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mrc-mbu.bsky.social
MRC MBU
@mrc-mbu.bsky.social
Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human disease
Reposted by MRC MBU
So great to hear about some of the amazing work being done at the MRC Mitochondrial Biology Unit @mrc-mbu.bsky.social yesterday. There is much more today too.

Hopefully you have been able to catch up with some of the latest in #Mito research.

Open to MRC MBU members only.
October 17, 2025 at 8:46 AM
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Having fun enthusing young and old, expert and novice, about our mitochondria research at Cambridge’s Big Biology Day #PublicEngagement #Outreach @mrc-mbu.bsky.social
October 11, 2025 at 12:01 PM
#BigBiologyDay at Hills Road Sixth Form College- we’re ready!
October 11, 2025 at 8:32 AM
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Exciting study from @frisophagy.bsky.social in @chinnery in the Chinnery lab @mrc-mbu.bsky.social. Congratulations to all authors involved in the study! #mitochondria

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations | Science
www.science.org/doi/10.1126/...
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations
Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...
www.science.org
October 9, 2025 at 9:43 PM
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Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...
October 7, 2025 at 12:43 PM
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We look forward to welcoming Professor Mike Murphy @mrc-mbu.bsky.social at the @cambridgeuni.bsky.social as he delivers our first external seminar of the Easter term.
May 6, 2025 at 7:57 AM
Reposted by MRC MBU
Ever wondered why eating something sugary gives you such an energy boost? 🍰
April 25, 2025 at 10:14 AM
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Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss | EurekAlert! www.eurekalert.org/news-release...
Throwing a ‘spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss
Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the ‘powerhouses’ of our cells, allows us to make the fuel we need from s...
www.eurekalert.org
April 18, 2025 at 9:18 PM
Reposted by MRC MBU
Huge congrats to Pavel Nash on publishing his PhD work! 🎉 We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV. Thanks to the entire team! @mrc-mbu.bsky.social
@mbu-postdocs.bsky.social #MitochondrialDisease #mtDNA
www.embopress.org/doi/full/10....
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine
imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...
www.embopress.org
April 9, 2025 at 7:10 PM
Reposted by MRC MBU
Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture.
By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social

🗞️ doi.org/10.1038/s443...

Read also related N&V by A. Ghifari & M. Ott 👉 doi.org/10.1038/s443...
April 11, 2025 at 2:36 PM
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Looking forward for this exciting meeting in Malta!!! Would be fun with lot of exciting Science!!
@prudentlab.bsky.social we are looking forward to your presentation at #IOSCD25 in Malta🌞 Please share with your followers to let them know early bird registration & talk submission close on 01 May!
Find out more: bit.ly/IOSCD25_Talk...
March 26, 2025 at 11:40 AM
Well done everyone! 😎
We had a great time @cambridgefestival.bsky.social with our friends @mrc-mbu.bsky.social - thanks to everyone who came! Loads more festival events coming up - check out the programme here: www.festival.cam.ac.uk
March 24, 2025 at 1:17 PM
Wishing our team and all our visitors a great day! 🧬🥼
@mrc-mbu.bsky.social all set to entertain the public @cambridgefestival.bsky.social Come and join us at CAST, Cambridge, and learn about our amazing work to understand all things #mitochondria in health and disease
March 22, 2025 at 10:56 AM
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Check out this exciting @faseborg.bsky.social conference with some top quality speakers, talking about #mito DNA mutation & repair! @mrc-mbu.bsky.social @mrcmitocluster.bsky.social
@mbu-postdocs.bsky.social @jellevda.bsky.social @ritahorvath.bsky.social @mito-news.bsky.social
March 5, 2025 at 6:44 PM
What a fabulous week that was! 😎
March 4, 2025 at 2:23 PM
Cambridge signs sustainable research agreement.
www.mrc-mbu.cam.ac.uk/news/cambrid...
February 17, 2025 at 11:51 AM
Hello! 👋
We've joined the Bluesky community to connect again with all those interested in #mitochondria. 😎🥼🔬👩‍🔬👨‍🔬🧪
January 21, 2025 at 1:37 PM