Nucleic Acids Research
@narjournal.bsky.social
Nucleic Acids Research (NAR), from Oxford University Press, publishes the results of leading-edge research into physical, chemical, biochemical and biological aspects of nucleic acids and proteins involved in nucleic acid metabolism and/or interactions
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Hello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!
Reposted by Nucleic Acids Research
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences
Abstract. Deciphering the functional effects of genetic variants, especially those inherited together on the same haplotype, remains a major challenge in h
doi.org
November 25, 2025 at 9:25 AM
🚨 Out in NAR @narjournal.bsky.social!
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
Introducing HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences.
📄 Paper: doi.org/10.1093/nar/...
💻 DB: bcglab.cibio.unitn.it/hapscoredb
#Bioinformatics #Genomics #ProteinLanguageModels #CompBio
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
November 25, 2025 at 5:10 PM
⭐ NAR Breakthrough! ⭐
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
🦠 New study shows phage X1 hijacks Yersinia's enterocolitica flagellum to inject its DNA directly into the cytosol. Yersinia, though, strikes back!
🦠 A fascinating look at the #dualrole of #flagella in #viralentry and #bacterialimmunity.
🧬 Read more: doi.org/10.1093/nar/...
⭐ NAR Breakthrough! ⭐
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
November 24, 2025 at 6:16 PM
⭐ NAR Breakthrough! ⭐
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
🔬 New study reveals how the Retron-Eco7 system helps bacteria sense and fight phage attacks, identifying a clever immune-sensing mechanism in the bacteria–phage arms race.
🧬 Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Microbiology #PhageBiology #BacterialDefense
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
November 21, 2025 at 6:18 PM
⭐ NAR Breakthrough! ⭐
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
🔬 New study by Betancurt et al. uses #PacBio single-molecule sequencing to build a long-read fidelity assay that reveals how different #DNApolymerase families make distinct errors.
🧬 Read more: doi.org/10.1093/nar/...
@nebiolabs.bsky.social @pasteur.fr
#NARBreakthrough
⭐ NAR Breakthrough! ⭐
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
November 20, 2025 at 6:01 PM
⭐ NAR Breakthrough! ⭐
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
A community-driven collection uniting 52 phages, 74 Klebsiella isolates, and extensive genomic + phenotypic data — all freely available at klebphacol.org.
🧬 Learn more: doi.org/10.1093/nar/...
@fnobrega.bsky.social @danielarothschild.bsky.social #antimicrobialresistance
📣 Authors wanted! Submit to NARMME's Special Collection on Repeat Expansion Diseases by Jan 2026🧬
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
October 30, 2025 at 10:28 AM
📣 Authors wanted! Submit to NARMME's Special Collection on Repeat Expansion Diseases by Jan 2026🧬
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🔍Find out more: academic.oup.com/narmolmed/pa...
👉Submit: mc.manuscriptcentral.com/narmme
#CallForPapers #Genomics #RareDiseases #NARMME
🧬 New in NARGAB: A fast, scalable CHT method identifies genomic regions with shared effects across traits. Applied to psychiatric pleiotropy and cucumber virus resistance.
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
October 16, 2025 at 3:45 PM
🧬 New in NARGAB: A fast, scalable CHT method identifies genomic regions with shared effects across traits. Applied to psychiatric pleiotropy and cucumber virus resistance.
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
Read: doi.org/10.1093/narg...
#CHT #MultiTraitAnalysis #PsychiatricGenetics #PlantGenomics
🧬 New in NARMME: RNA splicing tweaks rescue tau toxicity in C. elegans. Modifying tri-snRNP proteins rescues tau-induced deficits in transgenic C. elegans, restoring behaviour, neurodegeneration and extending lifespan.
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
October 16, 2025 at 3:41 PM
🧬 New in NARMME: RNA splicing tweaks rescue tau toxicity in C. elegans. Modifying tri-snRNP proteins rescues tau-induced deficits in transgenic C. elegans, restoring behaviour, neurodegeneration and extending lifespan.
