Mikel Haggadone, PhD
@mikelhaggadone.bsky.social
NHLBI NRSA postdoc in the Sunny Shin Lab @ UPenn | PennFERBS mentor fellow | metabolism, innate immunity, cell death & inclusive education/mentorship | amino acid enthusiast | sometimes runs very far 🏃♂️
Reposted by Mikel Haggadone, PhD
This week’s neighborhood scientist is Charity Robbins! Check out the link below to read Charity’s rules on how to build the perfect scientist (yes, really!!) neighborhoodscientist.org/posts/2025/l...
Lessons from an Undergraduate Researcher on How to Build the Perfect Scientist (Yes, Really!) – Your Neighborhood Scientist
science news for everyone
neighborhoodscientist.org
September 24, 2025 at 2:52 PM
This week’s neighborhood scientist is Charity Robbins! Check out the link below to read Charity’s rules on how to build the perfect scientist (yes, really!!) neighborhoodscientist.org/posts/2025/l...
Reposted by Mikel Haggadone, PhD
💥 #ImmunometabolismPower! Excited to have this officially out @cp-immunity.bsky.social 💥 We show that pathogens induce the host to produce oxidized lipids which rewire the #metabolism of #macrophages, causing #epigenetic modifications which dampen anti-inflammatory IL-10, exacerbating #inflammation!
Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections
Phagocytes initiate immunity to invading microorganisms by detecting pathogen-associated molecular patterns via pattern recognition receptors. Pathoge…
www.sciencedirect.com
September 10, 2025 at 2:48 PM
💥 #ImmunometabolismPower! Excited to have this officially out @cp-immunity.bsky.social 💥 We show that pathogens induce the host to produce oxidized lipids which rewire the #metabolism of #macrophages, causing #epigenetic modifications which dampen anti-inflammatory IL-10, exacerbating #inflammation!
Reposted by Mikel Haggadone, PhD
If you want to support the work we do, you can donate to my nonprofit @your.neighborhoodscientist.org here: neighborhoodscientist.org
Your Neighborhood Scientist
cultivating community-based conversations around science, science policy, and scientists
neighborhoodscientist.org
September 10, 2025 at 2:16 PM
If you want to support the work we do, you can donate to my nonprofit @your.neighborhoodscientist.org here: neighborhoodscientist.org
Reposted by Mikel Haggadone, PhD
Excited to be featured in today’s @nature.com article about scientists standing up to Trump. I’ve never been one to sit on the sidelines, especially when something I believe so deeply in—science funding that saves lives—is under attack. Read more here: www.nature.com/articles/d41...
September 10, 2025 at 2:15 PM
Excited to be featured in today’s @nature.com article about scientists standing up to Trump. I’ve never been one to sit on the sidelines, especially when something I believe so deeply in—science funding that saves lives—is under attack. Read more here: www.nature.com/articles/d41...
Very stoked for and proud of my dear grad school pal, @jazib.bsky.social. No one pushes themselves harder than this guy! 💪
A beautiful body of work!
A beautiful body of work!
Very excited to share the latest work from the Artis lab! Now out in @natimmunol.nature.com
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
August 18, 2025 at 11:56 PM
Very stoked for and proud of my dear grad school pal, @jazib.bsky.social. No one pushes themselves harder than this guy! 💪
A beautiful body of work!
A beautiful body of work!
Reposted by Mikel Haggadone, PhD
Very excited to share the latest work from the Artis lab! Now out in @natimmunol.nature.com
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
August 15, 2025 at 1:43 PM
Very excited to share the latest work from the Artis lab! Now out in @natimmunol.nature.com
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
Your gut’s neurons aren’t just for digestion; they help heal it too!
nature.com/articles/s41...
I’m very honored to receive the inaugural Penn Postdoctoral Association Mentorship Award for my work with the Class of 2027 PennFERBS undergraduate scholars.
