Oren Kobiler
@orenkobiler.bsky.social
Ph.D. M.D. A virologist at Tel Aviv University
Pinned
Oren Kobiler
@orenkobiler.bsky.social
· Sep 16
Partial Inhibition of Viral Replication Machinery Enhances Recombination in Herpes Simplex Viruses
Herpes simplex viruses (HSV-1 and HSV-2) are widespread human pathogens, most commonly causing oral and genital lesions. These DNA viruses use recombination as a major driver of evolution. Intragenomi...
www.biorxiv.org
Maya’s work, showing anti herpetic drugs increase intra and inter species recombination is out on bioRxiv
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Oren Kobiler
Do you want to image RNA in living cells? Check out our new live-cell Click labeling approach. An amazing collaboration with the Meier Lab at UHH and the Wagenknecht Lab at KIT! doi.org/10.1002/anie...
Congratulations, especially to Doerte, Eileen, and Iven!
Thanks to DFG CRC1648
Congratulations, especially to Doerte, Eileen, and Iven!
Thanks to DFG CRC1648
Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters
The intracellular delivery of trans-cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron-demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro)....
doi.org
November 28, 2025 at 9:40 AM
Do you want to image RNA in living cells? Check out our new live-cell Click labeling approach. An amazing collaboration with the Meier Lab at UHH and the Wagenknecht Lab at KIT! doi.org/10.1002/anie...
Congratulations, especially to Doerte, Eileen, and Iven!
Thanks to DFG CRC1648
Congratulations, especially to Doerte, Eileen, and Iven!
Thanks to DFG CRC1648
Reposted by Oren Kobiler
“There were no cervical cancer cases diagnosed in women aged <25 years in 2021 – the first time that this has occurred in data going back to 1982. This remarkable achievement is almost certainly due to the impact of HPV vaccination.” From report.cervicalcancercontrol.org.au
#vaccinationsaveslives
#vaccinationsaveslives
November 26, 2025 at 10:53 AM
“There were no cervical cancer cases diagnosed in women aged <25 years in 2021 – the first time that this has occurred in data going back to 1982. This remarkable achievement is almost certainly due to the impact of HPV vaccination.” From report.cervicalcancercontrol.org.au
#vaccinationsaveslives
#vaccinationsaveslives
Eleven deaths from measles in Israel,
All in the ultra orthodox community.
Although the ministry of health is doing its best to convince these parents to vaccinate their children, the misinformation and mistrust are imbedded deeply in this population.
All in the ultra orthodox community.
Although the ministry of health is doing its best to convince these parents to vaccinate their children, the misinformation and mistrust are imbedded deeply in this population.
Tenth case, again unvaccinated under two years.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
The ninth victim of Measles in the current outbreak in Israel.
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
November 25, 2025 at 10:49 AM
Eleven deaths from measles in Israel,
All in the ultra orthodox community.
Although the ministry of health is doing its best to convince these parents to vaccinate their children, the misinformation and mistrust are imbedded deeply in this population.
All in the ultra orthodox community.
Although the ministry of health is doing its best to convince these parents to vaccinate their children, the misinformation and mistrust are imbedded deeply in this population.
Tenth case, again unvaccinated under two years.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
The ninth victim of Measles in the current outbreak in Israel.
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
November 24, 2025 at 8:28 AM
Tenth case, again unvaccinated under two years.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
Not only that these parents do not vaccinate their children, they also bring them to the hospital only when it is to late to save them.
The mistrust pandemic is killing these kids.
במסגרת פינתנו האהובה ״חיסונים עוזרים גם לדברים שלא ממש חשבנו שיעזרו״
הפעם חיסון הmRNA נגד קורונה המושמצים בילדים
ילדים עם אטופיק דרמטיטיס הראו הרבה פחות תחלואה אחרי חיסון הקורונה גם מזיהומים לא קשורים ומאלרגיות כולל אסתמה
www.annallergy.org/article/S108...
הפעם חיסון הmRNA נגד קורונה המושמצים בילדים
ילדים עם אטופיק דרמטיטיס הראו הרבה פחות תחלואה אחרי חיסון הקורונה גם מזיהומים לא קשורים ומאלרגיות כולל אסתמה
www.annallergy.org/article/S108...
