Reposted
Have you been waiting for a conference dedicated to Vector-Pathogen Interactions? Well you're in luck. Myself, Sarah Merkling, Flaminia Catteruccia, and Utpal Pal have organized the conference for you with an amazing lineup. Mark your calendars and share!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Vector-Pathogen Interactions: From Vector Biology to Innovative Control Strategies | Keystone Symposia
Join us at the Keystone Symposia on Vector-Pathogen Interactions: From Vector Biology to Innovative Control Strategies, February 2027, in Geneva, with field leaders!
www.keystonesymposia.org
December 8, 2025 at 9:47 PM
Have you been waiting for a conference dedicated to Vector-Pathogen Interactions? Well you're in luck. Myself, Sarah Merkling, Flaminia Catteruccia, and Utpal Pal have organized the conference for you with an amazing lineup. Mark your calendars and share!
www.keystonesymposia.org/conferences/...
www.keystonesymposia.org/conferences/...
Reposted
Pleased to share our recent work in collaboration with the
@perrimonlab.bsky.social in which we perform the first genome-wide CRISPR knockout screen in Anopheles to examine essential fitness genes and genes associated with clodronate liposome function
www.nature.com/articles/s41...
@perrimonlab.bsky.social in which we perform the first genome-wide CRISPR knockout screen in Anopheles to examine essential fitness genes and genes associated with clodronate liposome function
www.nature.com/articles/s41...
A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes
Nature Communications - Mosquitoes are major vectors for the transmission of many serious pathogens. This study uses genome-wide CRISPR screens in the mosquito, Anopheles gambiae, to reveal new...
www.nature.com
December 2, 2025 at 7:34 PM
Pleased to share our recent work in collaboration with the
@perrimonlab.bsky.social in which we perform the first genome-wide CRISPR knockout screen in Anopheles to examine essential fitness genes and genes associated with clodronate liposome function
www.nature.com/articles/s41...
@perrimonlab.bsky.social in which we perform the first genome-wide CRISPR knockout screen in Anopheles to examine essential fitness genes and genes associated with clodronate liposome function
www.nature.com/articles/s41...
Reposted
Cellular and molecular keys to entry: Mechanisms mediating Orthoflavivirus infection of the #mosquito midgut PLOSPathogens
Cellular and molecular keys to entry: Mechanisms mediating Orthoflavivirus infection of the #mosquito midgut
by Godfrey Nattoh, Philip M. Armstrong, Doug E. Brackney
dlvr.it
October 28, 2025 at 3:15 AM
Cellular and molecular keys to entry: Mechanisms mediating Orthoflavivirus infection of the #mosquito midgut PLOSPathogens
Reposted
🚨 New pub alert! Check out our latest one that showcases how chemical and genetic innovations can recreate complex host–symbiotic interactions in the absence of the symbiont.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
October 10, 2025 at 12:32 PM
🚨 New pub alert! Check out our latest one that showcases how chemical and genetic innovations can recreate complex host–symbiotic interactions in the absence of the symbiont.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted
Implications of successive blood feeding on #dengue virus inhibition by Wolbachia in Aedes aegypti mosquitoes
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes - Nature Communications
Dengue virus transmission by Ae. aegypti mosquitoes poses a significant public health threat, necessitating innovative control strategies. Here, the authors demonstrate that, while successive blood feeding increases earlier dengue virus dissemination, the inhibitory effects of Wolbachia remain strong, highlighting Wolbachia’s potential to disrupt dengue transmission under natural feeding conditions.
bit.ly
October 3, 2025 at 4:59 PM
Implications of successive blood feeding on #dengue virus inhibition by Wolbachia in Aedes aegypti mosquitoes
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
Reposted
The invasive form of Ae. #aegypti mosquito evolved within the Americas, after arriving from Africa ~320 ya. Our most recent paper is out @science.org. Years of work with collaborators all around led by J. Crawford! Great resource for the Vector Research community!.
www.science.org/content/arti...
www.science.org/content/arti...
How the yellow fever mosquito conquered the world
Aedes aegypti further adapted to life around humans when it arrived in the Americas, study of hundreds of mosquito genomes reveals
www.science.org
September 19, 2025 at 5:53 PM
The invasive form of Ae. #aegypti mosquito evolved within the Americas, after arriving from Africa ~320 ya. Our most recent paper is out @science.org. Years of work with collaborators all around led by J. Crawford! Great resource for the Vector Research community!.
www.science.org/content/arti...
www.science.org/content/arti...
