Cambridge Clinical Mitochondrial Research Group
@mitocamb.bsky.social
MitoCAMB brings together a team of clinical researchers focused on mitochondrial and neurodegenerative disease translational research.
mitocamb.medschl.cam.ac.uk
(Photo: Florian Klimm)
mitocamb.medschl.cam.ac.uk
(Photo: Florian Klimm)
A brilliant explainer from The Lily Foundation on the science behind genetic diagnosis in mitochondrial disease — featuring cake as a metaphor! 🍰
youtu.be/MCx4joZJtFY
#Mito #MitochondrialDisease #GeneticTesting #RareDisease #ClinicalResearch #TheLilyFoundation
youtu.be/MCx4joZJtFY
#Mito #MitochondrialDisease #GeneticTesting #RareDisease #ClinicalResearch #TheLilyFoundation
The recipe for explaining how mitochondrial disease is diagnosed #mito #geneticdisorder #raredisease
YouTube video by The Lily Foundation
youtu.be
November 7, 2025 at 2:23 PM
A brilliant explainer from The Lily Foundation on the science behind genetic diagnosis in mitochondrial disease — featuring cake as a metaphor! 🍰
youtu.be/MCx4joZJtFY
#Mito #MitochondrialDisease #GeneticTesting #RareDisease #ClinicalResearch #TheLilyFoundation
youtu.be/MCx4joZJtFY
#Mito #MitochondrialDisease #GeneticTesting #RareDisease #ClinicalResearch #TheLilyFoundation
So great to hear about some of the amazing work being done at the MRC Mitochondrial Biology Unit @mrc-mbu.bsky.social yesterday. There is much more today too.
Hopefully you have been able to catch up with some of the latest in #Mito research.
Open to MRC MBU members only.
Hopefully you have been able to catch up with some of the latest in #Mito research.
Open to MRC MBU members only.
October 17, 2025 at 8:46 AM
So great to hear about some of the amazing work being done at the MRC Mitochondrial Biology Unit @mrc-mbu.bsky.social yesterday. There is much more today too.
Hopefully you have been able to catch up with some of the latest in #Mito research.
Open to MRC MBU members only.
Hopefully you have been able to catch up with some of the latest in #Mito research.
Open to MRC MBU members only.
Bluesky, I am pleased to present to you the main product of postdoc work, published in @science.org ☝️
As it turns out, the very quality control mechanism that can remove mutant mtDNA copies is the one that maintains high mutant burden, or heteroplasmy levels
As it turns out, the very quality control mechanism that can remove mutant mtDNA copies is the one that maintains high mutant burden, or heteroplasmy levels
October 10, 2025 at 9:26 PM
Reposted by Cambridge Clinical Mitochondrial Research Group
👁️Today is World Sight Day – and we’re proud to reshare some incredible news for the mito community. Idebenone is now available for patients with LHON – a breakthrough that could help preserve vision and improve lives.
📖 Read Mary’s story to learn more: https://ow.ly/MZhL50X3wtH
📖 Read Mary’s story to learn more: https://ow.ly/MZhL50X3wtH
October 9, 2025 at 12:05 PM
👁️Today is World Sight Day – and we’re proud to reshare some incredible news for the mito community. Idebenone is now available for patients with LHON – a breakthrough that could help preserve vision and improve lives.
📖 Read Mary’s story to learn more: https://ow.ly/MZhL50X3wtH
📖 Read Mary’s story to learn more: https://ow.ly/MZhL50X3wtH
Congratulations to @lucialugut.bsky.social who passed her PhD with flying colours last week; and with no thesis corrections ☺️🎓👏
October 8, 2025 at 4:10 PM
Congratulations to @lucialugut.bsky.social who passed her PhD with flying colours last week; and with no thesis corrections ☺️🎓👏
Reposted by Cambridge Clinical Mitochondrial Research Group
🔬 Supporting medical research into mitochondrial disease is at the heart of our mission.
Explore our past and current research projects - https://www.thelilyfoundation.org.uk/affected-by-mito/our-research/lily-funded-research-projects/
Together, we’re driving hope through science. 💚
Explore our past and current research projects - https://www.thelilyfoundation.org.uk/affected-by-mito/our-research/lily-funded-research-projects/
Together, we’re driving hope through science. 💚
October 6, 2025 at 11:00 AM
🔬 Supporting medical research into mitochondrial disease is at the heart of our mission.