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
Read: doi.org/10.1093/narm...
#Alzheimers #RNAsplicing #Neurodegeneration
⭐ NAR Breakthrough! ⭐
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
October 15, 2025 at 1:49 PM
⭐ NAR Breakthrough! ⭐
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
🔬 How do #kinetochores rebuild each #cellcycle?
A new study reveals the order of assembly, hidden interdependencies, and a new regulatory mechanism.
🧬 Read more: academic.oup.com/nar/article/... @suebiggins.bsky.social @fredhutch.org
#NARbreakthrough #ChromosomeSegregation
Five years ago, Dr. Doudna @jenniferdoudna.bsky.social and Dr. Charpentier won the #NobelPrize for #CRISPR/Cas9, revolutionizing gene editing and science as we know it. 🎉🎉Celebrate this milestone with our #specialcollections academic.oup.com/nar/pages/cr... and academic.oup.com/nar/pages/cr...
October 7, 2025 at 5:48 AM
Five years ago, Dr. Doudna @jenniferdoudna.bsky.social and Dr. Charpentier won the #NobelPrize for #CRISPR/Cas9, revolutionizing gene editing and science as we know it. 🎉🎉Celebrate this milestone with our #specialcollections academic.oup.com/nar/pages/cr... and academic.oup.com/nar/pages/cr...
⭐ NAR Breakthrough! ⭐
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
Disrupted transcriptional networks regulated by CHD1L during neurodevelopment underlie the mirrored neuroanatomical and growth phenotypes of the 1q21.1 copy number variant
Abstract. Distal 1q21.1 deletions and duplications are associated with variable phenotypes including autism, head circumference and height defects. To eluc
doi.org
September 24, 2025 at 5:34 PM
⭐ NAR Breakthrough! ⭐
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
New research highlights CHD1L in the chromosome 1q21.1 region—linked to #autism, head size & growth.
🧠 It controls #DNApackaging & genes for #braindevelopment, #cellfate & #connectivity.
Read more: doi.org/10.1093/nar/...
#NARBreakthrough #Neuroscience @igbmc.bsky.social
🧬 New in NARGAB: authors compared human exome sequencing kits, showing how design differences impact capture efficiency and downstream analysis. Useful insights for choosing the right kit!
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
September 22, 2025 at 2:19 PM
🧬 New in NARGAB: authors compared human exome sequencing kits, showing how design differences impact capture efficiency and downstream analysis. Useful insights for choosing the right kit!
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
📖 Read: doi.org/10.1093/narg...
#ExomeSequencing #Genomics #Bioinformatics #NARGAB
🧬New in NARGAB: a composite hypothesis testing (CHT) method to find genetic regions affecting multiple traits is described which is efficient, scalable and applied to psychiatric disorders and viral resistance in cucumber.
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
September 22, 2025 at 2:16 PM
🧬New in NARGAB: a composite hypothesis testing (CHT) method to find genetic regions affecting multiple traits is described which is efficient, scalable and applied to psychiatric disorders and viral resistance in cucumber.
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
Read here: doi.org/10.1093/narg...
#Genomics #CHT #Bioinformatics #NARGAB
🤰 New research in NARMME reveals that uterine glands, not just eggs, are sensitive to maternal aging. 🧬 FOXC1 marks early dysfunction, reshaping how we understand fertility decline.
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
September 19, 2025 at 5:04 PM
🤰 New research in NARMME reveals that uterine glands, not just eggs, are sensitive to maternal aging. 🧬 FOXC1 marks early dysfunction, reshaping how we understand fertility decline.
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
📖 Read more: lnkd.in/eahrVbMt
#FertilityResearch #FOXC1 #ReproductiveScience #NARMME #OpenAccessPublication
💡 New in NARMME: TRL1 enzyme from Candida glabrata changes shape to control RNA repair, vital for fungal survival. Its absence in humans makes it a promising antifungal drug target.
