovacao.fapesp.br
August 4, 2025 at 9:23 PM
Reposted by Agnes Caruso
"One in three Aussie women are now migraine sufferers"
(ABC news App headline)

...is not this...

"It found one in three Australian women who had been diagnosed with migraine experienced at least one in the past three months"
(quite from the ABC article)

www.abc.net.au/news/2025-08...
One in three Aussie women are now migraine sufferers
A new survey has revealed the prevalence of migraines is far worse in Australian women than experts previously estimated.
www.abc.net.au
August 4, 2025 at 9:55 PM