Explore our past and current research projects - https://www.thelilyfoundation.org.uk/affected-by-mito/our-research/lily-funded-research-projects/
Together, we’re driving hope through science. 💚
Explore our past and current research projects - https://www.thelilyfoundation.org.uk/affected-by-mito/our-research/lily-funded-research-projects/
Together, we’re driving hope through science. 💚
📢 We are recruiting a post-doctoral clinical research associate to join the @lifearc.bsky.social Centre for Rare #Mitochondrial Diseases, supported by @mdukcharity.bsky.social It's an exciting time in mito research! For further details and to apply visit: www.cam.ac.uk/jobs/clinica...
Clinical Research Associate (Fixed Term)
This is a unique opportunity to carry out a period of clinical postdoctoral research focused on developing and validating new treatments and biomarkers for mitochondrial disorders, as part of a new
www.cam.ac.uk
September 26, 2025 at 3:07 PM
📢 We are recruiting a post-doctoral clinical research associate to join the @lifearc.bsky.social Centre for Rare #Mitochondrial Diseases, supported by @mdukcharity.bsky.social It's an exciting time in mito research! For further details and to apply visit: www.cam.ac.uk/jobs/clinica...
Reposted by Cambridge Clinical Mitochondrial Research Group
Rare disease is collectively common, affecting ~1 in 17 people in the UK.
The LifeArc Translational Centres for Rare Disease each tackle a different area of unmet need, but together they're building a stronger rare disease research ecosystem.
Learn more: https://t.ly/zAEj-
#LifeArcTCRD
The LifeArc Translational Centres for Rare Disease each tackle a different area of unmet need, but together they're building a stronger rare disease research ecosystem.
Learn more: https://t.ly/zAEj-
#LifeArcTCRD
LifeArc Translational Centres for Rare Diseases
Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.
t.ly
September 23, 2025 at 8:15 AM
Rare disease is collectively common, affecting ~1 in 17 people in the UK.
The LifeArc Translational Centres for Rare Disease each tackle a different area of unmet need, but together they're building a stronger rare disease research ecosystem.
Learn more: https://t.ly/zAEj-
#LifeArcTCRD
The LifeArc Translational Centres for Rare Disease each tackle a different area of unmet need, but together they're building a stronger rare disease research ecosystem.
Learn more: https://t.ly/zAEj-
#LifeArcTCRD
Reposted by Cambridge Clinical Mitochondrial Research Group
Raising awareness of #mito isn't easy – it’s a complex disease that can be hard to explain 🤔
To help put mito on the map during World Mitochondrial Disease Week, our Research Manager @abioblog.bsky.social is here to explain the disease in a really simple way
Watch, learn and share! 💚
#mitoaware
To help put mito on the map during World Mitochondrial Disease Week, our Research Manager @abioblog.bsky.social is here to explain the disease in a really simple way
Watch, learn and share! 💚
#mitoaware
September 19, 2025 at 3:06 PM
Raising awareness of #mito isn't easy – it’s a complex disease that can be hard to explain 🤔
To help put mito on the map during World Mitochondrial Disease Week, our Research Manager @abioblog.bsky.social is here to explain the disease in a really simple way
Watch, learn and share! 💚
#mitoaware
To help put mito on the map during World Mitochondrial Disease Week, our Research Manager @abioblog.bsky.social is here to explain the disease in a really simple way
Watch, learn and share! 💚
#mitoaware
Reposted by Cambridge Clinical Mitochondrial Research Group
🎉Today marks one year of the LifeArc Translational Centres for Rare Disease.
These four Centres are breaking down the barriers in rare disease research and accelerating the development of new tests and treatments.
#RareDisease #LifeArcTCRD #OneYearOfImpact
These four Centres are breaking down the barriers in rare disease research and accelerating the development of new tests and treatments.
#RareDisease #LifeArcTCRD #OneYearOfImpact
September 16, 2025 at 8:54 AM
🎉Today marks one year of the LifeArc Translational Centres for Rare Disease.
These four Centres are breaking down the barriers in rare disease research and accelerating the development of new tests and treatments.
#RareDisease #LifeArcTCRD #OneYearOfImpact
These four Centres are breaking down the barriers in rare disease research and accelerating the development of new tests and treatments.