COVID-19 VACCINATION IS ASSOCIATED WITH REDUCED COMPLICATIONS IN PEDIATRIC PATIENTS WITH ATOPIC DERMATITIS
Atopic dermatitis (AD) involves immune dysregulation and increases the risk of allergic
and infectious conditions, often preceding asthma and allergic rhinitis in the atopic
triad. This study evaluate...
www.annallergy.org
November 23, 2025 at 6:49 AM
במסגרת פינתנו האהובה ״חיסונים עוזרים גם לדברים שלא ממש חשבנו שיעזרו״
הפעם חיסון הmRNA נגד קורונה המושמצים בילדים
ילדים עם אטופיק דרמטיטיס הראו הרבה פחות תחלואה אחרי חיסון הקורונה גם מזיהומים לא קשורים ומאלרגיות כולל אסתמה
www.annallergy.org/article/S108...
הפעם חיסון הmRNA נגד קורונה המושמצים בילדים
ילדים עם אטופיק דרמטיטיס הראו הרבה פחות תחלואה אחרי חיסון הקורונה גם מזיהומים לא קשורים ומאלרגיות כולל אסתמה
www.annallergy.org/article/S108...
Reposted by Oren Kobiler
How awful. This is outright health disinformation, lying to the American people. Not only is there massive evidence showing no link between vaccines & autism, there’s not even a plausible mechanism based on what we’ve learned about the genetics of autism, some environmental exposures in pregnancy
HEADS UP: CDC website now officially asserts that vaccines may cause autism.“Studies supporting a link have been ignored by health authorities.” Also says the “vaccines do not cause autism” header remains b/c of an agreement with Cassidy.
November 20, 2025 at 3:18 AM
How awful. This is outright health disinformation, lying to the American people. Not only is there massive evidence showing no link between vaccines & autism, there’s not even a plausible mechanism based on what we’ve learned about the genetics of autism, some environmental exposures in pregnancy
Reposted by Oren Kobiler
The U.S. government is now inarguably spreading medical disinformation that is going to kill babies preferentially.
Period.
This is an INTOLERABLE. UNPRECEDENTED. DANGEROUS. ATTACK. ON ALL OF US.
Period.
This is an INTOLERABLE. UNPRECEDENTED. DANGEROUS. ATTACK. ON ALL OF US.
November 20, 2025 at 3:29 AM
The U.S. government is now inarguably spreading medical disinformation that is going to kill babies preferentially.
Period.
This is an INTOLERABLE. UNPRECEDENTED. DANGEROUS. ATTACK. ON ALL OF US.
Period.
This is an INTOLERABLE. UNPRECEDENTED. DANGEROUS. ATTACK. ON ALL OF US.
Reposted by Oren Kobiler
CDC has overhauled its website to assert that “the claim ‘vaccines do not cause autism’ is not an evidence-based claim”
November 20, 2025 at 2:26 AM
CDC has overhauled its website to assert that “the claim ‘vaccines do not cause autism’ is not an evidence-based claim”
Reposted by Oren Kobiler
I never tire of seeing the amazing success of HPV vaccination. We are seeing the elimination of a leading oncogenic virus pathogen in real time
(Source: GAVI)
www.gavi.org/vaccineswork...
(Source: GAVI)
www.gavi.org/vaccineswork...
November 18, 2025 at 3:03 PM
I never tire of seeing the amazing success of HPV vaccination. We are seeing the elimination of a leading oncogenic virus pathogen in real time
(Source: GAVI)
www.gavi.org/vaccineswork...
(Source: GAVI)
www.gavi.org/vaccineswork...
נגיף הEBV (מחלת הנשיקה) נקשר לאחרונה להתפתחות טרשת נפוצה ועכשיו גם לזאבת👇🏼
מתי יהיה חיסון?
מתי יהיה חיסון?
Epstein-Barr virus may drive autoimmunity in lupus by infecting and reprogramming memory B cells, according to a new #ScienceTranslationalMedicine analysis of patient-derived blood samples. https://scim.ag/49orb21
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus
Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells to promote pathogenic antinuclear T and B cell responses in lupus.
scim.ag
November 18, 2025 at 7:10 AM
נגיף הEBV (מחלת הנשיקה) נקשר לאחרונה להתפתחות טרשת נפוצה ועכשיו גם לזאבת👇🏼
מתי יהיה חיסון?
מתי יהיה חיסון?