My students mean the absolute world and continue to amaze me with their drive, passion, and eagerness to grow as leaders in STEM. 🙏
My students mean the absolute world and continue to amaze me with their drive, passion, and eagerness to grow as leaders in STEM. 🙏
August 7, 2025 at 11:25 PM
I’m very honored to receive the inaugural Penn Postdoctoral Association Mentorship Award for my work with the Class of 2027 PennFERBS undergraduate scholars.
My students mean the absolute world and continue to amaze me with their drive, passion, and eagerness to grow as leaders in STEM. 🙏
My students mean the absolute world and continue to amaze me with their drive, passion, and eagerness to grow as leaders in STEM. 🙏
Reposted by Mikel Haggadone, PhD
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025.
🔗 ow.ly/rwMU50Wy3Mp
#AAIRESTORE
🔗 ow.ly/rwMU50Wy3Mp
#AAIRESTORE
July 31, 2025 at 3:00 PM
🚨 AAI is proud to announce the launch of the AAI RESTORE Grants Program, an $8M emergency funding initiative to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen in 2025.
🔗 ow.ly/rwMU50Wy3Mp
#AAIRESTORE
🔗 ow.ly/rwMU50Wy3Mp
#AAIRESTORE
Reposted by Mikel Haggadone, PhD
📣The @aai.org allocated $8M RESTORE Grants Program, an initiative that will focus on providing financial support to researchers whose grants were abruptly terminated or frozen in 2025 for reasons unrelated to their scientific merit! 👏
Check the details 👇
#SupportResearch
#Immunology
Check the details 👇
#SupportResearch
#Immunology
$8M RESTORE Grants Program Launched for Researchers Hit by Federal Funding Terminations - AAI News
AAI has launched an $8 million emergency funding initiative called the RESTORE Grants Program to support scientists whose immunology-focused federal research grants were abruptly terminated or frozen ...
news.aai.org
July 31, 2025 at 2:03 PM
📣The @aai.org allocated $8M RESTORE Grants Program, an initiative that will focus on providing financial support to researchers whose grants were abruptly terminated or frozen in 2025 for reasons unrelated to their scientific merit! 👏
Check the details 👇
#SupportResearch
#Immunology
Check the details 👇
#SupportResearch
#Immunology
Reposted by Mikel Haggadone, PhD
Macrophages kind of look like gastly (the Pokémon)
Macrophage photo credit: Cell Wiki
Macrophage photo credit: Cell Wiki
July 31, 2025 at 1:10 AM
Macrophages kind of look like gastly (the Pokémon)
Macrophage photo credit: Cell Wiki
Macrophage photo credit: Cell Wiki
Reposted by Mikel Haggadone, PhD
1/ If you are in the Midwest and ❤️ metabolism, take note!
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
2025 Midwest Metabolism Meeting
Join us for 2025 Midwest Metabolism Meeting at Van Andel Institute Stay informed about exciting upcoming events and activities.
www.vai.org
July 21, 2025 at 9:12 PM
1/ If you are in the Midwest and ❤️ metabolism, take note!
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
This year’s Midwest Metabolism meeting will be held jointly with the Translational Research in Mitochondrial Metabolism in Aging and Disease (TRiMAD) conference.
www.vai.org/event/2025-m...
Reposted by Mikel Haggadone, PhD
Regulation of inflammatory responses by pH-dependent transcriptional condensates @cellcellpress.bsky.social @xuzhoulab.bsky.social @rmedzhitov.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
July 17, 2025 at 4:55 PM
Regulation of inflammatory responses by pH-dependent transcriptional condensates @cellcellpress.bsky.social @xuzhoulab.bsky.social @rmedzhitov.bsky.social
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Mikel Haggadone, PhD
#EpigeneticPower! 💥 #NewPaperAlert! We show @cp-immunity.bsky.social that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2 & blocking #IL10!
Epigenetic silencing of interleukin-10 by host-derived oxidized phospholipids supports a lethal inflammatory response to infections
Upon pathogen detection, phagocytes trigger immunity. This process induces tissue
stress and the formation of host-derived molecules that further tune immune responses.
