First Choice Foods Ltd, based in Rupandehi, is set to expand its French fry exports from the US to the UK, Australia, and Japan by early 2026. Founded by Krishna Prasad Paudel, the company produces premium potato products under the Himalayan Crisp brand. To enhance production, it is collaborating with 35,000 farmers across 26 districts, providing training in potato cultivation and production techniques.

Millions of migrants toil in grueling conditions in the Middle East, where brutal heat contributes to an alarming increase in kidney failure.

USAID gone and Global Fund grants delayed, vulnerable groups at high risk of HIV, experts warn.

:Antimicrobial resistance in uropathogens is increasing globally, particularly in resource-limited settings such as Nepal, limiting treatment options.Objectives:This study aimed to evaluate the antimicrobial resistance patterns of uropathogens isolated from patients with urinary tract infections (UTIs) in a tertiary care hospital in central Nepal.Design:This study utilized a retrospective study design.Methods:We retrospectively observed medical records from August 2023 to February 2024 at Manmohan Memorial Teaching Hospital in Nepal, focusing on patients with significant bacterial growth in urine samples and antibiotic sensitivity analysis for resistance trends.Results:Escherichia coli (E. coli) (64.7%) and Klebsiella pneumoniae (K. pneumoniae) (15.0%) were the most common uropathogens. Both showed the highest resistance to amoxicillin (>95%), while E. coli demonstrated the lowest resistance to gentamicin (7.4%) and nitrofurantoin (12.2%). Klebsiella pneumoniae also showed low resistance to gentamicin (12.0%) but higher resistance to nitrofurantoin (64.0%).Conclusion:Empirical therapy, including nitrofurantoin and aminoglycosides, is a viable option for combating antimicrobial resistance in Nepal, necessitating region-specific surveillance and multicentre studies.