MichaelMcMurray lab
@mcmurraylab.bsky.social
Official account of Michael McMurray’s lab in the Dept. Cell and Developmental Biology at the University of Colorado Anschutz Medical Campus. We study septin proteins, folding/assembly of multi subunit protein complexes, & various aspects of yeast biology
Reposted by MichaelMcMurray lab
📢 Postdoc position: Biochemistry & Bacterial cell biology
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
November 10, 2025 at 6:15 PM
📢 Postdoc position: Biochemistry & Bacterial cell biology
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
Reposted by MichaelMcMurray lab
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 10, 2025 at 5:47 PM
Wound healing is a hallmark feature of all life, including single cells. In a new preprint, Ambika Nadkarni @biochembika.bsky.social investigates a new dimension in cellular wound healing: how cells recover AFTER the wound has been closed
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Somehow only today noticed this post from August about our MBoC paper on yeast spore polarity... it's not too late to read about it if you have an interest in cell polarity, yeast spores, and/or septins!
In yeast spores, polarity emerges from a different playbook.
Dr. Michael McMurray (University of Colorado Anschutz) reveals how Bud8, Bud5, and Cdc42 machinery help spores establish polarity without relying on classic cortical landmarks.
www.molbiolcell.org/doi/10.1091/... #ASCB #CellBiology
Dr. Michael McMurray (University of Colorado Anschutz) reveals how Bud8, Bud5, and Cdc42 machinery help spores establish polarity without relying on classic cortical landmarks.
www.molbiolcell.org/doi/10.1091/... #ASCB #CellBiology
November 7, 2025 at 11:29 PM
Somehow only today noticed this post from August about our MBoC paper on yeast spore polarity... it's not too late to read about it if you have an interest in cell polarity, yeast spores, and/or septins!
The CloneChecker kit from ThermoScientific is great: suspend an E. coli colony in Green Buffer, boil and add restriction digest buffer and enzyme, digest 30 min, run entire reaction on gel and there’s visible bands. Seems like we should be able to guess what’s in this proprietary buffer. Ideas?
October 15, 2025 at 10:05 PM
The CloneChecker kit from ThermoScientific is great: suspend an E. coli colony in Green Buffer, boil and add restriction digest buffer and enzyme, digest 30 min, run entire reaction on gel and there’s visible bands. Seems like we should be able to guess what’s in this proprietary buffer. Ideas?
Reposted by MichaelMcMurray lab
I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word.
share.google/gukbzS1zdIx6...
share.google/gukbzS1zdIx6...
Postdoctoral Researcher in Plant Evolutionary Genomics
The postdoctoral researcher will work in Dr. Michael Grillo’s plant evolutionary genetics lab. The goal of this research project is to understand the genomic basis of plant-microbiome variation in leg...
share.google
October 10, 2025 at 6:11 PM
I am hiring a postdoc to examine the genomic and evolutionary basis of plant microbiome variation in legumes. There are opportunities to gain teaching experience. Chicago is a great city to live in! Please help spread the word.
share.google/gukbzS1zdIx6...
share.google/gukbzS1zdIx6...
Reposted by MichaelMcMurray lab
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
The genomic basis of symbiotic integration at University of Bath on FindAPhD.com
PhD Project - The genomic basis of symbiotic integration at University of Bath, listed on FindAPhD.com
www.findaphd.com
October 9, 2025 at 9:39 AM
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
Reposted by MichaelMcMurray lab
Now that I'm settled in at @umasschan.bsky.social, I'm hiring at all levels: grad students, post-docs, and software engineers/bioinformaticians!
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
October 7, 2025 at 3:24 PM
Now that I'm settled in at @umasschan.bsky.social, I'm hiring at all levels: grad students, post-docs, and software engineers/bioinformaticians!
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
The goal of my lab is to understand the regulatory role of every nucleotide in our genomes and how this changes across every cell in our bodies.