Reposted
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Heterogeneity in inhibition of genetically diverse dengue virus strains by Wolbachia
The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...
www.biorxiv.org
September 19, 2025 at 7:23 PM
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Reposted
🚀 Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes - BMC Biology
Background Arthropod-borne viruses (arboviruses) such as dengue virus (DENV) and Zika virus (ZIKV) pose a significant threat to global health. Novel approaches to control the spread of arboviruses foc...
bmcbiol.biomedcentral.com
August 27, 2025 at 12:10 PM
🚀 Excited to share (with a little delay) my first first-author publication on #Vago genes in #mosquitoes! 🦟 🦠 Have a look to see how we questioned a mosquito immunity dogma and challenged the existing understanding of Vago-like genes as antiviral factors ⬇️
bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com/articles/10....
Reposted
Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)
🦟🦠 Check out our latest article in @natcomms.nature.com on the genetic basis of #dengue virus susceptibility in #mosquitoes! Collaborative work brillantly led by @merklinglab.bsky.social and @elodiecouderc.bsky.social @pasteur.fr and primarily supported by @agencerecherche.bsky.social rdcu.be/eBbg7
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants
Nature Communications - Genetic factors affecting Aedes aegypti susceptibility to dengue virus infection aren’t well studied. Here the authors show that a cytochrome P450 gene, typically...
rdcu.be
August 18, 2025 at 12:05 PM
Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)
Reposted
Thrilled to be a part of this study on Wolbachia and multiple blood feeding. Now published!
rdcu.be/eyqaG
rdcu.be/eyqaG
Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes
Nature Communications - Dengue virus transmission by Ae. aegypti mosquitoes poses a significant public health threat, necessitating innovative control strategies. Here, the authors demonstrate...
rdcu.be
July 30, 2025 at 2:21 AM
Thrilled to be a part of this study on Wolbachia and multiple blood feeding. Now published!
rdcu.be/eyqaG
rdcu.be/eyqaG
Reposted
Excellent new study from the Catteruccia lab, co-led by Alexandra Probst and Douglas Paton www.nature.com/articles/s41...
In vivo screen of Plasmodium targets for mosquito-based malaria control - Nature
An in vivo screen of small-molecule compounds to inhibit the mosquito-stage development of Plasmodium identified hits that can be incorporated into bed nets and led to effective parasite killing in th...
www.nature.com
May 22, 2025 at 1:55 PM
Excellent new study from the Catteruccia lab, co-led by Alexandra Probst and Douglas Paton www.nature.com/articles/s41...
Reposted
Despite all the shit going on, we have to celebrate our victories. New publication with @entomososwin.bsky.social and @vectorimmunity.bsky.social showing that hemocytes play a central role in disseminating flaviviruses to secondary tissues potentially functioning as a Trojan Horse(TBD)
rdcu.be/euj4g
rdcu.be/euj4g
Mosquito immune cells enhance dengue and Zika virus infection in Aedes aegypti
Nature Communications - Infection of mosquito immune cells by dengue and Zika virus enhances the spread of virus infection to mosquito tissues, such as the salivary glands, to promote virus...
rdcu.be
July 1, 2025 at 3:02 PM
Despite all the shit going on, we have to celebrate our victories. New publication with @entomososwin.bsky.social and @vectorimmunity.bsky.social showing that hemocytes play a central role in disseminating flaviviruses to secondary tissues potentially functioning as a Trojan Horse(TBD)
rdcu.be/euj4g
rdcu.be/euj4g
Reposted
Come and join the @mossi-lab.bsky.social group! We have a postdoc position available on Wolbachia and Anopheles interactions.
app.vacancy-filler.co.uk/salescrm/Car...
app.vacancy-filler.co.uk/salescrm/Car...
Post Doctoral Research Associate in Wolbachia Biology | Liverpool School of Tropical Medicine
Ready to make a difference in vector biology research? We are looking for a dedicated and enthusiastic researcher to join an exciting BBSRC-funded project exploring the fascinating interactions betwee...
app.vacancy-filler.co.uk
June 18, 2025 at 3:34 PM
Come and join the @mossi-lab.bsky.social group! We have a postdoc position available on Wolbachia and Anopheles interactions.
app.vacancy-filler.co.uk/salescrm/Car...
app.vacancy-filler.co.uk/salescrm/Car...
Reposted
Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
🔗 All positions: ki.se/en/about-ki/...
🔗 All positions: ki.se/en/about-ki/...
June 25, 2025 at 10:01 AM
Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
🔗 All positions: ki.se/en/about-ki/...
🔗 All positions: ki.se/en/about-ki/...