#RareDisease #LifeArcTCRD #OneYearOfImpact
A Publication of interest 🎓 🧬 💚
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration. Link to paper: bit.ly/41Xwxg5
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration. Link to paper: bit.ly/41Xwxg5
September 16, 2025 at 9:16 AM
A Publication of interest 🎓 🧬 💚
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration. Link to paper: bit.ly/41Xwxg5
Organelle-tuning condition robustly fabricates energetic mitochondria for cartilage regeneration. Link to paper: bit.ly/41Xwxg5
Reposted by Cambridge Clinical Mitochondrial Research Group
MitoWorld Supports Mitochondrial Disease Week
September 15, 2025 at 11:03 PM
MitoWorld Supports Mitochondrial Disease Week
Reposted by Cambridge Clinical Mitochondrial Research Group
Replication competition drives the selective mtDNA inheritance in Drosophila ovary www.cell.com/cell-reports...
Replication competition drives the selective mtDNA inheritance in Drosophila ovary
Zhang et al. report a novel imaging method that can distinguish mtDNA variants with
single-nucleotide polymorphisms at single-molecule resolution in situ. Using this
method, they visualized dynamics o...
www.cell.com
September 14, 2025 at 3:02 PM
Replication competition drives the selective mtDNA inheritance in Drosophila ovary www.cell.com/cell-reports...
Reposted by Cambridge Clinical Mitochondrial Research Group
It’s here – World Mitochondrial Disease Week! 💚
We’re proud to collaborate with other mito charities across the UK to put mito on the map – let's spread the word together!
👉 See how you can get involved:
🔗 thelilyfoundation.org.uk/charity/get-involved/world-mitochondrial-disease-week
We’re proud to collaborate with other mito charities across the UK to put mito on the map – let's spread the word together!
👉 See how you can get involved:
🔗 thelilyfoundation.org.uk/charity/get-involved/world-mitochondrial-disease-week
September 15, 2025 at 2:21 PM
It’s here – World Mitochondrial Disease Week! 💚
We’re proud to collaborate with other mito charities across the UK to put mito on the map – let's spread the word together!
👉 See how you can get involved:
🔗 thelilyfoundation.org.uk/charity/get-involved/world-mitochondrial-disease-week
We’re proud to collaborate with other mito charities across the UK to put mito on the map – let's spread the word together!
👉 See how you can get involved:
🔗 thelilyfoundation.org.uk/charity/get-involved/world-mitochondrial-disease-week
A discussion about the approval of idebenone for #LHON from the patients’ perspective: www.moorfields.nhs.uk/about-us/new... @moorfieldsbrc.bsky.social @moorfields.bsky.social
Treatment for cause of sudden sight loss now available through the NHS in England - Moorfields Eye Hospital
www.moorfields.nhs.uk
September 11, 2025 at 9:05 AM
A discussion about the approval of idebenone for #LHON from the patients’ perspective: www.moorfields.nhs.uk/about-us/new... @moorfieldsbrc.bsky.social @moorfields.bsky.social
RNIB Connect Radio’s Toby Davey was joined by Patrick Yu-Wai-Man, Professor of Ophthalmology at the University of Cambridge who was involved in the research into using idebenone to treat Leber hereditary optic neuropathy (LHON). Listen here: audioboom.com/posts/876813...
@lilyfoundation.bsky.social
@lilyfoundation.bsky.social
NICE Approves New Treatment for Leber Hereditary Optic Neuropathy (LHON)
NICE, the National Institute for Health and Care Excellence has recently approved new treatment in England for people living with the eye condition Leber hereditary optic neuropathy (LHON) helped by R...
audioboom.com
August 28, 2025 at 9:20 AM
RNIB Connect Radio’s Toby Davey was joined by Patrick Yu-Wai-Man, Professor of Ophthalmology at the University of Cambridge who was involved in the research into using idebenone to treat Leber hereditary optic neuropathy (LHON). Listen here: audioboom.com/posts/876813...
@lilyfoundation.bsky.social
@lilyfoundation.bsky.social
Reposted by Cambridge Clinical Mitochondrial Research Group
👉 'A huge win for the mito community' First ever treatment for a mitochondrial condition that causes sudden vision loss has been approved for use on the NHS in England!
