Michel van den Oever
@moever.bsky.social
Neuroscientist at the CNCR, Vrije Universiteit Amsterdam
Reposted by Michel van den Oever
Excited to share the latest from the lab on the molecular mechanisms of silencing and un-silencing a hippocampal engram ensemble. Was fun using a variant of the EPSILON technique developed by Adam Cohen's lab.
(1/2)
www.sciencedirect.com/science/arti...
(1/2)
www.sciencedirect.com/science/arti...
Molecular mechanisms mediating engram ensemble retrievability state in mice
Engrams, ensembles of neurons that store memories, exist along a continuum of retrievability. Normally, sensory cues can reactivate a latent engram to…
www.sciencedirect.com
October 30, 2025 at 3:32 PM
Excited to share the latest from the lab on the molecular mechanisms of silencing and un-silencing a hippocampal engram ensemble. Was fun using a variant of the EPSILON technique developed by Adam Cohen's lab.
(1/2)
www.sciencedirect.com/science/arti...
(1/2)
www.sciencedirect.com/science/arti...
Reposted by Michel van den Oever
@okaysteve.bsky.social's How to Change a Memory is a disarmingly personal account of the new science of memory manipulation.
The #audiobook, read by the author himself, arrives 4 November.
Preorder it today: press.princeton.edu/books/audio/...
#Neuroscience #Science #Memory
The #audiobook, read by the author himself, arrives 4 November.
Preorder it today: press.princeton.edu/books/audio/...
#Neuroscience #Science #Memory
October 16, 2025 at 6:00 PM
@okaysteve.bsky.social's How to Change a Memory is a disarmingly personal account of the new science of memory manipulation.
The #audiobook, read by the author himself, arrives 4 November.
Preorder it today: press.princeton.edu/books/audio/...
#Neuroscience #Science #Memory
The #audiobook, read by the author himself, arrives 4 November.
Preorder it today: press.princeton.edu/books/audio/...
#Neuroscience #Science #Memory
Reposted by Michel van den Oever
Good morning everyone!
So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory*
www.amazon.com/How-Change-M...
So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory*
www.amazon.com/How-Change-M...
How to Change a Memory: One Neuroscientist’s Quest to Alter the Past
Buy How to Change a Memory: One Neuroscientist’s Quest to Alter the Past on Amazon.com ✓ FREE SHIPPING on qualified orders
www.amazon.com
September 8, 2025 at 1:41 PM
Good morning everyone!
So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory*
www.amazon.com/How-Change-M...
So, I wrote a book (!!) and it’s coming out November 4th in physical and audiobook form. It’s called *How to Change a Memory*
www.amazon.com/How-Change-M...
Reposted by Michel van den Oever
The cost of remembering: engram competition as a flexible mechanism of forgetting.
Our new perspective piece in @cp-trendsneuro.bsky.social, lead by Ryan Lab alumni, Livia Autore. Also with Michael Drew from @utaustin.bsky.social
Trends in Neurosciences www.cell.com/trends/neuro...
Our new perspective piece in @cp-trendsneuro.bsky.social, lead by Ryan Lab alumni, Livia Autore. Also with Michael Drew from @utaustin.bsky.social
Trends in Neurosciences www.cell.com/trends/neuro...
The cost of remembering: engram competition as a flexible mechanism of forgetting
The retention and use of long-term memories is crucial for adaptive behavior. While
stable memories help organisms anticipate outcomes, they may become maladaptive if
not updated to reflect new condit...
www.cell.com
August 15, 2025 at 8:59 AM
The cost of remembering: engram competition as a flexible mechanism of forgetting.
Our new perspective piece in @cp-trendsneuro.bsky.social, lead by Ryan Lab alumni, Livia Autore. Also with Michael Drew from @utaustin.bsky.social
Trends in Neurosciences www.cell.com/trends/neuro...
Our new perspective piece in @cp-trendsneuro.bsky.social, lead by Ryan Lab alumni, Livia Autore. Also with Michael Drew from @utaustin.bsky.social
Trends in Neurosciences www.cell.com/trends/neuro...
Reposted by Michel van den Oever
Beyond happy & proud to have our paper on peptidergic neuromodulation of the #LC out!
This is a project that started with naive intentions & silly curiosity, withstood 1 pandemic & 2 lab moves & made us fall in ❤️ with the most beautiful brain regions of all!! 🔵
www.science.org/doi/10.1126/...
This is a project that started with naive intentions & silly curiosity, withstood 1 pandemic & 2 lab moves & made us fall in ❤️ with the most beautiful brain regions of all!! 🔵
www.science.org/doi/10.1126/...