Reposted
🎉 Our study is now published in Cell Genomics ! Thank to our reviewers for helping us further improve our work, and congratulations to @tompvial.bsky.social who lead this project and the entire team that made it possible ! www.cell.com/cell-genomic...
June 26, 2025 at 10:20 AM
🎉 Our study is now published in Cell Genomics ! Thank to our reviewers for helping us further improve our work, and congratulations to @tompvial.bsky.social who lead this project and the entire team that made it possible ! www.cell.com/cell-genomic...
Reposted
Next up Godfrey Nattoh from the Agricultural research station presenting on early dengue infection in the mosquito vector
February 21, 2025 at 6:56 PM
Next up Godfrey Nattoh from the Agricultural research station presenting on early dengue infection in the mosquito vector
Reposted
📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
May 15, 2025 at 8:16 AM
📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert
Reposted
Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Hsc70-4: An unanticipated mediator of dsRNA internalization in Drosophila
Hsc70-4 localizes to the cell surface of Drosophila cells, binds to exogenous dsRNA, and mediates its internalization.
www.science.org
May 20, 2025 at 2:47 PM
Stop for a second and try to imagine this: a heat shock protein relocalizes to the cell surface and mediates dsRNA binding and internalization!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Intrigued? Read our newly minted paper in Science Advances www.science.org/doi/10.1126/...
Congrats to all the authors and thanks to reviewers and editor!
Reposted
New paper from the lab:
Bianca Morejon defines the regulatory protease network that governs #mosquito #immunity
www.pnas.org/doi/10.1073/...
Bianca Morejon defines the regulatory protease network that governs #mosquito #immunity
www.pnas.org/doi/10.1073/...
The expanded immunoregulatory protease network in mosquitoes is governed by gene coexpression | PNAS
Serine protease cascades regulate key innate immune responses. Their activation cleaves
a series of inactive protease zymogens, which then activate...
www.pnas.org
May 2, 2025 at 3:02 PM
New paper from the lab:
Bianca Morejon defines the regulatory protease network that governs #mosquito #immunity
www.pnas.org/doi/10.1073/...
Bianca Morejon defines the regulatory protease network that governs #mosquito #immunity
www.pnas.org/doi/10.1073/...
Reposted
📢New preprint! We studied the impact of successive feeding on inhibition of dengue virus by Wolbachia
Key finding: mosquito feeding behavior matters, but Wolbachia remains effective🦟🦠
Study led by @entomososwin.bsky.social and Mallery Breban
www.biorxiv.org/content/10.1...
Key finding: mosquito feeding behavior matters, but Wolbachia remains effective🦟🦠
Study led by @entomososwin.bsky.social and Mallery Breban
www.biorxiv.org/content/10.1...
Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes
Dengue virus (DENV) is a mosquito-borne virus that poses a continued and increasing threat to public health. A promising strategy to mitigate the burden of DENV is introgression of the virus-inhibitin...
www.biorxiv.org
February 7, 2025 at 6:40 PM
📢New preprint! We studied the impact of successive feeding on inhibition of dengue virus by Wolbachia
Key finding: mosquito feeding behavior matters, but Wolbachia remains effective🦟🦠
Study led by @entomososwin.bsky.social and Mallery Breban
www.biorxiv.org/content/10.1...
Key finding: mosquito feeding behavior matters, but Wolbachia remains effective🦟🦠
Study led by @entomososwin.bsky.social and Mallery Breban
www.biorxiv.org/content/10.1...
Reposted
Happy to share our work exploring the genetic basis of dengue susceptibility in Aedes aegypti and revealing the antiviral role of a cytochrome P450. www.biorxiv.org/content/10.1...
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 variants
The mosquito Aedes aegypti is the primary vector for dengue virus (DENV), which infects millions of people annually. Variability in DENV susceptibility among wild Ae. aegypti populations is governed b...
www.biorxiv.org
February 28, 2025 at 12:17 PM
Happy to share our work exploring the genetic basis of dengue susceptibility in Aedes aegypti and revealing the antiviral role of a cytochrome P450. www.biorxiv.org/content/10.1...
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
It had been a long and wild ride that started back when I was a postdoc within @lambrechtslab.bsky.social ! A thread ⬇️
Reposted
I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research.
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1...
1/n
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1...
1/n
March 5, 2025 at 5:54 PM
I am thrilled to present the Mosquito Cell Atlas! We analyzed 367K nuclei from 19 tissues in male & female mosquitoes, creating a comprehensive resource for vector biology & infectious disease research.
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1...
1/n
Plus we made some surprising discoveries! 🦟🧵
biorxiv.org/content/10.1...
1/n