Oren Kobiler
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orenkobiler.bsky.social
Oren Kobiler
@orenkobiler.bsky.social
970 followers 510 following 90 posts
Ph.D. M.D. A virologist at Tel Aviv University
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orenkobiler.bsky.social
Oren Kobiler @orenkobiler.bsky.social · Sep 16
Maya’s work, showing anti herpetic drugs increase intra and inter species recombination is out on bioRxiv

www.biorxiv.org/content/10.1...
Partial Inhibition of Viral Replication Machinery Enhances Recombination in Herpes Simplex Viruses
Herpes simplex viruses (HSV-1 and HSV-2) are widespread human pathogens, most commonly causing oral and genital lesions. These DNA viruses use recombination as a major driver of evolution. Intragenomi...
www.biorxiv.org
Reposted by Oren Kobiler
cijilim.bsky.social
New work from Tahirov x Lim collaboration! @qixianghe.bsky.social from my lab contributed the cryo-EM structures for this work. We are excited to help explain how anti-HSV drugs work and to guide their future development.
www.science.org/doi/10.1126/...
@unmc.bsky.social @uwbiochem.bsky.social
Structural basis of herpesvirus helicase-primase inhibition by pritelivir and amenamevir
Structural studies of HSV-1 helicase-primase revealed how pritelivir and amenamevir bind and block its helicase activity.
www.science.org
November 10, 2025 at 12:14 AM
orenkobiler.bsky.social
The ninth victim of Measles in the current outbreak in Israel.
This time a 7 year old with co-morbidities and one vaccine dose.
Emphasizing the importance that everyone will be vaccinated so we can protect the most vulnerable.
All cases before were unvaccinated under 2 years from complete health
November 9, 2025 at 11:01 AM
orenkobiler.bsky.social
הוירוס הרבה יותר מסוכן לילדים מהחיסון, כמה לא מפתיע
gavinyamey.bsky.social Prof Gavin Yamey @gavinyamey.bsky.social · 9d
Important study

Children & adolescents are "far more likely to experience rare but serious heart & inflammatory conditions after a COVID-19 infection than after being vaccinated–and the risks after infection lasted much longer"

Next post has link to study itself

1/3

www.gavi.org/vaccineswork...
COVID-19 infection poses higher, longer heart risks to children than vaccination
A comprehensive analysis of English health records finds higher risk of rare heart complications in children and adolescents who caught COVID-19 compared to those who received an mRNA-based COVID vacc...
www.gavi.org
November 7, 2025 at 6:51 AM
orenkobiler.bsky.social
בעקבות ראיון שהתקיים ביום שישי בכאן 11 וגרם למתנגדי החיסונים לצאת למתקפה ברשתות המקבילות.
מזכיר את הכללים הבאים:
א. אין שני צדדים לדיון על חיסונים
ב. לא מעלים לשידור מתנגד חיסונים (גם אם יש לו תארים ותפקיד) ובטח לא בתקופה של מגפת חצבת קטלנית
October 28, 2025 at 5:51 AM
orenkobiler.bsky.social
תיראו מופתעים
October 26, 2025 at 1:59 PM
orenkobiler.bsky.social
הסטודנטים כל שנה צעירים יותר
או שאני פשוט מזדקן?
October 26, 2025 at 9:13 AM
Reposted by Oren Kobiler
madhupai.bsky.social
This is the kind of wall I like!
Cartoon showing a wall of vaccines around a virus to protect kids
October 24, 2025 at 8:46 PM
Reposted by Oren Kobiler
johnrossmd.bsky.social
Flu vaccine this year shows average to above-average effectiveness #IDSky
Adjusted VE against influenza-associated outpatient visits and hospitalization was 50.4% and 49.7%, respectively, for any influenza virus, and 45.4% and 46.1%, respectively, for influenza A viruses. Adjusted VE against hospitalization with the predominant influenza subtype, A(H1N1)pdm09, was 41.6%. These interim estimates suggest that vaccination reduced medically attended influenza-associated illness by approximately one half in eight Southern Hemisphere countries. Health authorities should prioritize vaccination of all eligible persons ≥6 months to reduce incidence of influenza disease.
October 23, 2025 at 12:33 PM
orenkobiler.bsky.social
במסגרת הדברים הטובים שהחיסונים עושים בלי שהתכוונו
והפעם החיסון נגד שלבקת
מתגלים דברים שאנשים שלקחו אותו פחות חולים בהם לעומת אלה שלא קיבלו את החיסון, במנגנון לא לגמרי ברור
או שהתפרצויות של נגיף הגורם לשלבקת בתוך הגוף גורמות להרבה מחלות או שהחיסון מפעיל את מערכת החיסון בצורה שמונעת גם דברים אחרים
cbarbermd.bsky.social Carolyn Barber, MD @cbarbermd.bsky.social · 24d
💥The shingles vaccine might be one of the most underrated health moves after 50.💥