Something I’ve always wondered: why do so many (most?) researchers who use lab ice (i.e., in ice buckets to keep reagents cold) discard the ice in the sink rather than draining off any water and returning the ice to the ice machine? Do you think the ice is somehow “contaminated”, or something? 🧐
October 7, 2025 at 3:18 PM
Something I’ve always wondered: why do so many (most?) researchers who use lab ice (i.e., in ice buckets to keep reagents cold) discard the ice in the sink rather than draining off any water and returning the ice to the ice machine? Do you think the ice is somehow “contaminated”, or something? 🧐
Reposted by MichaelMcMurray lab
October 3, 2025 at 1:52 AM
Reposted by MichaelMcMurray lab
RFK Jr. poses a danger to the health and safety of all Americans. From cutting critical cancer research to spreading lies about Tylenol, it’s very clear RFK Jr. is not fit to serve.
That’s why I’m drafting articles of impeachment to remove him from office.
That’s why I’m drafting articles of impeachment to remove him from office.
September 26, 2025 at 3:28 PM
RFK Jr. poses a danger to the health and safety of all Americans. From cutting critical cancer research to spreading lies about Tylenol, it’s very clear RFK Jr. is not fit to serve.
That’s why I’m drafting articles of impeachment to remove him from office.
That’s why I’m drafting articles of impeachment to remove him from office.
Reposted by MichaelMcMurray lab
Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...
Leaflet-specific phospholipid imaging using genetically encoded proximity sensors - Nature Chemical Biology
An approach combining bioorthogonal chemistry with genetically encoded fluorogen-activating proteins enables subcellular imaging of phospholipids and glycans, as well as the visualization of lipid tra...
www.nature.com
September 15, 2025 at 6:03 PM
Very excited to share new work out today in @natchembio.nature.com on a new approach - FACES - for selectively imaging of phospholipids and other biomolecules at spatial resolutions down to individual membrane leaflets (1/n) www.nature.com/articles/s41...
Reposted by MichaelMcMurray lab
Asking BlueSky for help: For a review, I am trying to accurately credit the first paper that measured pairwise 3D distances between 2 pieces of DNA on the same chromosome (or cosmid). Is Trask 1989 the first?
I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...
I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...
September 21, 2025 at 6:54 PM
Asking BlueSky for help: For a review, I am trying to accurately credit the first paper that measured pairwise 3D distances between 2 pieces of DNA on the same chromosome (or cosmid). Is Trask 1989 the first?
I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...
I know of earlier single-locus papers (1982).
www.sciencedirect.com/science/arti...
Reposted by MichaelMcMurray lab
Josh Morgan discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. rupress.org/jcb/article/...
📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...
📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...
September 19, 2025 at 2:04 PM
Josh Morgan discusses how progress in cell biology is hindered by significance testing and the need for a shift to effect size estimation. rupress.org/jcb/article/...
📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...
📕 In #Reproducibility and Best Practices in Cell Biology: rupress.org/jcb/collecti...
Reposted by MichaelMcMurray lab
Checkout our new preprint with the @rokaslab.bsky.social!:
www.biorxiv.org/content/10.1...
doi: doi.org/10.1101/2025...
www.biorxiv.org/content/10.1...
doi: doi.org/10.1101/2025...
Discovery of additional ancient genome duplications in yeasts
Whole genome duplication (WGD) has had profound macroevolutionary impacts on diverse lineages[1][1],[2][2], preceding adaptive radiations in vertebrates[3][3]–[5][4], teleost fish[6][5],[7][6], and an...
www.biorxiv.org
September 17, 2025 at 2:20 AM
Checkout our new preprint with the @rokaslab.bsky.social!:
www.biorxiv.org/content/10.1...
doi: doi.org/10.1101/2025...
www.biorxiv.org/content/10.1...
doi: doi.org/10.1101/2025...
Reposted by MichaelMcMurray lab
On #ScienceUnderSeige BY @peterhotezmdphd.bsky.social @michaelemann.bsky.social @latimes.com @hiltzikm.bsky.social www.latimes.com/business/sto...