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
September 18, 2025 at 4:56 PM
💡 New in NARMME: TRL1 enzyme from Candida glabrata changes shape to control RNA repair, vital for fungal survival. Its absence in humans makes it a promising antifungal drug target.
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
📖 Read more: doi.org/10.1093/narm...
#TRL1 #RNARepair #AntifungalResearch #DrugDiscovery #NARMME #OpenAccess
🔬 New study in NARMME explores how azvudine (FNC) targets HIV-1 RT & SARS-CoV-2 RdRp🧬
📖 doi.org/10.1093/narm...
#Azvudine #AntiviralAgents #HIVResearch #SARSCoV2 #NARMolecularMedicine #OpenAccessPublication
📖 doi.org/10.1093/narm...
#Azvudine #AntiviralAgents #HIVResearch #SARSCoV2 #NARMolecularMedicine #OpenAccessPublication
September 18, 2025 at 4:47 PM
🔬 New study in NARMME explores how azvudine (FNC) targets HIV-1 RT & SARS-CoV-2 RdRp🧬
📖 doi.org/10.1093/narm...
#Azvudine #AntiviralAgents #HIVResearch #SARSCoV2 #NARMolecularMedicine #OpenAccessPublication
📖 doi.org/10.1093/narm...
#Azvudine #AntiviralAgents #HIVResearch #SARSCoV2 #NARMolecularMedicine #OpenAccessPublication
💡A new RNAi strategy described in NARMME embeds miR-based shRNAs into a gamma-retroviral intron, enabling gene knockdown and protein coexpression with high viral titers.
📖 doi.org/10.1093/narm...
#RNAi #GeneTherapy #RetroviralVectors #MolecularBiology #NARMME #OpenAccessPublication
📖 doi.org/10.1093/narm...
#RNAi #GeneTherapy #RetroviralVectors #MolecularBiology #NARMME #OpenAccessPublication
September 15, 2025 at 1:33 PM
💡A new RNAi strategy described in NARMME embeds miR-based shRNAs into a gamma-retroviral intron, enabling gene knockdown and protein coexpression with high viral titers.
📖 doi.org/10.1093/narm...
#RNAi #GeneTherapy #RetroviralVectors #MolecularBiology #NARMME #OpenAccessPublication
📖 doi.org/10.1093/narm...
#RNAi #GeneTherapy #RetroviralVectors #MolecularBiology #NARMME #OpenAccessPublication
🧬 A new review in NARMME explores how chromatin preserves cell identity and how its breakdown may drive diseases like neurodegeneration and cancer.
📖 doi.org/10.1093/narm...
#Epigenetics #Chromatin #CellBiology #Genomics #Neuroscience #MolecularBiology #OpenAccess #NARMolecularMedicine
📖 doi.org/10.1093/narm...
#Epigenetics #Chromatin #CellBiology #Genomics #Neuroscience #MolecularBiology #OpenAccess #NARMolecularMedicine
September 15, 2025 at 1:11 PM
🧬 A new review in NARMME explores how chromatin preserves cell identity and how its breakdown may drive diseases like neurodegeneration and cancer.
📖 doi.org/10.1093/narm...
#Epigenetics #Chromatin #CellBiology #Genomics #Neuroscience #MolecularBiology #OpenAccess #NARMolecularMedicine
📖 doi.org/10.1093/narm...
#Epigenetics #Chromatin #CellBiology #Genomics #Neuroscience #MolecularBiology #OpenAccess #NARMolecularMedicine
🐟 New in NARMME: malat1 in zebrafish triggers signaling for retinal repair guided by Notch, Wnt & TGF-β pathways. In mammals, TGF-β blocks regeneration revealing a key difference in healing potential.
🔗 doi.org/10.1093/narm...
#Zebrafish #RetinaRepair #Malat1 #MolecularBiology #NARMME #OpenAccess
🔗 doi.org/10.1093/narm...