Neuropeptide Y neurons surrounding the locus coeruleus inhibit noradrenergic system activity to reduce anxiety
Endogenous neuropeptide Y signaling modulates locus coeruleus activity, promoting adaptive responses to stress.
www.science.org
July 23, 2025 at 9:03 PM
Beyond happy & proud to have our paper on peptidergic neuromodulation of the #LC out!
This is a project that started with naive intentions & silly curiosity, withstood 1 pandemic & 2 lab moves & made us fall in ❤️ with the most beautiful brain regions of all!! 🔵
www.science.org/doi/10.1126/...
This is a project that started with naive intentions & silly curiosity, withstood 1 pandemic & 2 lab moves & made us fall in ❤️ with the most beautiful brain regions of all!! 🔵
www.science.org/doi/10.1126/...
Reposted by Michel van den Oever
The most important story in the world right now.
July 25, 2025 at 9:12 AM
The most important story in the world right now.
Reposted by Michel van den Oever
Happening right before our eyes. wapo.st/3GXPS9A
July 24, 2025 at 9:23 PM
Happening right before our eyes. wapo.st/3GXPS9A
Reposted by Michel van den Oever
Our article “Prelimbic cortical excitatory overdrive and inhibitory underdrive accompany environmental suppression of food seeking” recently came out on @npp-journal.bsky.social. tinyurl.com/5xpd9ay5 Want to learn more? The thread is below: 1/n
July 11, 2025 at 6:56 PM
Our article “Prelimbic cortical excitatory overdrive and inhibitory underdrive accompany environmental suppression of food seeking” recently came out on @npp-journal.bsky.social. tinyurl.com/5xpd9ay5 Want to learn more? The thread is below: 1/n
Reposted by Michel van den Oever
Once again, many thanks to all involved in project! Those on bluesky: @katepeters3.bsky.social, @scottkinghorn.bsky.social Finally, special thanks to @moever.bsky.social and Pelle Wilbers at VU Amsterdam for a nice commentary on our article! 🙂https://tinyurl.com/yutzpuv7 14/n
To indulge or enrich: how environmental enrichment affects neurons that promote food seeking - Neuropsychopharmacology
Neuropsychopharmacology - To indulge or enrich: how environmental enrichment affects neurons that promote food seeking
tinyurl.com
July 11, 2025 at 6:56 PM
Once again, many thanks to all involved in project! Those on bluesky: @katepeters3.bsky.social, @scottkinghorn.bsky.social Finally, special thanks to @moever.bsky.social and Pelle Wilbers at VU Amsterdam for a nice commentary on our article! 🙂https://tinyurl.com/yutzpuv7 14/n
Reposted by Michel van den Oever
Thrilled to share new work from the lab, led by Adam Ramsaran:
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com
April 10, 2025 at 4:52 PM
Thrilled to share new work from the lab, led by Adam Ramsaran:
authors.elsevier.com/a/1kva73QW8S...
authors.elsevier.com/a/1kva73QW8S...
Reposted by Michel van den Oever
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪
How Trump is following Project 2025’s radical roadmap to defund science
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page blueprint. Nature read it so you don’t have to.
go.nature.com
March 30, 2025 at 10:27 PM
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪
Reposted by Michel van den Oever
What are we talking about, when we talk about 'representations'?
My undergraduate student, Oyinkansola Olorunleke, is conducting a thesis project on the concept of representation in cognitive sciences & neuroscience.
We are seeking interested participants in the below survey:
tinyurl.com/2e6rcnxv
My undergraduate student, Oyinkansola Olorunleke, is conducting a thesis project on the concept of representation in cognitive sciences & neuroscience.
We are seeking interested participants in the below survey:
tinyurl.com/2e6rcnxv
Representation: Past, Present & Future
This questionnaire is for a final year neuroscience student who is doing her capstone as part of the Representation: Past, Present & Future Project at Trinity College Dublin.
tinyurl.com
March 12, 2025 at 5:57 PM
What are we talking about, when we talk about 'representations'?
My undergraduate student, Oyinkansola Olorunleke, is conducting a thesis project on the concept of representation in cognitive sciences & neuroscience.
We are seeking interested participants in the below survey:
tinyurl.com/2e6rcnxv
My undergraduate student, Oyinkansola Olorunleke, is conducting a thesis project on the concept of representation in cognitive sciences & neuroscience.