September 15, 2025 at 2:13 PM
Reposted by MichaelMcMurray lab
We present a simple method to easily increase the imageable depth of an expansion microscopy gel on a typical inverted microscope ten-fold, using some carefully placed FEP film and a water dipping objective lens:
September 15, 2025 at 8:42 AM
We present a simple method to easily increase the imageable depth of an expansion microscopy gel on a typical inverted microscope ten-fold, using some carefully placed FEP film and a water dipping objective lens:
This kind of discovery is so important and illuminating!! Congratulations to the authors
🧬Want the full story of our paper without the science jargon? Our @ucdavis.bsky.social department broke down our "cells are crowded AND constrained" findings in plain English! Perfect explanation of why worm cells are nothing like cultured cells 🪱🌠
September 10, 2025 at 7:47 PM
This kind of discovery is so important and illuminating!! Congratulations to the authors
Reposted by MichaelMcMurray lab
OK--fluorescent protein friends. We want an antibody to TagRFP that works in immunofluorescence. Any suggestions? Re-post please
September 9, 2025 at 6:43 PM
OK--fluorescent protein friends. We want an antibody to TagRFP that works in immunofluorescence. Any suggestions? Re-post please
Reposted by MichaelMcMurray lab
We're hiring a tech for a project focused on the impact of genetic background on genetics and evolution. If you like doing lots of microbial evolution experiments and are good at bioinformatics/computation, this might be for you. aprecruit.ucsf.edu/JPF05782
Madhani Lab – Junior/Assistant Specialist
University of California, San Francisco is hiring. Apply now!
aprecruit.ucsf.edu
September 4, 2025 at 7:42 PM
We're hiring a tech for a project focused on the impact of genetic background on genetics and evolution. If you like doing lots of microbial evolution experiments and are good at bioinformatics/computation, this might be for you. aprecruit.ucsf.edu/JPF05782
Reposted by MichaelMcMurray lab
WARNING WARNING WARNING
#ResearchAdmini
I am hearing reports of NIH Awards being issued with ~15% indirect cost rate without comment. I believe the hope is that they will be accepted with noticing this.
#ResearchAdmini
I am hearing reports of NIH Awards being issued with ~15% indirect cost rate without comment. I believe the hope is that they will be accepted with noticing this.
a woman stands in front of a white board with the words you need to be careful written on it
ALT: a woman stands in front of a white board with the words you need to be careful written on it
media.tenor.com
August 25, 2025 at 7:23 PM
WARNING WARNING WARNING
#ResearchAdmini
I am hearing reports of NIH Awards being issued with ~15% indirect cost rate without comment. I believe the hope is that they will be accepted with noticing this.
#ResearchAdmini
I am hearing reports of NIH Awards being issued with ~15% indirect cost rate without comment. I believe the hope is that they will be accepted with noticing this.
Reposted by MichaelMcMurray lab
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
August 20, 2025 at 3:17 PM
Pro tip for getting your data into SGD and other knowledgebases: don't hide the data in the supplemental info in PDF format. Put it in Excel with stable identifiers like SGDIDs and systematic_names (ex. YFL039C) in addition to gene names. #yeast #modelOrganism #getYourDataOutGetCited
Reposted by MichaelMcMurray lab
Here you go..." Why strong mentorship was essential for my career success in science" JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors. www.nature.com/articles/d41...
Why strong mentorship was essential for my career success in science
JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors.
www.nature.com
August 20, 2025 at 3:39 AM
Here you go..." Why strong mentorship was essential for my career success in science" JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors. www.nature.com/articles/d41...
Reposted by MichaelMcMurray lab
If you are an "FFPE expert", could I ask you a few questions?
Let me know and I'll DM you 😊
Please RT
Let me know and I'll DM you 😊
Please RT
July 28, 2025 at 12:54 PM
If you are an "FFPE expert", could I ask you a few questions?
Let me know and I'll DM you 😊
Please RT
Let me know and I'll DM you 😊
Please RT
Reposted by MichaelMcMurray lab
Having a 5 percentile R01 grant not being funded sucks so much. And having it falling through the cracks because of delays in council meetings and other administrative shenanigans even more.
July 24, 2025 at 9:01 PM
Having a 5 percentile R01 grant not being funded sucks so much. And having it falling through the cracks because of delays in council meetings and other administrative shenanigans even more.