ההבדל בן קפיטליזם לקפיטליזם חזירי
בשרשור עוד כמה גרפים שמדגימים את זה כולל זה
בשרשור עוד כמה גרפים שמדגימים את זה כולל זה
November 16, 2025 at 9:29 AM
ההבדל בן קפיטליזם לקפיטליזם חזירי
בשרשור עוד כמה גרפים שמדגימים את זה כולל זה
בשרשור עוד כמה גרפים שמדגימים את זה כולל זה
Reposted by Oren Kobiler
Not good at all
Ethiopia confirms outbreak of deadly Marburg virus
Africa CDC says at least nine cases have been detected of Ebola-like illness, which kills up to 80% of those infected
www.theguardian.com
November 16, 2025 at 8:21 AM
Not good at all
Reposted by Oren Kobiler
New work from Tahirov x Lim collaboration! @qixianghe.bsky.social from my lab contributed the cryo-EM structures for this work. We are excited to help explain how anti-HSV drugs work and to guide their future development.
www.science.org/doi/10.1126/...
@unmc.bsky.social @uwbiochem.bsky.social
www.science.org/doi/10.1126/...
@unmc.bsky.social @uwbiochem.bsky.social
Structural basis of herpesvirus helicase-primase inhibition by pritelivir and amenamevir
Structural studies of HSV-1 helicase-primase revealed how pritelivir and amenamevir bind and block its helicase activity.
www.science.org
November 10, 2025 at 12:14 AM
New work from Tahirov x Lim collaboration! @qixianghe.bsky.social from my lab contributed the cryo-EM structures for this work. We are excited to help explain how anti-HSV drugs work and to guide their future development.
www.science.org/doi/10.1126/...
@unmc.bsky.social @uwbiochem.bsky.social
www.science.org/doi/10.1126/...
@unmc.bsky.social @uwbiochem.bsky.social
The ninth victim of Measles in the current outbreak in Israel.
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
November 9, 2025 at 11:01 AM
The ninth victim of Measles in the current outbreak in Israel.
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
הוירוס הרבה יותר מסוכן לילדים מהחיסון, כמה לא מפתיע
Important study
Children & adolescents are "far more likely to experience rare but serious heart & inflammatory conditions after a COVID-19 infection than after being vaccinated–and the risks after infection lasted much longer"
Next post has link to study itself
1/3
www.gavi.org/vaccineswork...
Children & adolescents are "far more likely to experience rare but serious heart & inflammatory conditions after a COVID-19 infection than after being vaccinated–and the risks after infection lasted much longer"
Next post has link to study itself
1/3
www.gavi.org/vaccineswork...
COVID-19 infection poses higher, longer heart risks to children than vaccination
A comprehensive analysis of English health records finds higher risk of rare heart complications in children and adolescents who caught COVID-19 compared to those who received an mRNA-based COVID vacc...
www.gavi.org
November 7, 2025 at 6:51 AM
הוירוס הרבה יותר מסוכן לילדים מהחיסון, כמה לא מפתיע
בעקבות ראיון שהתקיים ביום שישי בכאן 11 וגרם למתנגדי החיסונים לצאת למתקפה ברשתות המקבילות.
מזכיר את הכללים הבאים:
א. אין שני צדדים לדיון על חיסונים
ב. לא מעלים לשידור מתנגד חיסונים (גם אם יש לו תארים ותפקיד) ובטח לא בתקופה של מגפת חצבת קטלנית
מזכיר את הכללים הבאים:
א. אין שני צדדים לדיון על חיסונים
ב. לא מעלים לשידור מתנגד חיסונים (גם אם יש לו תארים ותפקיד) ובטח לא בתקופה של מגפת חצבת קטלנית
October 28, 2025 at 5:51 AM
בעקבות ראיון שהתקיים ביום שישי בכאן 11 וגרם למתנגדי החיסונים לצאת למתקפה ברשתות המקבילות.
מזכיר את הכללים הבאים:
א. אין שני צדדים לדיון על חיסונים
ב. לא מעלים לשידור מתנגד חיסונים (גם אם יש לו תארים ותפקיד) ובטח לא בתקופה של מגפת חצבת קטלנית
מזכיר את הכללים הבאים:
א. אין שני צדדים לדיון על חיסונים
ב. לא מעלים לשידור מתנגד חיסונים (גם אם יש לו תארים ותפקיד) ובטח לא בתקופה של מגפת חצבת קטלנית
הסטודנטים כל שנה צעירים יותר
או שאני פשוט מזדקן?