👉 bit.ly/4oHO8m3
@cuh.nhs.uk @mitocamb.bsky.social @cam.ac.uk @moorfieldsbrc.bsky.social @lilyfoundation.bsky.social
👉 bit.ly/4oHO8m3
@cuh.nhs.uk @mitocamb.bsky.social @cam.ac.uk @moorfieldsbrc.bsky.social @lilyfoundation.bsky.social
First ever mitochondrial disease treatment approved by NHS England - NIHR Cambridge Biomedical Research Centre
The first ever treatment for a mitochondrial condition has been approved for use on the NHS in England in a major breakthrough in the fight against the disease.
bit.ly
August 7, 2025 at 11:56 AM
👉 'A huge win for the mito community' First ever treatment for a mitochondrial condition that causes sudden vision loss has been approved for use on the NHS in England!
👉 bit.ly/4oHO8m3
@cuh.nhs.uk @mitocamb.bsky.social @cam.ac.uk @moorfieldsbrc.bsky.social @lilyfoundation.bsky.social
👉 bit.ly/4oHO8m3
@cuh.nhs.uk @mitocamb.bsky.social @cam.ac.uk @moorfieldsbrc.bsky.social @lilyfoundation.bsky.social
This is amazing news!! @camneurodept.bsky.social @mrc-mbu.bsky.social @jellevda.bsky.social @ritahorvath.bsky.social @mito-news.bsky.social
📢 BREAKING NEWS!
The first ever treatment for a mitochondrial disease has been approved for use by NHS England! Idebenone is now available for LHON patients
A huge milestone for the mito community! 💥
www.thelilyfoundation.org.uk/news/first-e...
@mitocamb.bsky.social
The first ever treatment for a mitochondrial disease has been approved for use by NHS England! Idebenone is now available for LHON patients
A huge milestone for the mito community! 💥
www.thelilyfoundation.org.uk/news/first-e...
@mitocamb.bsky.social
August 7, 2025 at 11:34 AM
Reposted by Cambridge Clinical Mitochondrial Research Group
Did you catch the latest about #RAREsummit25? - the programme is shaping up!
RAREsummit alumni, patients pitching research ideas, interactive workshops, networking dinner and more...
Read more here & grab your tickets before they're all snapped up!
www.camraredisease.org/raresummit25...
RAREsummit alumni, patients pitching research ideas, interactive workshops, networking dinner and more...
Read more here & grab your tickets before they're all snapped up!
www.camraredisease.org/raresummit25...
Catch a glimpse of the much anticipated RAREsummit25 programme.
Celebrating 10 years of progress and impact in rare diseases, the UK’s leading multi stakeholder RAREsummit returns to Cambridge
www.camraredisease.org
August 5, 2025 at 11:04 AM
Did you catch the latest about #RAREsummit25? - the programme is shaping up!
RAREsummit alumni, patients pitching research ideas, interactive workshops, networking dinner and more...
Read more here & grab your tickets before they're all snapped up!
www.camraredisease.org/raresummit25...
RAREsummit alumni, patients pitching research ideas, interactive workshops, networking dinner and more...
Read more here & grab your tickets before they're all snapped up!
www.camraredisease.org/raresummit25...
📢 We are hiring a Senior Research Associate in Bioinformatics & Statistical genetics @cam.ac.uk @mrc-mbu.bsky.social @camneurodept.bsky.social @jellevda.bsky.social It's a great time to join this dynamic and world leading team working on #mitochondria Closes 28/8/25
www.cam.ac.uk/jobs/senior-...
www.cam.ac.uk/jobs/senior-...
Senior Research Associate (Fixed Term)
Nuclear-mitochondrial genetic interactions in health and neurodegenerative diseases Fixed-term: The funds for this post are available until 30 September 2028 in the first instance. The University of
www.cam.ac.uk
August 1, 2025 at 1:50 PM
📢 We are hiring a Senior Research Associate in Bioinformatics & Statistical genetics @cam.ac.uk @mrc-mbu.bsky.social @camneurodept.bsky.social @jellevda.bsky.social It's a great time to join this dynamic and world leading team working on #mitochondria Closes 28/8/25
www.cam.ac.uk/jobs/senior-...
www.cam.ac.uk/jobs/senior-...