#Zebrafish #RetinaRepair #Malat1 #MolecularBiology #NARMME #OpenAccess
September 12, 2025 at 11:31 AM
🐟 New in NARMME: malat1 in zebrafish triggers signaling for retinal repair guided by Notch, Wnt & TGF-β pathways. In mammals, TGF-β blocks regeneration revealing a key difference in healing potential.
🔗 doi.org/10.1093/narm...
#Zebrafish #RetinaRepair #Malat1 #MolecularBiology #NARMME #OpenAccess
🔗 doi.org/10.1093/narm...
#Zebrafish #RetinaRepair #Malat1 #MolecularBiology #NARMME #OpenAccess
🦟 New in NARMME: for the first time, microRNA in tsetse fly saliva carrying Trypanosoma brucei were profiled. Infected flies carry less diverse microRNAs, hinting roles in how the disease spreads.
🔗 doi.org/10.1093/narm...
#SleepingSickness #TsetseFly #MicroRNA #Trypanosomes #NARMME #OpenAccess
🔗 doi.org/10.1093/narm...
#SleepingSickness #TsetseFly #MicroRNA #Trypanosomes #NARMME #OpenAccess
September 12, 2025 at 11:26 AM
🦟 New in NARMME: for the first time, microRNA in tsetse fly saliva carrying Trypanosoma brucei were profiled. Infected flies carry less diverse microRNAs, hinting roles in how the disease spreads.
🔗 doi.org/10.1093/narm...
#SleepingSickness #TsetseFly #MicroRNA #Trypanosomes #NARMME #OpenAccess
🔗 doi.org/10.1093/narm...
#SleepingSickness #TsetseFly #MicroRNA #Trypanosomes #NARMME #OpenAccess
⭐ #NARBreakthrough in #RNAengineering!⭐
University of Utah @utah.edu chemists show that a single dye can emit two colors with engineered #Broccoli #aptamers (Golden = yellow, Red = red).
They built the first ratiometric biosensor to track #glycine dynamics!
Read more 👉 doi.org/10.1093/nar/...
University of Utah @utah.edu chemists show that a single dye can emit two colors with engineered #Broccoli #aptamers (Golden = yellow, Red = red).
They built the first ratiometric biosensor to track #glycine dynamics!
Read more 👉 doi.org/10.1093/nar/...
September 11, 2025 at 2:42 PM
⭐ #NARBreakthrough in #RNAengineering!⭐
University of Utah @utah.edu chemists show that a single dye can emit two colors with engineered #Broccoli #aptamers (Golden = yellow, Red = red).
They built the first ratiometric biosensor to track #glycine dynamics!
Read more 👉 doi.org/10.1093/nar/...
University of Utah @utah.edu chemists show that a single dye can emit two colors with engineered #Broccoli #aptamers (Golden = yellow, Red = red).
They built the first ratiometric biosensor to track #glycine dynamics!
Read more 👉 doi.org/10.1093/nar/...
🌟 Discover NARGAB Editor's Choice articles, hand-picked by our Editor-in-Chief for their quality and impact.
👉 All articles are free to read and download, explore the full collection now!
🔗 academic.oup.com/nargab/pages...
#NARGenomicsandBioinformatics #EditorsChoice #OpenAccess
👉 All articles are free to read and download, explore the full collection now!
🔗 academic.oup.com/nargab/pages...
#NARGenomicsandBioinformatics #EditorsChoice #OpenAccess
September 9, 2025 at 1:57 PM
🌟 Discover NARGAB Editor's Choice articles, hand-picked by our Editor-in-Chief for their quality and impact.
👉 All articles are free to read and download, explore the full collection now!
🔗 academic.oup.com/nargab/pages...
#NARGenomicsandBioinformatics #EditorsChoice #OpenAccess
👉 All articles are free to read and download, explore the full collection now!
🔗 academic.oup.com/nargab/pages...
#NARGenomicsandBioinformatics #EditorsChoice #OpenAccess
Reposted by Nucleic Acids Research
@narjournal.bsky.social invites you to join the 2026 Early Career Investigator Advisory Board cohort!