We are seeking interested participants in the below survey:
tinyurl.com/2e6rcnxv
Reposted by Michel van den Oever
Registration for the 10th edition of our Summerschool on 'Neural circuit development and plasticity' is open! July 7-11 in Utrecht for MSc and PhD students, and others who are interested. Spread the news! @umcutrecht.bsky.social @utrechtuniversity.bsky.social
March 13, 2025 at 3:51 PM
Registration for the 10th edition of our Summerschool on 'Neural circuit development and plasticity' is open! July 7-11 in Utrecht for MSc and PhD students, and others who are interested. Spread the news! @umcutrecht.bsky.social @utrechtuniversity.bsky.social
Reposted by Michel van den Oever
in our new lab work, we find that:
natural forgetting & induced amnesia share common impaired neural dynamics
this work was funded by multiple #NIH grants that supported students, postdocs, & the science, all with the goal of healing disorders of memory & the brain
www.cell.com/cell-reports...
natural forgetting & induced amnesia share common impaired neural dynamics
this work was funded by multiple #NIH grants that supported students, postdocs, & the science, all with the goal of healing disorders of memory & the brain
www.cell.com/cell-reports...
March 13, 2025 at 4:57 PM
in our new lab work, we find that:
natural forgetting & induced amnesia share common impaired neural dynamics
this work was funded by multiple #NIH grants that supported students, postdocs, & the science, all with the goal of healing disorders of memory & the brain
www.cell.com/cell-reports...
natural forgetting & induced amnesia share common impaired neural dynamics
this work was funded by multiple #NIH grants that supported students, postdocs, & the science, all with the goal of healing disorders of memory & the brain
www.cell.com/cell-reports...
Reposted by Michel van den Oever
Early registration closes tomorrow:
To compensate for recent disruptions in the USA, early registration is extended until February 28th, and abstract submission to March 7th.
Join us in Dublin this May for what promises to be an outstanding scientific meeting.
#EngramsandEnsembles2025
Join us in Dublin this May for what promises to be an outstanding scientific meeting.
#EngramsandEnsembles2025
Announcing the 2025 "Engram and Ensembles in Learning and Memory" meeting, at @tcddublin.bsky.social
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
Half of speakers will be selected from abstracts submitted by trainees. Registration is open below, with discounted rates available until January 31st.
event.fourwaves.com/engramsensem...
February 27, 2025 at 10:56 AM
Early registration closes tomorrow:
Reposted by Michel van den Oever
I am excited to announce that my first first-author paper is now published in a special issue on "Deciphering the memory engram” in Neurobiology of Learning and Memory in which we describe “Structural synaptic signatures of contextual memory retrieval-reactivated hippocampal engram cells".
February 19, 2025 at 4:07 PM
I am excited to announce that my first first-author paper is now published in a special issue on "Deciphering the memory engram” in Neurobiology of Learning and Memory in which we describe “Structural synaptic signatures of contextual memory retrieval-reactivated hippocampal engram cells".
Reposted by Michel van den Oever
Wheeey finally out!
Ever wondered that if the reactivation status of engram cells has an effect on their structure? Yes? Then you should read this nice work!!
Congrats @pantheanemat.bsky.social @moever.bsky.social and all the rest to this nice paper!
Ever wondered that if the reactivation status of engram cells has an effect on their structure? Yes? Then you should read this nice work!!
Congrats @pantheanemat.bsky.social @moever.bsky.social and all the rest to this nice paper!
I am excited to announce that my first first-author paper is now published in a special issue on "Deciphering the memory engram” in Neurobiology of Learning and Memory in which we describe “Structural synaptic signatures of contextual memory retrieval-reactivated hippocampal engram cells".
February 19, 2025 at 4:45 PM
Wheeey finally out!
Ever wondered that if the reactivation status of engram cells has an effect on their structure? Yes? Then you should read this nice work!!
Congrats @pantheanemat.bsky.social @moever.bsky.social and all the rest to this nice paper!
Ever wondered that if the reactivation status of engram cells has an effect on their structure? Yes? Then you should read this nice work!!
Congrats @pantheanemat.bsky.social @moever.bsky.social and all the rest to this nice paper!
Reposted by Michel van den Oever
Hoping this link works:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
January 31, 2025 at 10:02 PM
Hoping this link works:
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Michel van den Oever
The majority of people who responded to a poll in Nature say they’re now using Bluesky. They’re using it to connect with other scientists, keep up to date with other research or researchers, and promote their own research. 🧪
Bluesky’s science takeover: 70% of Nature poll respondents use platform
Roughly 6,000 readers answered our poll, with many declaring that Bluesky was nicer, kinder and less antagonistic to science than X.
go.nature.com
January 24, 2025 at 6:06 PM
The majority of people who responded to a poll in Nature say they’re now using Bluesky. They’re using it to connect with other scientists, keep up to date with other research or researchers, and promote their own research. 🧪