Kerry & Jelle discuss developing gene therapies for mitochondrial disease — in collaboration with labs around the world! - Watch the Video
bit.ly/3UCF0kC
🌍Sign up to IMPACT to let your voice be heard
bit.ly/4ohHhiN
bit.ly/3UCF0kC
🌍Sign up to IMPACT to let your voice be heard
bit.ly/4ohHhiN
Make an IMPACT - The Lily Foundation
Join IMPACT, The Lily Foundation’s virtual committee for those affected by mitochondrial disease. Share your insights to shape research, care and treatments.
bit.ly
August 1, 2025 at 8:24 AM
Kerry & Jelle discuss developing gene therapies for mitochondrial disease — in collaboration with labs around the world! - Watch the Video
bit.ly/3UCF0kC
🌍Sign up to IMPACT to let your voice be heard
bit.ly/4ohHhiN
bit.ly/3UCF0kC
🌍Sign up to IMPACT to let your voice be heard
bit.ly/4ohHhiN
Love this! @ritahorvath.bsky.social
Zebrafish are helping scientists tackle rare #mitochondrialdiseases like MDDS
In 2018/19, Lily funded research using zebrafish to test treatments
Find out what happened in our latest Research Zone post with Research Manager Maria and Dr Ben Munro
www.thelilyfoundation.org.uk/affected-by-...
In 2018/19, Lily funded research using zebrafish to test treatments
Find out what happened in our latest Research Zone post with Research Manager Maria and Dr Ben Munro
www.thelilyfoundation.org.uk/affected-by-...
August 1, 2025 at 6:05 AM
Love this! @ritahorvath.bsky.social
How to go about designing a leaflet with patients newly diagnosed with mitochondrial disease - a Video from Heather & Elizabeth bit.ly/475t7em
#Mito #PPIE
#Mito #PPIE
July 31, 2025 at 8:19 AM
How to go about designing a leaflet with patients newly diagnosed with mitochondrial disease - a Video from Heather & Elizabeth bit.ly/475t7em
#Mito #PPIE
#Mito #PPIE
Reposted by Cambridge Clinical Mitochondrial Research Group
We’ve been hearing a lot about #mitochondrialdonation today – but what exactly is it?
It’s a groundbreaking fertility technique that helps women with faulty mitochondrial DNA have healthy babies
Want to understand more? Watch our explainer video 👇
www.thelilyfoundation.org.uk/affected-by-...
It’s a groundbreaking fertility technique that helps women with faulty mitochondrial DNA have healthy babies
Want to understand more? Watch our explainer video 👇
www.thelilyfoundation.org.uk/affected-by-...
July 17, 2025 at 11:21 AM
We’ve been hearing a lot about #mitochondrialdonation today – but what exactly is it?
It’s a groundbreaking fertility technique that helps women with faulty mitochondrial DNA have healthy babies
Want to understand more? Watch our explainer video 👇
www.thelilyfoundation.org.uk/affected-by-...
It’s a groundbreaking fertility technique that helps women with faulty mitochondrial DNA have healthy babies
Want to understand more? Watch our explainer video 👇
www.thelilyfoundation.org.uk/affected-by-...
Reposted by Cambridge Clinical Mitochondrial Research Group
Out now:
rdcu.be/evxCv
We've used CoQ10 headgroup intermediates to treat mouse models of a mitochondrial disease and improve the neurological symptoms of a patient with this disease.
Grateful for funding from @damonrunyon.org , Pershing Square Foundation, @americancancersoc.bsky.social, NIH!
rdcu.be/evxCv
We've used CoQ10 headgroup intermediates to treat mouse models of a mitochondrial disease and improve the neurological symptoms of a patient with this disease.
Grateful for funding from @damonrunyon.org , Pershing Square Foundation, @americancancersoc.bsky.social, NIH!
Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy - Nature
Decreased brain coenzyme Q10 levels cause encephalopathy and are associated with neurodegeneration; supplementation with 4-HMA or 4-HB restores coenzyme Q10 synthesis in mice and humans with HPDL vari...
www.nature.com
July 9, 2025 at 5:32 PM
Out now:
rdcu.be/evxCv
We've used CoQ10 headgroup intermediates to treat mouse models of a mitochondrial disease and improve the neurological symptoms of a patient with this disease.
Grateful for funding from @damonrunyon.org , Pershing Square Foundation, @americancancersoc.bsky.social, NIH!
rdcu.be/evxCv
We've used CoQ10 headgroup intermediates to treat mouse models of a mitochondrial disease and improve the neurological symptoms of a patient with this disease.
Grateful for funding from @damonrunyon.org , Pershing Square Foundation, @americancancersoc.bsky.social, NIH!