או שאני פשוט מזדקן?
October 26, 2025 at 9:13 AM
הסטודנטים כל שנה צעירים יותר
או שאני פשוט מזדקן?
או שאני פשוט מזדקן?
Reposted by Oren Kobiler
This is the kind of wall I like!
October 24, 2025 at 8:46 PM
This is the kind of wall I like!
במסגרת הדברים הטובים שהחיסונים עושים בלי שהתכוונו
והפעם החיסון נגד שלבקת
מתגלים דברים שאנשים שלקחו אותו פחות חולים בהם לעומת אלה שלא קיבלו את החיסון, במנגנון לא לגמרי ברור
או שהתפרצויות של נגיף הגורם לשלבקת בתוך הגוף גורמות להרבה מחלות או שהחיסון מפעיל את מערכת החיסון בצורה שמונעת גם דברים אחרים
והפעם החיסון נגד שלבקת
מתגלים דברים שאנשים שלקחו אותו פחות חולים בהם לעומת אלה שלא קיבלו את החיסון, במנגנון לא לגמרי ברור
או שהתפרצויות של נגיף הגורם לשלבקת בתוך הגוף גורמות להרבה מחלות או שהחיסון מפעיל את מערכת החיסון בצורה שמונעת גם דברים אחרים
October 24, 2025 at 12:53 PM
במסגרת הדברים הטובים שהחיסונים עושים בלי שהתכוונו
והפעם החיסון נגד שלבקת
מתגלים דברים שאנשים שלקחו אותו פחות חולים בהם לעומת אלה שלא קיבלו את החיסון, במנגנון לא לגמרי ברור
או שהתפרצויות של נגיף הגורם לשלבקת בתוך הגוף גורמות להרבה מחלות או שהחיסון מפעיל את מערכת החיסון בצורה שמונעת גם דברים אחרים
והפעם החיסון נגד שלבקת
מתגלים דברים שאנשים שלקחו אותו פחות חולים בהם לעומת אלה שלא קיבלו את החיסון, במנגנון לא לגמרי ברור
או שהתפרצויות של נגיף הגורם לשלבקת בתוך הגוף גורמות להרבה מחלות או שהחיסון מפעיל את מערכת החיסון בצורה שמונעת גם דברים אחרים
במסגרת רצף הציוצים שמראים יתרונות של חיסונים גם לדברים שלא ממש חשבו שהם מיועדים להם👇🏼
Covid mRNA vaccine is enhancing anti cancer treatment
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival
3-year survival twice as high with mRNA vaccine in lung cancer patients receiving immunotherapy
www.medpagetoday.com
October 21, 2025 at 6:49 AM
במסגרת רצף הציוצים שמראים יתרונות של חיסונים גם לדברים שלא ממש חשבו שהם מיועדים להם👇🏼
Covid mRNA vaccine is enhancing anti cancer treatment
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival
3-year survival twice as high with mRNA vaccine in lung cancer patients receiving immunotherapy
www.medpagetoday.com
October 21, 2025 at 6:46 AM
Covid mRNA vaccine is enhancing anti cancer treatment
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Reposted by Oren Kobiler
Open Faculty position 🚨
Are you a microbiologist 🦠 ready to open your own lab? Come join us at Tel Aviv University.
en-med.m.tau.ac.il/FOM-position...
Are you a microbiologist 🦠 ready to open your own lab? Come join us at Tel Aviv University.
en-med.m.tau.ac.il/FOM-position...
Positions at the Gray Faculty of Medical & Health Sciences
Positions at the Gray Faculty of Medical & Health Sciences
en-med.m.tau.ac.il
October 16, 2025 at 5:58 AM
Open Faculty position 🚨
Are you a microbiologist 🦠 ready to open your own lab? Come join us at Tel Aviv University.
en-med.m.tau.ac.il/FOM-position...
Are you a microbiologist 🦠 ready to open your own lab? Come join us at Tel Aviv University.
en-med.m.tau.ac.il/FOM-position...
הבוקר זה כיף לשמוע את המסוקים טסים דרומה , לשם שינוי
October 13, 2025 at 3:19 AM
הבוקר זה כיף לשמוע את המסוקים טסים דרומה , לשם שינוי