You can collaborate with Executive Editors, influence the future of science, and elevate your career. Apply now or tag a colleague who might be interested: oxford.ly/47js8Ye
You can collaborate with Executive Editors, influence the future of science, and elevate your career. Apply now or tag a colleague who might be interested: oxford.ly/47js8Ye
Join Early Career Investigator Advisory Board
Nucleic Acids Research (NAR) warmly welcomes you to join us in shaping the future of our research community. We recognize the vital role that NAR can play in nu
oxford.ly
August 29, 2025 at 12:30 PM
@narjournal.bsky.social invites you to join the 2026 Early Career Investigator Advisory Board cohort!
You can collaborate with Executive Editors, influence the future of science, and elevate your career. Apply now or tag a colleague who might be interested: oxford.ly/47js8Ye
You can collaborate with Executive Editors, influence the future of science, and elevate your career. Apply now or tag a colleague who might be interested: oxford.ly/47js8Ye
⭐NAR Breakthrough!⭐
🧬 New study shows Prp22 has a dual role in #splicing—an ATP-independent function that promotes #exonligation by stabilizing Slu7, and an ATP-dependent role that drives Slu7 dissociation + #mRNArelease.
📖 ttps://doi.org/10.1093/nar/gkaf823
#NARBreakthrough #RNA #RNAHelicase
🧬 New study shows Prp22 has a dual role in #splicing—an ATP-independent function that promotes #exonligation by stabilizing Slu7, and an ATP-dependent role that drives Slu7 dissociation + #mRNArelease.
📖 ttps://doi.org/10.1093/nar/gkaf823
#NARBreakthrough #RNA #RNAHelicase
August 29, 2025 at 3:09 PM
⭐NAR Breakthrough!⭐
🧬 New study shows Prp22 has a dual role in #splicing—an ATP-independent function that promotes #exonligation by stabilizing Slu7, and an ATP-dependent role that drives Slu7 dissociation + #mRNArelease.
📖 ttps://doi.org/10.1093/nar/gkaf823
#NARBreakthrough #RNA #RNAHelicase
🧬 New study shows Prp22 has a dual role in #splicing—an ATP-independent function that promotes #exonligation by stabilizing Slu7, and an ATP-dependent role that drives Slu7 dissociation + #mRNArelease.
📖 ttps://doi.org/10.1093/nar/gkaf823
#NARBreakthrough #RNA #RNAHelicase
⭐NAR Breakthrough!⭐
🧬 New study shows that small activating RNAs can boost MBNL1 expression in #myotonicdystrophy cells, restoring splicing balance. This highlights #RNAactivation (RNAa) as a promising #therapeutic strategy for this #raredisease.
📖 doi.org/10.1093/nar/...
#NARBreakthrough
🧬 New study shows that small activating RNAs can boost MBNL1 expression in #myotonicdystrophy cells, restoring splicing balance. This highlights #RNAactivation (RNAa) as a promising #therapeutic strategy for this #raredisease.
📖 doi.org/10.1093/nar/...
#NARBreakthrough
Promoter-targeted small RNA duplexes increase MBNL1 transcription and mitigate myotonic dystrophy-associated spliceopathy
Abstract. Functional depletion of Muscleblind-like (MBNL) proteins is a key trigger of myotonic dystrophy (DM)-associated alternative splicing (AltS) defec
doi.org
August 20, 2025 at 3:18 PM
⭐NAR Breakthrough!⭐
🧬 New study shows that small activating RNAs can boost MBNL1 expression in #myotonicdystrophy cells, restoring splicing balance. This highlights #RNAactivation (RNAa) as a promising #therapeutic strategy for this #raredisease.
📖 doi.org/10.1093/nar/...
#NARBreakthrough
🧬 New study shows that small activating RNAs can boost MBNL1 expression in #myotonicdystrophy cells, restoring splicing balance. This highlights #RNAactivation (RNAa) as a promising #therapeutic strategy for this #raredisease.
📖 doi.org/10.1093/nar/...
#NARBreakthrough