We show that host-derived oxidi...
dlvr.it
July 17, 2025 at 3:35 PM
#EpigeneticPower! 💥 #NewPaperAlert! We show @cp-immunity.bsky.social that endogenous oxidized lipids decide whether host survives or dies during #sepsis, #ARDS, or Staph infection! Ox lipids bind & inhibit #AKT, boosting inhibitory H3K27 methylation via EZH2 & blocking #IL10!
Reposted by Mikel Haggadone, PhD
Honored to contribute a chapter with co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel & co-senior author @metabailism.bsky.social. Many thanks & congrats to co-editors @tristramryan.bsky.social, @lukeanthonyoneill.bsky.social, & Zbigniew Zaslona on an excellent immunometabolism resource!
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
July 11, 2025 at 1:03 PM
Honored to contribute a chapter with co-1st authors @mikelhaggadone.bsky.social, Brian Goldspiel & co-senior author @metabailism.bsky.social. Many thanks & congrats to co-editors @tristramryan.bsky.social, @lukeanthonyoneill.bsky.social, & Zbigniew Zaslona on an excellent immunometabolism resource!
Honored to contribute a chapter for this awesome immunometabolism resource!
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
July 10, 2025 at 4:26 PM
Honored to contribute a chapter for this awesome immunometabolism resource!
Reposted by Mikel Haggadone, PhD
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
July 10, 2025 at 3:26 PM
Are you interested in #immunometabolism but not sure where to start?
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Introducing our new book “Metabolites as Signals in Immunity and Inflammation”, co-edited with Zbigniew Zasłona and @lukeanthonyoneill.bsky.social (@tcddublin.bsky.social), available now.
shop.elsevier.com/books/metabo...
(1/n)
Reposted by Mikel Haggadone, PhD
Super excited to share my final postdoc paper from Rabinowitz lab- on how whole-body and tissue metabolism changes in viral infection!
pubmed.ncbi.nlm.nih.gov/40581045/
pubmed.ncbi.nlm.nih.gov/40581045/
pubmed.ncbi.nlm.nih.gov
July 7, 2025 at 8:51 PM
Super excited to share my final postdoc paper from Rabinowitz lab- on how whole-body and tissue metabolism changes in viral infection!
pubmed.ncbi.nlm.nih.gov/40581045/
pubmed.ncbi.nlm.nih.gov/40581045/
Reposted by Mikel Haggadone, PhD
Happy July 4th! Here at Your Neighborhood Scientist, we’re excited to highlight American patriotism in a way you might not always think about: scientific research.
neighborhoodscientist.org/posts/2025/j...
neighborhoodscientist.org/posts/2025/j...
July 4, 2025 at 3:48 PM
Happy July 4th! Here at Your Neighborhood Scientist, we’re excited to highlight American patriotism in a way you might not always think about: scientific research.
neighborhoodscientist.org/posts/2025/j...
neighborhoodscientist.org/posts/2025/j...
Reposted by Mikel Haggadone, PhD
We’re doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!
Happy July 4th! Here at Your Neighborhood Scientist, we’re excited to highlight American patriotism in a way you might not always think about: scientific research.
neighborhoodscientist.org/posts/2025/j...
neighborhoodscientist.org/posts/2025/j...
July 4, 2025 at 4:01 PM
We’re doing a July 4 feature all week highlighting how funding science is patriotic (and the incredible researchers doing life changing, tax payer funded research!) Give us a follow!
Reposted by Mikel Haggadone, PhD
Share why doing and supporting science is patriotic at the poll below! 🇺🇸
This 4th of July, we're looking for scientists to share why they're proud to do science in the US. Or maybe you're not a scientist -- but you're proud of the work that US scientists do or you've benefited from US science research. Let us know in the survey below! forms.gle/j8gWMSggKVvJ...
Does your patriotism involve pipettes?
