Paul Frankland
@franklandlab.bsky.social
The neuroscience of memory, West Ham Utd, baguettes and other random stuff
Neuroscientist at Hospital for Sick Children/University of Toronto
Neuroscientist at Hospital for Sick Children/University of Toronto
Some morning calm from Toronto
February 3, 2026 at 2:19 PM
Some morning calm from Toronto
Reposted by Paul Frankland
Save the date for the annual "Neural Circuits and Behaviour" satellite conference at the Canadian Association for Neuroscience annual meeting, cohosted by @franklandlab.bsky.social and myself on May 18, 2026. We have a great speaker lineup and will be selecting 4 trainees talks from our registrants!
January 26, 2026 at 6:15 PM
Save the date for the annual "Neural Circuits and Behaviour" satellite conference at the Canadian Association for Neuroscience annual meeting, cohosted by @franklandlab.bsky.social and myself on May 18, 2026. We have a great speaker lineup and will be selecting 4 trainees talks from our registrants!
Same for me-- but work not gym (yet)
January 15, 2026 at 1:09 PM
Same for me-- but work not gym (yet)
It’s snowy out there!
January 15, 2026 at 11:33 AM
It’s snowy out there!
Depends how west is west side… Bricolage is the most west (College and Dufferin). Need to explore further west at some point.
January 13, 2026 at 11:16 PM
Depends how west is west side… Bricolage is the most west (College and Dufferin). Need to explore further west at some point.
It was delicious!
January 13, 2026 at 10:50 PM
It was delicious!
Updated list:
1=. Amadeus
1=. Bricolage
3. Johnson family (NEW ENTRY)
4. Blackbird
5. Jules
6. Nord Lyon
7. Bomou
8. Pompette
9. Petite Thuet
10. Thobors
1=. Amadeus
1=. Bricolage
3. Johnson family (NEW ENTRY)
4. Blackbird
5. Jules
6. Nord Lyon
7. Bomou
8. Pompette
9. Petite Thuet
10. Thobors
January 13, 2026 at 10:49 PM
Updated list:
1=. Amadeus
1=. Bricolage
3. Johnson family (NEW ENTRY)
4. Blackbird
5. Jules
6. Nord Lyon
7. Bomou
8. Pompette
9. Petite Thuet
10. Thobors
1=. Amadeus
1=. Bricolage
3. Johnson family (NEW ENTRY)
4. Blackbird
5. Jules
6. Nord Lyon
7. Bomou
8. Pompette
9. Petite Thuet
10. Thobors
This baguette is spot on. Airy, with near perfect crust. Delicious with some Wensleydale and some Branston! It’s up there with the best baguettes in the city (Bricolage and Amadeus). Need to do a side-by-side comparison.
January 13, 2026 at 10:41 PM
This baguette is spot on. Airy, with near perfect crust. Delicious with some Wensleydale and some Branston! It’s up there with the best baguettes in the city (Bricolage and Amadeus). Need to do a side-by-side comparison.
Excited to continue my exploration of Toronto’s best baguettes. Next up the Johnson family bakery’s baguette (from the brother of @jimjohnsonsci.bsky.social)
January 13, 2026 at 6:44 PM
Excited to continue my exploration of Toronto’s best baguettes. Next up the Johnson family bakery’s baguette (from the brother of @jimjohnsonsci.bsky.social)
Congrats, Sarah!
December 19, 2025 at 11:56 PM
Congrats, Sarah!
Reposted by Paul Frankland
Today was the final day of my three-month stay in Paul and Sheena’s lab.
It was short, but filled with unforgettable moments. I love the lab, the people, and this city.
I can’t put into words how grateful I am for everything. Thank you so much, @franklandlab.bsky.social and @sjo09.bsky.social
It was short, but filled with unforgettable moments. I love the lab, the people, and this city.
I can’t put into words how grateful I am for everything. Thank you so much, @franklandlab.bsky.social and @sjo09.bsky.social
November 28, 2025 at 10:19 PM
Today was the final day of my three-month stay in Paul and Sheena’s lab.
It was short, but filled with unforgettable moments. I love the lab, the people, and this city.
I can’t put into words how grateful I am for everything. Thank you so much, @franklandlab.bsky.social and @sjo09.bsky.social
It was short, but filled with unforgettable moments. I love the lab, the people, and this city.
I can’t put into words how grateful I am for everything. Thank you so much, @franklandlab.bsky.social and @sjo09.bsky.social
These time-dependent shifts in sub-engram engagement indicate that systems consolidation involves reorganization _within_ (as well as across) brain regions.
October 22, 2025 at 6:50 PM
These time-dependent shifts in sub-engram engagement indicate that systems consolidation involves reorganization _within_ (as well as across) brain regions.
We provide evidence for projection-defined 'sub-engrams' that contribute differentially to memory expression at recent and remote delays.
October 22, 2025 at 6:50 PM
We provide evidence for projection-defined 'sub-engrams' that contribute differentially to memory expression at recent and remote delays.
New paper from the lab 🚨
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
authors.elsevier.com
October 22, 2025 at 6:50 PM
New paper from the lab 🚨
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
This adds to an emerging picture that not only do new neurons influence encoding of new memories but they _shape_ and _remodel_ existing memories. These shifts in resolution may facilitate generalization of event based memories beyond the original situation.
October 1, 2025 at 12:39 AM
This adds to an emerging picture that not only do new neurons influence encoding of new memories but they _shape_ and _remodel_ existing memories. These shifts in resolution may facilitate generalization of event based memories beyond the original situation.
Within hippocampal shifts in memory resolution depended on ongoing hippocampal neurogenesis. Blocking neurogenesis prevents time-dependent shifts in memory resolution, preserving hippocampal engrams in high fidelity ‘recent memory’-like states.
October 1, 2025 at 12:39 AM
Within hippocampal shifts in memory resolution depended on ongoing hippocampal neurogenesis. Blocking neurogenesis prevents time-dependent shifts in memory resolution, preserving hippocampal engrams in high fidelity ‘recent memory’-like states.
We found hippocampal engrams were initially high resolution but lost resolution with time. In contrast, cortical engrams were low res and stayed low res over the course of systems consolidation
October 1, 2025 at 12:39 AM
We found hippocampal engrams were initially high resolution but lost resolution with time. In contrast, cortical engrams were low res and stayed low res over the course of systems consolidation
In this paper we tracked the resolution of hippocampal and cortical components of an event memory (modifying a false memory paradigm first developed by @okaysteve.bsky.social). This allowed us to adjudicate between the different theoretical accounts of systems consolidation…
October 1, 2025 at 12:39 AM
In this paper we tracked the resolution of hippocampal and cortical components of an event memory (modifying a false memory paradigm first developed by @okaysteve.bsky.social). This allowed us to adjudicate between the different theoretical accounts of systems consolidation…