New large study(174K pts):
▪️ 50% lower risk of vascular dementia
▪️ 27% fewer blood clots
▪️ 25% lower risk of heart attack or stroke
▪️ 21% lower risk of dying early
#BlueSky #MedSky #NewsSky #SciSky 🧪 #NurseSky #IDSky
October 24, 2025 at 12:53 PM
orenkobiler.bsky.social
במסגרת רצף הציוצים שמראים יתרונות של חיסונים גם לדברים שלא ממש חשבו שהם מיועדים להם👇🏼
October 21, 2025 at 6:49 AM
orenkobiler.bsky.social
Covid mRNA vaccine is enhancing anti cancer treatment

Cancer Study Links COVID Shots to Longer Survival www.medpagetoday.com/meetingcover...
Cancer Study Links COVID Shots to Longer Survival
3-year survival twice as high with mRNA vaccine in lung cancer patients receiving immunotherapy
www.medpagetoday.com
October 21, 2025 at 6:46 AM
Reposted by Oren Kobiler
drdorsalomon.bsky.social
Open Faculty position 🚨
Are you a microbiologist 🦠 ready to open your own lab? Come join us at Tel Aviv University.
en-med.m.tau.ac.il/FOM-position...
Positions at the Gray Faculty of Medical & Health Sciences
Positions at the Gray Faculty of Medical & Health Sciences
en-med.m.tau.ac.il
October 16, 2025 at 5:58 AM
orenkobiler.bsky.social
הבוקר זה כיף לשמוע את המסוקים טסים דרומה , לשם שינוי
October 13, 2025 at 3:19 AM
orenkobiler.bsky.social
How I feel about Trump and the hostages deal

“Even a stopped clock is right twice a day״
Marie von Ebner-Eschenbach
October 12, 2025 at 6:30 AM
orenkobiler.bsky.social
לחכות לקבל את הreviews למאמר<<< לחכות שהם כבר יהיו בבית 🎗
October 9, 2025 at 7:18 AM
Reposted by Oren Kobiler
asherleeks.bsky.social
I gave a talk last year at TEDxNewEngland aimed at introducing the idea of viral sociality to a general audience, including implications for evolution & virology. Video now available online below.

#socialviruses #evosky #virosky 🧪
The social lives of viruses | Asher Leeks | TEDxNewEngland
YouTube video by TEDx Talks
www.youtube.com
October 7, 2025 at 10:38 PM
orenkobiler.bsky.social
October 7th

Two years ago and still we are not healing

Bring all the hostages home
End the f***ing war
October 7, 2025 at 2:57 PM
Reposted by Oren Kobiler
erankatz.com
דנה ברלב. שם, שם.
October 7, 2025 at 7:18 AM
orenkobiler.bsky.social
עוד הוכחה לקשר בין נגיפי הרפס ודמנציה.
החיסון נגד שלבקת לא רק מוריד את הסיכוי לחלות שלבקת (לא כדאי לנסות) אלא גם מוריד את הסיכון לפתח דמנציה

www.nature.com/articles/s41...
Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine
Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.
www.nature.com
October 6, 2025 at 2:45 PM
Reposted by Oren Kobiler
doritreiss.bsky.social
Six young children died, one facing amputation of limbs, all unvaccinated, all from measles.

Protect your children.
belaaz.com/news/11-mont...
11-Month-Old Charedi Baby Faces Amputation After Severe Measles Complications - Belaaz News
An 11-month-old infant from Beitar Illit, hospitalized at Hadassah Medical Center after contracting measles, is scheduled for surgery to amputate all four limbs due to necrosis, according to a Tuesday...
belaaz.com
October 4, 2025 at 4:55 PM
Reposted by Oren Kobiler
drruth.bsky.social
The HPV vaccine is doing what had been promised.
17 years after it became available, HPV infections decreased significantly in vaccinated people and unvaccinated people because of herd immunity. buff.ly/WvjQ1BS

h/t @boghuma.bsky.social

#medsky #pedsky 🛟🧪
Light blue background. Young woman with dark hair makes a sign of strength with her arm and she has a vaccine bandaid on her upper arm. It says "The HPV Vaccine Works!"
October 5, 2025 at 1:51 AM
orenkobiler.bsky.social
Another one this morning. A total of five (three in the last week). Just terrible 😢
orenkobiler.bsky.social Oren Kobiler @orenkobiler.bsky.social · Sep 24
Another baby had died in Israel from measles today, she is the fourth child in last few months. None were vaccinated. In this case she got sick before she had a chance to be vaccinated.
This is completely preventable, if we had vaccinated enough kids.
Vaccines work
September 25, 2025 at 10:11 AM
orenkobiler.bsky.social
Another baby had died in Israel from measles today, she is the fourth child in last few months. None were vaccinated. In this case she got sick before she had a chance to be vaccinated.
This is completely preventable, if we had vaccinated enough kids.
Vaccines work
September 24, 2025 at 8:20 PM
orenkobiler.bsky.social
Not all viruses are bad.
Viruses are effective gene delivery mechanisms.

www.bbc.com/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.com
September 24, 2025 at 5:03 PM
Reposted by Oren Kobiler
biorxiv-microbiol.bsky.social
Partial Inhibition of Viral Replication Machinery Enhances Recombination in Herpes Simplex Viruses https://www.biorxiv.org/content/10.1101/2025.09.15.676234v1
September 16, 2025 at 3:18 AM