This 4th of July, Your Neighborhood Scientist is asking American scientists and non-scientists why they are proud of scientific research in the US.
Scientists: why are you proud to perform taxpayer-f...
forms.gle
June 27, 2025 at 6:37 PM
Share why doing and supporting science is patriotic at the poll below! 🇺🇸
Reposted by Mikel Haggadone, PhD
June 26, 2025 at 6:54 PM
Reposted by Mikel Haggadone, PhD
Excited to share that our paper examining how GM-CSF potentiates cytokine responses in human monocytes during bacterial infection is now online at the @asm.org journal Infection & Immunity! Congrats to @vvazquez.bsky.social, @mikelhaggadone.bsky.social, & co-authors! journals.asm.org/doi/full/10....
June 17, 2025 at 12:50 PM
Excited to share that our paper examining how GM-CSF potentiates cytokine responses in human monocytes during bacterial infection is now online at the @asm.org journal Infection & Immunity! Congrats to @vvazquez.bsky.social, @mikelhaggadone.bsky.social, & co-authors! journals.asm.org/doi/full/10....
Reposted by Mikel Haggadone, PhD
I had SO much fun speaking about how amazing hearing is at Philly’s @pintofscience.us last night!! Thank you to my amazing lab @geffenlab.bsky.social & @mikelhaggadone.bsky.social for coming out to support! 🧠 🍺
May 22, 2025 at 1:40 PM
I had SO much fun speaking about how amazing hearing is at Philly’s @pintofscience.us last night!! Thank you to my amazing lab @geffenlab.bsky.social & @mikelhaggadone.bsky.social for coming out to support! 🧠 🍺
Reposted by Mikel Haggadone, PhD
Philadelphia friends! We SO NEED to celebrate science. Let's raise a glass to brains.
Join us Wed, 5/21 for Pint of Science. I'll be opening for headliners Dimitris Boufidis, @audreydrotos.bsky.social, & Jacqui Barker. 😊
Tickets (to support the org, $2): pintofscience.us/events/phila...
Join us Wed, 5/21 for Pint of Science. I'll be opening for headliners Dimitris Boufidis, @audreydrotos.bsky.social, & Jacqui Barker. 😊
Tickets (to support the org, $2): pintofscience.us/events/phila...
May 9, 2025 at 4:17 PM
Philadelphia friends! We SO NEED to celebrate science. Let's raise a glass to brains.
Join us Wed, 5/21 for Pint of Science. I'll be opening for headliners Dimitris Boufidis, @audreydrotos.bsky.social, & Jacqui Barker. 😊
Tickets (to support the org, $2): pintofscience.us/events/phila...
Join us Wed, 5/21 for Pint of Science. I'll be opening for headliners Dimitris Boufidis, @audreydrotos.bsky.social, & Jacqui Barker. 😊
Tickets (to support the org, $2): pintofscience.us/events/phila...
Reposted by Mikel Haggadone, PhD
I remember in 1989 when our basketball coach announced he was leaving after the NCAAs and was told “Nope. You’re out now.” It’s time for Ono to be told that. Let’s have someone as interim who is reflecting Michigan values, fighting for us, and advocating for higher ed. We don’t need to wait.
NEW: Fresh off announcing his departure for the University of Florida, outgoing University of Michigan President Santa Ono has had his name removed from the American Assoc of Colleges and Universities academic freedom letter he signed barely two weeks ago. talkingpointsmemo.com/edblog/outgo...
Outgoing UMich Prez Santa Ono Pulls His Name from Academic Freedom Letter
Over the weekend University of Michigan President Santa Ono announced that he...
talkingpointsmemo.com
May 8, 2025 at 10:53 AM
I remember in 1989 when our basketball coach announced he was leaving after the NCAAs and was told “Nope. You’re out now.” It’s time for Ono to be told that. Let’s have someone as interim who is reflecting Michigan values, fighting for us, and advocating for higher ed. We don’t need to wait.